The invention provides a machine tool main shaft transport device, and belongs to the field of electromechanical devices. The machine tool main shaft transport device comprises rear wheels, a rear wheel motor, sliding blocks, cylindrical guide rails, a bottom plate, front universal wheels, a main motor, a main motor lead screw, main motor lead screw supports, a push rod, a height hydraulic cylinder, a length hydraulic cylinder and a main shaft ejector pin. The rear wheel motor is connected with the rear wheels through the support and arranged on the rear portion of the lower portion of the bottom plate, the front universal wheels are disposed on front part of the lower portion of the bottom plate, the two cylindrical guide rails are arranged in the middle of the upper portion of the bottom plate in parallel, the two sliding blocks are arranged on the cylindrical guide rails, the main motor lead screw is arranged between the left main motor lead screw support and the right main motor lead screw support, the sliding blocks are matched with the main motor lead screw through threads, the main motor is connected with the main motor lead screw through a gear set, the lower end of the height hydraulic cylinder is connected with the sliding blocks, the upper end of the height hydraulic cylinder is connected with the middle of the length hydraulic cylinder, the lower portion of the length hydraulic cylinder is connected with the sliding blocks, the front end of the length hydraulic cylinder is connected with the main shaft ejector pin, and the push rod is disposed behind the upper portion of the bottom plate. The machine tool main shaft transport device has the advantage of being capable of assisting in machine tool main shaft transport.