The invention discloses a treatment system for homogenization of a solid medium formula and a method therefor. The system is applied to cement grouting fixation for medium- and low-radioactive wastesin nuclear industry. The system includes a cement metering and storing system, a water metering system, and additive metering and storage system, a mixing bin, a stirring system and a pumping system.The method includes the steps of: 1) according to formula demand of cement fixation of a nuclear power plant, feeding a cement dry material to a first-stage stirring bin according to preset quantity via a dry material storage bin; 2) according to the formula demand, feeding a liquid component to the mixing bin to initially mix the components in the mixing bin, and feeding the mixture to the first-stage stirring bin; 3) at the same time, performing initial stirring to the cement dry material, an additive and water in the first-stage stirring bin, thus preparing a mixture body; 4) after the initial stirring is completed, feeding the mixture body into a secondary initial bin to perform fine stirring; 5) after the secondary stirring is completed, feeding the mixture body to a cement grouting station through the pumping system. The treatment system and the method are different from systems and methods applied generally in nuclear power plants, wherein secondary stirring is designed, so thatmaterials are stirred more homogeneously.