32results about How to "Prevention and treatment of viral diseases" patented technology

The invention discloses a feed additive and an application of the feed additive. The feed additive comprises the following ingredients in percentage by weight: 20 to 60 percent of monoglyceride laurate, 10 to 40 percent of calcium propionate and 0 to 50 percent of feed carriers. The feed additive disclosed by the invention is added into feed raw materials, the feed is prepared in a stirring mixing or extruding granulation mode, the growth propagation of mycetes can be effectively inhabited, the storage period of the feed in the damp and hot season is prolonged, and in addition, the effects of inhabiting the bacteria, resisting viruses, reducing the use of antibiotics in the feed, promoting the animal growth and improving the animal survival rate and the disease resistance capability are realized; and meanwhile, the feed additive has the advantages that the cost is low, the process is simple, the operation is convenient, the safety is high, and the feed additive is suitable for practical production.

Disclosed are phenanthrene-containing heterocyclic compounds shown as general formula (I) and preparation method therefor and application thereof on pesticides. The synthetic method of the compounds is simple and easy to industrialize. The phenanthrene-containing heterocyclic compounds can be used as plant virucides to inhibit tobacco mosaic virus, pepper virus, rice virus, tomato virus, sweet potato virus, potato virus, melon virus, maize dwarf mosaic virus and the like, particularly to inhibit tobacco mosaic virus. R1, R2, R3, X1-X7, m and n in general formula (I) are as defined in description.

The invention discloses a pest control method of watermelons. The pest control method comprises following control steps of: (1) seed sterilization: a. laying out and exposing watermelon seeds in the sun for 3 to 5 hours and flipping watermelon seeds one time per hour; b. putting soaking watermelon seeds into saline water at the concentration of 8 to 12% for about 0.5 to 1 hour; (2) cleaning of a melon field: thoroughly removing weeds in the melon field and the periphery of the melon field in the range of 5 to 8m and scattering 120-150g of lime powder per square meter and scattering 180 to 250g of sulphur powder per square meter two days later; (3).seeding stage: a. diluting ningnanmycin at the concentration of 1.5 to 2.5% for about 300 to 350 times, controlling once every 5 to 7 days by spraying and spraying 3 to 4 times; b. diluting 20g of a Jinjier wilt killer by utilizing water for 12 to 15Kg, controlling once every 10 to 12 days by spraying and spraying 2 to 3 times; and (4) flowering phase: a. diluting azadirachtin at the concentration of 0.2 to 0.4% for 800 to 1200 times, controlling once every 10 to 12 days by spraying and spraying 4 to 6 times; b. diluting the Jinjier wilt killer by utilizing water for 8 to 12 Kg, controlling every 8 to 10 days by spraying and spraying 2 to 3 times. The pest control method of watermelons is adopted in order to effectively control pests.

The invention relates to a tryptophan derivative (I), a preparing method of the tryptophan derivative (I), and application of the tryptophan derivative (I) in preventing and treating plant viruses, killing bacteria and killing insects. The formula of the tryptophan derivative (I) is shown in the description, and the meanings of all groups in the formula are shown in the description. The tryptophan derivative expresses especially excellent plant virus resisting activity, and also has broad-spectrum bactericidal activity and insecticidal activity.

The invention discloses a nematicidal disease-resistant composition and application thereof. The composition comprises the active ingredients of fluensulfone and lentinan, and the mass ratio of fluensulfone to lentinan ranges from 1:80 to 80:1. The composition has a significant synergistic effect, can prevent and treat nematodes of the whole crop growth period, can improve the immunity of crops and has a good preventing and treating effect on soil-borne diseases such as virus diseases and blight.

The invention belongs to the technical field of biological medicines, and in particular belongs to an iodine disinfection solution for preventing and treating freshwater biological virus erosion. The iodine disinfection solution comprises the following components in parts by weight: 5-10g of povidone iodine, 1.65-3.3g of potassium iodate, 1.0-2.0g of potassium iodide and a proper amount of a pH adjusting agent. The pH value is adjusted to 5.0-5.5, and water is added to reach 100ml. The iodine disinfection solution disclosed by the invention can be used for effectively preventing and treating various viral diseases of seawater and freshwater aquatic animals, and has relatively good treatment effects on various bacterial diseases caused by pathogenic bacteria such as vibrios, aeromonas hydrophila, edwardsiella tarda, chloroflexi and pseudomonas. In addition, the iodine disinfection solution disclosed by the invention is low in production cost and convenient to use, and is suitable for popularization and application in related technical fields.

