1102results about How to "Optimization range" patented technology

Methods for producing modified polypeptides containing amino acid analogues are disclosed. The invention further provides purified dihydrofolate reductase polypeptides, produced by the methods of the invention, in which the methionine residues have been replaced with homoallyglycine, homoproparglycine, norvaline, norleucine, cis-crotylglycine, trans-crotylglycine, 2-aminoheptanoic acid, 2-butynylglycine and allylglycine.

Embodiments of the invention are concerned with scheduling resources to perform tasks requiring a plurality of capabilities or capabilities and capacities, and has particular application to highly changeable or uncertain environments in which the status and the composition of tasks and / or resources changes frequently. Embodiments provide a method for use in a scheduling process for scheduling allocation of resources to a task, each resource having a plurality of attributes, wherein the task has one or more operational constraints including a required plurality of capabilities, and a performance condition associated therewith. The method comprises: receiving data indicative of a change to the status of the scheduling process; in response to receipt of the status data, reviewing the attributes of individual resources so as to identify combinations of resources able to collectively satisfy said capability requirements of the task; evaluating each identified combination of resources in accordance with a performance algorithm so as to identify an associated performance cost; selecting a combination of resources whose identified performance cost meets the performance condition; and scheduling said task on the basis of said selected combination of resources. In embodiments of this aspect of the invention, changes to resource configurations are effected as part of the scheduling process. These changes can be made dynamically, in response to the occurrence of events that have a bearing on the scheduling process, and involve aggregating resources together so as to create, essentially, a new resource pool from which selection can be made.

Methods for producing modified polypeptides containing amino acid analogues are disclosed. The invention further provides purified dihydrofolate reductase polypeptides, produced by the methods of the invention, in which the methionine residues have been replaced with homoallyglycine, homoproparglycine, norvaline, norleucine, cis-crotylglycine, trans-crotylglycine, 2-aminoheptanoic acid, 2-butynylglycine and allylglycine.

Reactive sensors typically exhibit nonlinear response to the combination of an excitational signal (e.g., sinusoidally oscillating signal) and a physical parameter under measure (e.g., position of magnetic core member). Such sensors are typically sensitive to temperature variation. Systems and methods are disclosed for compensating for the nonlinear and / or temperature dependant behavior of reactive sensors and for calibrating the post-compensation output signals relative to known samples of the physical parameter under measure (e.g., position). One class of embodiments comprises a housing containing at least part of a reactive sensor, a monolithic integrated circuit and a timing reference (e.g., an oscillator crystal). The integrated circuit includes a waveform generator for generating a sensor exciting signal, a detector for detecting the response of the sensor to the combination of the exciting signal and the under-measure physical parameter, a temperature compensating unit and a Pade' Approximant based, nonlinearity compensating unit. The temperature compensating unit and the Pade' Approximant nonlinearity compensating unit are tuned by use of digitally programmed coefficients. The coefficients calibrate the final output as well as compensating for nonlinearity and temperature sensitivity. A highly accurate measurement of the under-measure physical parameter is made possible even though each of the sensor and compensating circuitry may be relatively simple, compact, and low in cost.

The present invention relates to the field glycosylation engineering of proteins. More particular, the present invention is directed to the glycosylation engineering of proteins to provide proteins with improved therapeutic properties, e.g., antibodies, antibody fragments, or a fusion protein that includes a region equivalent to the Fc region of an immunoglobulin, with enhanced Fc-mediated cellular cytotoxicity.

The present invention relates to a wireless transmitter comprising a transmitter radio unit working a wireless transmitter comprising a transmitter radio unit working in the millimeter wave frequency band using a directional antenna and a bidirectional radio unit working in a frequency range different from said transmitter radio unit and using an omnidirectional antenna. The invention further relates to a wireless receiver and a wireless relay.

