140 results about "Eye corneas" patented technology

Head-mounted displays (100) are disclosed which include a frame (107), an image display system (110) supported by the frame (107), and a Fresnel lens system (115) supported by the frame (107). The HMD (100) can employ a reflective optical surface, e.g., a free-space, ultra-wide angle, reflective optical surface (a FS / UWA / RO surface) (120), supported by the frame (107), with the Fresnel lens system (115) being located between the image display system (110) and the reflective optical surface (120). The Fresnel lens system (115) can include at least one curved Fresnel lens element (820). Fresnel lens elements (30) for use in HMDs are also disclosed which have facets (31) separated by edges (32) which lie along radial lines (33) which during use of the HMD pass through a center of rotation (34) of a nominal user's eye (35) or through the center of the eye's lens (36) or are normal to the surface of the eye's cornea.

The invention relates to a device for cutting the cornea of an eye to correct the refractive power thereof, having a frame that comprises a fixation ring, which may be drawn onto the eye, as well as a receptacle, which may be coaxially displaced relative to the fixation ring and which serves to accommodate an applanator for deforming the cornea within the fixation ring, and a holding device, which is guided on the frame in a plane that is perpendicular to the axis with regard to the fixation ring and which serves to hold a blade, which passes through the frame via a peripheral recess and which is mounted in front of the applanator, being radially displaceable relative to the fixation ring as well as movable around an axis perpendicular to the guiding plane, for the purpose of cutting a pocket through a merely tunnel-like entry into the corneal tissue. In order to obtain advantageous cutting conditions, it is suggested to have the blade pass through the frame recess with clearance, and to have the holding device support a vibrator for setting the blade in oscillatory motion in the cutting plane.

In accordance with some embodiments, a method of eye examination includes acquiring OCT data with a scan pattern centered on an eye cornea that includes n radial scans repeated r times, c circular scans repeated r times, and n* raster scans where the scan pattern is repeated m times, where each scan includes a A-scans, and where n is an integer that is 0 or greater, r is an integer that is 1 or greater, c is an integer that is 0 or greater, n* is an integer that is 0 or greater, m is an integer that is 1 or greater, and a is an integer greater than 1, the values of n, r, c, n*, and m being chosen to provide OCT data for a target measurement, and processing the OCT data to obtain the target measurement.

The invention is related to a method for making a silicone hydrogel contact lens having a nano-textured surface which mimics the surface texture of cornea of human eye. A method of the invention comprises creating a prime coating having nano-textures through controlled imbibition and / or depositions of a reactive polymeric coating material and fixing the nano-textures by crosslinking a hydrophilic polymeric material onto the prime coating to form a crosslinked polymeric coating that perserves the nano-textures of the prime coating and provides a nano-textured surface to the contact lens.

A method for generating control data for an eye-surgical treatment device, which separates tissue layers in the eye cornea by application of a laser device, wherein a contact glass having a contact surface deforms the cornea to conform to the shape of the contact surface during the operation of the laser device. The contact surface is first placed on a cornea apex at a contact surface apex and is then pressed against the same for deforming the cornea. The method includes: generating the control data of the laser device such that the data specifies coordinates of target points located in the cornea for the laser device, and upon generation of the target point coordinates the deformation of the cornea which is present during the operation of the laser device as a result of the contact glass is taken into consideration. The invention provides that the several steps are carried out in consideration of the deformation in order to determine a displacement of a point P in the undeformed cornea caused by the deformation.

The invention discloses an eyeball-tracking device, comprising two eyeball-tracking modules used for tracking the sight of a user; each of the two eyeball-tracking modules is disposed to correspond with one eye; each of the two eyeball-tracking modules comprises a light source component and at least one image sensor component; the light source components face to the direction of eyes of the user and can form at least one corneal reflective spot on eye corneas of the user; the at least one image sensor component is used for continuously capturing images of the eyes of the user; and the image sensor component in each of the eyeball-tracking modules can only receive light emitted by the light source component in the corresponding eyeball-tracking module. The invention also discloses head-mounted virtual reality equipment and head-mounted augmented reality equipment by use of the eyeball-tracking device. According to the eyeball-tracking device, the head-mounted virtual reality equipment and the head-mounted augmented reality equipment by use of the eyeball-tracking device, the problem that the light source components interfere with each other when calibration or in use can be effectively avoided.

