44 results about "Light dose" patented technology

Process and apparatus for the formation of patterns in a photosensitive resin layer or photoresist by continuous laser irradiation, application to the production of microtip emissive cathode electron sources and flat display screens. Formation takes place of non-mutually interfering elementary light beams (41), there is at least one relative translation at constant light power and speed of said beams with respect to the layer in order to irradiate lines thereof, each line receiving a light dose lower than that necessary for the development of the resin, a relative rotation of all the beams with respect to the layer takes place, the translation is recommenced in order to irradiate other lines, each line receiving a light dose complimentary to the preceding dose and the resin is developed.

A disinfecting conveyor system utilizes ultraviolet light to disinfect a product as it passes through an enclosure on a conveyor. A UV light sensor provides feedback to a control system that can change the amount of UV light exposure, speed of conveyor, and disinfection reaction. A UV light sensor may be a coupled to the conveyor and the UV light intensity and time of exposure within the enclosure may be used to calculate a UV light dose. A user of the system may input a required UV light dose or the type of product to be disinfected and the control system may automatically control the speed of the conveyor and/or the UV light intensity to provide the required UV dose. The system may utilize an air filtration and/or cooling system to provide a flow of clean and cool process air to the enclosure to maintain a temperature that is below a threshold temperature.

Described herein are embodiments of a method to control energy dose output from a laser-produced plasma extreme ultraviolet light system by adjusting timing of fired laser beam pulses. During stroboscopic firing, pulses are timed to lase droplets until a dose target of EUV has been achieved. Once accumulated EUV reaches the dose target, pulses are timed so as to not lase droplets during the remainder of the packet, and thereby prevent additional EUV light generation during those portions of the packet. In a continuous burst mode, pulses are timed to irradiate droplets until accumulated burst error meets or exceeds a threshold burst error. If accumulated burst error meets or exceeds the threshold burst error, a next pulse is timed to not irradiate a next droplet. Thus, the embodiments described herein manipulate pulse timing to obtain a constant desired dose target that can more precisely match downstream dosing requirements.

A method of fabricating semiconductor devices begins by providing or fabricating a device structure that includes a semiconductor material and a plurality of gate structures formed overlying the semiconductor material. The method continues by creating light dose extension implants in the semiconductor material by bombarding the device structure with ions at a non-tilted angle relative to an exposed surface of the semiconductor material. During this step, the plurality of gate structures are used as a first implantation mask. The method continues by forming a patterned mask overlying the semiconductor material, the patterned mask being arranged to protect shared drain regions of the semiconductor material and to leave shared source regions of the semiconductor material substantially exposed. Thereafter, the method creates heavy dose extension implants and/or halo implants in the semiconductor material by bombarding the device structure with ions at a tilted angle relative to the exposed surface of the semiconductor material, and toward the plurality of gate structures. During this step, the plurality of gate structures and the patterned mask are used as a second implantation mask.

A Photodynamic Therapy (PDT) system with an elongated interventional device (IDV) with a bundle of optical fibers (F1, F2, F3) forming respective light exit ports which can be individually accessed. The bundle has an optical shape sensing fiber (OSS), e.g. including Fiber Bragg Gratings, arranged for sensing position and orientation (P_O) of the light exit ports. A processor executes a control algorithm which generate a light dose signal (LDS) to allow generation of light outputs (LD1, LD2, LD3) to the plurality of optical fibers (F1, F2, F3) accordingly. The control algorithm generates the light dose signal (LDS) in response to the determined position and orientation of the light exit ports (P_O), and three-dimensional body anatomy image information obtained by a first image modality (I1), e.g. X-ray, MRI, CT, ultrasound, or PET-CT. This combination allows precise application of a light dose distribution for PDT treatment of a tumor with a minimal destruction of connective tissue. In embodiments, the control algorithm takes image information regarding distribution of a photo sensitizer in the body tissue (I2) as input. The control algorithm may further take into account image information regarding a concentration of oxygen in the body tissue (I3). Both of such inputs allow a more precise PDT light application.

The invention discloses a pure oxygen- photodynamic composite skin therapeutic instrument which comprises a main body, an irradiator and a spiral arm connected between the main body and the irradiator, wherein a light source circuit board is arranged on the irradiator, and a light-emitting element is fixedly arranged on the light source circuit board; and an oxygen spray nozzle unit is further arranged on the irradiator, an oxygen making device is arranged on the main body, and the oxygen spray nozzle unit is connected to the oxygen making device through a pipeline. The tissue oxygen concentration can be increased and the photodynamic therapeutic effect can be significantly improved by adopting a design of the oxygen making device and the oxygen spray nozzle unit; by adopting the design of a light wavelength feedback module and a light dose feedback module, the pure oxygen-photodynamic composite skin therapeutic instrument can ensure that an irradiated region can obtain the same light dose so that the photodynamic therapeutic effect can be improved; and as the light-emitting element is a composite light-emitting diode with three wavelengths, the single wavelength or the two wavelengths or the three wavelengths can be selected for performing combined therapy according to actual needs.