New low-cost CO2 sorbents are provided that can be used in large-scale gas-solid processes. A new method is provided for making these sorbents that involves treating substrates with an amine and / or an ether so that the amine and / or ether comprise at least 50 wt. percent of the sorbent. The sorbent acts by capturing compounds contained in gaseous fluids via chemisorption and / or physisorption between the unit layers of the substrate's lattice where the polar amine liquids and solids and / or polar ether liquids and solids are located. The method eliminates the need for high surface area supports and polymeric materials for the preparation of CO2 capture systems, and provides sorbents with absorption capabilities that are independent of the sorbents' surface areas. The sorbents can be regenerated by heating at temperatures in excess of 35° C.

A system and method for real-time multi-view (i.e. not just frontal view) face detection. The system and method uses a sequence of detectors of increasing complexity and face / non-face discriminating thresholds to quickly discard non-faces at the earliest stage possible, thus saving much computation compared to prior art systems. The detector-pyramid architecture for multi-view face detection uses a coarse-to-fine and simple-to-complex scheme. This architecture solves the problem of lengthy processing that precludes real-time face detection effectively and efficiently by discarding most of non-face sub-windows using the simplest possible features at the earliest possible stage. This leads to the first real-time multi-view face detection system which has the accuracy almost as good as the state-of-the-art system yet 270 times faster, allowing real-time performance.

In a wireless LAN (WLAN) a method and system for dynamically assigning a configuration identity to a device being connected to the WLAN is provided. An access point (AP) or other device is plugged into a switch port of an Ethernet switch, and discovers its location and the location of a WLAN management module. The device can then request its configuration identity from the WLAN management module by providing its switch and / or port location. When a device in the WLAN needs to be replaced, the method and system enable dynamic assignment of configuration identity for the new device, to ensure that the configuration and identity of the new device matches that of the device it is replacing.

The systems and methods described herein include hexapod systems, Stewart platform systems and other mechanical movement systems, in which a set of independently moveable trucks support legs that couple to a working surface capable of holding a machine tool or other end-effector, and preferably wherein the trucks travel across a reference surface, such as around the circumference of a circle or along some other pre-defined geometrical pattern or track. For example, as described herein, the systems include Stewart platform machines that have six supportive legs each of which connects to a truck that can travel independently along a track. By coordinating the movement of these six trucks, the working surface can be moved in three dimensional space and can be oriented about three axes, providing control of roll, pitch and yaw.

Signal detection and recognition employees coordinated illumination and capture of images under to facilitate extraction of a signal of interest. Pulsed illumination of different colors facilitates extraction of signals from color channels, as well as improved signal to noise ratio by combining signals of different color channels. The successive pulsing of different color illumination appears white to the user, yet facilitates signal detection, even for lower cost monochrome sensors, as in barcode scanning and other automatic identification equipment.

A system and method for encoding and decoding information by use of radio frequency antennas. The system includes one or more interrogator devices and RFID data tags. The RFID data tags include a plurality of antenna elements which are formed on a substrate or directly on an object. The antenna elements are oriented and have dimensions to provide polarization and phase information, whereby this information represents the encoded information on the RFID tag. The interrogator device scans an area and uses radar imaging technology to create an image of a scanned area. The device receives re-radiated RF signals from the antenna elements on the data tags, whereby the data tags are preferably represented on the image. The re-radiated RF signals preferably include polarization and phase information of each antenna element, whereby the information is utilized using radar signal imaging algorithms to decode the information on the RF data tag.

An electric arc welding system for creating an AC welding arc between an electrode and a workpiece wherein the system comprises a first controller for a first power supply to cause the first power supply to create an AC current between the electrode and workpiece by generating a switch signal or command with polarity reversing switching points in the first controller, with the first controller operated at first welding parameters in response to first power supply specific parameter signals to the first controller. The system has at least one slave controller for operating a slave power supply to create an AC current between the electrode and workpiece by reversing polarity of the AC current at switching points where the slave controller is operated at second welding parameters in response to second power supply specific parameter signals to the slave controller. An information network connected to the first controller and the slave controller and containing digital first and second power supply specific parameter signals for the first controller and the slave controller and a digital interface connects the first controller with the slave controller to control the switching points of said second power supply by the switch signal or command from the first controller.

