71 results about "Arterial stents" patented technology

A blood flow sensing system is disclosed, including a sensor coupled to an antenna, such that the sensor measures a flow of blood within a blood vessel when stimulated with a short range radio frequency energy field detectable by the antenna. Such a system additionally can include a transmitter and receiver unit (i.e., a transmitter / receiver), which can transmit the short range radio frequency energy field to the antenna of the sensor. The transmitter and receiver unit can also receive data transmitted from the sensor via the antenna. Such a system additionally includes a stent integrated with sensor, wherein the stent comprises a small diameter cylinder that props open a blood vessel and wherein the stent is moveable into the blood vessel to form a rigid support for holding the blood vessel open in order to measure the flow of blood within the blood vessel.

The invention relates to a percutaneous aorta bracket or an aortic valve bracket system with far-end protection, which comprises an outer sheath pipe, a limit pipe and an inner sheath pipe, wherein the inner sheath pipe is arranged in the limit pipe; the limit pipe is arranged in the outer sheath pipe; the inner sheath pipe is a hollow pipe; three handles are respectively arranged at the near ends of the inner sheath pipe, the limit pipe and the outer sheath pipe. The system further comprises a protector and a protector limiting device, wherein the protector is arranged between the far end parts of the outer sheath pipe and the inner sheath pipe; the near end of the protector is connected with the far end of the protector limiting device; the protector limiting device is arranged between the limit pipe and the outer sheath pipe; the near end of the protector limiting device is fixedly connected with the far end of the limit pipe; a retracing conducting wire is fixedly connected with the near end of the protector; the far end part of the end retracing conducting wire is arranged on the outer side of the outer sheath pipe. The system provided by the invention effectively prevents impurities such as valve leaflet tissue or atheromatous plaque touched to fall due to follow-up operations from entering into vessels such as carotid, remarkably reduces the complexity and the difficulty of the operation, and shortens the operation time and the recovery time after the operation.

The invention provides a negative-Poisson-ratio chiral concave hexagonal hybrid unit cell vascular stent which comprises an annular angular point and three ligaments, and the three ligaments are at equal intervals and are tangent to the annular angular point to form single angular points. Mirroring operation is carried out on the single angular points to form chiral concave hexagonal hybrid periodic unit cells. The chiral concave hexagonal hybrid periodic unit cells are annularly and periodically arranged along an arterial stent and periodically arranged along the arterial stent in a mirroringmode to form the chiral concave hexagonal hybrid unit cell vascular stent. The stent has the negative Poisson ratio characteristic, the mechanical property of the vascular wall internal membrane canbe matched through unit cell structure parameter regulation and control, the damage of the stent to vascular wall biological tissue is reduced, the restenosis risk of the vascular wall is reduced, andvascular wall biological tissue regeneration is promoted.

Methods of treating renal cancers and other kidney-related inflammatory disorders with a bioabsorbable polymer scaffold (such as a stent) are described. The treatments are provided as alternative to complete or partial surgical removal of a diseased kidney.

The invention relates to the field of coronary stents, specifically to a method for reducing the incidence of in-stent restenosis and its special stainless steel material. The method of the invention adds a proper amount of copper element (2.0-6.0% by weight) into the common clinical coronary stent material 316L stainless steel, and conducts special heat treatment so as to make the copper separated in a copper-rich phase out of the stainless steel substrate. The stent is enabled to continuously release trace amounts of copper ions in a clinical environment, and the coronary stent is endowed with an anti-restenotic function, thus effectively reducing the incidence of restenosis after stent implantation. With a unique function of reducing the in-stent restenosis phenomenon caused by stent implantation into a coronary artery, the 316L type copper-containing stainless steel of the invention is conducive to solve clinical problems such as high incidence of in-stent restenosis after implantation of existing stainless steel coronary stents, and can be applied in coronary stents and other clinical medicine fields, thus providing a new idea and material basis for development and application of coronary stents.

A coronary stent is provided with asymmetric drug releasing controlled coating used in interventional therapy of coronary disease, containing a bare stent and a coating consisting of drug and carrier, the coating is coated onto the outer wall surface of the bare stent, and is multi-layered. The drug concentration in the coating increases in sequence from the outer layer to the inner layer. The drugs used in different layers of the coating may be identical or different, and particularly may be one or more selected from taxol, rapamycin, heparin, docetaxel and a combination thereof. The carrier may be a random (lactide-glycolide) copolymer having a molecular weight of 50,000-200,000. The drug-coated stent of the present invention employs highly effective drugs, enabling a thinnest coating and reducing the vascular irritation. The drug release is regulated by altering the coating manner so as to satisfy the clinical requirement for controlled drug release. The employed asymmetric coating promotes regenerative repairing of vascular endothelium. The present invention is a drug-coated coronary stent with reasonable design, with the coating capable of effectively preventing vascular restenosis and reducing occurrence of late thrombosis.

