The invention belongs to the technical field of traditional Chinese medicines and relates to use of a traditional Chinese medicine preparation in preparation of a drug for treating weakness-of-spleen-and-stomach type chronic gastritis. The traditional Chinese medicine preparation is prepared from atractylodes macrocephala, poria cocos, gordon euryale seed, coix seed, magnolia bark, hierochloe odorata, non-glutinous rice, angelica sinensis, panax ginseng and glycyrrhiza uralensis. The traditional Chinese medicine preparation complies with the prescription rule of assistant and guide, is appropriate in medication, strict in compatibility and clear between primary medicines and secondary medicines, gains mutually and can be used for reinforcing the spleen and nourishing the stomach, harmonizing stomach Qi, removing dampness and promoting diuresis, tonifying middle-Jiao and Qi and strengthening the spleen and replenishing Qi. The traditional Chinese medicine preparation for treating the weakness-of-spleen-and-stomach type chronic gastritis, disclosed by the invention, is strong in pertinence, high in effect showing speed, short in treatment course and high in cure rate. Medicated materials are all listed in the Chinese Pharmacopoeia, are simplified and are low in dosage, wide in source and low in cost, and a preparation process is simple and easy, so that the traditional Chinese medicine is suitable for industrial production.