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1576 results about "Photo acoustic" patented technology
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Method, system and apparatus for dark-field reflection-mode photoacoustic tomography
InactiveUS20060184042A1Enhance the imageMinimize interferenceCatheterDiagnostics using tomographyUltrasonic sensorAcoustic wave
The present invention provides a method, system and apparatus for reflection-mode microscopic photoacoustic imaging using dark-field illumination that can be used to characterize a target within a tissue by focusing one or more laser pulses onto a surface of the tissue so as to penetrate the tissue and illuminate the target, receiving acoustic or pressure waves induced in the target by the one or more laser pulses using one or more ultrasonic transducers that are focused on the target and recording the received acoustic or pressure waves so that a characterization of the target can be obtained. The target characterization may include an image, a composition or a structure of the target. The one or more laser pulses are focused with an optical assembly of lenses and / or mirrors that expands and then converges the one or more laser pulses towards the focal point of the ultrasonic transducer.
Owner:TEXAS A&M UNIVERSITY
System for measuring a biological parameter by means of photoacoustic interaction
InactiveUS6833540B2Ultrasonic/sonic/infrasonic diagnosticsMaterial analysis using sonic/ultrasonic/infrasonic wavesLight guideTransducer
A system for measuring a biological parameter, such as blood glucose, the system comprising the steps of directing laser pulses from a light guide into a body part consisting of soft tissue, such as the tip of a finger to produce a photoacoustic interaction. The resulting acoustic signal is detected by a transducer and analyzed to provide the desired parameter.
Owner:ABBOTT LAB INC
Method and apparatus for non-invasive measurement of living body characteristics by photoacoustics
A method and apparatus for non-invasive measurement of living body information comprises a light source configured to generate light containing a specific wavelength component, an irradiation unit configured to irradiate a subject with the light, and at least one acoustic signal detection unit including piezoelectric devices formed of a piezoelectric single crystal containing lead titanate and configured to detect an acoustic signal which is generated due to the energy of the irradiation light absorbed by a specific substance present in or on a subject.
Owner:TOSHIBA MEDICAL SYST CORP
Opto-acoustic imaging devices and methods
ActiveUS20080161696A1Improve accuracyFacilitate proper co-registrationUltrasonic/sonic/infrasonic diagnosticsCatheterLight beamPhotoacoustic imaging in biomedicine
In one aspect, the invention relates to a probe. The probe includes a sheath, a flexible, bi-directionally rotatable, optical subsystem positioned within the sheath, the optical subsystem comprising a transmission fiber, the optical subsystem capable of transmitting and collecting light of a predetermined range of wavelengths along a first beam having a predetermined beam size. The probe also includes an ultrasound subsystem, the ultrasound subsystem positioned within the sheath and adapted to propagate energy of a predetermined range of frequencies along a second beam having a second predetermined beam size, wherein a portion of the first and second beams overlap a region during a scan.
Owner:LIGHTLAB IMAGING
System and method for optoacoustic imaging
InactiveUS20070015992A1Scattering properties measurementsDiagnostics using tomographyPulse shaperElectromagnetic radiation
A system and method are described for optoacoustic imaging a structural or compositional characteristic of an biological object using a coherent, broad range frequency tunable, electromagnetic radiation source and a pulse shaper to generate a sequence of electromagnetic radiation excitation signals.
Owner:GENERAL ELECTRIC CO
Optical-acoustic imaging device
InactiveUS20080119739A1Reduce radiation exposureShorten operation timeMaterial analysis using sonic/ultrasonic/infrasonic wavesSubsonic/sonic/ultrasonic wave measurementGratingRadiation exposure
The present invention is a guide wire imaging device for vascular or non-vascular imaging utilizing optic acoustical methods, which device has a profile of less than 1 mm in diameter. The ultrasound imaging device of the invention comprises a single mode optical fiber with at least one Bragg grating, and a piezoelectric or piezo-ceramic jacket, which device may achieve omnidirectional (360°) imaging. The imaging guide wire of the invention can function as a guide wire for vascular interventions, can enable real time imaging during balloon inflation, and stent deployment, thus will provide clinical information that is not available when catheter-based imaging systems are used. The device of the invention may enable shortened total procedure times, including the fluoroscopy time, will also reduce radiation exposure to the patient and to the operator.
