201 results about "Ectopic sebaceous glands" patented technology

A method and apparatus are provided for targeting lipid-rich tissue to effect a desired, the method / apparatus involving irradiating the lipid-rich tissue with energy at a wavelength preferentially absorbed by lipid cells, such wavelength being preferably in a band between 880 nm and 935 nm, 1150 nm and 1230 nm, 1690 nm to 1780 nm, or 2250 nm to 2450 nm with a fluence and duration sufficient to achieve a desired treatment. For preferred embodiments, the irradiation wavelength is between 900–930 nm, 1190–1220 nm, 1700–1730 nm, or 2280–2350 nm. The method and apparatus may for example be used to target one or more sebaceous glands for the treatment of acne or hair removal, to target subcutaneous fat for removal thereof or for targeting fat on anatomical elements for various purposes.

A method and system for ultrasound treatment of acne and sebaceous glands are provided. An exemplary method and system are configured for targeted treatment of sebaceous glands in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and / or through use of focused, unfocused, or defocused ultrasound at various spatial and temporal energy settings. An exemplary method and system can be configured to produce regions of heating and damage by destroying the function of sebaceous glands within a user-specified treatment layer depth associated with the glands to be treated. In addition, an exemplary method and system can be configured to produce regions of heating and damage within the treatment layer in spatially defined patterns, rather than heating and destroying the entire volume of the target layer of tissue. Further, an exemplary method and system can be configured to specifically aim such regions of heating and damage within the treatment layer, to occur at the same location as the secretory portion of sebaceous glands.

Light treatments of sebaceous gland disorders with 5-aminolevulinic acid and photodynamic therapy are disclosed. A preferred treatment includes topical application of 5-aminolevulinic acid to the skin followed by light exposures with repeated treatment at various intervals. At low doses of ALA and photodynamic therapy (PDT) in single or multiple treatments, improvement in the sebaceous gland disorder, e.g., acne, provides the discovery that diminishment in sebum secretion and the eradication of bacteria occurs. At high doses of ALA and a single high energy PDT treatment, permanent changes to the sebaceous gland and sebum secretion have been discovered.

The present invention is directed to a method and apparatus for delivering substances, e.g., therapeutic substances, into openings on or near a skin surface, such as hair follicles, pores and / or into sebaceous glands. This can be achieved by using an apparatus to direct a substance into the openings under pressure via one or more nozzles or slits. A portion of the sebum present in the hair follicle is optionally heated and / or removed, e.g. using low-pressure conduit located on the lower surface of the apparatus, before introducing the therapeutic substance.

A method of selectively enhancing photothermal sebaceous gland disruption and treatment of acne is disclosed. The method provides for alleviation of the acne symptoms as well as preventing acne recurrence and new acne from occurring.

Methods of mitigating acne include exposing an expanse of skin to light; terminating the exposure of the skin to the light; and applying a benefit agent to the expanse of skin after a delay following the termination. The light exposure may be for a period of less than about one hour, and the light may be suitable for either (a) exciting porphyrins associated with the expanse of skin into an energetic state suitable for destroying acne-causing micro-organisms, or (b) for heating lipids present in sebaceous glands within the expanse of skin in order to modulate the flow of sebum in said sebaceous glands, or (c) for reducing inflammation. The benefit agent is suitable for either (a) providing anti-microbial action that is complementary to either said modulating of said sebum by said band of light, or complementary to said reduction of inflammation by said light or (b) providing sebum-modulating action that is complementary to either said destruction of said acne-causing microorganisms or complementary to said reduction of inflammation by said light; or (c) providing anti-inflammation that is complementary to either said modulating of said sebum by said band of light, or complementary to said destruction of said acne-causing microorganisms. These treatments may be repeated, as necessary.

The invention describes a treatment for skin wherein a pattern of holes is ablated in a selected region of skin tissue using an optical source. Substantially nonablative energy is delivered to the selected region to at least two holes in the pattern to thermally heat a target in or just beneath the skin, such as hair follicles, sebaceous glands, or subcutaneous fat. The invention may further be improved by adding a feedback mechanism that adapts the nonablative energy in response to a measurement enabled by the ablation of holes. The apparatus may include a positional sensor to provide additional dosage control, particularly when the inventive method is used with a continuously movable handpiece.

