50 results about "Venous flow" patented technology

An apparatus for positioning a graft and catheter operable for subcutaneous access to the vascular system of a patient. A surgically created, hybrid arteriovenous shunt is provided which comprises a flexible graft and a venous outflow catheter connected to the graft via surgical anastomosis over a cuff. The graft is connected to an arterial source and then to a single lumen venous outflow catheter which deposits dialyzed blood directly into the heart at the right atrium. Methods of surgical placement and performing hemodialysis using embodiments of the apparatus are provided.

This application concerns novel methods which enable or improve the ability of molecules, particularly large molecules, to cross the blood-brain barrier, the blood-eye barrier, and / or the blood-nerve barrier and therefore be of improved diagnostic and / or therapeutic use in humans and other mammals. These methods involve perispinal administration of imaging agents without direct intrathecal injection. Perispinal administration is defined as administration of the molecule into the anatomic area within 10 cm of the spine. Perispinal administration results in absorption of the imaging agent into the vertebral venous system. The vertebral venous system is capable of transporting molecules into the brain, the eye, the retina, the auditory apparatus, the cranial nerves, the head, the spine, the spinal cord, the vertebral bodies, the dorsal root ganglia, and the nerve roots via retrograde venous flow, thereby bypassing the blood-brain barrier and similar barriers and delivering the molecules to the brain, the eye, the retina, the auditory apparatus, the cranial nerves, the head, the spine (including the vertebral bodies), the spinal cord, the dorsal root ganglia, or the nerve roots. This method may be utilized for a wide variety of diagnostic agents, including, but not limited to biologics, monoclonal antibodies, fusion proteins, monoclonal antibody fragments, antibodies to tumor antigens, hormones, cytokines, anti-cytokines, interleukins, anti-interleukins, interferons, colony-stimulating factors, cancer chemotherapeutic agents, growth factors, anti-virals and antibiotics, including those which are radiolabeled, iodinated, or otherwise altered to facilitate diagnostic imaging. Included in these novel methods are perispinal delivery of amyloid imaging agents, and other ligands radiolabeled with [11C] or [18F] to faciliate PET imaging of the brain.

A method is described for determining recirculation of blood in a vascular access of a patient undergoing dialysis treatment using a dialysis machine with an arterial line for withdrawing blood from the patient's body, a dialysis filter, and a venous line for returning blood to the patient's body. The method induces a disturbance in the blood flowing in the venous line. The disturbance is of a magnitude capable of bringing the system into a transient state and determining blood recirculation in the vascular access during the transient state as a function of the magnitude of the disturbance induced in the arterial line. In particular, the disturbance relates to the variation of the hemoglobin concentration in the blood flowing in the venous line. The variation is caused by controlling a change in the ultrafiltration flow in the dialysis filter.

The invention provides a cardiac coronary venous vascular exclusion device, and relates to the field of medical devices. The exclusion device includes a first catheter and a first sacculus. A proximalconnection part of the first catheter is connected to a filling mechanism; the first sacculus has an accommodation space therein; the first sacculus is communicated with the distal end of the first catheter; and the filling mechanism makes the first sacculus to be in a filling state through the first catheter. The device is placed in the vein to push the blood in the vein back into the cardiac muscle, thus avoiding myocardial ischemia caused by the inability of continuously supplying blood to the cardiac muscle due to arterial microvascular obstruction. By pushing the blood back to the cardiac muscle from the vein, the myocardial blood supply is guaranteed, and myocardial damage caused by no reflow is avoided.

The invention relates to the medical education technical field, and specifically refers to a full automatic vena epigastrica blood flow direction inspection standardized patient comprising high simulation human body models, a controller, a solenoid valve, a one way valve, a miniature blood circulating pump, and a blood storage bottle; the features are that belly walls of four high simulation human body models are respectively provided with a normal elder people belly wall vein, a belly wall vein with a blocked vein upper cavity, a belly wall vein with a blocked vein lower cavity, and a belly wall vein with a blocked portal vein; the embodiment 2 is that four vena epigastrica of different physical signs and internal structures are assembled in a model drum with equal belly distention diameter; a single chip can control to set different physical signs, so operation is simple and automation level is high; selection buttons of the controller can be controlled so as to automatically set physical signs, and automatic voice prompt can be realized; the full automatic vena epigastrica blood flow direction inspection standardized patient is simple in operation, vivid in simulation effect, suitable for medical students and medical personnel to carry out vena epigastrica blood flow direction inspection skill training and examination, thus obviously improving teaching effect.