The invention discloses an organic cultivation method for yacon trees and belongs to the field of planting. The organic cultivation method comprises the steps of selecting land, preparing the land, selecting seeds, sowing the seeds, conducting field management and harvesting. Ridging and membrane covering are adopted in the planting mode. The width of ridges is 55-65 cm, the height of the ridges is 35-40 cm, and the space between the ridges is 110-130 cm. After yacon seed stems are treated through a potassium permanganate solution, the hole sowing mode is adopted for planting. Compared with the prior art, the organic cultivation method has the following advantages that the growth period is short, the yield is high, and quality and mouthfeel are good; the method is simple, convenient to popularize and suitable for mass production; vegetable seed cake fertilizer is used, and the fertilizer efficiency is good in comprehensiveness and lasting; the ridging and membrane covering method is adopted, soil thermal insulation and moisturizing are facilitated, the ridge space is set to be wide, plants can fully receive sunshine and ventilation, and the air permeability of soil is improved; cultivated yacon is large in size and plump.

The invention relates to a bactericidal composition containing an alternaria tenuissima activator protein. The alternaria tenuissima activator protein and a compound A serve as active ingredients, andthe compound A is a tetrahydro-beta-carboline compound containing an acylhydrazone structure. The composition can be used for controlling viral diseases of fruit trees, vegetables and field crops andcan achieve the effects of effectively improving stress resistance of the crops, regulating growth of the crops, promoting flowering, improving yield, improving the fruit quality and the like.

The invention relates to an N-(1, 2-diphenyl-2-amino)-thiophosphoramide salt compound and application thereof. The structural formula of the compound is shown as the specification (with the definitions of the groups being shown in the specification). The compound provided by the invention is applied to inhibition of tobacco mosaic virus, pepper virus, tomato virus, sweet potato virus, potato virus, cucurbit virus and maize dwarf mosaic virus, can effectively control the virus diseases of tobacco, hot pepper, tomatoes, cucurbites, grains, vegetables, beans and other crops, and is especially suitable for control of tobacco mosaic virus. (structural formula).

The invention relates to a simple method for preparing fermentation liquor of vegetable and fruit agricultural products. According to the invention, vegetable and fruit agricultural products are fermented to obtain the fermentation liquor, so that the original traditional Chinese medicine efficacies of the vegetable and fruit agricultural products are enhanced, and the simple method can be applied to the fields of medical care and illness prevention and treatment; the situation that the vegetable and fruit agricultural products are disposed as garbage is avoided, the comprehensive energy utilization ratio and the additional value of the vegetable and fruit agricultural products resources can be obviously improved, and the purposes of energy conservation and environmental friendliness are achieved; the operation is simple, the simple method is suitable for various large-scale and small-scale production, and is low in cost and high in gain; and the energies of the vegetable and fruit agricultural product resources are more reasonably and sufficiently utilized. The simple method comprises the following steps of: cutting up at least one vegetable or fruit, smashing or stamping into mud juice; sealing the mud juice into a container capable of being sealed, and placing in a sealed mode; fermenting under environment with the temperature being 12-65 DEG C for 7-100 days to obtain the fermentation liquor, wherein the PH value of the fermentation liquor is 6-9; filtering the formation liquor by metal gauze or gauze filtering device, filling the fermentation liquor after filtering into a container, and storing the fermentation liquor for standby use; and filling the remained material after filtering into the container capable of being sealed again.

The invention discloses a feed additive and an application of the feed additive. The feed additive comprises the following ingredients in percentage by weight: 20 to 60 percent of monoglyceride laurate, 10 to 40 percent of calcium propionate and 0 to 50 percent of feed carriers. The feed additive disclosed by the invention is added into feed raw materials, the feed is prepared in a stirring mixing or extruding granulation mode, the growth propagation of mycetes can be effectively inhabited, the storage period of the feed in the damp and hot season is prolonged, and in addition, the effects of inhabiting the bacteria, resisting viruses, reducing the use of antibiotics in the feed, promoting the animal growth and improving the animal survival rate and the disease resistance capability are realized; and meanwhile, the feed additive has the advantages that the cost is low, the process is simple, the operation is convenient, the safety is high, and the feed additive is suitable for practical production.

