299 results about "Combination Product" patented technology

The invention is directed in part to oral dosage forms comprising a combination of an orally analgesically effective amount of an opioid agonist and an orally active opioid antagonist, the opioid antagonist being included in a ratio to the opioid agonist to provide a combination product which is analgesically effective when the combination is administered orally, but which is aversive in a physically dependent subject. Preferably, the amount of opioid antagonist included in the combination product provides at least a mildly negative, "aversive" experience in physically dependent addicts (e.g., precipitated abstinence syndrome).

A pharmaceutical formulation comprises a plurality of seamless minicapsules having a diameter of from 0.5 mm to 5 mm, at least some of the minicapsules containing a methyxanthine as one active ingredient, and at least some of the minicapsules containing a corticosteriod as another active ingredient.

A pharmaceutical composition in unit dose form, comprising an essentially homogeneous solution comprising a statin essentially dissolved in solvent system comprising natural or synthetic omega-3 fatty acids or pharmaceutically acceptable esters, derivatives, conjugates, precursors or salts thereof, or mixtures thereof, wherein less than 10% of the statin is undissolved in the solvent system.

The invention relates to a process for the manufacture of a pharmaceutical composition with modified release of active principle comprising at least one active principle, a lipid matrix agent composed of ester of alcohol with at least one fatty acid and at least one adjuvant.This process is characterized in that:a powder composed of at least one component selected in the group comprising the active principle and the adjuvant, is mixed, while heating and fluidizing, in order to obtain individual grains;the said lipid matrix agent is liquefied separately under warm conditions;the said powder is then coated under warm conditions by spraying the said lipid matrix agent over the individual grains;finally, the temperature of the combined product is lowered in order to allow the lipid matrix agent to solidify.

A method and composition for blood lipid therapy that comprises administering to the subject an effective amount of a PPAR agonist and / or antagonist and an omega-3 fatty acid. The methods and compositions include combination products or concomitant therapy for the treatment of subjects with hypertriglyceridemia, hypercholesteremia, mixed dyslipidemia, vascular disease, artherosclerotic disease and related conditions, obesity, the prevention or reduction of cardiovascular and vascular events, the reduction of insulin resistance, fasting glucose levels and postprandial glucose levels, and / or the reduction of incidence and / or the delay of onset of diabetes.

Provided are rapidly dissolving pharmaceutical oral dosage forms of triptans and NSAIDs, processes for the preparation thereof, and methods of treatment therewith.

A pharmaceutical combination product is disclosed that comprises a receptor tyrosine kinase inhibitor and a fatty acid synthase inhibitor, and to the use thereof in the manufacture of a medicament for use in the treatment or prophylaxis of cancer.

A Raman spectroscopy technique allows an analyte, a paramagnetic particle, and a spectral enhancement particle to combine in solution and for the combination product to be localized by a magnetic field for analysis. The spectral enhancement particle may be comprised of an active SERS metal particle with or without a material coating. The spectral enhancement particle may function as a reporter for the presence of the analyte or merely increase the magnitude of the Raman spectrum of the analyte. The technique is applicable to both immunoassays and chemical assays. Multiple spectral enhancement particle reporters may be measured in a single assay that can detect multiple analytes using the SERS effect.

Systems and methods are described for treating un-met medical needs in migraine and related conditions such as cluster headache. Included are treatments that are both rapid onset and long acting, which include sustained release formulations, and combination products. Also included are treatments for multiple symptoms of migraine, especially headache and nausea and vomiting. Systems that are self contained, portable, prefilled, and simple to self administer at the onset of a migraine attack are disclosed, and preferably include a needle-free injector and a high viscosity formulation, to eliminate such issues as fear of self administration with needles, and needle stick and cross contamination.