Owner:PHYZHON HEALTH INC
Non-invasive, in vivo substance measurement systems
Tissue substance measurement systems are arranged with highly specialized optical sources. Quantum cascade lasers are high power semiconductor lasers which are tiny in size and highly tunable with respect to wavelength. When deployed in non-invasive tissue substance measurement systems, quantum cascade lasers offer system advantages such as high accuracy, small size, convenience, efficiency, among others. These specialized semiconductors may be used with systems based upon photoacoustic principles. Systems may be formed of a plurality of quantum cascade laser in an optical source, mechanism to couple light into tissue, an acoustic detector and a signal processor. In some versions, user interfaces provide a reporting and feedback function to a user.
Owner:HEFTI JOHN +2
Solar panel theft preventing installation and anti-theft method thereof
InactiveCN101136129ALow costStrong reliabilityBurglar alarm by disturbance/breaking stretched cords/wiresCombined useEngineering
The solar cell board anti-theft device is jointed with a solar power supply system controller, which comprises a alarming-signal generation unit to detect position conditions of the solar cell board and generate a alarming-signal to the solar power-supply system controller while detecting the cell board far away from safety range, an alarming unit for receiving the instruction signals sent from the solar power-supply system controller to conduct local photo-acoustic alarming.
Owner:北京意科能源技术有限公司
System and method for monitoring photodynamic therapy
InactiveUS20080221647A1High electromagnetic contrastHighly sensitive detection and monitoringSurgeryCharacter and pattern recognitionPhotodynamic therapyUltrasonic sensor
A system and method for monitoring photodynamic therapy of a target tissue, where the target tissue contains a photosensitizing substance, include a first light source configured to deliver light to the target tissue, the first light source having a wavelength capable of exciting the photosensitizing substance. An ultrasonic transducer receives photoacoustic signals generated due to optical absorption of light energy by the target tissue, and a control unit in communication with the ultrasonic transducer reconstructs photoacoustic tomographic images from the received photoacoustic signals to provide an indication of optical energy deposition due to the photosensitizing substance in the target tissue.
Owner:RGT UNIV OF MICHIGAN
System and Method for Photoacoustic Guided Diffuse Optical Imaging
InactiveUS20080123083A1Ultrasonic/sonic/infrasonic diagnosticsScattering properties measurementsSonificationUltrasonic sensor
A system and method for photoacoustic guided diffuse optical imaging of a sample include at least one light source configured to deliver light to the sample, at least one ultrasonic transducer disposed adjacent to the sample for receiving photoacoustic signals generated due to optical absorption of the light by the sample, and at least one optical detector for receiving optical signals generated due to light scattered by the sample. A control system is provided in communication with the at least one light source, the ultrasonic transducer, and the optical detector for reconstructing photoacoustic images of the sample from the received photoacoustic signals and reconstructing optical images of the sample from the received optical signals. The priori anatomical information and spatially distributed optical parameters of biological tissues from the photoacoustic images employed in diffuse optical imaging may improve the accuracy of measurements and the reconstruction speed.
Owner:RGT UNIV OF MICHIGAN
Ultrasound guided optical coherence tomography, photoacoustic probe for biomedical imaging
ActiveUS20110098572A1High resolution imagingEasy accessUltrasonic/sonic/infrasonic diagnosticsCatheterDiagnostic Radiology ModalityHigh resolution imaging
An imaging probe for a biological sample includes an OCT probe and an ultrasound probe combined with the OCT probe in an integral probe package capable of providing by a single scanning operation images from the OCT probe and ultrasound probe to simultaneously provide integrated optical coherence tomography (OCT) and ultrasound imaging of the same biological sample. A method to provide high resolution imaging of biomedical tissue includes the steps of finding an area of interest using the guidance of ultrasound imaging, and obtaining an OCT image and once the area of interest is identified where the combination of the two imaging modalities yields high resolution OCT and deep penetration depth ultrasound imaging.
