166 results about "Triggered release" patented technology

The present invention relates to an improved controlled release system that can be incorporated into anhydrous cosmetic formulations and can encapsulate different types of fragrances, flavors, active ingredients, or combinations of fragrances, flavors, and various active ingredients. The controlled delivery system of the present invention is substantially free-flowing powder formed of solid hydrophobic nano-spheres that are encapsulated in a moisture sensitive micro-spheres. The fragrances, flavors, and active ingredients encapsulated in the nano-spheres can be the same or different from those encapsulated in the micro-sphere. The encapsulation of one or more fragrances, flavors or active agents in the various components of the system, such as nano-spheres and micro-spheres, provides odor or flavor transition (change in odor character or change in flavor character) during the use of the product, in response to moisture, such as wetting the lips, perspiration, and the like. The incorporation of the controlled release system of the present invention into anhydrous cosmetic formulations was found to provide moisture triggered release, as well as prolonged release of the fragrances, flavors, and active ingredients that are encapsulated in the solid hydrophobic nano-spheres over an extended period of time.

The present invention relates to novel therapeutic and diagnostic arrays. More particularly, the present invention is directed to dendrimer based multifunctional compositions and systems for use in disease diagnosis and therapy (e.g., cancer diagnosis and therapy). The compositions and systems generally comprise two or more separate components for targeting, imaging, sensing, and / or triggering release of a therapeutic or diagnostic material and monitoring the response to therapy of a cell or tissue (e.g., a tumor).

One embodiment of a trigger system with an integral selector for semi-automatic firearms. A selector allows the user to choose between two modes and rates of fire. A trigger (1) is made to allow passage of the lower portion of a selector cam (5) to the exterior of the firearm. A selector lever (6) is affixed to the lower end of the selector cam (5) on the exterior of the firearms action. Turning the selector lever (6) rotates the selector cam (5) which tilts a pivotal disconnector (3) on its axis, varying the amount of disconnector (3) engagement with a hammer (2). The variance in the disconnector (3) engagement causes the firearm to fire in one of two modes, firing one round with a trigger pull and resetting with trigger release, or firing one round with trigger pull, and firing another round with trigger release. Other embodiments are described.

A preloadable trigger-release-clip that may be ceiling triggered for lighting module installation is described, including systems and methods of use. The trigger-release-clip may include a base-plate, a trigger, a clip, and a stop. The base-plate may be a structural member that attaches to a lighting module. The trigger may be in communication with the base-plate. The clip, with a torsion-spring, may be in communication with the base-plate. The stop may be in communication with the trigger. In a pre-loaded configuration, the stop may be in an up position that prevents the clip from actuating. In a final configuration, the stop has been retracted into a down position by the trigger being depressed by a bottom of a ceiling that may allow the clip to actuate, such that a terminal end of the clip pivots to grab a top of the ceiling securing the lighting module to the ceiling.

A drop tester (1) including a gripper mechanism (2) for holding a product (37) to be tested, a guide track, a slider block (3) which is mounted to slide along the guide track and advance the mechanism toward a target location (41) and a release device (40) for triggering release of the product from the mechanism to impact at the target location, characterised in that the gripper mechanism includes gripper arms (15, 16) coupled to the slider block, the gripper arms being rotatable relative to the slider block to enable the orientation of the product to be varied, relative to the target location. The slider block is preferably releasably coupled to a hoisting block (4) which is positionable at a predetermined location along the guide track. More preferably, the gripper arms are pivotally mounted to a housing (23) and coupled to a piston (22) provided within the housing, the arms pivoting between a gripping position and a release position upon advancement of the piston through the housing.

The present invention provides particle conjugates for drug delivery. Such conjugates comprise one or more heatable surfaces, one or more thermally-responsive linkers, and one or more agents to be delivered. In some embodiments, conjugates and populations of conjugates can be used to treat and / or diagnose a disease, disorder, and / or condition. The present invention provides methods for producing and / or using thermally-responsive conjugates.

A kit is provided to convert a compound archery bow into a left or right handed inline (vertical limb) crossbow. The conversion kit includes a mounting plate attachable to a side of the bow riser section to hold a socket to receive a draw-lock bar which can be removed for take-down and storage. The draw-lock bar has a series of laterally spaced bolt holes to attach a grip with a trigger release latch assembly at a selectable draw length. The bar can be rotated and attached to either side of the bow, and the trigger and grip can be reposition within the trigger housing for left, right or horizontal shooting. The string latch assembly has an anti-dryfire lever that is only moved from the blocking position when an arrow is nocked. The kit also provides a hinged cocking stirrup, and a front hand vertical grip on the riser side opposite the draw-bar socket. Also disclosed is a dedicated hybrid compound bow for dedicated use with kit as an inline or traditional crossbow. The hybrid compound bow is made especially. The hybrid bow has no forehand grip, and has a shoot through riser to provide vertical and horizontal centering of the arrow to the string.

