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48 results about "Fovea centralis" patented technology

The fovea centralis is a small, central pit composed of closely packed cones in the eye. It is located in the center of the macula lutea of the retina. The fovea is responsible for sharp central vision (also called foveal vision), which is necessary in humans for activities for which visual detail is of primary importance, such as reading and driving. The fovea is surrounded by the parafovea belt and the perifovea outer region.

Pattern analysis of retinal maps for the diagnosis of optic nerve diseases by optical coherence tomography

Methods for analyzing retinal tomography maps to detect patterns of optic nerve diseases such as glaucoma, optic neuritis, anterior ischemic optic neuropathy are disclosed in this invention. The areas of mapping include the macula centered on the fovea, and the region centered on the optic nerve head. The retinal layers that are analyzed include the nerve fiber, ganglion cell, inner plexiform and inner nuclear layers and their combinations. The overall retinal thickness can also be analyzed. Pattern analysis are applied to the maps to create single parameter for diagnosis and progression analysis of glaucoma and optic neuropathy.
Owner:USC STEVENS UNIV OF SOUTHERN CALIFORNIA

Ophthalmic Lens Element for Myopia Correction

An ophthalmic lens element (100) for correcting myopia in a wearer's eye is disclosed. The lens element (100) includes a central zone (102) and a peripheral zone (104). The central zone (102) provides a first optical correction for substantially correcting myopia associated with the foveal region of the wearer's eye. The peripheral zone (104) surrounds the central zone (102) and provides a second optical correction for substantially correcting myopia or hyperopia associated with a peripheral region of the retina of the wearer's eye. A system and method for dispensing or designing an ophthalmic lens element for correcting myopia in a wearer's eye is also disclosed.
Owner:CARL ZEISS VISION AUSTRALIA HO +1

Retina fovea centralis detection method based on multi-feature model

The invention discloses a retina fovea centralis detection method based on a multi-feature model. The retina fovea centralis detection method comprises the following steps: 1) carrying out global prior feature extraction; 2) carrying out local prior feature extraction; 3) carrying out depth feature extraction; and 4) establishing a multi-feature-fusion fovea centralis detection model. Through global, local and depth feature information extraction of fovea centralis and effective fusion, accurate detection of the retina fovea centralis is finished. The method can effectively overcome the influence of fundus illumination noise, fundus lesions and abnormal blood vessel distribution on fovea centralis automatic detection, thereby improving fovea centralis detection precision and robustness, and providing more robust identity characteristic information for identity identification based on retinal images.
Owner:HARBIN INST OF TECH

Mutual acting staring vision-training system and method

An interactive gazing vision training system comprises software loaded in a computer, gaming handle connected to the computer. Computer generated signal can be projected on projection screen after being input in projector. The total system can project 4-8 wickets controlled independently by gaming handle on projection screen. The gaming handle has buttons corresponding to each corresponding sighting direction. Sighting target in the wicket can wane continually under the control of the computer. Trainee sit at a place 2-5 m away from the projection screen, light ray emitted by any point on the projection screen enter the eyeball of the trainee via optical lens, and the hearth in the eye is located at a place 0.5-2mm in front of fovea centralis of niacula lutea retinae. The inventive interactive gazing vision training system integrates multiple modern theories for preventing and treating myopia, adopts the advantages of games, utilizes 3Dexaggeration technology, increases entertaining quality, and becomes an easily persistent eyes protection method.
Owner:北京眼吧科技有限公司

Short-Coherence Interferometeric Measurement of Length on the Eye

Two problems arise when measuring length at the eye by short-coherence interferometry. First, the measurement focus and coherence window usually do not coincide. Second, the scanning process along the eye axis is time-consuming. Both result in poor signal quality and inaccurate measurements. The present application is directed to a short-coherence interferometer in which a right-angle mirror and focusing optics jointly carry out a periodic back-and-forth movement in such a way that the measurement beam focus which is generated by the focusing optics and imaged on the eye by relay optics is moved synchronously with the coherence window from the cornea along the optic axis of the eye to the fovea centralis. Further, different path lengths are generated in the measurement beam path and reference beam path by means of a plurality of reflectors, so that the scanning process is limited to distances which are smaller than the optical length of the eye. The present invention is advantageously implemented using on a fiber-optic interferometer. According to the invention, the reference interferometer arm and measurement interferometer arm are combined with the arms of a fiber-optic interferometer.
Owner:CARL ZEISS MEDITEC AG