An environmental degradation sensor for environmentally sensitive products such as food, pharmaceuticals or cosmetic products provides the degraded state and estimated remaining life of the product. The sensor is made of a polymeric matrix and conductive filler. A control agent, selected to adjust a reaction rate of the sensor to environmental conditions, allows correlation of an electrical property of the sensor to a degraded state of the product. The sensor may be integrated with a passive RFID to provide product identification and degradation status wirelessly via reader. The sensor improves product safety, reduces cost of premature product disposal and, combined with RFIDs, improves the security of products through combined product degradation monitoring and tracking.

Blends of fertilizer granules and highly absorbent cellulosic granules carrying one or more pesticidal or other active ingredients that resist the formation of actives dust or segregation of the granules and that ensure even and efficient application of both the fertilizer and the active ingredients.

Embodiments of the invention can include systems and methods for providing a combined product for dispensing from a product dispenser. In one embodiment, a system can provide a combined product for dispensing from a product dispenser. The system can include a code generation module operable to receive data associated with a plurality of product recipes; and generate a machine readable item with a combined recipe including the plurality of product recipes, wherein the machine readable item configures a product dispenser to dispense the combined recipe.

Embodiments disclosed herein generally relate to acamprosate formulations, methods of use of the formulations, to methods of using the formulations in combination with at least one other medication, and to combination products and compositions comprising the formulations and at least one other medication, such as neuroleptic (antipsychotic) and / or antidepressant drugs.

An environmental degradation sensor for environmentally sensitive products such as food, pharmaceuticals or cosmetic products provides the degraded state and estimated remaining life of the product. The sensor is made of a polymeric matrix and conductive filler. A control agent, selected to adjust a reaction rate of the sensor to environmental conditions, allows correlation of an electrical property of the sensor to a degraded state of the product. The sensor may be integrated with a passive RFID to provide product identification and degradation status wirelessly via reader. The sensor improves product safety, reduces cost of premature product disposal and, combined with RFIDs, improves the security of products through combined product degradation monitoring and tracking.

A planting implement is configured with a cleanup system for the removal of product associated with operation of the planting implement. The planting implement generally includes a fluid pressure source in combination with at least one planting unit configured to deposit the product at a controlled rate in an agricultural field. The cleanup system generally includes a product separator with an inlet line and a collection line. The inlet line communicates the vacuum pressure generated by the pressure source to the product separator. The collection line communicates the vacuum pressure at the product separator to a location of the product on the planting implement. The vacuum pressure at the collection line is operable to entrain the product in a combined product and forced air stream that is conveyed by the collection line for removal at the product separator.

This invention relates to high organic matter plant food products for agronomic uses. Also disclosed are combination products comprising the high organic matter plant food products, articles made from and incorporating same and methods of using same in agricultural operations for restoration and / or maintenance of organic matter values and / or nutrient values in soils, particularly certified organic farm soils.

The invention relates to the field of software development process control and discloses an integrated software configuration management method based on items. The method comprises the following steps: a product is divided in a form of the module; a combination product and / or a module edition form(s) a new edition, and the new edition is corresponding to specific item set; primary code changing set produced by development is related with the items realized by the changing set; the items realized by testing codes produce a new module edition and / or a new product edition; the software is released. The method has the advantages that the software configuration management is carried out by the method and the problem that the software primary code is lack of item process knowledge is solved, thus leading the developed software primary code to be easy to manage, test and release; the development process is easy to trace back and the primary code is easy to expand and maintain, the software quality can be controlled; meanwhile, the efficiency of the software development is improved, and the development cost and the maintenance cost are reduced.

A combination product is comprised of at least one washing or cleaning composition-shaped body and at least one liquid-filled hollow body comprising one or more water-soluble or water-dispersible polymers. The combination product permits the separate formulation of liquid and solid constituents with a minimum level of packaging complexity. The solid and liquid constituents of the washing or cleaning composition can be formulated so as to be optically perceptible as separate constituents of a compact and easy-to-dose body.

A primary container (PC) cap or closure that includes a separate fastener for a separate inner container (IC). A liquid, powder or crystal is stored in the inner container ready for use. One purpose of the invention is to provide two separate containers mounted together with different ingredients for admixture at the time of use. This increases the shelf-life of the combined products.