The invention provides a method for resisting tobacco mosaic virus activity through a thiourea compound and relates to a plant virus resisting agent of a chemical compound. The method comprises the following steps that A, the thiourea compound is a compound provided with a structure shown by the following general formula (I), and please see the general formula in the specification; B, the tobacco mosaic virus activity resisting method of the thiourea compound comprises the subsidiary steps of tobacco mosaic virus refinement and concentration determination, preparation of a selected thiourea compound medicament solution, the in-vitro effect, the in-vivo protection effect, the in-vivo treatment effect and the in-vivo inactivation effect. The compound is used for preventing and curing the activity of diseases caused by tobacco mosaic viruses, and is better than chemical compounds and drugs in the prior art, low in production cost and capable of being widely applied to the agriculture.

The invention provides a method for improving the antiviral immunity of fishes. The antiviral immunity of the fishes is enhanced by increasing the expression amount of Bmp8a protein. The invention firstly provides use of the Bmp8a protein, which is application of the Bmp8a protein in the preparation of a product for improving the antiviral immunity of the fishes. According to the method, it is proved that the antiviral capacity of zebra fishes after bmp8a gene knockout is significantly reduced, over-expression of the Bmp8a can significantly up-regulate the expression of antiviral related genessuch as interferon, and it is shown that the Bmp8a plays an important role in the antiviral immunity. Bmp8a mature peptides are injected in the fishes, which enhances the antiviral immunity of the fishes, thereby achieving the purpose of preventing and treating viral diseases of the fishes.

The invention relates to a 2-alkenyl substituted quinoline derivative, a preparation method and application thereof in prevention and treatment of plant viruses and sterilization. The significance of each group in the general formula is shown as the specification. The 2-alkenyl substituted quinoline derivative disclosed by the invention has anti-plant virus activity and broad-spectrum bactericidal activity.

The invention discloses application of a substituted azole compound, represented by a general formula I shown in specifications, as a plant virus resisting agent. In the formula, all substituents are as defined in the specifications. The compound represented by the general formula I has very good plant virus resisting activity and can be used for preventing and treating virus diseases of a variety of crops, such as tobacco, vegetables, fruit trees, legumes, cereals and potatoes.

The invention relates to a cerbera manghas aldehyde derivative, namely cyclopentenopyridine, as well as a synthesis method and application thereof in plant protection, and belongs to the technical field of pesticides. The invention finds that a natural product, namely cerbera manghas aldehyde, has activity of plant virus prevention, insect killing and sterilization for a fist time, the natural product can be used as a novel plant source pesticide or can be developed as a lead compound, and secondly, a simple and efficient synthesis method for preparing cyclopentenopyridine from genipin as a raw material is found. Plant virus activity resistance tests of the cyclopentenopyridine provided by the invention show that the cyclopentenopyridine has activity on tobacco mosaic viruses, and the activity is prior to that of the lead compound cerbera manghas aldehyde; and insect killing and sterilization activity tests show that most compounds have very good activity on plutella xylostella, and inaddition have activity on 14 plant pathogenic bacteria.

The invention discloses application of a substituted ether and thioether compound, represented by a general formula I shown in specifications, as a plant virus resisting agent. In the formula, all substituents are as defined in the specifications. The compound represented by the general formula I has very good plant virus resisting activity and can be used for preventing and treating virus diseases of a variety of crops, such as tobacco, vegetables, fruit trees, legumes, cereals and potatoes.

The invention relates to a method for fully synthesizing natural product cerbinal and application in plant protection, and belongs to the technical field of pesticides. The method comprise the steps that genipin is used as a raw material; the first step, the raw material genipin is oxidized by IBX to obtain a compound 1; and the second step, DDQ and acid are added, and the compound 1 is oxidized and dehydrated to obtain the cerbinal. The method does not adopt a protecting group strategy, first, IBX only oxidizes a primary hydroxyl group and does not react with an acetal hydroxyl group to obtain an intermediate 1; and then, oxidative dehydrogenation and elimination of dehydration are completed simultaneously, the natural product cerbinal is synthesized only in two steps, a synthetic route is significantly shortened, and the application prospects are good. It is found the first time that the natural product cerbinal has anti-plant virus, insecticidal and bactericidal activity by the method, and the cerbinal can be developed as a novel plant-derived pesticide or as a lead compound.