The invention relates to a surgical instrument table used for containing an arterial stent conveying system when a doctor carries out preparation work before surgery. The surgical instrument table is characterized by comprising a table face, a first shielding device, a frame body, a control portion and a movable portion. The first shielding device is connected with the table face and surrounds the edges of two wide sides of the table face and the edge of one long side of the table face. The frame body is used for supporting the table face and is provided with a telescopic stand column. The control portion is provided with a displayer and a control chip and is used for controlling the length of stretching and retraction of the telescopic stand column. The movable portion is connected to the bottom of the frame body. The height of the surgical instrument table can be adjusted according to the height of the doctor, and therefore the doctor can carry out surgical operations more comfortably.

The invention discloses a vertebral artery stent. The vertebral artery stent comprises denser class-I annular units and sparser class-II annular units, which are connected and respectively arranged at the near end and the far end of a vertebral artery to form a tubular structure, wherein each denser class-I annular unit is formed by tandem connection of axially symmetrical U-shaped structures, and each sparser class-II annular unit is formed by tandem connection of axially asymmetrical U-shaped structures. Through the approach, the vertebral artery stent can effectively reduce the incidence of restenosis, provides a good platform for the development of vertebral artery stents, and can realize the purpose of treatment of the starting place of stenosis so as to meet the requirements on vertebral artery stenosis in clinic.

The invention provides an ascending aorta repair stent anchored by innominate artery, comprising an ascending aorta stent segment and an innominate artery stent segment, wherein an innominate artery portion of the stent is first released and a body portion is then released; the distal end opening of the body portion facing the distal end of the aortic arch lumen, and the body portion of the stentcovers the dissection at the primary rupture of the ascending aorta. When the release is completed, the main body terminates above the junction of the sinus canal. The longitudinal beam structure is made of a temperature-dependent shape memory metal material extending to the great curvature side of the aortic arch of the innominate artery and to the minor curvature side of the aortic arch, and isreleased so as to satisfy the individualized ascending aortic anatomical arc of different patients to abut against the aortic wall. The stent is anchored only according to the special anatomical shapeof the ascending aorta and the innominate artery and the memory metal longitudinal beam structure. Used in patients with type A aortic dissection in the acute phase of surgical contraindication whenwaiting for the transitional phase of surgery for patients with high surgical risk of acute type A aortic dissection to provide follow-up surgical treatment opportunities.

The invention relates to the field of coronary stents, specifically to a method for reducing the incidence of in-stent restenosis and its special stainless steel material. The method of the invention adds a proper amount of copper element (2.0-6.0% by weight) into the common clinical coronary stent material 316L stainless steel, and conducts special heat treatment so as to make the copper separated in a copper-rich phase out of the stainless steel substrate. The stent is enabled to continuously release trace amounts of copper ions in a clinical environment, and the coronary stent is endowed with an anti-restenotic function, thus effectively reducing the incidence of restenosis after stent implantation. With a unique function of reducing the in-stent restenosis phenomenon caused by stent implantation into a coronary artery, the 316L type copper-containing stainless steel of the invention is conducive to solve clinical problems such as high incidence of in-stent restenosis after implantation of existing stainless steel coronary stents, and can be applied in coronary stents and other clinical medicine fields, thus providing a new idea and material basis for development and application of coronary stents.

An improved aortic arch stent graft blood vessel includes an aortic stent blood vessel and three branch arterial stent blood vessels, wherein the aortic stent blood vessel is in a pre-curved shape andcomprises a heart-proximal-end segment, a recessed portion and a heart-distal-end segment. The recessed portion comprises a first step and a second step. The heart-proximal-end segment has an opening1 on the upper middle portion of its right sidewall. An opening 2 is disposed on the right side of the first step. An opening 3 is disposed on the upper middle portion of the left sidewall of the heart-distal-end segment. Inner chimney brackets 1, 2, and 3 are fixed to the openings 1, 2 and 3 respectively. The three branch arterial stent blood vessels are disposed in the three inner chimney brackets respectively. The improved aortic arch stent graft blood vessel can prevent the mutual interference between the two inner chimney brackets at the heart-proximal end when compressed, so that the aortic stent blood vessel is easy to be compressed and placed into a small-diameter delivery system, and a guide wire and a catheter are likely to select respective inner chimney brackets.

