The invention discloses a ureter guide sheath, and belongs to the technical field of medical instruments. The ureter guide sheath comprises a sheath pipe base, a sheath pipe is connected with one endof the sheath pipe base, the other end of the sheath pipe base is embedded into a center hole of an expansion pipe connector through an expansion pipe, a clamping hook is arranged on the expansion pipe connector, a clamping table matched with the clamping hook is arranged at one end, close to the expansion pipe connector, of the sheath pipe base, a hand shank is arranged at one end, far away fromthe expansion pipe connector, of the sheath pipe base through a sleeve in a sleeving manner, the hand shank is perpendicular to the sleeve and comprises a pipeline and a handle, the handle is fixedlyarranged at the bottom of the pipeline, the sheath pipe base is communicated with the pipeline through a second through hole, a boss is arranged between the clamping table on the sheath pipe base andthe second through hole, the boss and the second through hole are positioned on the same side, a semicircular open groove matched with the boss is formed in the upper edge of the sleeve, and the handshank can rotate clockwise by 180 degrees along a center axis of the sheath pipe base under the limiting actions of the boss and the semicircular open groove. The ureter guide sheath is conveniently operated by a doctor, and smooth implementation of ureteroscope surgery can be ensured.