Embodiments of the invention may include a sensor system and a method used to track the behaviors of targets in an area under surveillance. The invention may include a sensor array located in the area that is capable of sending messages to a user when behavior of a tracked target is determined to be anomalous. In making the determination of anomalous behavior, the sensor system and method may generate and continuously refine a pattern of life model that may examine, for example, the paths a target may take within the sensor array and the end points of the paths taken. The sensor system and method may also incorporate any user defined conditions for anomalous behavior.

Methods for carrying out high temperature reactions such as biomass pyrolysis or gasification using solar energy. The biomass particles are rapidly heated in a solar thermal entrainment reactor. The residence time of the particles in the reactor can be 5 seconds or less. The biomass particles may be directly or indirectly heated depending on the reactor design. Metal oxide particles can be fed into the reactor concurrently with the biomass particles, allowing carbothermic reduction of the metal oxide particles by biomass pyrolysis products. The reduced metal oxide particles can be reacted with steam to produce hydrogen in a subsequent process step.

A birefringent interferometer system is described which uses nematic liquid crystal cells to produce variable optical path differences (OPD) between light of different polarization states that are interfered at a polarizing analyzer. Fixed retarders may also be incorporated to extend the range of OPD. The interferometer provides wide field-of-view, continuously variable path difference over a large range, and an on-board monitor of OPD for ensuring accurate settings of path difference, and hence, an accurate wavelength scale in the spectra produced by the apparatus. The system can further incorporate additional polarizing optics so it responds equally well to light of any incident polarization state without loss of efficiency.

A collision detection and path prediction system (10) adapted for use with a traveling host vehicle (12) having an operator, includes a locator device (20) configured to determine the current position coordinates, and pluralities of trail and immediate dynamic path coordinates of the vehicle (12) and a communicatively coupled traveling remote vehicle (16). The system further includes a preferred controller (36) configured to predict a collision between the two vehicles (12,16) from the coordinates, and determine a plurality of projected path coordinates for the host vehicle (12) relative to the remote vehicle (16) trail coordinates.

A crank device comprising foot supports with means for controlling stability and angle relative to the motion. There are linkages for stabilising and keeping a correct angle relative to an apparatus frame during a full rotation. The foot supporting means have also means for adjusting the angle to create a toe-heel tilt. The foot supporting means in form of platforms have optional tilt movement with an adjustable mechanism, the movement transverse the stepping motion, for utilising proprioseptive training and exercise.

An apparatus and method for providing electrical energy to an electrical device by deriving the electrical energy from motion of the device. In one embodiment, the inventive apparatus includes a novel kinetic electrical power generator (KEPG) consisting of an inventive oscillating weight having an internal cavity with a freely movable acceleration element disposed therein, resulting in improved acceleration and oscillation capabilities and lower motion threshold for the weight, a system for converting the weight's oscillating motion into rotational motion, and an electromechanical transducer system for generating electrical energy from the rotational motion. The novel KEPG includes components for modifying the electrical energy for storing and / or feeding the modified electrical energy to the electrical device. Optional components may be included for using the modified electrical energy to recharge one or more rechargeable batteries used in an electric device. Alternate advantageous embodiments of the inventive apparatus include, but are not limited to: a KEPG with multiple inventive oscillating weights to increase velocity and frequency of desirable rotational motion, and a KEPG system utilizing multiple electrically coupled KEPG sub-systems.

An image pickup optical lens assembly, sequentially arranged from an object side to an image side along an optical axis, comprising: the first lens element with positive refractive power having a convex object-side surface, the second lens element with negative refractive power, the third lens element with refractive power, the fourth lens element with positive or negative refractive power having a concave object-side surface and a convex image-side surface with both being aspheric, and the fifth lens element with positive or negative refractive power having a convex object-side surface and a concave image-side surface with both being aspheric. Additionally, the image pickup optical lens assembly satisfies conditions related to the reduction of the total length and the sensitivity of the image pickup optical lens assembly for compact cameras and mobile phones with camera functionalities.