Adaptive parameters in image regions based on eye tracking information

A display system divides a screen into regions and applies a different set of rendering / encoding parameters to each region. The system applies a first set of parameters to a first region that is beingviewed by a fovea of an eye of a user. The system may also apply a second set of parameters to a second region that is being viewed by a parafovea of the eye, and apply a third set of parameters to athird region that is being viewed by the area of the eye outside of the parafovea. The first set of parameters is selected to yield relatively high image quality, while the second set of parameters are yield intermediate quality, and the third set of parameters yield lower quality. As a result, the second region and the third region can be rendered, encoded, and transmitted with less computing power and less bandwidth.
Owner:CTRL LABS CORP

Prism prescription value acquisition system, acquisition method, acquisition apparatus and program for correcting fixation disparity

ActiveUS20150351625A1Simple and quick and accurate mannerEye diagnosticsAcquisition apparatusPrism
A prism prescription value acquisition system that includes a calculation part for numerically transforming a fixation disparity amount (unit: angle), which indicates a degree at which the visual axis is shifted from the central fovea of the retina when a subject conducts visual fixation of a target, into a prism prescription value by multiplying the fixation disparity amount by a coefficient when the fixation disparity amount is within ±4 minutes. Herein, the prism prescription value is calculated according to the following equation: APver=kver*FDver, APhor=khor*FDhor providing that each of coefficients khor and kver satisfies the following conditions: 0.3≦kver≦0.7, 1.4≦khor≦2.0.
Owner:HOYA CORP

System and process for neuroprotective therapy for glaucoma

Provided is neuroprotective therapy for glaucoma which includes generating a micropulsed laser light beam having parameters and characteristics, including pulse length, power, and duty cycle, selectedto create a therapeutic effect with no visible laser lesions or tissue damage to the retina. The laser light beam is applied to retinal and / or foveal tissue of an eye having glaucoma or a risk of glaucoma to create a therapeutic effect to the retinal and / or foveal tissue exposed to the laser light beam without destroying or permanently damaging the retinal and / or foveal tissue and improve function or condition of an optic nerve and / or retinal ganglion cells of the eye.
Owner:OJAI RETINAL TECH

Visual target tracking method of bionic retina

The invention discloses a visual target tracking method of a bionic retina, and belongs to the field of photoelectric target tracking. According to the invention, the variable resolution characteristic of bionic retina imaging is mainly utilized, and the field of view is mapped to the logarithm polar coordinates for target tracking. Firstly, logarithm polar coordinate mapping imaging of a bionic retina is utilized, a target tracking algorithm is improved through the staring effect of a fovea centralis, the information compression effect of an edge and real-time parameters, redundant data are compressed, detail information of an interested target is enhanced, and the information acquisition efficiency in a view field range is improved. And meanwhile, target information in a scene is accurately grasped by utilizing singular points and imaging threshold judgment, and the reliability of target screening is improved. And finally, real-time target tracking is realized by comparing an eccentricity judgment algorithm with higher speed with the motion control module. Compared with a traditional method, under the condition of a large field of view and high resolution, real-time target tracking is achieved on the basis of a bionic retina vision mechanism, efficiency is higher, and precision is higher.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY

Short-coherence interferometric measurement of length on the eye

Two problems arise when measuring length at the eye by short-coherence interferometry. First, the measurement focus and coherence window usually do not coincide. Second, the scanning process along the eye axis is time-consumin g. Both result in poor signal quality and inaccurate measurements. The present application is directed to a short-coherence interferometer in which a right-angle mirror and focusing optics jointly carry out a periodic back-and-forth movement in such a way that the measurement beam focus which is generated by the focusing optics and imaged on the eye by relay optics is moved synchronously with the coherence window from the cornea along the optic axis of the eye to the fovea centralis. Further, different path lengths are generated in the measurement beam path and reference beam path by means of a plurality of reflectors, so that the scanning process is limited to distances which are smaller than the optical length of the eye. The present invention is advantageously implemented using on a fiber-optic interferometer. According to the invention, the reference interferometer arm and measurement interferometer arm are combined with the arms of a fiber-optic interferometer.
Owner:CARL ZEISS MEDITEC AG

Method and device for determining macular fovea centralis position

The invention discloses a method and a device for determining a macular fovea centralis position, and relates to the technical field of artificial intelligence such as smart medical treatment and computer vision. According to the specific implementation scheme, the method comprises the steps of determining a feature region from a to-be-processed fundus image, wherein the feature region comprises an optic disc region and a blood vessel region in the fundus image; adopting a pre-trained position prediction model to estimate the relative displacement of each feature point in the feature region relative to the macular fovea central fovea prediction position; based on the position information of each feature point and the relative displacement of the feature point, determining a mapping point corresponding to the feature point in the fundus image to obtain a mapping point set; and determining the position of the macular fovea based on the position information of each mapping point in the mapping point set. The positioning accuracy of macular fovea centralis is improved, and the influence of lesion shielding on the positioning accuracy can be avoided.
Owner:北京康夫子健康技术有限公司

