44 results about "Kidney pelvis" patented technology

The present invention provides a novel cancer marker that is useful in the diagnosis of urothelial cancer. The present invention uses ubiquilin 2 as a cancer marker for urothelial cancer (renal pelvis cancer, ureteral cancer, and bladder cancer). Detection of ubiquilin 2 in a urine sample allows easy and accurate diagnosis of a possibility of urothelial cancer. The present invention is also applicable to the diagnosis of squamous cancer (esophageal cancer, cervical cancer, etc.).

The invention relates to methods for locally delivering a chemotherapeutic agent to an upper tract urothelial carcinoma (UTUC). The methods involve placing a balloon catheter that has a working channel and a balloon into the ureter / renal pelvis via retrograde or antegrade ureteral access; inflating the catheter balloon to temporarily obstruct the ureter; infusing (instilling) a liposomal formulation that includes a chemotherapeutic agent into the working channel of the catheter; and allowing the infused liposomal formulation to dwell in the ureter and / or renal pelvis for a time sufficient to allow at least a portion of the liposomal formulation to adhere to the urothelial wall. In the methods of the invention, at least a portion of the infused chemotherapeutic-agent formulation adheres tothe urothelial wall while it is instilled and dwells in the ureter and / or renal pelvis. The disclosed methods can be performed as an adjuvant therapy to other methods of treating UTUC, such as ureteroscopic ablation or resection of the tumor.

There is provided a method for controlling a flow of urine in the urinary passageway of a patient's urethra, ureter, renal pelvis or bladder. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the urinary tissue wall) at least one portion of the urinary tissue wall to influence the flow in the urinary passageway, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the flow in the urinary passageway. The method can be used for restricting or stopping the flow in the urinary passageway of a urinary incontinent patient, or for actively moving the urine in the urinary passageway, with a low risk of injuring the urethra, ureter, renal pelvis or bladder.

The invention relates to a ureteral rapid liquid-gas expansion pipeline suite and a using method thereof. The ureteral rapid liquid-gas expansion pipeline suite comprises a first ureteral catheter and a second ureteral catheter. The ureter is pre-expanded through the first ureteral catheter, the first ureteral catheter is not suitable for remaining in the ureter for a long time due to the fact that a pelvis drainage channel is removed from the first ureteral catheter, the problem that the pressure in the kidney of the working side is increased is solved, and therefore the first ureteral catheter is only prepared for short-time expansion and preliminary expansion of the ureter; and after the diameter of the ureter is increased, the second ureteral catheter can be more conveniently placed for long-time expansion, the expansion time is several hours or ten hours or longer, the ureteral expansion effect and safety are greatly improved, the placing success rate of the second ureteral catheter is increased, then the operation success rate of a flexible ureteroscope is increased, the process requirement and price of the flexible ureteroscope are reduced, the performance of the flexible ureteroscope is improved, the diameter of a water flow channel is increased, and the safety and effect of the flexible ureteroscope are rapidly improved.

The invention discloses a ureteral stent special for kidney transplantation. The ureteral stent comprises a stent body, a first curly tube, a tube opening, an intercepting tube, a second curly tube, aguide tube, a bent guide wire, a through hole, a protrusion, an intercepting tube wall, a limiting block, a rubber ring, a round hole, an intercepting cavity, a water blocking ball, a mounting cap and an elastic supporting body. The bent guide wire is made of a plastic material, so that the second coiled tube can be stably fixed in a renal pelvis of a transplanted kidney, the protrusions are allrubber protrusions and can block calculus particles, the stent body is made of a medical silica gel material, the water blocking ball is matched with the round hole, and the stent body is made of a medical silica gel material. The diameter of the water blocking ball is larger than the maximum diameter of the round hole, the phenomenon of urine backflow is prevented conveniently, the smooth layer is arranged in the stent body, a smooth inner surface is provided for the ureteral stent conveniently, smooth passing of fluid is facilitated, and the smoothness of an inner cavity of a tube body of the ureteral stent is improved.