Disclosed herein are apparatuses, systems, kits, and methods for treating skin, such as skin tightening or for treating diseases, disorders, and conditions that would benefit from tissue area or volume reduction, skin restoration, skin tightening, skin lifting, and / or skin repositioning and / or for generally improving skin function or appearance (e.g., the removal of unwanted skin features or irregularities such as sebaceous glands, sweat glands, hair follicles, necrosis, and fibrosis). Such apparatuses, systems, kits, and methods comprise an apparatus having a handheld main body and a detachably attachable tip comprising one or more needles.

An improved method and preparation for the treatment of acne and hirsutism comprises topically applying an effective amount of a saw palmetto berry extract, and preferably one or more low irritability constituents that enhance penetration of the extract into hair follicle sebaceous glands. The low irritability penetration aid may be selected from the group consisting of adapalene, tretinoin, tretinoin gel microsponges, retinaldehyde, retinol, tazarotene, beta hydroxy acids (salicylic acid), azelaic acid, and alpha hydroxy acids (glycolic acid) as well as polyolprepolymer-2.

An improved method and preparation for the treatment of acne and hirsutism comprises topically applying an effective amount of a saw palmetto berry extract, in combination with two classes of low irritability penetrating agents that enhance penetration of the extract into hair follicles and sebaceous glands. The low irritability penetration agents are selected from the group (A) comedolytics consisting of adapalene, tretinoin, tretinoin gel microsponges, retinaldehyde, retinol, and tazarotene, and (B) keratinolytics consisting of the beta hydroxy acid, salicylic acid, and the alpha hydroxy acid, glycolic acid. Polyolprepolymer-2 may be incorporated into the preparation as well.

This disclosed method improves the accuracy of testing blood for the levels of contaminants, such as lead, cadmium and mercury, in individuals. The method comprises cleaning the area where the skin will be penetrated to obtain the blood sample to remove the contaminant to be measured in the blood. The cleansing is accomplished with a cleanser formulated to remove the contaminant to be measured in the blood from the surface of the skin, the pores, sweat ducts, hair follicles and sebaceous gland ducts. The method reduces contamination of the blood sample by contaminants on, and / or in the portion of the skin through which the blood sample is drawn. A premoistened wipe can also be used that mobilizes heavy metals from the skin surface, the skin pores, sweat ducts, hair follicles and sebaceous gland ducts, and is formed with a wipe substrate material selected for its affinity to bind the toxic materials.

The invention discloses an external preparation for skin. The preparation comprises components including a pseudo-ceramide compound, a steroid, fatty acid and N-acylethanolamine and contains no grease. Through the manner, the preparation can be used for skin care and maintenance as well as treatment of some skin symptoms, particularly dermatitis symptoms such as atopic dermatitis, eczema, acne, seborrhoeic dermatitis, contact dermatitis, allergic dermatitis, solar dermatitis and the like, particularly in areas where sebaceous glands are abundant, such as faces, scalp, necks, chests, backs and buttocks.

The present invention relates to the field of medical technology, and in particular relates to a category of novel sulphonyl substituted xanthene ketone compounds that have a structural formula as shown in the right, a preparation method and application thereof. The compound has high inhibitory activity for ACAT1 / ACAT2; most of the compounds have high inhibitory activity for acyl coenzyme A cholesterol acyltransferase (ACAT). The compounds can be used for preparing anti-atherosclerosis drug combination. Furthermore, the compounds can be used as a preventive or a treating agent of such diseases as angina, myocardial infarction, cerebral infarction, apoplexy, Alzheimer's disease, acute coronary syndrome, PTCA or restenosis of coronary artery after a bracket is arranged. The compounds can be used as a treating agent to adjust the function of sebaceous glands of the skin and inhibit the excessive generation of sebum. And the compounds can be used for treating such diseases as acne-like damage caused by oily skin, acne, seborrhea and corticosteroids.