SD-OCT image macular fovea centralis center positioning method

The invention discloses an SD-OCT image macular fovea centralis center positioning method. The method comprises the following steps: segmenting an inner boundary film layer and a Bloom film layer of an SD-OCT image; extracting each column of pixels between the inner boundary film layer and the Bloom film layer as features; training a random forest classifier to segment a fovea centralis non-vascular region, and calculating the geometric center position of the fovea centralis non-vascular region as the rough center position P1 of the macular fovea centralis; a retina thickness image is generated within a certain range with P1 as the center; judging whether the retina in the area is sunken or not, and if yes, taking the position at the minimum thickness value as a new foveal fovea central position P2; if not, the P2 is still the position of the P1; and searching a central concave high-reflection region around the position P2, if the high-reflection region exists, taking the central position of the high-reflection region as a final central concave central position P3, and otherwise, taking the P3 as the position P2. Compared with the conventional method for positioning only accordingto the thickness change of the retina, the robustness and the precision of the method are greatly improved.
Owner:NANJING UNIV OF SCI & TECH +2

Systems and methods for head-mounted display adapted to human visual mechanism

Systems and methods are provided for rendering of a dual eye-specific display. The system tracks the user's eye movements and / or positions, in some implementations, based on electroencephalography (EEG) of the user, to correctly label the central (foveal) and peripheral (extra-foveal) areas of the display. Foveal data is fully rendered while extra-foveal data is reduced in resolution and, in someimplementations, shared between the two displays.
Owner:MOVIDIUS LTD

System and process for retina phototherapy

A process for performing retinal phototherapy or photostimulation includes generating a laser light that creates a therapeutic effect to retinal and / or foveal tissues exposed to the laser light without destroying or permanently damaging the retinal or foveal tissue. The laser light is applied to a first treatment area of the retina. After a predetermined interval of time, within a single treatmentsession, the laser light is reapplied to the first treatment area of the retina. During the interval of time between the laser light applications to the first treatment area, the laser light is applied to one or more additional areas of the retina that is spaced apart from the first treatment area and one another. The laser light is repeatedly applied to each of the areas to be treated until a predetermined number of laser light applications to each area to be treated has been achieved.
Owner:OJAI RETINAL TECH

Eye tracking fixation monitoring systems and methods

Systems and methods for tracking eye movement during a diagnostic procedure include a retina imaging system configured to capture a first plurality of images of an eye and detect a presence of a fovea, an eye tracker configured to capture a second plurality of images of the eye and track a position and orientation of the eye; and a control processor configured to synchronize the first and second plurality of images, determine a time at which the fovea is detected in the first plurality of images, and determine one or more images from the second plurality of images to be classified as representative of fixation. The classified images are analyzed to determine eye fixation status during the diagnostic procedure based on eye tracking data.
Owner:ALCON INC

Fundus optic disc and fovea centralis real-time detection device and method based on deep learning

The invention belongs to the technical field of medical image processing, and aims to realize real-time fundus optic disc and fovea centralis detection based on deep learning and improve the detectionprecision and speed of the optic disc and the fovea centralis. Therefore, according to the technical scheme, the fundus optic disc and fovea centralis real-time detection device and method based on deep learning are adopted, a fundus optic disc and fovea centralis detection network based on a single-stage multi-frame detection SSD algorithm is constructed, parameters of a network model are optimized through multiple times of iterative learning, and the detection precision of the network model is improved. And real-time positioning of the optic disc and the fovea centralis center in a large number of fundus images is realized. The method is mainly applied to medical image processing occasions.
Owner:TIANJIN UNIV

Method for realizing flexible central fovea imaging based on rotary biprism imaging system

ActiveCN113759543AReduce in quantityGuaranteed Foveal Imaging PerformanceImage enhancementPrismsImage resolutionEngineering
The invention relates to a method for realizing flexible central fovea imaging based on a rotary biprism imaging system. The method comprises the steps of S1, constructing a rotary biprism imaging system; S2, constructing a fitness function, and defining a definition and calculation method of a fitness value; S3, determining a region of interest and the number of sub-images, and solving a prism rotation angle by using a particle swarm optimization algorithm; S4, sequentially adjusting the rotation angles of the prisms according to the result of the particle swarm optimization algorithm, and collecting images; S5, carrying out distortion correction on the collected images; S6, splicing the distorted and corrected images to obtain a large field of view; and S7, performing super-resolution reconstruction on the region of interest to further improve the resolution of the central fovea region. According to the invention, central fovea imaging with flexible adjustment of the region of interest can be realized, and acquisition of an overall large field of view is considered. Besides, central fovea imaging can be realized only by using the single rotary biprism imaging system, so that the complexity of equipment is greatly reduced, and the method has excellent practical value.
Owner:FUZHOU UNIV