Owner:RGT UNIV OF CALIFORNIA
Laser Optoacoustic Ultrasonic Imaging System (LOUIS) and Methods of Use
ActiveUS20130190595A1Increase contrastImprove resolutionUltrasonic/sonic/infrasonic diagnosticsMedical imagingHelical computed tomographyContrast resolution
Provided herein are the systems, methods, components for a three-dimensional tomography system. The system is a dual-modality imaging system incorporates a laser ultrasonic system and a laser optoacoustic system. The dual-modality imaging system has means for generate tomographic images of a volume of interest in a subject body based on speed of sound, ultrasound attenuation and / or ultrasound backscattering and for generating optoacoustic tomographic images of distribution of the optical absorption coefficient in the subject body based on absorbed optical energy density or various quantitative parameters derivable therefrom. Also provided is a method for increasing contrast, resolution and accuracy of quantitative information obtained within a subject utilizing the dual-modality imaging system. The method comprises producing an image of an outline boundary of a volume of interest and generating spatially or temporally coregistered images based on speed of sound and / or ultrasonic attenuation and on absorbed optical energy within the outlined volume.
Owner:TOMOWAVE LAB INC
Method and system for non-invasive determination of blood-related parameters
ActiveUS20050101846A1Limited accuracyFacilitates non-invasive measurementMaterial analysis using sonic/ultrasonic/infrasonic wavesDiagnostics using pressureEngineeringElectromagnetic field
A method and system for measuring time variations of a response of a blood perfused fleshy medium to an external electromagnetic field is provided. The response of the medium to the external electromagnetic field can be a photo-acoustic signal, obtained in response to the exciting light, and / or impedance of the medium, in response to the applied ac electromagnetic field. Measurements of the time variations of the response of the medium are carried out when the condition of artificial kinetics is created and maintained over a certain time period by applying primary over-systolic pressure to a certain location at the medium with normal blood flow, so as to achieve a state of temporary blood flow cessation at the medium downstream of the certain location. When required, the control of the condition of the artificial kinetics can be further achieved by applying a perturbation of secondary pressure to the fleshy medium.
Owner:ORSENSE LTD
Machine learning approach to beamforming
An embodiment according to the present invention includes a method for a machine-learning based approach to the formation of ultrasound and photoacoustic images. The machine-learning approach is used to reduce or remove artifacts to create a new type of high-contrast, high-resolution, artifact-free image. The method of the present invention uses convolutional neural networks (CNNs) to determine target locations to replace the geometry-based beamforming that is currently used. The approach is extendable to any application where beamforming is required, such as radar or seismography.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE
In vivo port wine stain, burn and melanin depth determination using a photoacoustic probe
ActiveUS7322972B2Avoid introducingSurgical instrument detailsDiagnostic recording/measuringBurning tissueBurn tissue
A photoacoustic probe for port wine stain (PWS), burn and melanin depth measurements is comprised of optical fibers for laser light delivery and a piezoelectric element for acoustic detection. The probe induced and measured photoacoustic waves in acryl amide tissue phantoms and PWS skin in vivo. Acoustic waves were denoised using spline wavelet transforms, then deconvolved with the impulse response of the probe to yield initial subsurface pressure distributions in phantoms and skin. The waves were then analyzed for epidermal melanin concentration, using a photoacoustic melanin index (PAMI) related to the amount of laser energy absorbed by melanin. Propagation time of the photoacoustic wave was used to determine the depth of blood perfusion underlying necrotic, burned tissue. Thus, the photoacoustic probe can be used for determining PWS, burn and melanin depth for most patients receiving laser therapy.