The invention discloses a composition for removing acnes and application of the composition in cosmetics. The composition is prepared from the following components: a paeony extract, a cucumber extract, a feverfew extract, a yellowish sophora root extract, a hamamelis virginiana extract, a lonicera tragophylla extract, tea tree leaf oil and oligosaccharide. The composition disclosed by the invention further comprises one or the combination of several of nicotinamide, panthenol, allantoin and oat kernel oil. The composition is suitable for acne type skins and helps users resist and relieve inflammation caused by exuberant sebum secretion, sebaceous gland obstruction and mass propagation of propionic acid acne bacillus and to repair the skin. According to the application of the composition for removing the acnes in medicines or cosmetics, the composition can be made into liquid, gel, emulsion or paste and other forms.

This invention is directed to analogs of 5-(tetradecyloxy)-2-furancarboxylic acid (TOFA) and their use in the treatment of dermatological disorders or conditions characterized by sebaceous gland hyperactivity, such as acne and oily skin, and other dermatological disorders and conditions. This invention is also directed to pharmaceutical compositions comprising analogs of TOFA and a pharmaceutically acceptable excipient for dermatological or oral administration. Formula (I)

The invention discloses an oil-control cosmetic composite, wherein the formula comprises the following components in percentage by weight: 0.01-10% of water-soluble zinc salt, 0.1-8% of oil-absorbing powder, 0.1-15% of royal jelly extract, 0.1-20% of natural Chinese herbal medicine extract, 0.32-47% of cosmetic base materials, and the residue of deionized water. In the invention, the composite can reduce the oil secretion, absorb skin oil, continuously control the secretion of the skin oil and have great tenderness; and proved by experiment, the composite has better capability of controlling active sebaceous glands in comparison with the market products, greatly reduces the secretion volume of the oil and is effective continuously.

The invention discloses an acne removing gel. The acne removing gel is prepared from, by mass, 8-10% of wetting agent, 15-20% of skin conditioner, 0.5-0.8% of preservative, 0.1-0.4% of thickening agent, 0.1-0.3% of neutralizing agent, 0.03-0.08% of solubilizing agent and 68.42-76.27% of water. The total mass percentage of the components is 100%. The invention further discloses a preparing method of the acne removing gel. By adding the skin conditioner, activation of the sebaceous gland can be prevented, and skin cuticle can be improved. The acne removing gel also has sterilizing, anti-inflammation and antioxidant effects, can make skin healthy, and is suitable for various kinds of skin.

A non-surgical device used to duplicate a protruding or non-protruding nipple and areola containing sebaceous glands (Montgomery follicles) and sweat glands, creating the most natural-looking nipple and areola possible. The device will function as a nipple prosthesis, nipple enhancer or a nipple protector. At the user's discretion, the vertex can be shaped in several polyhedral angles, such as rounded, squared and pointed. The nipple portion may be custom sized by cutting for either erect, non-erect, rounded, squared or have a pointed look or it may be left in its original size.

The invention discloses an anti-dropping and hair reviving shampoo. The anti-dropping and hair reviving shampoo comprises the following components in part by weight: 65 to 85 parts of shampoo substrate and 15 to 35 parts of plant extract. The invention also discloses a preparation method for the anti-dropping and hair reviving shampoo. The shampoo can suppress the secretion of sebaceous glands, sterilizes and restrains pathogen, activates hair cells, promotes hair cell division, and can fundamentally solve the problems of baldness, hair growth and the like effectively.

A method of controlling an operation of a portable skin treatment device, the method including: if a control button of the treatment device is pressed, heating a heater to prepare heating of a tip of the treatment device in a predetermined temperature range; and if heating of the tip is completed, turning on a light source disposed inside a housing of the treatment device and performing light irradiation treatment of irradiating light onto the skin through the tip together with heat. By using the method of controlling the operation of the portable skin treatment device by applying heat to the skin area of a disease of sebaceous glands such as acne etc. or itch and by irradiating light onto the skin area, treatment effects can be improved, and the fact that a user is getting treatment can be more realistically recognized.