An automated eye corneal striae detection system for use with a refractive laser system includes a cornea illuminator, a video camera interface, a computer, and a video display for showing possible eye corneal striae to the surgeon. The computer includes an interface to control the corneal illuminator, a video frame grabber which extracts images of the eye cornea from the video camera, and is programmed to detect and recognize eye corneal striae. The striae detection algorithm finds possible cornea striae, determines their location, or position, on the cornea and analyzes their shape. After all possible eye corneal striae are detected and analyzed, they are displayed for the surgeon on an external video display. The surgeon can then make a determination as to whether the corneal LASIK flap should be refloated, adjusted or smoothed again.

An automated eye corneal striae detection system for use with a refractive laser system includes a cornea illuminator, a video camera interface, a computer, and a video display for showing possible eye corneal striae to the surgeon. The computer includes an interface to control the corneal illuminator, a video frame grabber which extracts images of the eye cornea from the video camera, and is programmed to detect and recognize eye corneal striae. The striae detection algorithm finds possible cornea striae, determines their location, or position, on the cornea and analyzes their shape. After all possible eye corneal striae are detected and analyzed, they are displayed for the surgeon on an external video display. The surgeon can then make a determination as to whether the corneal LASIK flap should be refloated, adjusted or smoothed again.

The gonioscope of the invention comprises a hollow tapered body with mirror surfaces formed on the inner side of the gonioscope or on the inserts placed into the recesses on the inner surface of the gonioscope. Several reflecting surfaces arranged at the same or different angles can be used. The device can be made disposable and molded with reflecting surface coatings applied onto the inner flats. According to one of the embodiments, the gonioscope can be used in combination with a meniscus lens that can applied onto the eye cornea and used as a support for sliding the front end of the gonioscope over the lens surface for orientation thereof at different angles to the optical axis of the eye.

The invention discloses a tacrolimus eye ointment for cornea transplantation and a preparation method thereof, belongs to the field of pharmaceutical preparation and particularly relates to a tacrolimus eye precursor vesicle capsule for cornea transplantation and a preparation method thereof. The precursor vesicle capsule comprises the following raw materials in percentage by weight: 0.04-0.8% of tacrolimus, 4.0-41.0% of surfactant, 1.6-8.0% of cholesterol, 4.0-41.0% of lecithin, 1.2-30.% of alcohol, and the balance of water or 0,1% of glycerol aqueous solution or phosphate buffer with PH of 7.4, wherein the surfactant is one of span, tween, polyoxyethylene ether castor oil and poloxamer, and the alcohol is one of ethanol, isopropanol, butanol and propanol. The tacrolimus precursor vesicle capsule has limited moisture, and the storage stability of the preparation can be improved; the product organically combines the advantages of the precursor vesicle capsule, the characteristics of an eye dosing system and the indication disease of the tacrolimus drugs, so as to achieve the advantages of improving the curative effect, reducing the side effect, and bringing convenience in administration; and the preparation technique is simple and convenient and is suitable for industrial production.

In accordance with some embodiments, a method of eye examination includes acquiring OCT data with a scan pattern centered on an eye cornea that includes n radial scans repeated r times, c circular scans repeated r times, and n* raster scans where the scan pattern is repeated m times, where each scan includes a A-scans, and where n is an integer that is 0 or greater, r is an integer that is 1 or greater, c is an integer that is 0 or greater, n* is an integer that is 0 or greater, m is an integer that is 1 or greater, and a is an integer greater than 1, the values of n, r, c, n*, and m being chosen to provide OCT data for a target measurement, and processing the OCT data to obtain the target measurement.

The invention discloses a method for locating an eyeball cornea. The method comprises the steps of utilizing a CV mode identification solution in opencv (open source computer vision library) for training to obtain an eye classifier and generating a relevant XML (extensible makeup language) file; setting a rectangular eye region captured by a camera as a region of interest (ROI); carrying out smoothing to an ROI image, and carrying out edge detection; and carrying out Hough circular transformation in an obtained edge image by utilizing the characteristic that an eye cornea has remarkable circular shape, and identifying a circular sequence in the region, namely, determining that the sequence is the region where the cornea is located and the position where the center of circle is located is the pupil. An accurate and reliable position of the eye cornea can be obtained by adopting the process of the invention. The detection method has the advantages of wide application scope, high identification precision, simple detection equipment and the like.

