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37 results about "Sex Hormone Binding Protein" patented technology
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Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to the two sex hormones: androgen and estrogen. Other steroid hormones such as progesterone, cortisol, and other corticosteroids are bound by transcortin.
Genistein modulated reduction of cardiovascular risk factors
InactiveUS20070207225A1Reducing cardiovascular risk factorReduce risk factorBiocideAnimal repellantsFasting glucoseFibrinogen
The disclosed methods and compositions for reducing cardiovascular risk factors in mammals generally includes using genistein to modulate various inflammatory and cardiovascular risk markers including: homocysteine, C-reactive protein, fibrinogen, sex hormone-binding globulin, fasting glucose, insulin, insulin resistance, and osteoprotegerin.
Owner:PRIMUS PHARM INC
Treatment of sex hormone binding globulin (SHBG) related diseases by inhibition of natural antisense transcript to shbg
ActiveUS20120277290A1Modulate its functionOrganic active ingredientsNervous disorderDiseasePhysiology
The present invention relates to antisense oligonucleotides that modulate the expression of and / or function of Sex Hormone Binding Globulin (SHBG), in particular, by targeting natural antisense polynucleotides of Sex Hormone Binding Globulin (SHBG). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of SHBG.
Owner:CURNA INC
Methods of improving screening, diagnosis and staging of prostate cancer using serum testosterone
InactiveUS20060211059A1Ultrasonic/sonic/infrasonic diagnosticsInfrasonic diagnosticsBiological bodySerum ige
The present invention provides methods of screening for, detecting or diagnosing prostate cancer in a subject by determining the level of prostate specific antigen (PSA), complexed PSA (cPSA), free PSA, B-PSA, PRO-PSA or HK2 in a biological sample from the subject and correcting this level for free / bioavailable serum testosterone, total testosterone or sex hormone binding globulin. The present invention further relates to identifying a subject at risk for developing prostate cancer or for determining the effectiveness of anti-cancer therapy in a subject having prostate cancer, or for detecting cancer recurrence by determining the level of prostate specific antigen (PSA), complexed PSA (cPSA), free PSA, B-PSA, PRO-PSA or HK2 in a biological sample from the subject and correcting this level for free or bioavailable serum testosterone, total testosterone or a testosterone bound protein, including but not limited to sex hormone binding globulin.
Owner:TANEJA SAMIR S
Molecular marking method for pig litter size
InactiveCN101768642AShorten the generation intervalSpeed up the selection processMicrobiological testing/measurementEnzyme digestionAnimal science
The present invention relates to a molecular marking method for pig litter size. The method comprises the steps of pig genome DNA extraction, exon 6 primer design of sex hormone binding globulin (SHBG) genes, amplification in vitro and genotype detection. The present invention first discovers pig SHBG genes, discovers the obvious relationship between the polymorphism of exon 6 and pig litter size, and develops a restriction fragment enzyme digestion polymorphism detection method for detecting exon 6 mutational sites. The method can be used for the auxiliary selection of litter size during pig breeding, can realize the early selection of parent pigs and even can accurately select parent pigs when the pigs are born. Generation interval is largely shortened, and selection progress is accelerated. The method has the advantages of simple operation, low condition requirements in polymerase chain reaction processes, short amplification fragment length (217bp), easy amplification, high amplification efficiency and accurate genotype judgement.
Owner:INST OF ANIMAL HUSBANDRY & VETERINARY MEDICINE ANHUI ACAD OF AGRI SCI
Application of protein and proteome in preparation of liver cirrhosis diagnostic reagent
InactiveCN102183661AHigh sensitivityBiological testingPIGMENT EPITHELIUM-DERIVED FACTORProtein markers
The invention relates to application of protein and proteome in preparation of a liver cirrhosis diagnostic reagent. The protein comprises Lumican, Tetranectin, Pro-platelet basic protein (PBP), Pigment epithelium-derived factor (PEDF), Insulin-like growth factor binding protein 3 (IGFbp-3), Sex hormone-binding globulin (SHBG), Thioredoxin and composition of parts in the liver cirrhosis diagnostic reagent. Multiple proteins related with health and disease states are identified and evaluated in large range by adopting a proteome technology, the screened biomarkers for identifying hepatitis and liver fibrosis are used for predicting the degree of hepatitis and liver fibrosis and can be used for preparing a kit for diagnosing liver cirrhosis and liver cirrhosis level, and the protein markers identify the sensitivity of liver cirrhosis and degree thereof; and by combining the optimal conditions of various protein markers, the sensitivity can reach 89 percent, the specificity reaches over 90 percent, and the sensitivity and the specificity are higher than those of any known detection method.