Owner:RGT UNIV OF CALIFORNIA
Quartz-enhanced photoacoustic spectroscopy
InactiveUS20050117155A1Radiation pyrometryMaterial analysis using sonic/ultrasonic/infrasonic wavesTuning forkAbsorbed energy
Methods and apparatus for detecting photoacoustic signals in fluid media are described. The present invention differs from conventional photoacoustic spectroscopy in that rather than accumulating the absorbed energy in the fluid of a sample cell, the absorbed energy is accumulated in an acoustic detector or sensitive element. In a preferred embodiment, the acoustic detector comprises piezoelectric crystal quartz. The quartz is preferably in the shape of a tuning fork.
Owner:RICE UNIV
Photo-Acoustic Flow Meter
A photo-acoustic flow meter for use in dialysis is described, that uses an optical beam to generate an acoustic signal in the fluid for which the flow rate is to be measured. The phase angle of the acoustic signal changes when traversing upstream and when traversing downstream. The phase difference between the acoustic signals received upstream and downstream, compared with a reference source signal is measured, and it yields the flow rate of the fluid.
Owner:FRESENIUS MEDICAL CARE HLDG INC
Emboli detection in the brain using a transcranial doppler photoacoustic device capable of vasculature and perfusion measurement
InactiveUS20140194740A1Rapid determinationQuick classificationBlood flow measurement devicesOrgan movement/changes detectionBrain vasculatureTriage
A device, method, and system for detecting emboli in the brain is disclosed. A transcranial Doppler photoacoustic device transmits a first energy to a region of interest at an internal site of a subject to produce an image and blood flow velocities of a region of interest by outputting an optical excitation energy to said region of interest and heating said region, causing a transient thermoelastic expansion and produce a wideband ultrasonic emission. Detectors receive the wideband ultrasonic emission and then generate an image of said region of interest from said wideband ultrasonic emission. A Doppler ultrasound signal will also be deployed to image the region of interest. Doppler presents changes in velocity to map blood flow. Additionally, a dye can be given to visualize the brain vasculature and a perfusion measurement can be made in various regions of the brain along with the transcranial Doppler and the photoacoustic screening. Systems are taught using resultory medical data for better triage within an enhanced stroke ecosystem.
Owner:CEREBROSONICS L L C
Ultrasonic imaging device
InactiveUS20100249562A1Material analysis using sonic/ultrasonic/infrasonic wavesDiagnostics using lightPhotoacoustic microscopyDiagnostic Radiology Modality
Various embodiments of the present invention include systems and methods for multimodal functional imaging based upon photoacoustic and laser optical scanning microscopy. In particular, at least one embodiment of the present invention utilizes a contact lens in combination with an ultrasound transducer for purposes of acquiring photoacoustic microscopy data. Traditionally divergent imaging modalities such as confocal scanning laser opthalmoscopy and photoacoustic microscopy are combined within a single laser system. Functional imaging of biological samples can be utilized for various medical and biological purposes.
Owner:UMW RES FOUND INC +1
System and method for gas analysis using doubly resonant photoacoustic spectroscopy
ActiveUS20060123884A1Increase productionReduce equipment downtimeMaterial analysis using wave/particle radiationMaterial analysis using microwave meansGas analysisGas detector
A method for analyzing gas concentration using doubly resonant photoacoustic spectroscopy, and a doubly resonant photaoacoustic gas detector comprising: i) a continuous wave light beam whose wavelength coincides with an absorption wavelength of a gaseous analyte; ii) a closed path optical cavity having at least two reflective surfaces; iii) an acoustic resonator chamber contained within said optical cavity, and comprising an acoustic sensor for detecting sound waves generated by a gaseous analyte present within said chamber, the light beam passing sequentially into, through and out of said chamber, and being repeatedly reflected back and forth through said chamber, and being modulated at a frequency which is equal to or equal to one-half of an acoustic resonance frequency of said acoustic resonator chamber.