A composition, method and kit comprising a compound for the inhibition of the binding of α4β1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin and other therapeutic compounds for the control or prevention of diseases states in which α4β1 is involved.

The invention discloses an intelligent cooking method and an intelligent cooking type pot and stove combination product. The intelligent cooking method comprises the following steps that the user input is received so as to determine a preset dish, and an intelligent menu is read according to the preset dish; if the preset dish is read from the intelligent menu, an intelligent stove is controlled to adjust the gas flow according to a corresponding relationship between the cooking time and the temperature, and a user is reminded to execute corresponding cooking operation according to the corresponding relationship between the cooking time and the cooking operation instruction; if the preset dish is not read from the intelligent menu,, temperature information of a temperature control pot is collected after an collection instruction is received; the temperature information and the collection time are subjected to polynomial fitting so as to obtain the corresponding relationship between thecooking time and the temperature; and the cooking operation instruction input by the user is received, and the instruction receiving time and the cooking operation instruction are stored in an associative mode as the corresponding relationship between the cooking time and the cooking operation instruction. According to the intelligent cooking method and the intelligent cooking type pot and stovecombination product, the temperature and cooking operation information of each time node in cooking are recorded so as to form the intelligent menu, in the follow-up cooking process, the cooking duration and degree are controlled and the cooking operation of the user is guided according to the intelligent menu, and therefore the problems that the user cannot do the cooking and cannot do the cooking well can be solved.

There is provided combination products comprising (a) a mast cell inhibitor, or a pharmaceutically-acceptable salt or solvate thereof; and (b) a PPARY agonist, or a pharmaceutically-acceptable salt or solvate thereof. Such combination products find particular utility in atherosclerosis and related conditions.

A method of treating a disease state or condition in humans via topical brainstem afferent stimulation therapy via the administration of a cannabinoid drug(s) and a second therapeutically active agent(s) to the back of the neck of a human patient to provide regional neuro-affective therapy is disclosed. In certain preferred embodiments, the cannabinoid drug(s) are not psychoactive or substantially not psychoactive. In certain embodiments, the drugs are incorporated into a pharmaceutically acceptable topical carrier, e.g., a cream. In certain preferred embodiments, the cannabinoid drug(s) comprises cannabidiol.

Combinations of one or more dihydropyridine calcium channel blockers with mixtures of omega-3 fatty acids, methods of administering such combinations, and unit dosages of such combinations.

Osteoporosis and the like metabolic bone diseases have a high frequency of causing lumbago and the like pains and bone fracture, due to lowering of the bone strength caused by the reduction of bone mass. Accordingly, great concern has been directed toward the creation of a drug which can increase the bone mass and bone strength by controlling the whole bone metabolism. The pharmaceutical composition or combination product of the invention comprising a non-living body-derived non-peptide osteoblast differentiation promoting compound and a bisphosphonate having a bone resorption inhibitory action is useful as a bone mass increasing inducer which can increase the bone mass and / or bone strength by controlling the bone metabolism.

This invention provides methods and pharmaceutical compositions / therapy combination product for cancer treatment and / or augmenting the effectiveness of cancer chemotherapeutic agents by use of a combination of ascorbic acid and vitamin K3.

Embodiments of the invention can include systems and methods for providing a promotion for a combined product dispensed from a product dispenser. In one embodiment, a system can provide a promotion for a combined product dispensed from a product dispenser. The system can include a code generation module operable to receive data associated with a plurality of product recipes; and generate a machine readable item with a promotion identifier, and a combined recipe including the plurality of product recipes, wherein the machine readable item configures a product dispenser to promote and dispense the combined recipe.

A primary container (PC) cap or closure that includes a separate fastener for a separate inner container (IC). A liquid, powder or crystal is stored in the inner container ready for use. One purpose of the invention is to provide two separate containers mounted together with different ingredients for admixture at the time of use. This increases the shelf-life of the combined products.