Owner:天津宝瑞生物技术有限公司
Chinese medicinal composition for kidney-yang deficiency and phlegm-retention type polycystic ovanian syndrome
ActiveCN102302659ADecreased androgen levelsIncrease ovulation rateHeavy metal active ingredientsAnthropod material medical ingredientsCaladiumObstetrics
The invention relates to a Chinese medicinal composition for a kidney-yang deficiency and phlegm-retention type polycystic ovary syndrome. The Chinese medicinal composition comprises the following medicinal materials of epimedium, caladium, semen psoraleae, sliced deerhorn, sea horse, tortoise plastron and the like, does not contain rhubarb and Chinese angelica. The Chinese medicinal composition can reduce the level of androgens and androgen receptors of polycystic ovanian syndrome (PCOS) patients, improve the level of sex hormone binding globulin, reduce the level of free testosterone, improve the level of in-vivo estrogens, improve the growth and development of follicles and improve the ovulation rate and pregnancy rate of patients.
Owner:上海泰坤堂中医医院有限公司
Method of birth control and hormone regulation
InactiveUS20070077269A1Avoid problemsReduce doseOrganic active ingredientsBiocideObstetricsSexual hormones
A method of birth control and hormone regulation comprises utilizing a vaginal ring worn continuously during each menstrual cycle. A vaginal ring delivers predetermined doses of progesterone and beta-estradiol. Beta-estradiol does not cause an increase in sex hormone binding globulin and thereby does not decrease a woman's levels of free testosterone and libido.
Owner:LES MEDECINS
Methods of determining levels of steroid fractions utilizing SHBG calculations
InactiveUS20100273275A1Accurate estimateReduce laborBiological testingImmunoassaysBinding siteLaws of thermodynamics
There are provided methods for assaying biological specimens for steroids (androgens and estrogens), Sex Hormone-Binding Globulin (SHBG) and Albumin in order to calculate the free and bioavailable steroid concentration based on the laws of mass action and association constants predicated on the identification that one molar equivalent of SHBG contains two molar equivalents of steroid binding sites.
Owner:B&C BIOTECH
Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers
The inventors have proposed a novel panel of human plasma protein biomarkers for diagnosing hepatic fibrosis and cirrhosis. Presently there is no reliable non-invasive way of assessing liver fibrosis. A 2D-PAGE based proteomics study was used to identify potential fibrosis biomarkers. Plasma from patients with hepatic cirrhosis induced by infection with the hepatitis C virus (HCV) were analysed. Several proteins associated with liver scarring and potentially also related to viral infection were identified. These proteins include 14-3-3 protein zeta / delta, adiponectin, afamin, alpha-1-antitrypsin, alpha-2-HS-glycoprotein, apolipoprotein C-III, apolipoprotein E, C4b-binding protein beta chain, intact / cleaved complement C3dg, corticosteroid-binding globulin, fibrinogen gamma chain, beta haptoglobin at pH 5.46-5.49, haptoglobin-related protein, hemopexin, immunoglobulin J chain, leucine-rich alpha-2-glycoprotein, lipid transfer inhibitor protein, retinol-binding protein 4, serum paraoxonase / arylesterase 1, sex hormone-binding globulin and zinc-alpha-2-glycoprotein. These biomarkers can be used in conjunction with polypeptides in WO / 2008 / 031051. The concentrations of these novel biomarkers can be determined using an immunoassay where the concentrations would reflect the extent of fibrosis. A fibrosis scoring scale for each of the novel biomarkers is proposed. The additive result from the scores of all the novel biomarkers would give a more reliable indication of the degree of fibrosis rather than examining individual biomarkers.
