The invention relates to the field of traditional Chinese patches, and in particular relates to a medicinal paste for treating rheumatoid bone diseases and a preparation method thereof. The medicinal paste for treating rheumatoid bone diseases is prepared by fifty-three components in parts by weight: honeysuckle stem, siberia Monkshood, ground beetle, native copper, uncaria, Rhizoma Drynariae, cassia twig, radix aconiti agrestis, Schizophragma integrifolium, obscured homalomena rhizome, Vernonia gratiosa Hance, pawpaw, radix angelicae pubescentis, bloodvine, Manis pentadactyla, garden balsam stem, radix angelicae, flowers carthami, ramulus mori, Rhizoma Notopterygii, radix clematidis, Polygonum cuspidatum, ephedra, fox, Scorpio, asarum, radices sileris, long-noded pit viper, centipede, radix aconiti carmichaeli, borneol, musk, liquorice, Morinda officinalis, cinnamon, Eucommia ulmoides, sea horse and the like. The medical powder and minium powder are casted into soya-bean oil to be decocted and cooled to obtain the patch. Compared with the prior art, the medical paste provided by the invention has the beneficial effects that the effective rate of the product after 2-3 courses of treatment can reach 99%, and the efficiency reaches over 70%, can fundamentally treat rheumatic arthritis, scapulohumeral periarthritis and scapulohumeral periarthritis, and has better curative effect to hyperostosis, sprain, radiohumeral bursitis, lumbar disc herniation and the like.