Method for forming, by means of an inversion technique, a model of an underground zone, constrained by static data: data obtained by seismic exploration or measured in situ (logs), and by dynamic data: production measurement, well testing, etc. From an a priori selected meshed geologic model and from relations between parameters or physical quantities characteristic of the medium: acoustic impedance and cabsolute permeability for example, a simultaneous inversion of the two parameters is performed by minimizing a global cost function, which has the effect of considerably decreasing the number of possible solutions and of improving characterization of the underground zone. The method can be used notably for modelling hydrocarbon reservoirs, of zones likely to be used as gas, waste storage places, etc.