114 results about "Microbial contaminants" patented technology

A modular filter system is provided with one or more modules that can be interchangeable, depending upon the specific application or specific health or environmental issue presented. Disclosed combinations can include one or more of any of the following modules in any relative position to one another: (a) a microbiological contaminant mitigation module, preferably in the form of an inverted u-shaped hollow fiber filter module wherein the fibers have ends potted on the downstream side and that consists essentially of hydrophilic fibers for water filtration with a small amount of hydrophobic fibers for venting of entrapped air; (b) a first chemical mitigation module, preferably in the form of an adsorption module comprising carbon or the combination of carbon and a deionization resin; and (c) a second chemical mitigation module, preferably in the form of a deionization resin module. Modules including a carbon bed or a resin bed may be equipped with a pair of hydrophobic foam bed restraints that apply opposing axial pressure to the bed in all operating conditions.

The invention provides methods and compositions for the detection and / or quantification of a microbial contaminant, for example, a bacterial endotoxin or a glucan, in a sample. In particular, the invention provides a test cartridge useful in the practice of hemocyte lysate-based assays for the detection and / or quantification of a microbial contaminant in a sample. In addition, the invention provides methods of making and using such cartridges. In addition, the invention provides a rapid, sensitive, multi-step kinetic hemocyte lysate-based assay for the detection and / or quantification of a microbial contaminant in a sample. In addition, the invention provides a glucan-specific lysate that can be used in a variety of assay formats, including, for example, a test cartridge, optionally configured to perform a kinetic assay.

A portable, lightweight, easy-to-carry, reusable, durable, and environmentally-friendly assembly for sterilizing contaminated equipment using conditions of a chemical sterilant, heat, and humidity generated in situ without requiring external electricity, fuels, or other exogenous energy sources for operation. The carry assembly includes a plastic carry-case or insulated aluminum pressure vessel having an inner chamber for accepting microbiologically contaminated objects, a vessel disposed in the chamber for serving as a reaction chamber and / or boiler, a chemical combination which upon mixing generates at least minimally sufficient conditions of the sterilant, heat, and humidity to effect sterilization of the objects, and outlet valves mounted on the carry-case for controllably venting pressures above ambient air pressure.

Biological waste such as food, organic or other biologically-derived waste is converted into shelf-stable and health-safe invertebrate feed. The method for converting includes pre-treating waste by fragmenting, reducing microbial contaminants, optionally amending with components that optimize fermentation, inoculating with microorganisms and mixing. Fermentation takes place in a bioreactor and produces fermentation leachate and solid fermentate. In the post-treatment steps, the solid fermentate is separated from the fermentation leachate. The solid fermentate is ground, dewatered and milled. The solid fermentate can be used as an invertebrate feed with or without further processing.

A method for obtaining a fermentation product from a sugar hydrolysate obtained from a feedstock containing hemicellulose, by (i) removing suspended fiber solids from said sugar hydrolysate to obtain a clarified sugar solution; (ii) fermenting xylose in the clarified sugar solution in a fermentation reaction with yeast to produce a fermentation broth comprising the fermentation product; (iii) separating the yeast from the fermentation broth to produce a yeast slurry; (vi) treating the yeast slurry thus obtained with an oxidant to kill microbial contaminants, thereby an oxidant-treated yeast slurry; (v) re-introducing at least a portion of the oxidant-treated yeast back to step (ii) to increase the concentration of yeast in said fermentation reaction; and (vi) recovering the fermentation product.

Particular aspects provide a method of sampling, testing and validating test lots (e.g., single-unit production lots), comprising: assembling a plurality of product portions from each of a plurality of test lots and combining the collected product portions to provide a corresponding set of test lot samples (wherein each test lot sample is attributed to a particular corresponding test lot); enriching the set of test lot samples; removing equal portions of each enriched sample, and combining the removed portions to provide a modular composite sample; and testing of the modular composite sample for the target agent / organism, wherein where such testing is positive, individual test lots may nonetheless yet be validated by further testing of a respective enriched test lot sample and obtaining a negative test result. The methods have broad utility for monitoring all sort of test lots (e.g., environmental lots, production lots, pharmaceutical lots, etc.) and for efficiently affecting informed, targeted remedial measures.

