The invention relates to a wind-dispelling and damp-clearing wine comprising 30g of long-nodded pit viper, 30g of ophidian black snake, 50g of earthworm, 20g of white silkworm, 20g of scorpio, 10g of chilopod, 20g of ground beetle, 10g of black ant, 30g of Chinese angelica, 30g of yam, 30g of liquorice, 60g of rhizome cibotii, 30g of aristolochina mollissima, 30g of rehmannia glutinosa, 30g of eucommia ulmoides, 30g of Chinese starjasmine stem, 30g of radices sileris, 30g of fourstamen stephania root, 30g of radix rehmanniae recens, 30g of notopterygium root, 30g of doubleteeth pubescent angelica root, 30g of mulberry twig, 30g of radix astragali, 30g of the root of bidentate achyranthes, 30g of clematis root, 30g of rhizoma chuanxiong, and 4000ml of high-quality white spirit with 60 degrees. The wind-dispelling and damp-clearing wine takes the high-quality white spirit as a carrier and makes the traditional medical effective disease treating elements fully solve in the carrier to specially treat rheumatism with exact medicine usage, proper dosage and strong pertinence; and the patient takes the medicine conveniently with small dosage and fast curative effect.