Owner:UNIV OF OXFORD
Method for using serum SHBG as serum markers of pulmonary tuberculosis patients and application thereof
ActiveCN105223364AReliable resultsComponent separationChemiluminescene/bioluminescenceMulti drug resistantMass spectrometric
The invention discloses a method for using serum SHBG (Sex hormone-binding globulin) as serum markers of pulmonary tuberculosis patients and an application thereof. The expression levels of the serum SHBG in serum of the smear negative pulmonary tuberculosis patients, the smear positive pulmonary tuberculosis patients and the multi-drug resistant pulmonary tuberculosis patients are obviously increased, detection can be carried out with the iTRAQ and MALDI-TOF / MS combined technology, mass spectrometric detection shows that the expression levels of five peptide fragments of the SHBG in the serum of the smear negative pulmonary tuberculosis patients, the smear positive pulmonary tuberculosis patients and the multi-drug resistant pulmonary tuberculosis patients are obviously higher than the expression levels in the serum of pneumonia patients and the normal, and ELISA and immunohistochemistry also verify that the SHBG is highly expressed in the serum and tissues of the pulmonary tuberculosis patients. The method and the application are suitable for auxiliary detection of pulmonary tuberculosis serum, pathogenesis researching and tuberculosis resisting drug development.
Owner:GUANGXI MEDICAL UNIVERSITY
Pharmaceutical composition for treating polycystic ovary syndrome (PCOS)
InactiveCN102302668ADecreased androgen levelsIncrease ovulation rateHeavy metal active ingredientsOrganic active ingredientsIn vivoPolycystic ovary
The invention provides a pharmaceutical composition for treating polycystic ovary syndrome (PCOS). The pharmaceutical composition consists of a traditional Chinese medicine composition and chemical drugs, wherein the traditional Chinese medicine composition comprises the medicinal materials such as anemarrhena, fritillary bulb, tortoise plastron, fleece-flower root, lilyturf root, hippocampus andthe like; and the chemical drugs comprise one or more compound molecules of dexamethasone, spirolactone, ethinyloestradiol, estradiol valerate, conjugated estrogen and pharmaceutically acceptable salt. The pharmaceutical composition has the advantages of reducing the level of androgens and androgen receptors of patients suffering from PCOS, improving the level of sex hormone-binding globulin (SHBG), lowering the level of free testosterone (F-TESTO), further raising the level of in-vivo estrogens, improving growth and development of follicles and increasing ovulation rate and pregnancy rate ofthe patients.
Owner:上海泰坤堂中医医院有限公司
Methods and compositions for diagnosis and prognosis of renal injury and renal failure
InactiveUS20130230871A1Easy to adaptDisease diagnosisBiological testingAbnormal macrophageInterleukin 5
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of Interleukin-5, Interleukin-6 receptor subunit beta, Tissue factor, Sex hormone-binding globulin, Alpha-2-macroglobulin, Apolipoprotein A-I, Calcitonin, Thrombopoietin, C-reactive protein, Intercellular adhesion molecule 3, Macrophage metalloelastase, Apolipoprotein B-100, and Fibrinogen as diagnostic and prognostic biomarkers in renal injuries.
Owner:ASTUTE MEDICAL
Traditional Chinese medicine composition for treating kidney-yin deficiency and phlegm-blood stasis polycystic ovary syndrome (PCOS)
InactiveCN102302669ADecreased androgen levelsIncrease ovulation rateFish material medical ingredientsSexual disorderYin deficiencyIn vivo
The invention provides a traditional Chinese medicine composition for treating kidney-yin deficiency and phlegm-blood stasis polycystic ovary syndrome (PCOS). The traditional Chinese medicine composition comprises the medicinal materials such as anemarrhena, fritillary bulb, tortoise plastron, radix polygoni multiflori preparata, lilyturf root, hippocampus and the like. The medicinal materials are cooperative with each other so as to realize the efficacies of nourishing kidney and clearing away heat and reducing phlegm and removing blood stasis. The traditional Chinese medicine composition has the advantages of reducing the level of androgens and androgen receptors of patients suffering from PCOS, improving the level of sex hormone-binding globulin (SHBG), lowering the level of free testosterone (F-TESTO), further raising the level of in-vivo estrogens, improving growth and development of follicles and increasing ovulation rate and pregnancy rate of the patients.