A disposable folding type sanitary toilet for pets includes a folding type receiving unit configured in the form of a box having a receiving space. A wall of the box is configured to fold such that the volume of the receiving unit is adjusted, thereby allowing the sanitary toilet to be easily stored and carried. The sanitary toilet further includes a case unit for containing the bottom of the receiving unit and protecting the bottom, top, and sides of the receiving unit. The receiving unit includes a top plate, a wall unit connected to the top plate, the wall unit having horizontal folds formed at its exterior for adjusting the vertical height of the wall unit, and a lower receiving part coupled to the bottom of the wall unit and having a receiving space. An attached filter may be deployed during closure to inhibit discharge of dust and / or microbial contaminants.

Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions are provided. The methods and compositions employ modified bioburden testing and the detection of peptidoglycan. A novel cause of aseptic peritonitis is provided—aseptic peritonitis associated with gram positive microbial contamination of a dialysis solution. Peptidoglycan is a major component of a gram positive bacterial cell wall and thus can serve as a marker for gram positive bacteria. In this regard, testing for peptidoglycans can be utilized to effectively prevent peritonitis in patients that use the peritoneal dialysis solutions, such as peritoneal dialysis solutions that contain a glucose polymer including an icodextrin and the like.

The invention provides a dual-membrane processing system and method for micro-polluted raw water, relating to a processing system and method for drinkable water and aiming to solve problems that the prior drinkable water processing technology cannot ensure biological safety of water quality, can hardly control contaminants of biological origin such as bacteria, has complicated process and causes unstable effluent quality. Most of colloids and granular materials in raw water are removed by using a micro-filtration membrane module and micro-organic contaminants such as bacteria are completely entrapped by using an ultra-filtration membrane module so as to realize water processing by using two membranes. The method comprises the following steps: raw water and water processing medicines are mixed in a mixing pool and then the mixture is added in a micro-filtration membrane separating pond to completely react, the products of reaction are filtered by the micro-filtration membrane module to obtain filtered water, and then the filtered water is added in the ultra-filtration membrane separating pond to be filtered by the ultra-filtration membrane module to obtain clean water, and the clean water is added in a clean water tank to be sterilized by a sterilant to obtain drinkable water. The invention is used for production of drinkable water with micro-polluted surface water as a water source and water quality safeguard.

Provided are compositions and methods useful to the determination of whether a microbial contaminant is present in a biological therapeutic production process. Specifically, an artificial positive amplification control plasmid and unique quantitative PCR detection probe are provided, which enables the rapid and real-time detection of a false positive result.

The present invention generally relates to a device for obtaining samples of meat during commercial meat production. More specifically, embodiments of the present invention provide for an automated, hand held device used to rapidly obtain samples of meat that are of essentially uniform size in order to test for the presence of microbiological contaminants in such meat, as well as methods of using the device. The device can be used to comply with laws and regulations concerning the testing of meat for microbial contamination during commercial meat production. The device is also lightweight and ergonomically constructed so that it may be operated by a single individual.

This sterile packing includes: a container (2) for holding the at least one object (5) to be sterilized and having an inlet opening (11 ) and a discharge opening (13) via which the at least one object (5) may pass into and out of the container (2), the container (2) comprising a rigid part (6) having a bored peripheral wall with a multitude of small holes (10) having dimensions lower than those of the the at least one object (5), and a non-rigid part (7) in a material porous to the sterilizing fluid and non-porous to microbial contamination, the non-rigid part (7) being able to contain the rigid part (6) and to be sealed thereon; and - at least one envelope (4) made in a flexible and airtight material, which is vacuum sealing fitted on the container (2).