Electric aircraft, including in-flight rechargeable electric aircraft, and methods of operating electric aircraft, including methods for recharging electric aircraft in-flight, through the use of unmanned aerial vehicle (UAV) packs flying independent of and in proximity to the electric aircraft.

Time-of-flight (TOF) phase-derived data is dealiased by operating the TOF system using at least two close-together modulation frequencies f1 and f2 that are close to the TOF system maximum modulation frequency fm. On one hand, phase data acquired by the TOF is associated with a desirably long aliasing interval range ZAIR normally associated with a rather low modulation frequency. On the other hand, phase data acquired by the TOF system is also associated with the high precision certainty as to Z value normally associated with high modulation frequency. Preferably the TOF system operates always close to fm such that TOF operating efficiency is high, and system signal / noise ratio is not substantially degraded using the present invention.

An electronically controlled suspension system for a bicycle includes at least one spring element between first and second parts the bicycle, both parts being movably interconnected. At least one parameter of the spring element is modified. At least one actuator influences the spring element to modify the at least one parameter. An electronic module produces a control signal for the at least one actuator. A control device is influenced by the control signal produced by the electronic module. The control device is connected to at least one of the electronic module and the actuator through a radio signal. A corresponding method controls the suspension system for the bicycle and a computer program executes the method.

A resonator device includes a piezoelectric resonator having a detuning layer sequence arranged on the piezoelectric resonator. The detuning layer sequence includes at least a first layer having a high acoustic impedance and a second layer having a low acoustic impedance.

A system, method and program product for monitoring a complex signal for ultrasensitive detection of state changes, or for signature recognition and classification is provided. A complex signal is decomposed periodically for empirical modeling. Wavelet analysis, frequency band filtering or other methods may be used to decompose the complex signal into components. A library of signature data may be referenced for selection of a recognized signature in the decomposed complex signal. The recognized signature may indicate data being carried in the complex signal. Estimated signal data may be generated for determination of an operational state of a monitored process or machine using a statistical hypothesis test with reference to the decomposed input signal.

A method of terrain mapping and / or obstacle detection for aircraft, comprising: (a) transmitting a non-scanning beam that illuminates the terrain and / or obstacles; (b) receiving a Doppler shifted signal that is Doppler frequency shifted by an amount dependent on an angle between a line of flight of the aircraft and scatterers that reflect the transmitted beam; (c) determining the angle from the Doppler frequency; (d) determining the range of at least some of said scatterers; and (e) determining the azimuth and elevation of the scatterers.

A wireless identification device including a housing; circuitry in the housing configured to provide a signal to identify the device in response to an interrogation signal; and a selectively actuated switch supported by the housing and controlling whether the circuitry identifies the device. A method of manufacturing a wireless identification device, the method comprising configuring circuitry to provide a signal to identify the device in response to an interrogation signal; coupling the circuitry to a push-on / push-off switch supported by the housing and controlling whether the circuitry provides the signal to identify the device; and encasing the circuitry in a housing such that the switch is actable from outside the housing by touching a portion of the housing.

Devices, systems and methods for use in separating sample materials into different sample components and then isolating one or more of the sample components for further processing or analysis are disclosed. Devices employ configurations that optionally allow a sample material to be electrophoretically separated into sample components in a separation matrix within a separation conduit. The sample components may then be detected in a detection zone in the separation conduit, and then selected components shunted to a component collection conduit within the device downstream of the detection zone for further processing or analysis based on information received at the detection zone. Methods of using these devices, and systems that incorporate these devices are also envisioned.

An exercise device having many advantageous features is described, including the ability to provide a variety of different accessory grips to the user, and the ability to easily mount the device to a wall. One exercise device described is an inelastic resistance device having integral hand grips. The accessory grips are removably attachable to the integral grip of an exercising device, and provide for gripping by the hands, foot or other body parts. The selection of a specific accessory grip allows the user to exercise by specific body parts and provides for a greater number of possible exercises. Accessory grips are attachable to the integral grips, greatly adding to the flexibility of the device. In addition, a novel hand grip is described having a plurality of cords that can be selected for gripping, and a bracket for mounting a door jamb mountable exercise device to a wall is described.