The invention relates to gluten-free germinated brown rice and soybean bread and a making method thereof and belongs to the technical field of food and making methods thereof. The gluten-free germinated brown rice and soybean bread is prepared from, by weight, 80-90 parts of germinated brown rice powder, 10-20 parts of defatted soybean powder, 1-2 parts of hydroxypropyl methyl cellulose, 0.2-0.3 part of xanthan gum, 0.5-1.5 parts of transglutaminase, 2-3 parts of yeast, 5-10 parts of cane sugar, 1-3 parts of salt, 4-6 parts of edible vegetable oil and a proper amount of water. According to the gluten-free germinated brown rice and soybean bread and the making method thereof, the germinated brown rice powder and the defatted soybean powder are used as the main raw materials, no gluten is contained, two types of water-soluble edible gum, namely hydroxypropyl methyl cellulose and xanthan gum, are compounded, the catalytic effect of transglutaminase is added, the nutritious health-care function, the protein biological titer and quality of the bread are improved, and the bread can serve as staple food bread of a patient suffering from gluten-induced enteropathy (celiac sprue) and also can serve as healthy health-maintenance food of ordinary people.