The invention relates to mild oil-control shampoo with cool feeling. The shampoo comprises the following ingredients in percentage: (A) an ampholytic surfactant accounting for 5.0-40% of weight of a composition; (B) an alkyl polyglycoside surfactant accounting for 1.0-10.0% of weight of the composition; (C) an oil-control active matter accounting for 0.05-8% of weight of the composition, wherein the oil-control active matter is a composition of water, nicotinamide, a yeast extract, an aesculus hippocastanum extract, ammonium glycyrrhetate, panthenol, propylene glycol, zinc gluconate and caffeine; (D) mint lactate accounting for 0.1-10% of weight of the composition; (E) a cationic polymer accounting 0.05-3.0% of weight of the composition; and (F) the balance being water. The oil-control composition disclosed by the invention not only can remove sebum from scalp but also can effectively regulate the activity of sebaceous gland, so as to bring about cool and clean feeling to a user, keep hair fresh and delay re-greasiness time of hair; and the shampoo is mild and nonirritant.

The invention discloses a berberis julianae schneid extracting solution and a preparation method and application thereof. The berberis julianae schneid extracting solution prepared by means of water extraction has the remarkable effects of resisting bacteria, diminishing inflammation, regulating internal secretion, promoting skin cell metabolism and improving local blood circulation. With the characteristic, the berberis julianae schneid extracting solution has the effects of repairing injured cells, restraining sebum secretion, dredging facial hair follicle and sebaceous gland holes and protecting keratoderma. By applying the berberis julianae schneid extracting solution to cosmetics, the effects of remarkably repairing and protecting sensitive and acne skin are achieved.

The invention provides a composition for controlling atrichia. Raw materials of the composition comprise the following ingredients: angelica sinensis, hurricane lamp, salvia miltiorrhiza bge, radix sophorae flavescentis, cortex lycii radicis, rhizoma zingiberis, rhizoma drynariae, notopterygium root, pawpaw, rhizoma ligustici wallichii, common dodder, rhizoma gastrodiae, ginseng, lopseed, radix paeoniae alba and spatholobus stem. The composition for controlling the atrichia of the invention can enhance the scalp blood circulation, can particularly and effectively inhabit the sebaceous gland exudation, can eliminate the scalp grease, can improve the hair follicle growth environment, and can promote the discharge of decay hair. The composition for controlling the atrichia contains a certain number of hair growing and developing ingredients, and the connection effect in the hair growing link can be realized on the basis of fast atrichia prevention.

The invention belongs to the technical field of tissue engineering, and discloses artificial skin and a preparation method thereof. The artificial skin comprises epithelial cells, dermal cells and a biological bracket material. The preparation method comprises the following steps: compounding the dermal cells into the biological bracket material; inoculating the epithelial cells on the surfaces of the dermal cells; carrying out cultivation. As the artificial skin comprises a corium layer, an epidermal layer and active cells, and the epidermal layer comprises cuticle, the artificial skin is similar to normal skin, human skin with complete functions can be regenerated after the transplanting of the artificial skin, and the regenerated skin comprises skin appurtenant organs such as hair and sebaceous glands. Therefore, the artificial skin can be used for treating skin defect caused by inflammation, ulcer, burning and scalding, and also can be used for preparation of skin models used for disease researches, medicine testing and screening, cosmetic testing, or the like.

The invention relates to a method and a formula for promoting hair growth. The method for promoting the hair growth is characterized by comprising the following steps: firstly fumigating the head by adopting a soak solution of fumigating powder; secondly, smearing a toning liquid agent with special effect on the head and expelling toxins by combining a toxin expelling instrument; thirdly, smearing an intensive scalp care liquid agent on the to-be-treated parts of the head and carrying out radiation on main and collateral channels of the whole head; fourthly, spraying a hair root activin agent to the to-be-treated parts, wrapping the whole head by adopting a piece of preservative paper, heating by combining a four-core heat energy lamp, and then irradiating by adopting a fire cloud tunnel instrument; and finally smearing a hair drying and thickening essence liquid agent on to-be-treated scalps and hair roots, wrapping the whole head by adopting a piece of preservative paper, heating by virtue of the four-core heat energy lamp, and then introducing. The method for promoting the hair growth is simple, safe and reliable in operation and can be used by combining with the formula, so that a medicine can contact skin of the head under the fumigation action, blood capillaries are expanded under the actions of temperature and pressure, medicinal ingredients are absorbed through permeation by virtue of sweat glands and sebaceous glands on skin and act on the to-be-treated positions under the blood circulation action, the main and collateral channels are stimulated to achieve the aim of treatment, alopecia formed by nature and nurture can be effectively treated, and the effects of growing hairs and removing hair oil and scalp acnes can be realized.

