77 results about "Anti inflammatory treatment" patented technology

A method for laser anti-inflammatory treatment of painful symptomatologies and for tissue regeneration includes generating a pulsed laser beam with laser at a wavelength between 0.75 and 2.5 micrometers. The laser energy is conveyed to a hand unit where the laser beam is preferably defocused. The operator then applies the defocused laser beam the skin of a patient in need of treatment. The average power density per pulse of the defocused laser beam on the skin being 8 W/cm² per pulse or more.

The invention discloses isobenzazole compounds derived from marine fungi, a preparation method of the isobenzazole compounds and application of the isobenzazole compounds in the preparation of anti-inflammatory drugs. The structural formulae of the isobenzazole new compounds are represented by a formula I, II, III or IV. The new compounds are capable of remarkably inhibiting the generation of LPS-induced NO and can be used for preparing the anti-inflammatory drugs, and the IC50 of the compounds are respectively 8.9mM(I), 12.4mM(II), 18.2mM(III) and 22.7mM(IV). Therefore, the isobenzazole compounds have the clinical application potential in the anti-inflammatory treatment.

The invention discloses an Excoecaria agallocha endophytic fungus sourced indene derivative, and applications thereof in preparation of anti-inflammatory drugs. The Excoecaria agallocha endophytic fungus sourced indene derivative is obtained via separation from Excoecaria agallocha endophytic fungus Diaporthe sp.SYSU-HQ3, the Excoecaria agallocha endophytic fungus Diaporthe sp.SYSU-HQ3 is preserved at Guangdong Microbial Culture Collection Center on 4th, August, 2017, and the preservation number is GDMCC No:60217. The Excoecaria agallocha endophytic fungus sourced indene derivative is capableof inhibiting generation of LPS induced NO obviously, possesses clinical application potential in anti-inflammatory treatment, can be used for preparing anti-inflammatory drugs, and is promising in application prospect, the IC<50> is 8.5mM(1), 5.9mM(2), 4.2mN(3), and 4.2mM(4).

The present invention relates to an oridonin functionalized selenium nanoparticle, method of preparing and use thereof for anti-cancer and anti-inflammatory treatments. The present invention provides oridonin functionalized selenium nanoparticle that is stable, water soluble and storable.

The invention relates to the field of drug research and development and particularly discloses an application of a compound HUBIN-1 in preparation of a drug for preventing and/or treating liver inflammatory diseases. Extensive and deep research discovers the hepatocyte protection function and the anti-inflammatory treatment function of the compound HUBIN-1 for the first time, the compound HUBIN-1 is applicable to various types of liver inflammations, and the application field of the compound HUBIN-1 is broadened. The novel drug for preventing and/or treating various liver inflammatory diseases such as acute hepatitis, chronic hepatitis and severe hepatitis (hepatic failure) which include viral hepatitis, drug-induced hepatitis, nonalcoholic fatty liver disease, alcoholic hepatitis, autoimmune hepatitis and the like is provided and has remarkable social benefits.

Compounds useful in immunosuppressive and anti-inflammatory treatment are described. The compounds are hydrolyzable triptolide analogs with improved water solubility and generally lower toxicity than the parent compound.

The invention discloses an aspirin-based carbon quantum dot and application thereof in aspects of cell imaging and anti-inflammatory treatment, belonging to the technical field of nano-drugs. The invention in particular relates to a carbon quantum dot with strong fluorescent properties prepared from a hydrazine hydrate solution by utilizing a microwave heating method under the condition that aspirin dissolution is promoted. The carbon quantum dot prepared by the method is very stable under hyper-salt concentration and physiological pH conditions, blue-fluorescence is maintained, the carbon quantum dot can enter the cell nucleus, and the cells are effectively traced; and meanwhile, the original anti-inflammatory effect of aspirin is remained, and inflammatory cells can be effectively inhibited in an acute inflammation model constructed by utilizing carrageenin. In addition, the prepared aspirin carbon quantum dot is low in toxicity and does not influence liver and kidney functions and organs such as the heart, liver, spleen and kidney in in-vivo application, and the aim that the nanometer material has dual effects of diagnosis and treatment can be achieved.

The present invention makes it possible to enhance steroid efficacy in a steroid refractory or dependent patient afflicted with an inflammatory condition not responding or responding poorly or inadequately to anti-inflammatory treatment, by administering an oligonucleotide having the sequence 5 5′-Xm-CG-Yn-3′ in an effective amount to said patient and wherein X is A, T, C or G, Y is A, T, C, or G, m=1-100, n=1-100 and wherein at least one CG dinucleotide is ummethylated. The invention also encompasses the use of said oligonucleotide for the manufacture of pharmaceuticals.

The invention discloses seven withanolides compounds derived from cape gooseberries as well as a preparation method and application of the withanolides compounds, and relates to structures of five new(1-5) and two known (6-7) withanolides compounds in the cape gooseberries, a preparation method of the withanolides compounds and application of the withanolides compounds in anti-inflammatory and neurodegenerative disease treatment medicines. The compounds (2-4, 6, 7) provided by the invention have good NO inhibition activity, and can be used for development and application of anti-inflammatoryand neurodegenerative disease treatment drugs.

A kind of oxadiazole derivative is characterized by having a following formula, and R is shown as below. The oxadiazole derivative provided by the invention has obvious anti-inflammatory effect on ConA induced lymphocyte proliferation in mice. Therefore, the oxadiazole derivative provided by the invention can be used as a potential anti-inflammatory drug. The invention discloses the preparation method of the compound.