Owner:上海泰坤堂中医医院有限公司
Serum protein marker group for diagnosis of type 1 and type 2 diabetes mellitus
InactiveCN107024590AExpanded Blood Sample CollectionAccurate diagnosisDisease diagnosisBiological testingCholesterylester transfer proteinSerum ige
The invention relates to a serum protein marker group for diagnosis of type 1 and type 2 diabetes mellitus. The serum protein marker group is composed of the following serum protein markers: PZP, which has an Accession number of P20742, sex hormone binding globulin: SHBG, which has an Accession number of I3L145, C reactive protein: CRP, which has an Accession number of P02741, cholesteryl ester transfer protein: CETP, which has an Accession number of P11597, and a heparin cofactor 2: SERPIND1, which has an Accession number of P05546.
Owner:XINJIANG MEDICAL UNIV
Sex hormone binding globulin preservation solution and application thereof
ActiveCN108409852AStable structureBiologically active and stableAntibody mimetics/scaffoldsBiological testingSexual hormonesSURFACTANT BLEND
The invention discloses a sex hormone binding globulin preservation solution, a preparation method thereof and a detection agent and a kit for detecting the sex hormone binding globulin, and belongs to the technical field of in vitro diagnostic reagents. The sex hormone binding globulin preservation solution includes a buffer, a sex hormone, group IIA and / or IIB ions, a penetrating agent, an animal serum, a surfactant, and a protein stabilizer, wherein the concentration of the sex hormone in the preservation solution is 1-10 mu M, and the concentration of the Group IIA and / or IIB ions in the preservation solution is 10 to 60 mM. Both the detection agent and the kit contain the preservation solution. The sex hormone binding globulin preservation solution can stabilize the structure and biological activity of a sex hormone-binding globulin dimer dissolved in the preservation solution. The detection agent and the kit can ensure the detection accuracy of sex hormone binding globulin, and are convenient and quick.
Owner:SHENZHEN NEW INDS BIOMEDICAL ENG
Methods of determining levels of steroid fractions utilizing SHBG calculations
InactiveUS20060246511A1Measured rapidly and convenientlyAccurately determineBiological testingImmunoassaysBinding siteAlbumin
There are provided methods for assaying biological specimens for steroids (androgens and estrogens), Sex Hormone-Binding Globulin (SHBG) and Albumin in order to calculate the free and bioavailable steroid concentration based on the laws of mass action and association constants predicated on the identification that one molar equivalent of SHBG contains two molar equivalents of steroid binding sites.
Owner:B&C BIOTECH
Treatment of sex hormone binding globulin (SHBG) related diseases by inhibition of natural antisense transcript to shbg
ActiveUS20160046942A1Modulate its functionOrganic active ingredientsNervous disorderDiseasePhysiology
Owner:CURNA INC
Kit for determining content of sex hormone binding globulin and testing method of kit
InactiveCN108226515AHigh detection sensitivityImprove precisionChemiluminescene/bioluminescenceBiological testingFluorescein isothiocyanateFully automatic
The invention discloses a kit for determining the content of sex hormone binding globulin (SHBG) in human serum by adopting magnetic particle chemiluminescence. The kit comprises a calibrator, a quality control material, a resistance agent, a magnetic particle agent and a luminescent substrate, wherein the resistance agent is prepared from fluorescein isothiocyanate labeled sex hormone-binding globulin coating antibody and an alkaline phosphatase labeled sex hormone-binding globulin labeling antibody; and the magnetic particle agent is a conjugate of magnetic particles and goat-anti FITC. By adopting the kit provided by the invention, a chemiluminescence technology and immunomagnetic particles are combined, a nearly homogenous reaction system is provided; in addition, a one-step reaction mode is adopted, the detection sensitivity and the precision are greatly improved, the detection range is enlarged, the reaction time is greatly shortened, is shorter than 25min from starting to add asample to obtaining a detection result and is obviously faster than the time of a similar kit; and in addition, multiple samples can be determined on a fully automatic chemiluminescence apparatus, sothat high-flux rapid determination of the sex hormone-binding globulin is realized, the accuracy is high, the specificity is strong, and the precision and the detection efficiency are greatly improved.