The invention relates to a traditional Chinese medicine composition for cosmetics cream and facial mask and a mixed extraction solution of the traditional Chinese medicine composition. The traditionalChinese medicine composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 10 to 20 parts of herba centellae, 10 to 12 parts of radix asparagi, 8 parts ofherba cynomorii, 10 to 12 parts of semen cuscutae, 10 to 15 parts of licorice roots, 10 to 15 parts of radix salviae miltiorrhizae, 12 to 15 parts of radix paeoniae alba, 12 to 15 parts of raw rhizoma atractylodis macrocephalae, 9 parts of fructus chaenomelis lagenariae, 9 parts of fructus hippophae, 6 parts of lucid ganoderma, and 9 parts of radix scutellariae. The traditional Chinese medicine composition has the effect of multiple target points and multiple efficacies, and has the efficacies for whitening, moistening, removing the wrinkles, resisting the senescence, fading the spots, fadingthe scar, avoiding the face obesity, and inhibiting the excessive excretion of sebaceous gland; the traditional Chinese medicine composition has the characteristics of reasonable structure, significant efficacy and the like, and has the effect of supplementing each other; smearing is time-saving and rapid; and moreover, the combined formula can be appropriately adjusted according to different requirements of the cosmetics, and flexibility and convenience can be realized.

The invention discloses a plant stock solution having oil controlling and acne removing functions and a preparation method thereof. The plant stock solution is prepared from raw materials in percentage by weight as follows: 5%-10% of 1,3-propylene glycol, 1%-5% of glycerin, 3%-8% of plant extracts, 0.1%-1% of xanthan gum, 0.01%-0.1% of sodium hyaluronate, 0.2%-0.6% of phenoxyethanol, 0.05%-0.35% of ethylhexylglycerin and the balance of deionized water. A spiraea salicifolia extract can effectively inhibit activity of 5 alpha-reductase, inhibit secretion activity of skin glands and prevent excessive oil and acne, and a bacteriostatic component can inhibit bacteria forming acne. A lotus seed extract can effectively decompose pimple and acne and regulate oil secretion; a calendula extract has superhigh healing capacity, can calm skin and has red fading, relieving and repairing effects. The three extracts are used cooperatively to effectively control secretion of sebaceous gland, and the best use effect can be obtained.

The invention discloses a polysaccharide-containing moisturizing and oil-controlling composition and an application thereof in cosmetics. The composition is prepared from the following components in percentage by mass of 0.05 to 20% of polysaccharide moisturizing composition, 0.01%-20% of an oil control composition, 0.5%-20% of an emollient, 0.05%-10% of an emulsion stabilizer, 0.1 to 3.0% of preservative and the balance of auxiliary materials and water. The key technology of the polysaccharide-containing moisturizing and oil controlling composition is that moisturizing and oil controlling areconducted at the same time, the normal skin barrier function is restored, and the polysaccharide moisturizing composition has a good moisturizing effect; the oil control composition efficiently inhibits the activity of 5 alpha-reductase and efficiently inhibits grease and metabolites secreted by sebaceous glands, hair follicles and sweat glands of facial skin, the oil control composition not onlyinhibits the activity of the 5 alpha-reductase, but also shrinks the pore diameter and reduces the channel for grease to be secreted out of epidermis, and the oil control effect is synergistically enhanced through a physical method; and the cosmetic prepared by the invention has relatively low irritation and allergy.

Disclosed herein are topical dermal compositions comprising particles, wherein the particles comprisea) a biodegradable polymer, andb) a retinoid selected from the group consisting of:or a pharmaceutically acceptable salt thereof, wherein the particles have an average diameter between 0.1 μm and 10 μm, and wherein the variables are as defined in the specification. The compositions are useful for treating a condition associated with excess sebum production.