Methods of expressing a polynucleotide of interest in the cone photoreceptors of a subject comprising the subretinal delivery of a therapeutically effective amount of a recombinant aav9-derived vector

Several new vector-promoter combinations to overcome the limitations associated with AAV-mediated cone transduction in the fovea are provided. The delivery modality relies on a cone-specific promoter and result in high-level transgene expression compatible with optogenetic vision restoration. Methods of expressing a polynucleotide of interest in the cone photoreceptors of a subject comprising subretinal delivery of a therapeutically effective amount of a recombinant AAV9-derived vector comprising a VP1 capsid protein as set forth in SEQ ID NO: 11 and the polynucleotide of interest under the control of the pR1.7 promoter as set forth in SEQ ID NO: 12 are also provided.
Owner:INST NAT DE LA SANTE & DE LA RECHERCHE MEDICALE (INSERM) +1

Methods of expressing a polynucleotide of interest in the cone photoreceptors of a subject comprising the subretinal delivery of a therapeutically effective amount of a recombinant aav9-derived vector

Intraocular injection of adeno-associated viral (AAV) vectors has been an evident route for delivering gene drugs into the retina. Currently, the vectors need to be injected into the subretinal spacein order to provide gene delivery to cones. In this approach, gene delivery is limited to cells that contact the local "bleb" of injected fluid. Furthermore, retinal detachment that occurs during subretinal injections is a concern in eyes with retinal degeneration. Here, the inventors establish several new vector-promoter combinations to overcome the limitations associated with AAV-mediated cone transduction in the fovea with supporting studies in mouse models, human induced pluripotent stem cell-derived organoids, post-mortem human retinal explants and living macaques. They show that an AAV9variant provides efficient foveal cone transduction when injected into the subretinal space several millimeters away from the fovea, without detaching this delicate region. The delivery modality relies on a cone-specific promoter and result in high-level transgene expression compatible with optogenetic vision restoration. Accordingly, the present invention relates to method of expressing a polynucleotide of interest in the cone photoreceptors of a subject comprising subretinal delivery of a therapeutically effective amount of a recombinant AAV9-derived vector comprising a VP1 capsid protein asset forth in SEQ ID NO: 11 and the polynucleotide of interest under the control of the pR1.7 promoter as set forth in SEQ ID NO: 12.
Owner:ASSISTANCE PUBLIQUE HOPITAUX DE PARIS +1

Determination of a change in the refraction error of an eye

The present invention relates to a method (210), a device (110) and a computer program for determining a refractive error of an eye (112) of a user (114). The method (210) for determining the refractive error of the eye (112) of the user (114), wherein the eye (112) of the user (114) has a choroid (124), comprises the following steps: a) determining at least one value for a layer thickness (122) of the choroid (124) of the eye (112) of the user (114) over at least one region (150) of the choroid (124); and b) determining a value (216) for the change in the refractive error of the eye (112) exclusively from at least two values for the layer thickness (122) of the choroid (124), each of which have been determined at different times for the at least one region (150) of the choroid (124), wherein the at least one region (150) is selected from a nasal perifoveal region (168) or a nasal parafoveal region (166).
Owner:CARL ZEISS VISION INT GMBH

Bionic visual image target recognition method fusing dot-line memory information

ActiveCN110598534APrecise and detailed visual contentImprove recognition rateCharacter and pattern recognitionSensory cellViewpoints
The invention discloses a bionic visual image target recognition method fusing dot-line memory information, and the method comprises the steps of constructing a grid cell set based on visual drive, constructing a distance cell model, and calculating a displacement vector between the positions coded by a grid cell group vector; calculating the response of all sensory neurons to each central concavepixel k through a Gaussian kernel, wherein the response is used for target recognition; calculating the fovea centralis of the current target image by using Gaussian nuclear sensory cells, taking thefeature tag unit with the strongest response as the next jump point, and accumulating the corresponding stimulated identity cells; selecting a next-hop viewpoint, and updating a foveal displacement vector through a distance cell model; and circularly repeating the calculation of the current position during the target identification process, selecting the next-hop viewpoint, and carrying out the vector calculation until the accumulation of a certain stimulated identity cell reaches a threshold value 0.9, and considering the stimulated identity as the finally identified target. The method provided by the invention has a relatively higher recognition rate for the position change, zooming and shielded images.
Owner:CENT SOUTH UNIV
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