An improved aortic arch stent graft blood vessel includes an aortic stent blood vessel and three branch arterial stent blood vessels, wherein the aortic stent blood vessel is an approximately arc multi-segment structure formed by splicing a heart-proximal-end segment, a recessed segment and a heart-distal-end segment. The heart-proximal-end segment has an opening 1. An opening 2 is formed in the top wall of the recessed segment. An opening 3 is disposed in the heart-distal-end segment. Inner chimney brackets 1, 2, and 3 are fixed to the openings 1, 2 and 3 respectively. The three inner chimneybrackets are staggered in the axial direction. The three branch arterial stent blood vessels are disposed in the three inner chimney brackets respectively. The improved aortic arch stent graft bloodvessel can prevent the mutual interference between the two inner chimney brackets at the heart-proximal end when compressed, so that the aortic stent blood vessel is easy to be compressed and placed into a small-diameter delivery system, and a guide wire and a catheter are likely to select respective inner chimney brackets, so as to facilitate the delivery and the release of the branch arterial stent blood vessels.

The invention provides an aortic root stent system. The aortic root stent system comprises an aortic stent and a sinus anchoring stent, wherein the aortic stent is correspondingly arranged on the inner wall of the ascending aorta; the sinus anchoring stent is attached to the inner wall of the aortic sinus and extends downwards from the junction of sinus canals; the bottom of the sinus anchoring stent extends inwards to form a plurality of crown valve stents attached to the aortic sinus; the peripheral surfaces of the crown valve stents form a garlic-clove-shaped structure; the top ends of theinner sides of the crown valve stents correspondingly extend to the outer side of the valve ring; and an opening allowing valve leaflets to move freely is formed in the tail end of each crown valve stent. For the aortic root stent system, the crown valve stents can increase the anchoring area of the whole sinus anchoring stent in the aortic valve, the positioning is firm, displacement seldom occurs under the impact of blood flow, and thus the stability of the aortic root anchoring system in the aortic valve is improved.

The invention discloses functions and application of responsive to centrifugal force and shear stress gene 1 (RECS1) to treatment of restenosis after vascular injury. An RECS1 knockout mouse and a wild type mouse are taken as experimental subjects, and detection on mouse internal membrane regeneration, vessel wall cell proliferation level and smooth muscle cell phenotype transformation is carried out by a vascular injury model. Detection results prove that by virtue of RECS1 knockout, internal membrane regeneration and cell proliferation can be obviously inhibited, and smooth muscle cells are inhibited to be transformed into synthetic phenotype from contractile phenotype. Therefore, the functions of the RECS1 to the restenosis after vascular injury are mainly embodied in that internal membrane regeneration, cell proliferation and smooth muscle cell phenotype transformation are promoted by the RECS1. Aiming at the functions of the RECS1, the RECS1 can be used as a drug target for screening medicines for preventing, relieving and / or treating the disease of restenosis after vascular injury; an inhibitor of the RECS1 can be used for preparing medicines and arterial stents for preventing, relieving and / or treating the restenosis after vascular injury.

The invention relates to the technical field of medical appliances and discloses a pulmonary artery support. The pulmonary artery support comprises a circumferential-dilatable metal support; and an isolating membrane, wherein the isolating membrane wraps the metal support so as to isolate the metal support from an external environment, and the circumferential tensile strength of the isolating membrane is lower than the axial tensile strength of the isolating membrane. According to the pulmonary artery support disclosed by the embodiments of the invention, the diameter of the support can be dilated according to diameter changes of blood vessels so as to meet the requirements of the blood vessels on supporting performance after being enlarged, and a metal portion of the support can be isolated from a blood vessel environment, so that the problem that the interior of the bracket is subjected to restenosis is effectively solved.

The invention discloses functions and application of SHPS1 in treatment of post-vascular injury restenosis, belonging to the field of functions and applications of genes. SHPS1 gene knockout mice and wild type mice are taken as experimental subjects, and due to a vascular injury model, the mouse neointima formation, vascular wall cell proliferation level and smooth muscle cell phenotype transform are detected. The result proves that SHPS1 gene knockout can obviously promote neointima neogenesis and cell proliferation and promote transformation of smooth muscle cells from a shrinkage manner to a synthetic manner. Thus the functions of SHPS1 in post-vascular injury restenosis are realized, which mainly shows that SHPS1 has the functions of inhibiting neointima formation and cell proliferation and inhibiting smooth muscle cell phenotype transformation. Aiming at the functions of the SHPS1, the SHPS1 can be used for preparing medicines and arterial stents for preventing, relieving and / or treating the post-vascular injury restenosis.