The invention provides a pesticide composition. The pesticide composition comprises dufulin and a dithiocarbamate bactericide, wherein the dithiocarbamate bactericide is one or more selected from propineb, metiram, mancozeb, thiram, zineb and ziram; the weight ratio of dufulin to the dithiocarbamate bactericide is (5:1)-(1:100). The invention also provides a bactericide containing the pesticide composition, wherein the pesticide composition takes up 0.1-90% of the total weight of the bactericide. The pesticide composition and the bactericide provided by the invention show an obvious synergistic effect relative to a single dosage, improve the preventive and treating effects, are suitable for preventing and treating various viral diseases and most fungal diseases, and are an ecological pesticide with relatively high safety and extremely low toxicity.

The invention discloses a premix used for preventing and treating viral diseases of shrimps and crabs. The premix used for preventing and treating the viral diseases of the shrimps and crabs comprisesthe following raw materials: bentonite, fine wheat bran powder, iron, copper, zinc, manganese, potassium iodide, sodium selenite, vitamin A, vitamin D3, vitamin E, vitamin K3, vitamin B1, vitamin B2,vitamin B6, vitamin B12, vitamin C, nicotinic acid, biotin, folic acid, calcium pantothenate, inositol, oxytetracycline, a flavoring agent, a sweetener, and traditional Chinese medicine powder. By improving proportion of the raw materials, the contents of the various trace elements and the vitamins are more balanced; moreover, the traditional Chinese medicine powder capable of preventing and treating the viral diseases is added so that the premix is capable of effectively preventing and treating viral diseases of the shrimps and crabs. The invention further discloses a preparation method of the premix used for preventing and treating the viral diseases of the shrimps and crabs. The preparation method has processes which can be easily standardized, and is suitable for large-scale production; and thus, the preparation method is of great significance to improvement of product competitiveness of enterprises, expansion of market share, promotion of technological innovations and technological progresses of enterprises, and so on.

The invention relates to a RNA interference sequence targeting a cucumber mosaic virus, an expression vector thereof and application. The cucumber mosaic virus targeted RNA interference sequence is double-stranded RNA, is composed of a sense strand and an antisense strand, and is an interference sequence GT1 of a GT1 gene specifically targeting CMV-1a protein, or an interference sequence GT2 of a GT2 gene specifically targeting CMV-1a protein, or an interference sequence GT3 of a GT3 gene specifically targeting CMV-2a protein, or an interference sequence GT4 of a GT4 gene specifically targeting CMV-2a protein, or an interference sequence GT5 of a GT5 gene specifically targeting CMV-CP protein, or an interference sequence GT16 of a GT6 gene specifically targeting CMV-MP protein. The double-stranded RNA interference sequence is used for degrading target messenger RNA, reducing expression of target protein, effectively silencing CMV genes and controlling CMV infection, and has the characteristic of environmental friendliness and high commercial application value.

The invention discloses application of a substituted ether and thioether compound, represented by a general formula I shown in specifications, as a plant virus resisting agent. In the formula, all substituents are as defined in the specifications. The compound represented by the general formula I has very good plant virus resisting activity and can be used for preventing and treating virus diseases of a variety of crops, such as tobacco, vegetables, fruit trees, legumes, cereals and potatoes.

The invention discloses a stomach cleaning combined medicament for a gastroenterology department, relates to the field of the gastroenterology department, and mainly solves the problem of regulation after gastric lavage. The stomach cleaning combined medicament for the gastroenterology department comprises the following raw materials in parts by weight: 20-40 parts of a pansy extracting solution,30-50 parts of a hibiscus syriacus extracting solution, 20-30 parts of blueberries, 15-30 parts of a high-fragrance tea flower extracting solution, 8-10 parts of a chrysanthemum extracting solution, 50-100 parts of normal saline, 2-6 parts of humus flava usta, 10-50 parts of agarwood, 20-30 parts of fennel seeds, 2-5 parts of millets, 12-20 parts of endothelium corneum gigeriae galli, 5-10 parts of fructus forsythiae, 11-20 parts of royal jelly, 10-15 parts of barley, 3-8 parts of a honeysuckle extracting solution, 10-14 parts of ginseng, 8-13 parts of radix codonopsis, 5-10 parts of endothelium corneum gigeriae galli and 60-90 parts of 10% potassium chloride solution. The stomach cleaning combined medicament for the gastroenterology department not only has an effect of cleaning the stomach, but also facilitates nursing and healing of the stomach; and recovery of the stomach in the later period is facilitated.