Owner:TAIZHOU ZECEN BIOTECH CO LTD
Marker for statin treatment stratification in heart failure
ActiveUS20160169911A1Bioreactor/fermenter combinationsBiological substance pretreatmentsInterleukin 6Cvd risk
The present invention is directed to a method of identifying a patient having heart failure as likely to respond to a therapy comprising a statin. The method is based on measuring the level of at least one marker selected from GDF-15 (Growth Differentiation Factor 15), Urea, SHBG (Sex Hormone-Binding Globulin), Uric acid, PLGF (Placental Growth Factor), IL-6 (Interleukin-6), Transferrin, a cardiac Troponin, sFlt-1 (Soluble fms-like tyrosine kinase-1), Prealbumin, Ferritin, Osteopontin, sST2 (soluble ST2), and hsCRP (high sensitivity C-reactive protein) in a sample from a patient. Further envisaged is a method of predicting the risk of a patient to suffer from death or hospitalization, wherein said patient has heart failure and undergoes a therapy comprising a statin. The method is also based on the measurement of the level of at least one of the aforementioned markers.
Owner:ROCHE DIAGNOSTICS OPERATIONS INC
Detection marker for diabetic nephropathy
InactiveCN107144620AClear electrophoresis resultsImprove featuresMaterial analysis by electric/magnetic meansWNK4Antigen
The invention provides a detection marker for diabetic nephropathy. The detection marker for the diabetic nephropathy consists of 12 proteins: keratin 19, haptoglobin, apolipoprotein E, C-reactive protein, a platelet factor 4 precursor, a sex hormone binding globulin precursor, an immunoglobulin heavy chain Viiiregionhil, a complement component C4, keratin6l, a C-reactive protein precursor splicing isoform 1, serine / threonine protein kinase WNK4 and a CD 5 antigen. Compared with an existing detection method, the detection marker provided by the invention has the advantages of high specificity, sensitivity and accuracy, and can be used as a basis for diagnosing the diabetic nephropathy.
Owner:LANZHOU BAIYUAN GENE TECH
Preparation of double-index immunochromatography kit for detecting Adipo and SHBG
PendingCN113514634AEasy to operateMeet clinical testing requirementsDisease diagnosisImmobilized AntibodiesPhysiology
The invention belongs to the field of immunodetection, and particularly relates to a double-index immunochromatography kit for detecting adiponectin (Adipo) and sex hormone binding globulin (SHBG). The main component is an immunochromatography test strip, and the immunochromatography test strip is formed by sequentially pasting a sample pad, a binding pad, a nitrocellulose membrane and absorbent paper on a PVC base plate. Adipo antibody-microspheres and SHBG antibody-microspheres are adsorbed on the binding pad, an Adipo antibody is fixed on the nitrocellulose membrane to form a detection line 1 (T1 line), an SHBG antibody is fixed on the nitrocellulose membrane to form a detection line 2 (T2 line), and an anti-IgG antibody is fixed to form a quality control line (C line). The invention also discloses a process for coupling the Adipo antibody and the SHBG antibody with the microspheres. The Adipo / SHBG detection immunochromatography kit is used to determine the Adipo and SHBG concentrations in blood or other body fluids, and is used for early prediction of insulin resistance, type 2 diabetes mellitus and gestational diabetes mellitus occurrence risks.
Owner:武汉市朗典精医生物科技有限公司
Chinese medicinal composition for kidney-yang deficiency and phlegm-retention type polycystic ovanian syndrome
ActiveCN102302659BDecreased androgen levelsIncrease ovulation rateHeavy metal active ingredientsAnthropod material medical ingredientsObstetricsYang deficiency
The invention relates to a Chinese medicinal composition for a kidney-yang deficiency and phlegm-retention type polycystic ovary syndrome. The Chinese medicinal composition comprises the following medicinal materials of epimedium, caladium, semen psoraleae, sliced deerhorn, sea horse, tortoise plastron and the like, does not contain rhubarb and Chinese angelica. The Chinese medicinal composition can reduce the level of androgens and androgen receptors of polycystic ovanian syndrome (PCOS) patients, improve the level of sex hormone binding globulin, reduce the level of free testosterone, improve the level of in-vivo estrogens, improve the growth and development of follicles and improve the ovulation rate and pregnancy rate of patients.