The invention discloses a method for automatically evaluating difficulty of kidney tumor enucleation based on CT (computed tomography) images, which comprises the following steps: based on artificial intelligence and image analysis technologies, segmenting an abdominal wall, a kidney and a kidney tumor at the same time by establishing a deep network model, automatically calculating an MAP score and an R.E.N.A.L score by utilizing relevance among the tumor, a renal pelvis, the kidney and the abdominal wall, and automatically evaluating the difficulty of the kidney tumor enucleation based on the CT images. Therefore, the difficulty of the kidney tumor enucleation is reasonably and effectively evaluated; the method has the advantages of time and labor saving and high evaluation accuracy and reliability.

Drug delivery devices and systems, are provided for delivery of a drug into the upper urinary tract of patients in need thereof. The drug delivery devices (100) may be deployed directly into the renal pelvis via a patient's ureter, bladder, and urethra, and the drug delivery devices can be wholly retained therein for local continuous, controlled release of a drug over an extended period.

A method for preventing, treating and / or improving a prostatic disease or disorder associated with epithelial hyperplasia and / or fibrosis, comprising: administering an effective amount of a multikinase inhibitor to a subject in need thereof, wherein the multikinase inhibitor has a certain spectrum of kinase inhibitory activity. The multikinase inhibitor is sunitinib, regorafenib, ponatinib, pazopanib, nintedanib and / or lenvatinib. The prostatic disease or disorder is selected from the group consisting of benign prostate hyperplasia and its associated lower urinary tract symptoms, fibrosis of ureters and renal pelvis, prostate adenoma, and prostatic intraepithelial neoplasia in animals and humans.

The invention relates to the technical field of medical instruments, more specifically to a ureteral stent tube. The ureteral stent tube comprises a hollow tube body arranged in the ureter of a patient, a first inserting part arranged in the bladder of the patient and and a second inserting part arranged in the pelvis of the patient, wherein the first inserting part and the second inserting part are respectively arranged at two ends of the hollow tube body and are connected with the hollow tube body through a plurality of connecting pieces; the plurality of connecting pieces are arranged in acircumferential direction of the hollow pipe body at intervals; a urine inlet is arranged between every two adjacent connecting pieces in a spaced mode; an elastic column used for controlling the urine inlet to be opened and closed is arranged at each urine inlet; a sliding block capable of sliding in a length direction of the connecting pieces is arranged among the plurality of connecting pieces;one ends of the elastic columns are connected with and arranged on the hollow tube body; the other ends of the elastic columns are connected with and arranged on the sliding block; and the ureteral stent tube also comprises a control component used for controlling the sliding block to slide. According to a scheme of the invention, the ureteral stent tube has the advantages of reducing stimulationand damage to bladder mucosa, reducing hematuresis and improving comfort of a patient.

The invention provides a pharmaceutical composition for treating nephrolithiasis, which can effectively treat nephrolithiasis, shorten the treatment time of nephrolithiasis, inhibit inflammation, reduce the recurrence rate of calculi, and can obviously improve hydrops in renal pelvis and ureter, Alleviating the pain of nephrolithiasis and lumbago, the clinical curative effect is sure, the clinical medication is safe, and has excellent application prospect.

The invention discloses a method for collecting and verifying the microecology of renal pelvis urine microecology. Further verification and comparison of the differences between the microecological structure of the renal pelvis and the microecological structure of the bladder can accurately determine whether the microecology of the renal pelvis is polluted, which is of substantial significance for the subsequent analysis of the microecology of the renal pelvis and the analysis of the relationship between the microecology of the renal pelvis and kidney diseases.

The invention discloses a device for calculus irrigation and decompression in ureteroscope lithotripsy. The device comprises a ureteral sheath for constructing an operation channel and a bladder sheath for constructing a decompression channel, wherein a first gap is left between the ureteral sheath and the ureteroscope; and a second gap is left between the ureteral sheath and the ureteroscope. A bladder sheath is arranged outside the ureteral sheath, and the bladder sheath and the ureteral sheath can be slidably and fixedly connected, At that end of the bladder sheath extend into the bladder,One end of the conical tube with a larger outer diameter is connected with the bladder sheath, the inner diameter of the smaller end of the conical tube is adapted to the outer diameter of the ureteral sheath, a through hole penetrating through the wall of the conical tube is arranged on the outer side wall, and a second gap is left between the inner side wall of the bladder sheath and the outer side wall of the ureteral sheath for returning liquid. The device can facilitate the access of the ureteroscope by establishing a fixed operation channel, facilitate the flushing out of the crushed calculus, smooth the fluid return and the decompression of the renal pelvis and bladder.