The invention relates to the technical field of planting, in particular to a cultivation method and application of green food cucumbers. Physical insect prevention is carried out in different growth stages of cucumber plants under the cooperation of warm water seed soaking, base fertilizer, a sunshade net, an insect prevention net and a yellow plate, plant diseases and insect pests can be reduced,meanwhile, use of chemical pesticides can be reduced, and it is guaranteed that the green food production requirement is met. The problems that an existing green cucumber planting method is complex,the fertilizer using amount is high, the water amount is large, and the yield is low are solved.

The invention discloses a composition for preventing and controlling a plant virus disease and application thereof and relates to the technical field of pesticide compositions. Active components of the pesticide composition are a first active component iodine oligosaccharide acid and a second active component imidacloprid, thiamethoxam, clothianidin and nitenpyram or dinotefuran, and weight ratio of the first active component to the second active component is 1:(0.01-90). The invention also relates to a pesticide prepared from the pesticide composition and application of the pesticide in prevention and control of the plant virus disease. The pesticide composition has obvious prevention and control effects, also has obvious synergistic effect, can be used for preventing and controlling the virus disease of multiple plants such as rice, corn, wheat, cotton, peanut, tobacco, vegetables and flowers and can effectively improve health of crops.

The invention discloses a compound probiotic agent containing chicken alpha interferon and a preparation method thereof. Firstly, a method for preparing chicken interferon alpha is provided, which is to add the fermentation liquid of recombinant bacteria expressing chicken interferon alpha to boiled benzoic acid, filter or centrifuge with a ceramic membrane, and then add a certain amount of After the maltodextrin is dissolved, it is spray-dried to obtain the chicken alpha interferon powder preparation. It is further mixed with Bacillus subtilis powder, Saccharomyces cerevisiae powder, Lactobacillus reuteri powder, Lactobacillus plantarum powder and Fumei powder to form a compound probiotic agent containing chicken alpha interferon. The compound probiotic agent can be used as a feed additive for poultry and livestock or directly mixed with water orally. It can regulate the microecological balance of the gastrointestinal tract of animals, inhibit the growth of pathogenic bacteria, significantly improve the growth level of laying chicks and the utilization rate of feed, and play a role Antiviral and immunomodulatory effects can reduce or replace the use of antibiotics, reduce the occurrence of drug-resistant bacteria and solve the problem of drug residues.

The invention provides a pesticide composition. The pesticide composition comprises dufulin and a dithiocarbamate bactericide, wherein the dithiocarbamate bactericide is one or more selected from propineb, metiram, mancozeb, thiram, zineb and ziram; the weight ratio of dufulin to the dithiocarbamate bactericide is (5:1)-(1:100). The invention also provides a bactericide containing the pesticide composition, wherein the pesticide composition takes up 0.1-90% of the total weight of the bactericide. The pesticide composition and the bactericide provided by the invention show an obvious synergistic effect relative to a single dosage, improve the preventive and treating effects, are suitable for preventing and treating various viral diseases and most fungal diseases, and are an ecological pesticide with relatively high safety and extremely low toxicity.

The invention provides a method for improving the antiviral immunity of fish, which enhances the antiviral immunity of fish by up-regulating the expression of Bmp8a protein. The present invention first provides an application of the Bmp8a protein, which is the application in the preparation of a product for improving the antiviral immunity of fish. The present invention proves that the antiviral ability of zebrafish after the knockout of bmp8a gene is significantly reduced, while overexpression of Bmp8a can significantly upregulate the expression of antiviral related genes such as interferon, showing that Bmp8a plays an important role in antiviral immunity. By injecting Bmp8a mature peptide into fish, the antiviral immunity of fish is enhanced, so as to achieve the purpose of preventing and treating viral diseases of fish.