The invention relates to an anti-malarial medicine capsule and a preparation method thereof. The anti-malarial medicine comprises the following ingredients in parts by mass: 20-30 parts of verbena, 17-25 parts of ching-chieh, 8-13 parts of the root of red-rooted salvia, 4-10 parts of curcuma zedoary, 10-15 parts of centella asiatica, 7-13 parts of radix paeoniae rubra, 8-12 parts of angelica sinensis, 3-8 parts of carthamus tinctorius, 4-9 parts of folium mori, 1-6 parts of grevllia, 25-44 parts of starch, 5.8-10 parts of sodium carboxymethyl starch and 1.2-2 parts of magnesium stearate. The anti-malarial medicine provided by the invention is capable of treating symptoms such as blood heat, vital energy deficiency, meridian symptom acerbity, stasis and impassability, numbness of limbs, skin ulcer caused by muscle heat, and body pain and fatigue, and as the medicine is prepared into capsules, the oral bioavailability can be improved.