Owner:LI COR
Optical-acoustic imaging device
InactiveUS20040082844A1Shorten operation timeReduce radiation exposureMaterial analysis using sonic/ultrasonic/infrasonic wavesSubsonic/sonic/ultrasonic wave measurementGratingRadiation exposure
The present invention is a guide wire imaging device for vascular or non-vascular imaging utilizing optic acoustical methods, which device has a profile of less than 1 mm in diameter. The ultrasound imaging device of the invention comprises a single mode optical fiber with at least one Bragg grating, and a piezoelectric or piezo-ceramic jacket, which device may achieve omnidirectional (360°) imaging. The imaging guide wire of the invention can function as a guide wire for vascular interventions, can enable real time imaging during balloon inflation, and stent deployment, thus will provide clinical information that is not available when catheter-based imaging systems are used. The device of the invention may enable shortened total procedure times, including the fluoroscopy time, will also reduce radiation exposure to the patient and to the operator.
Owner:PHYZHON HEALTH INC
Imaging guidewire
An imaging guidewire that, in one embodiment, includes: (1) a hypotube forming an elongated main body having a distal end, (2) at least one multimode optical fiber integral with the hypotube and configured to carry laser light for ultrasonic excitation, (3) a single-mode optical fiber integral with the hypotube, having a reflective coating located on a distal end thereof and at the distal end of the elongated main body and configured to carry laser light for ultrasonic detection and (4) an imaging cap coupled to the elongated main body at the distal end and including a photoacoustic layer configured to receive the laser light from the at least one multimode optical fiber.
Owner:TOTAL WIRE CORP
Low-Power Fast Infrared Gas Sensor, Hand Held Gas Leak Detector, and Gas Monitor Utilizing Absorptive-Photo-Acoustic Detection
InactiveUS20080277586A1Low possible costLow costDetection of fluid at leakage pointRadiation pyrometryHand heldEngineering
A gas sensor for sensing the presence of a gas includes an IR source, a microphone, a reference gas substantially similar to the gas to be detected, a reference body defining a reference chamber therein, the reference chamber having a pressure port coupled to the microphone, and a broad-band optical window through which at least IR wavelengths corresponding to absorption peaks of the predetermined gas may pass. The window is disposed between the IR source and reference chamber. The reference gas is contained within the reference chamber between the optical window and the microphone. The sensor can be included in a hand-held gas detection instrument having power supply, an outer shell, a circuit board assembly including sensor circuitry, a suction pump, actuation controls and status indicators. A probe defining a lumen therethrough supplies the sample gas.
Owner:CARDINALE DENNIS
Ultrasonic photoacoustic imaging apparatus and operation method of the same
InactiveUS20110319743A1Reduce signal strengthUltrasonic/sonic/infrasonic diagnosticsInfrasonic diagnosticsSonificationPhase shifted
An ultrasonic photoacoustic imaging apparatus which includes a probe incorporating an array transducer having a plurality of transducers and an acoustic image generation unit that generates, based on a mixed signal obtained by converting an acoustic wave, in which an ultrasonic wave and a photoacoustic wave are mixed and making use of a difference between phase shift aspect of electrical signals of the ultrasonic waves from the same reflection source in the inside of the subject and phase shift aspect of electrical signals of the photoacoustic waves from the same generation source in the inside of the subject, an electrical signal reflecting the ultrasonic wave and an electrical signal reflecting the photoacoustic wave, and generates an ultrasonic image based on the electrical signal reflecting the ultrasonic wave and a photoacoustic image based on the electrical signal reflecting the photoacoustic wave.