The invention discloses an iron-based alloy renal artery stent, and relates to the technical field of medical instruments. The iron-based alloy renal artery stent comprises a first end socket and an intermediate tube, wherein a connection large head is fixedly connected with one end of the first end socket, an inner buckle is fixedly connected with an inner wall of the connection large head, bothends of the intermediate tube are fixedly connected with connection small heads, outer buckles are fixedly connected with outer walls of the connection small heads, the inner buckle and the outer buckles are matched, and the connection large head is fixedly connected with the outer buckles on the connection small heads through the inner buckle. According to the iron-based alloy renal artery stent,by arranging the first end socket and a second end socket, after the first end socket and the second end socket, which are conical, are fixedly connected with the intermediate tube, the intermediatetube can always located in a hemadostenosis position, and due to the fact that the first end socket and the second end socket are conical, nether the first end socket nor the second end socket can gothrough the hemadostenosis position, so that the purposes of fixing the intermediate tube and preventing movement of the iron-based alloy renal artery stent in a blood vessel are achieved.

A stent designed to reduce risk of restenosis opens peripherally within a blood vessel so that, when deployed, a periphery of the stent has a longitudinal opening spanning a length of the stent, the longitudinal opening spanning between 30 and 170 degrees. The stent does not scrape or penetrate the blood vessel wall when it opens because the peripheral surface of the stent slides along an interior blood vessel wall without leading edges of the peripheral surface contacting the interior blood vessel wall.

The present invention relates to the use of propionyl L-carnitine and the pharmaceutically acceptable salts thereof for the preparation of medicaments useful in the treatment of pathologies whose treatment gains a benefit from inducement of apoptosis, in particular blood vessels, such as restenosis after angioplasty or coronary stenting, or in particular tumors.

The invention provides a cobalt-chromium alloy arterial stent system with a full biodegrade medical coating. The system comprises a transport system and a cobalt-chromium alloy arterial stent which has a full biodegrade medical coating and is sleeved on the transport system. The transport system comprises a push rod, a sacculus and a jacket respectively fixedly connected to both ends of the push rod, and a handle with a Luer joint. A cone-shaped hardened guide wire is arranged at the sacculus end of the push rod. The cobalt-chromium alloy arterial stent with the full biodegrade medical coating is sleeved on the sacculus. The system can avoid damage of the coating to the maximum extent, improve the retaining force between the bracket and the transport system greatly, prevent the probability that the bracket is out of load in the transport process, and reduce the clinical use risk, so that the problems of coronary artery stenosis and restenosis are effectively solved.

The invention relates to a branch type aorta artificial stent conveying device. The branch type aorta artificial stent conveying device comprises a conveyor, an artificial stent arranged in the conveyor and a catcher used for cooperating with the conveyor. The catcher is guided into branch arterial blood vessel, the conveyor is guided into the focus position of the aorta, then a soft sheath is fixed, an outer tube is gradually withdrawn to expose branch guide wires, then the catcher is used for catching the branch guide wires, and therefore, branch arterial stents are guided into the branch arterial blood vessel through the branch guide wires. In the surgical operation process, due to the fact that the branch guide wires are not reserved on the aorta in advance, the phenomena of crossing and winding of the guide wires cannot occur, the surgical operation difficulty is reduced, the surgical operation is simpler, the surgical time is shortened, and the surgical risk is reduced.

The invention relates to a coronary stent based hemorheological monitoring device and a coronary stent based hemorheological monitoring method. The device is characterized by comprising a coronary stent, an integrated circuit and external processing equipment; the coronary stent serves as an antenna, and the integrated circuit is fixed to a blood vessel of the coronary stent; the integrated circuit comprises an energy supply module, a hemorheological detection module, a memory, a data processor and a first radio-frequency transceiving module, and the energy supply module is used for supplying power to the integrated circuit; the hemorheological detection module transmits detected hemorheological signals to the data processor through the memory, and then the data processor converts the hemorheological signals into digital signals and transmits the digital signals to the external processing equipment through the coronary stent by the aid of the first radio-frequency transceiving module.

The invention discloses a vertebral artery stent. Aiming at the problem of restenosis after implantation of a stent of a starting portion of a vertebral artery, the vertebral artery stent with an asymmetric ellipse-like section is designed. The vertebral artery stent consists of annular supporting bodies which are longitudinally stacked and connecting ribs for connecting the adjacent annular supporting bodies. The two sides of the stent are divided into two arc-shaped side faces with large curvature and small curvature, different degrees of supporting can be carried out according to the characteristics of blood vessels of the starting section of the vertebral artery, the blood vessel walls are subjected to different supporting forces, an asymmetric blood vessel section is formed, and therefore, a hemodynamic environment in the blood vessel is changed. Meanwhile, in the stent, the large-curvature sides and the small-curvature sides of the adjacent annular supporting bodies are connectedthrough the connecting ribs having different structures, the directions of the stent can be distinguished conveniently, and therefore, the direction can be better distinguished when the stent is implanted into the blood vessel of the vertebral artery.

