The invention discloses a building method of a 3D printing weaving integrated forming building, which comprises the following steps: selecting basic structural components, using finite element analysis after space modeling, combining stress cloud pictures, setting a judgment field, carrying out structural space optimization, obtaining a structural component framework, carrying out calculation analysis on the structural component framework, determining the knitting range and the knitting density of the wire according to the weak surface of the structure, determining the printing process and theknitting process according to the framework of the structural component and the knitting range and the knitting density of the wire, preparing 3D printing materials; processing 3D printing substrateand wire materials according to the printing process and the knitting process, one-time forming of the superposition after construction layer by layer, or connecting through a preset tenon construction segment after the segment is printed. The building method of a 3D printing and weaving integrated forming building has the advantages of high toughness, fatigue resistance, and long service life, and enables the various parts of the building to not only achieve different requirements of structural mechanics, but also achieve economic beauty and type art on the basis of safety and reliability.