Owner:FUJIFILM CORP
Low-cost device for c-scan photoacoustic imaging
ActiveUS20100016717A1Small sizeLow costUltrasonic/sonic/infrasonic diagnosticsWave based measurement systemsSensor arraySonification
The prostate gland or other region of interest is stimulated with laser light, resulting in ultrasound waves (photoacoustic effect) which are focused by an acoustic lens and captured by a specific 1- or 2D sensor array and subsequently displayed as a C-scan on a computer screen. The amplitude of the ultrasound waves generated by laser stimulation is proportional to the optical absorption of the tissue element at that spatial location. Variability in tissue absorption results in C-scan image contrast. The photoacoustic imaging is combined with an ultrasound C-scan image produced with a plane ultrasound wave applied to the region of interest.
Owner:ROCHESTER INSTITUTE OF TECHNOLOGY
Photoacoustic tracking and registration in interventional ultrasound
ActiveUS20150031990A1Organ movement/changes detectionSurgical navigation systemsSonificationElectromagnetic radiation
An intraoperative registration and tracking system includes an optical source configured to illuminate tissue intraoperatively with electromagnetic radiation at a substantially localized spot so as to provide a photoacoustic source at the substantially localize spot, an optical imaging system configured to form an optical image of at least a portion of the tissue and to detect and determine a position of the substantially localized spot in the optical image, an ultrasound imaging system configured to form an ultrasound image of at least a portion of the tissue and to detect and determine a position of the substantially localized spot in the ultrasound image, and a registration system configured to determine a coordinate transformation that registers the optical image with the ultrasound image based at least partially on a correspondence of the spot in the optical image with the spot in the ultrasound image.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE
Mid-IR laser instrument for analyzing a gaseous sample and method for using the same
InactiveUS20070064748A1Wide tunabilityRapidly tuned SLM idlerPolycrystalline material growthDiffusion/dopingNoseMicrometer
An optical nose for detecting the presence of molecular contaminants in gaseous samples utilizes a tunable seed laser output in conjunction with a pulsed reference laser output to generate a mid-range IR laser output in the 2 to 20 micrometer range for use as a discriminating light source in a photo-acoustic gas analyzer.
Owner:UNIVERSITY OF ALABAMA
Photoacoustic imaging devices and methods of imaging
ActiveUS20100268058A1Improve image contrastFast processingUltrasonic/sonic/infrasonic diagnosticsCatheterFiberUltrasonic sensor
A photoacoustic medical imaging device may include a substrate, an array of ultrasonic transducers on the substrate, at least one groove etched on the substrate, at least one optical fiber, and at least one facet. Each optical fiber is disposed in one of the grooves. Each facet is etched in one of the grooves and coated with a layer of metal having high infrared reflectivity. Each optical fiber is configured to guide infrared light from a light source through the fiber and toward the respective facet. The facet is configured to reflect the infrared light toward a target.
Owner:STC UNM
Disposable couplings for biometric instruments
InactiveUS20050090725A1Improve energy transferGood of laser lightUltrasonic/sonic/infrasonic diagnosticsDiagnostics using lightAcoustic energyOpto electronic
Photoacoustic measurement system are configured with a special view towards efficient coupling of optical and acoustic energy between respective transducers and a tissue test site. In particular, a disposable substrate provides support for advanced optical paths including, for example, windows, lenses, and index matching gels or fluids. In addition, substrates may also accommodate arrays of coupling sites corresponding to a plurality of acoustic detectors spatially separated. These substrates may additionally include means to affix and secure the device to a measurement head having optoelectronic and electromechanical transducers therein. Further, these substrates include mechanisms which help to affix the substrates to test sites in stabile and secure fashion.
Owner:PAGE JOSEPH +1
Photoacoustic imaging devices and methods of making and using the same
ActiveUS20110190617A1Material analysis using sonic/ultrasonic/infrasonic wavesMaterial analysis by optical meansUltrasonic sensorTransducer
A photoacoustic imaging device includes an array of light sources configured and arranged to illuminate a target region and an array of ultrasonic transducers between the array of light sources and the target region. The array of transducers may be fixedly coupled to the array of light sources, and the array of ultrasonic transducers may be configured and arranged to receive ultrasound transmissions from the target region.
Owner:STC UNM
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