37results about How to "Longer effect" patented technology

According to some embodiments, a microdermabrasion device for treating skin comprises a handpiece assembly having a distal end and a proximal end. The handpiece assembly includes at least one delivery conduit and at least one waste conduit. The microdermabrasion device additionally comprises a tip configured to be positioned along the distal end of the handpiece assembly, wherein the tip is adapted to contact skin surface. In several embodiments, the tip comprises a lip, a first opening in fluid communication with the fluid delivery conduit and a second opening in fluid communication with the waste conduit. In one embodiment, the device includes one or more abrasive elements positioned along a distal end of the tip, wherein the abrasive elements are configured to selectively remove skin as the tip is moved relative to a skin surface. In some embodiments, the delivery conduit is configured to selectively deliver at least one time-release material to the skin surface being treated.

According to some embodiments, a microdermabrasion device for treating skin comprises a handpiece assembly having a distal end and a proximal end. The handpiece assembly includes at least one delivery conduit and at least one waste conduit. The microdermabrasion device additionally comprises a tip configured to be positioned along the distal end of the handpiece assembly, wherein the tip is adapted to contact skin surface. In several embodiments, the tip comprises a lip, a first opening in fluid communication with the fluid delivery conduit and a second opening in fluid communication with the waste conduit. In one embodiment, the device includes one or more abrasive elements positioned along a distal end of the tip, wherein the abrasive elements are configured to selectively remove skin as the tip is moved relative to a skin surface.

According to some embodiments, a method of treating a skin surface of a subject comprises heating a skin surface, abrading native skin tissue of a subject using a microdermabrasion device, wherein using the microdermabrasion device comprises moving the microdermabrasion device relative to the skin surface while simultaneously delivering at least one treatment fluid to the skin surface being treated and cooling the abraded skin surface.

The present invention relates to methods and compositions for treating neuropathic pain and neuropsychiatric disorders by administering agents that are effective in reducing the effective amount, inactivating, and / or inhibiting the activity of a Na+—K+-2Cl− (NKCC) cotransporter. In certain embodiments, the Na+—K+-2Cl− co-transporter is NKCC1.

A soot preventing type tail trim may include a tail pipe discharging exhaust gas, and a body enclosing an outer circumference of the tail pipe with a predetermined space therebetween, such that wind may be allowed to flow into the predetermined space and to be discharged therefrom to generate a separation layer in the exhaust gas passing the tail pipe by the wind.

According to some embodiments, a method of treating a skin surface of a subject comprises heating a skin surface, abrading native skin tissue of a subject using a microdermabrasion device, wherein using the microdermabrasion device comprises moving the microdermabrasion device relative to the skin surface while simultaneously delivering at least one treatment fluid to the skin surface being treated and cooling the abraded skin surface.

A porous cellulose aggregate characterized by having a secondary aggregate structure resulting from aggregation of primary cellulose particles, having a pore volume within a particle of 0.265 to 2.625 cm3 / g, containing I-type crystals and having an average particle size of over 30 to 250 μm, a specific surface area of 0.1 to less than 20 m2 / g, a repose angle of 25° to less than 44° and a swelling degree of 5% or more, and characterized by having the property of disintegrating in water.

A rolling device in which damage such as seizure or wear is less liable to occur and which has a long life, even when used under severe conditions such as high speed, heavy load, high temperature and insufficient lubrication. A thrust needle roller bearing includes an inner ring 1, outer ring 2, and a plurality of rolling elements 3 rollably arranged between a raceway surface 1a of inner ring 1 and a raceway surface 2a of outer ring 2. A lubricant film consisting of a solid lubricant is coated over an area equivalent to an area ratio of 75% or more of at least one member of the group consisting of raceway surface 1a of inner ring 1, raceway surface 2a of outer ring 2, and a rolling contact surface 3a of rolling element 3. The thickness of the lubricant film is preferably 0.05 μm or more and 8 μm or less.

Systems and methods are described for treating un-met medical needs in migraine and related conditions such as cluster headache. Included are treatments that are both rapid onset and long acting, which include sustained release formulations, and combination products. Also included are treatments for multiple symptoms of migraine, especially headache and nausea and vomiting. Systems that are self contained, portable, prefilled, and simple to self administer at the onset of a migraine attack are disclosed, and preferably include a needle-free injector and a high viscosity formulation, to eliminate such issues as fear of self administration with needles, and needle stick and cross contamination.

The present invention is directed to methods and compositions for treating pulmonary disease comprising delivering directly to a patient's lungs a therapeutically effective amount of oxybutynin in combination with one or more pharmaceutically effective agents. Oxybutynin may be selected from the group consisting of, but not limited to, a xinafoate salt, a palmitate salt, a pamoic salt, a resonate salt, a laurate salt and other salts. The pharmaceutically effective agents comprise bronchodilators, antiinflammatories, corticosteroids, corticosteroid reversal agent or alveolar growth agents or other agents selected from proteinase or protease inhibitors.

According to the present invention, there is provided a negative electrode material for a lithium secondary battery, including a negative electrode active material including a carbon material and having an ID / IG ratio of XPS of 0.2 to 0.74, and a coating portion disposed on a surface of the negative electrode active material. The coating portion has a boron atom and a crosslinking site having a bonding portion of C—O—C and interposed between the boron atom and the negative electrode active material. In an XPS spectrum, when an area of the peak of the 1s electron orbital of the boron atom is denoted by Ab and an area of the peak of the C—O—C bonding portion is denoted by Ac, the ratio Ac / Ab of the peak area Ac to the peak area Ab is 0.11 or more and 0.51 or less.

Administration of Oxybutynin directly to a patient's lungs for treating urinary incontinence, respiratory disease or IBD.