According to the present invention, there is provided a medicament for
oral administration or intravenous administration that is effective for a
disease requiring enhancement of
nerve growth factor production, comprising as an effective ingredient a pulverized product and / or extract obtained from
Humulus lupulus and / or Angelica keiskei koidz., or
xanthohumol and / or a pharmacologically acceptable salt thereof. The medicament is useful as a therapeutic agent or prophylactic agent for a
disease requiring enhancement of
nerve growth factor production, such as
dementia or a nerve disorder. Also, according to the present invention, there are provided an enhancing agent for
nerve growth factor production, and a food, beverage or feed for enhancing nerve
growth factor production, each comprising the above effective ingredient. By taking the food or beverage as foodstuff on a daily basis, the symptoms of a
disease requiring enhancement of nerve
growth factor production can be ameliorated or the like. In addition, the feed is useful for maintaining
homeostasis of a
living body by its action of enhancing nerve
growth factor production. Furthermore, these medicament and the like of the present invention are effective for improving or ameliorating learning and memorizing ability of an individual
organism.