The present invention comprises a novel hammer and biasing system in a paintball pistol to achieve automatic re-cocking with closed bolt results in a marker pistol configuration typically associated with open bolt systems. The trigger releases a compressions hammer that nests in a hammer sleeve, but an aperture in the hammer sleeve permits a protrusion on the compression hammer to strike a poppet valve which releases a burst of gas. The gas pressure forced into the barrel causes the paint ball to be expelled from the barrel, and forces the hammer and bolt assembly aft due to increased pressure in the lower bore. The pressure against the front wall of a hammer sleeve pushes the hammer sleeve aft, along with the compression hammer. Also, because the bolt is interconnected to the hammer sleeve it is forced back in the upper barrel as well. When forced back, the bolt allows the breach to open and a paintball to drop into the chamber. Also, the sear catches the compression hammer in the cocked position. The interconnected combination of the hammer sleeve, bolt and slide cover causes the slide cover to move back as well. Springs interconnected between the slide cover and the housing are stretched when the slide cover moves back, but biases the slide cover to return to its forward position. Because the slide cover is interconnected to the bolt and hammer sleeve, the return of the slide cover forward by the springs, also resets the bolt and hammer sleeve to their forward ready to fire position.

The field of the invention is that of oral pharmaceutical medicinal products or compositions, more particularly of the type of those comprising one or more active principles. The aim of the invention is to provide an improved oral medicinal product that can be administered in one or more daily doses, with modified release of active principle (in particular an active principle), for improving the prophylactic and therapeutic efficacy of such a medicinal product. This aim is achieved by means of the multimicrocapsular oral pharmaceutical form according to the invention in which the release of the AP is controlled by means of a double mechanism of triggering the release: “time triggering” and “pH triggering”. This medicinal product comprises microcapsules with modified release of active principle, each containing a core comprising the active principle and one or more swelling agents, and at least one coating making possible the modified release of the active principle.

A jaw release mechanism for locking pliers which utilize an over-center toggle locking mechanism and wherein the normally stationary upper jaw of the pliers is pivotally fastened to the main body of the pliers. This normally stationary upper jaw is releaseably retained in a normally stationary position relative to the main body of the pliers by a thumb actuated trigger release mechanism whereby the locked pliers may be safely released with the same hand which grasps and manipulates the pliers.

The invention relates to a method for releasing a biological sample from a solid matrix substantially without disintegration of biomolecules comtained in said biological sample by at least partially transferring the solid state of said matrix into a dissolved or liquid state by changing at least one physico-chemical property of the environment of said matrix.

A pivoting headrest assembly incorporated into a rear row vehicle seat including a base and a pivotally supported seatback. A first bracket is fixedly supported atop the seatback and exhibits a striker. A second bracket is pivotally supported to the first bracket in a biased direction away from the striker and includes a headrest bun support. A hook is supported upon the second bracket in a first biased direction engaging the striker. A release element associated with the second bracket is biased direction and which, upon being actuated in a second counter-biased direction, engages a projecting portion associated with the hook. A cable is secured at a first end to a fixed location associated with the seat and extends through a redirection location an offset distance from a pivot location of the seatback, the cable securing at a second end to the release element.

A jaw release mechanism for locking pliers which utilize an over-center toggle locking mechanism and wherein the normally stationary upper jaw of the pliers is pivotally fastened to the main body of the pliers. This normally stationary upper jaw is releaseably retained in a normally stationary position relative to the main body of the pliers by a thumb actuated trigger release mechanism whereby the locked pliers may be safely released with the same hand which grasps and manipulates the pliers.

A needle guard device mountable to a pre-filled syringe in its ready-to-fill state. The device includes a lock collar and a device shield biased to move relative to the lock collar. The lock collar interfaces with the syringe neck to attach the device to the syringe. A flexible member interconnects the lock collar and device shield. With the removal of a needle shield assembly comprising rigid and soft needle shields, the device shield is free to move proximally along the syringe neck. As the device moves proximally, rotation arms of the lock collar interact with angled cutouts in the device shield, causing the device shield to rotate relative to the lock collar disengaging one or more keys on the device shield from one or more keyways in the lock collar triggering the device shield to move from a first configuration in which the device shield is retractable to expose a syringe sharp to a second configuration in which the device shield is fixedly positioned to cover the syringe sharp.

An archery bow includes a riser and a pair of flexible limbs extending from the riser, each limb having a distal end. At least one string extends between the limb distal ends and is movable between a drawn position and a fired position. A drop-away arrow rest mounted to the riser is movable between a raised position and a lowered position. The arrow rest is biased to the lowered position and includes a trigger sear for maintaining the arrow rest in the raised position. A cable guard arm is attached to and extends from the riser. A trigger assembly is carried by the cable guard arm and associated with the trigger sear. A trigger release is carried by and slidable along the cable guard arm. The trigger release is coupled with at least one string. The trigger release engages the trigger assembly and thereby disengages the trigger sear upon movement of the at least one string from the drawn position to the fired position.