The invention discloses a method for machine-sewing a ball glued to close the mouth, which is applied to a football ball shell composed of a pentagonal skin and a hexagonal skin. The method includes drawing a line on the closed skin, cutting the skin, and applying glue Steps such as hemming, sewing the ball shell, installing the bladder, closing the seam with a high car, pasting Oxford cloth, kneading the leather, inflating the bladder, flattening and shaping, dispensing, etc., the present invention adopts the adhesive closing method, which does not require manual needlework closing. It avoids the occurrence of air leakage caused by the needle piercing the bladder, the operation is simple, the closing speed is fast, the technical proficiency of the workers is not high, and the work efficiency can be improved.