A method includes the steps: generating a 3-D model of an unstenosed geometry of a blood vessel responsive to a 3-D model of an actual geometry of the blood vessel, establishing a parametric description of a stent that is expanded from a collapsed configuration to a final configuration that apposes the unstenosed geometry, developing a design for the stent by varying parameters of the parametric description responsive to a design heuristic that includes risk of stent strut breakage during a plastic deformation between the collapsed configuration and the final configuration, embodying the stentaccording to the design for the stent, inserting the stent info a blood vessel in its collapsed configuration, maneuvering the stent through the blood vessel to a stenosis, and expanding the stent toits final configuration.

The invention relates to the technical field of vascular intervention, in particular to an infant pulmonary artery stent. The stent is of a balloon dilatation type and comprises a plurality of net-tube-shaped unit joints and connecting rods, wherein each unit joint comprises a plurality of joint rods connected end to end, and the unit joints define a ring; the connecting rods are connected to the adjacent unit joints, the number of the joint rods in each unit joint is 12-30, the connecting position of every two joint rods is in arc transition, the connecting rods are evenly distributed in the circumferential direction of the unit joints, the connecting position of one connecting rod is arranged with an interval of at least one arc transition, and the connecting positions of the adjacent unit joints are correspondingly connected through the connecting rods. The infant pulmonary artery stent is suitable for infants, has good flexibility and can meet the requirement for interventional therapy of infant patients.

The invention provides a restenosis monitoring device and method based on an intelligent coronary stent. The device comprises a first blood state detection device, a second blood state detection device, a third blood state detection device and an external data processing device; wherein each blood state detection device comprises: a sensor group, an internal processor, an energy supply device anda radio frequency emission module; the external data processing device comprises a radio frequency receiving module, a memory and a data processor; the radio frequency receiving module is used for receiving an electric signal from the radio frequency emission modules, the memory is used for storing the electric signal, and the data processor periodically retrieves the electric signal from the memory; when the value of a blood state function G is within a judgment interval [delta]Sn, the external data processing device does not work; and when the value of the blood state function G is outside the judgment interval [delta]Sn, the external data processing device simultaneously sends an alarm notification to a patient and a hospital.

The invention discloses a coronary artery stent implantation surgery image operation platform which comprises a supporting table, a rotating groove is formed in the supporting table, a rotating rod is rotationally connected to the rotating groove, a supporting rod is fixedly installed at the upper end of the rotating rod, a lifting groove is formed in the supporting rod, a lifting rod is slidably connected into the lifting groove, and a rotating shaft is arranged in the lifting rod. And moving blocks are fixedly mounted on the left side and the right side of the lifting rod correspondingly, moving grooves are formed in the left side and the right side of the lifting groove correspondingly, the two moving grooves are matched with the two moving blocks correspondingly, and sliding rods are fixedly mounted on the two moving blocks correspondingly. The medical image display device has the advantages that doctors standing at different positions can clearly check images in the body of a patient, so that the success rate of an operation can be improved to a certain extent, the mounting height and the vertical angle of the display screen can be adjusted according to needs, the doctors can better clearly check the images on the display screen, and the operation efficiency is improved. And the application range is wider.

The invention discloses a cross-supporting spiral popliteal artery stent, which comprises support rings and connecting rods, the support rings and the connecting rods are alternately connected, and the two ends of the stent are support rings. Among them, the support ring includes a clockwise helix and a counterclockwise helix, and multiple clockwise helixes and multiple counterclockwise helixes are arranged at equal intervals on a virtual cylindrical surface with a radius R, and multiple clockwise helixes and multiple The counterclockwise helical lines intersect; the connecting rod includes a right-handed helical line, and a plurality of right-handed helical lines are arranged at equal intervals on the cylindrical surface, and a plurality of right-handed helical lines are connected with multiple intersection points on the circumference of the bottom surface of the support ring; the support ring is connected with the The rod has a winding height ratio of 1 or less. The cross-supported helical popliteal artery stent has excellent flexibility, sufficient adaptability to axial compression, sufficient torsion capacity, and sufficient radial support force. The stent provides support for blood vessels and is not prone to radial compression under load.