The invention discloses a high-temperature-resistant and high-salt-resistant fine gel particle as a profile control agent as well as a preparation method and an application of the fine gel particle. The preparation method of the fine gel particle comprises the following steps of firstly, adding modified starch, a monomer A, a monomer B, a crosslinking agent, an initiator and an accelerant into a reaction kettle according to a certain ratio; and after finishing the polymerization reaction of the six components to form integrated water-based gel, drying, crushing, granulating, screening and performing other process steps to obtain the fine gel particle. The application method of the high-temperature-resistant and high-salt-resistant fine gel particle is as follows: a certain quantity of fine gel particles prepared by using the preparation method are added into a Bingham fluid, the gel particles can be stably suspended without settling under static and dynamic conditions, and then, the whole fluid is injected to the stratum by means of pumping pressure. By using the high-temperature-resistant and high-salt-resistant fine gel particle and the application method thereof, disclosed by the invention, the construction success rate of the gel particle can be greatly increased, and a favorable deep profile control effect can be achieved.