Owner:上海泰坤堂中医医院有限公司
Biomarkers for predicting degree of weight loss in male subjects
InactiveUS20180136229A1Great degree of weight lossLower Level RequirementsHealth-index calculationMedical automated diagnosisBeta-2-Microglobulin ProteinOrganism
A method for predicting the degree of weight loss in male subject attainable by applying one or more dietary interventions to a subject, said method comprising determining the level of one or more biomarkers in one or more samples obtained from the subject, wherein the biomarkers are selected from sex hormone-binding globulin, beta-2-microglobulin and serum paraoxonase / arylesterase.
Owner:SOC DES PROD NESTLE SA
Serum shbg protein as a serum marker of pulmonary tuberculosis and its application
ActiveCN105223364BReliable resultsComponent separationChemiluminescene/bioluminescenceMulti drug resistantMass spectrometric
Owner:GUANGXI MEDICAL UNIVERSITY
Marker for statin treatment stratification in heart failure
Owner:ROCHE DIAGNOSTICS OPERATIONS INC
Biomarkers for predicting degree of weight loss in male subjects
A method for predicting the degree of weight loss in male subject attainable by applying one or more dietary interventions to a subject, said method comprising determining the level of one or more biomarkers in one or more samples obtained from the subject, wherein the biomarkers are selected from sex hormone-binding globulin, beta-2-microglobulin and serum paraoxonase / arylesterase.
Owner:SOC DES PROD NESTLE SA
Medicinal composition for high-androgen polycystic ovary syndrome
ActiveCN102274390BDecreased androgen levelsIncrease ovulation rateOrganic active ingredientsHeavy metal active ingredientsCaladiumIn vivo
The invention relates to a medicinal composition for a high-androgen polycystic ovary syndrome. The medicinal composition comprises a Chinese medicinal composition and a chemical medicament, wherein the Chinese medicinal composition comprises the following medicinal materials: epimedium, caladium, fructus psoraleae, sliced deerhorn, sea horse, tortoise plastron and the like, and does not contain rhubarb and Chinese angelica. The medicinal composition can reduce the level of androgen and androgen receptors of polycystic ovary syndrome (PCOS) patients, improve the level of sex hormone binding globulin, reduce the level of free testosterone, improve the level of in-vivo estrogen further, improve the growth and development of follicles, and improve the ovulation rate and pregnancy rate of thepatients.
Owner:上海泰坤堂中医医院有限公司
Pharmaceutical composition for treating polycystic ovary syndrome (PCOS)
InactiveCN102302668BDecreased androgen levelsIncrease ovulation rateHeavy metal active ingredientsOrganic active ingredientsIn vivoPolycystic ovary
Owner:上海泰坤堂中医医院有限公司
Treatment of sex hormone binding globulin (SHBG) related diseases by inhibition of natural antisense transcript to SHBG
The present invention relates to antisense oligonucleotides that modulate the expression of and / or function of Sex Hormone Binding Globulin (SHBG), in particular, by targeting natural antisense polynucleotides of Sex Hormone Binding Globulin (SHBG). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of SHBG.
Owner:CURNA INC
Sex hormone-binding globulin preservation solution and its application
ActiveCN108409852BStable structureBiologically active and stableAntibody mimetics/scaffoldsBiological testingDimerActive agent
The invention discloses a preservation solution of sex hormone-binding globulin, a preparation method thereof, a detection agent and a kit for detecting sex hormone-binding globulin, and belongs to the technical field of in vitro diagnostic reagents. The preservation solution includes a buffer, sex hormones, IIA and / or IIB family ions, osmotic agents, animal serum, surfactants and protein stabilizers, wherein the concentration of the sex hormones in the preservation solution is 1- 10 μM, the concentration of the group IIA and / or group IIB ions in the preservation solution is 10-60 mM. Both the detection agent and the kit contain the preservation solution of the present invention. The preservation solution of the sex hormone binding globulin of the present invention can keep the dimer structure and biological activity of the sex hormone binding globulin dissolved in the preservation solution stable. The detection agent and kit can ensure the detection accuracy of sex hormone binding globulin, and are convenient and fast.
Owner:SHENZHEN NEW INDS BIOMEDICAL ENG
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