The invention discloses a super-resolution imaging method and system by utilizing square lattice structure light illumination, and the method mainly comprises the following steps: forming a lattice structure light field on a sample plane, and carrying out the phase shift through controlling a light field modulation device; acquiring a fluorescence image illuminated by the lattice structure light;and utilizing a frequency domain reconstruction algorithm to obtain a super-resolution image. Compared with common striped structured light, the square lattice structure light has lower light dose under the same peak intensity, the phototoxicity of the system can be greatly reduced, living cells can be observed for a longer time, and in addition, only phase shift needs to be carried out on the illumination pattern in the imaging process without rotation, so that polarization control in the imaging process is simplified to a great extent, the complexity of the system can be reduced, and the construction cost of the system is effectively reduced.

The invention discloses a homogeneous creatine kinase chemiluminiscence detection reagent and a preparation method thereof. The method comprises steps of adopting gold nanoparticles, adding a water-soluble photosensitizer into the gold nanoparticles and acquiring a nanogold-photosensitizer compound, coupling the nanogold-photosensitizer compound with a creatine kinase monoclonal antibody, and generating electrostatic adsorption between the two under the isoelectric point environment condition of the creatine kinase monoclonal antibody through the charge property of the nanogold particles, so that the creatine kinase monoclonal antibody is coupled to the surfaces of the nanogold particles. The homogeneous creatine kinase chemiluminiscence detection reagent is obtained according to the preparation method disclosed by the invention, the utilization rate of the photosensitizer is increased, the production process is simplified, the production cost is reduced, a sandwich method detection principle is adopted to detect a detected object in use, the effective light dose of irradiation is increased, more photosensitizers are activated, a stronger photosensitive effect is generated, the difference between the excitation light wavelength and the emission wavelength is increased, and the detection identification degree is improved.

The invention discloses a therapy method based on a photodynamic therapy system, and the photodynamic therapy system. The method comprises the following steps of: obtaining a fluorescence image generated when a photosensitizer on a tissue to be treated is irradiated; calculating the fluorescence image according to a fluorescence image processing algorithm, and determining the overexposure area andthe underexposed area of the fluorescence image; analyzing the overexposure area and the underexposed area of the fluorescence image according to a pre-set convolutional neural network model, and determining excitation light doses required by various points of the fluorescence image; and performing therapy by generating the therapy light intensity according to the excitation light doses requiredby various points of the fluorescence image. By implementation of the therapy method based on the photodynamic therapy system, and the photodynamic therapy system in the invention, the fluorescence image, the overexposure area and the underexposed area of which are marked, can be input into the pre-set convolutional neural network model; the excitation light parameters required by various points of the best fluorescence image can be determined and obtained according to output of the pre-set convolutional neural network model; therefore, optimal imaging is obtained by the minimum exposure time;and fluorescent bleach due to the excessive exposure time of the photosensitizer is reduced.

The invention discloses a homogeneous method heart-type fatty acid binding protein chemiluminiscence detection reagent and a preparation method thereof. The method comprises steps of adopting gold nanoparticles, adding a water-soluble photosensitizer into the gold nanoparticles, acquiring a nanogold-photosensitizer compound, coupling the nanogold-photosensitizer compound with a heart-type fatty acid binding protein monoclonal antibody, generating electrostatic adsorption between the two under the isoelectric point environment condition of the heart-type fatty acid binding protein monoclonal antibody through the charge property of the gold nanoparticles, so that the heart-type fatty acid binding protein monoclonal antibody is coupled to the surfaces of the gold nanoparticles. The homogeneous method heart-type fatty acid binding protein chemiluminiscence detection reagent is obtained according to the preparation method disclosed by the invention; the utilization rate of the photosensitizer is increased, the production process is simplified, the production cost is reduced, a sandwich method detection principle is adopted to detect a detected object in use, the effective light dose ofirradiation is increased, more photosensitizers are activated, a stronger photosensitive effect is generated, the difference between the excitation light wavelength and the emission wavelength is increased, and the detection identification degree is improved.

In the thin film transistor, an active layer includes a channel region, a first doped region, and second doped region. Insulation layer of grid pole formed on the active layer includes at least a central region, a shelter region and an extended region. The central region covers the channel region. The shelter region positioned at periphery of the central region covers first doped region. The extended region is positioned at periphery of the shelter region covers second doped region. A grid layer is formed on grid insulation layer. The grid layer covering the central region exposes the shelter region and the extended region. Thickness of the shelter region of grid insulation layer is thicker than thickness of the extended region of grid insulation layer.