158results about How to "Adverse effect" patented technology

An interchangeable lens to be detachably attached to a camera body, that includes a holding unit at which a plurality of contacts is arranged, the interchangeable lens includes: a first communication contact system arranged at the holding unit; and a second communication contact system different from the first communication contact system, arranged at the holding unit at a position different from a position at which the first communication contact system is arranged. The fourth contact is arranged at a position closer to the second communication contact system than the first contact, the second contact, and the third contact are, and the seventh contact and the eighth contact are arranged at positions closer to the first communication contact system than the fifth contact and the sixth contact are.

A compact orthodontic bracket that employs a simple method of self-ligation, is compatible with both permanent and deciduous teeth and is less expensive to manufacture than existing commercial brackets. The bracket utilizes a rotary plate that covers an arch wire slot when closed and can be pivotably opened to allow arch wire changes. Ligation may also be augmented using conventional ligatures on the paired tie wings. The simplicity of the ligating mechanism allows manufacturing of a smaller bracket. It is also less vulnerable to the clogging effects of salivary deposits than commercial self-ligating brackets currently in use.

A fully formulated lubricating oil, lubricated surface, and lubricant additive concentrates for lubricants providing reduced sludge formation. The fully formulated lubricating oil composition has therein at least one succinimide dispersant derived from a polyalkylene compound having from about 50 to about 85% vinylidene double bonds in the compound, a metal containing detergent, at least one wear reducing agent, at least one antioxidant, and a hydrocarbon soluble titanium compound as a friction modifier. The lubricating oil composition is also substantially free of molybdenum compounds.

A compensating advanced feature patch panel that can include removable modular or fixed electronic components located directly on the patch panel which are separately or in combination capable of providing advanced features such as device detection and power insertion. The patch panel provides communications between an insulation displacement connector (IDC) at a PD / User end, and any standard interface type using unshielded twisted pair cables, such as an RJ45 connector at a switch end at performance levels of at least category 3, 5, 5e, 6 and / or higher (e.g. 6e or 7) and equivalent performance levels as required by compensating for the active electronics used in providing advanced features through the use of inductive, capacitive and reactive circuit elements to compensate for advanced feature electronics.

The present invention provides a valvuloplasty catheter which has a scoring element at its distal part to score stenotic, calcified heart valves in radial direction and to make the single valve flaps / leaflets work again. In addition to this, the device could comprise an attached balloon to post-dilate the valve after the scoring procedure. To reduce a future recalcification, the scoring element and / or the balloon have a pharmacologic coating on their outer surface.

The present invention provides pyrazole derivatives represented by the general formula: wherein R1 represents H, an optionally substituted C1-6 alkyl group etc.; one of Q and T represents a group represented by the general formula: or a group represented by the general formula: while the other represents an optionally substituted C1-6 alkyl group etc.; R2 represents H, a halogen atom, OH, an optionally substituted C1-6 alkyl group etc.; X represents a single bond, O or S; Y represents an optionally substituted C1-6 alkylene group etc.; Z represents —RB, —CORC etc. in which RB represents an optionally substituted C1-6 alkyl group etc.; and RC represents an optionally substituted C1-6 alkyl group etc.; R4 represents H, an optionally substituted C1-6 alkyl group etc.; and R3, R5 and R6 represent H, a halogen atom etc., pharmaceutically acceptable salts thereof or prodrugs thereof, which exhibit an excellent inhibitory activity in human SGLT1 and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, impaired glucose tolerance, impaired fasting glycemia, diabetic complications or obesity, and a disease associated with the increase of blood galactose level such as galactosemia, and pharmaceutical compositions comprising the same, pharmaceutical uses thereof, and intermediates for production thereof.