An agent for dehydrating corneas, in particular eye corneas for organ culture, contains the culture medium and as dehydrating substance hydroxyethylstarch with a mean molecular weight Mw from 070,000 to 200,000, an MS substitution degree from 0.15 to 0.5, a DS substitution degree from 0.15 to 0.5 and a C2-C6 substitution ratio at the anhydroglucose units < / =8. The dehydrating substance is preferably hydroxyethylstarch with a mean molecular weight Mw 130,000+ / -20,000, an MS substitution degree from 0.38 to 0.45, a DS substitution degree from 0.32 to 0.40 and a C2-C6 substitution ratio at the anhydroglucose units from 8 to 20. The hydroxyethylstarch is used in a concentration from 1 to 20 (weight / vol.) %, preferably from 2 to 15 (weight / vol.) %, and in particular of 7.5% (weight / vol.). Also disclosed is the use of this hydroxyethylstarch as a dehydrating substance for the organ culture of corneas, in particular eye corneas, and the use of this hydroxyethylstarch for preparing a dehydrating agent for corneas, in particular eye corneas for organ culture.

The invention provides an electric cutting device for rapidly cutting animal corneas. The electric cutting device comprises a front eyeball fixing box arranged on a bottom fixing frame, and a lifting motor, wherein the lifting motor can be used for driving a back eyeball fixing box to move; the back eyeball fixing box is connected with a movable fixing frame; a sclerotome motor arranged on the movable fixing frame is used for driving a rotary sclerotome to cut an animal eyeball to form a circular sclerotome edge; a cutter barrel motor is used for driving a cornea cutting tool to move downwards along a sliding cavity, and is used for cutting a lower cornea by cooperating with a fixed cutter barrel on the outer ring of a cornea contact grid; when a bracket motor arranged on the bottom fixing frame is used for driving a movable suction bracket to move downwards, negative pressure is generated in a movable sealing ring to adsorb the cornea onto the air-permeable cornea contact grid; after the movable suction bracket is taken out and the cornea on the cornea contact grid is taken down, batch cutting can be performed repeatedly. The electric cutting device has the beneficial effects that the cutting device can be driven by the motor to rapidly cutting animal corneas, and standard corneas with regular edges can be obtained in batch for use in batch data scientific research and application.

The invention provides a laser cornea cutting device for an experimental animal. The laser cornea cutting device for the experimental animal comprises a lower bracket mounted on a bottom plate of a sealing cabin and an upper compressing cover, and eyeballs of the experimental animal can be compressed between the lower bracket and the upper compressing cover. Eyeball cornea penetrates through a circular hole in the middle of the upper compressing cover to be exposed out, and a hollow rotation tube driven by a driving motor penetrates through the top of the sealing cabin and can rotate freely. A laser generator is fixed on a movable link rod and can be adjusted up and down and front and back, so that it is guaranteed that a focus point of a laser beam can be placed on the outer circle of the cornea. The uppermost portion of the hollow rotation tube is connected to the inside of an atomization cavity, the lower edge of the hollow rotation tube is connected with a mist diffusion opening, atomized normal saline can be transmitted, the laser beam emitted by the laser generator which rotates at a constant speed makes circular motion on the focus point along the outer edge of the cornea, neat and clean cutting is achieved, and the standard cornea with good consistency is obtained. The laser cornea cutting device for the experimental animal has the advantages that blade cutting is avoided, and the problem for conducting mass standard animal cornea cutting work conveniently, rapidly, automatically, safely and accurately is solved.

This invention relates to the new applications of the Rose liquid in the preparation of the eye drops. The Rose liquid can be prepared by distillation from the mixture of rose and water with ratio of 1:1-10 by weight. Distilled water is better controlled by 2-20% of the total lolume of water per hr. distilling time is controlled by 30-60min. The eye drops by using the distilled rose water (as the main raw material) can effectively remit the eye tiredness, dryness, itching with fine curative effect to the anaphylaxis or inflammation or infection of the eye cornea and conjunctiva but with very light irritation. The eye drops also has the character of high effectiveness, light toxin, less untoward effect. It has broad application foreground.

The present invention discloses a device for sight tracking free of scaling. The objective of the invention is to realize tracking of a device user's watching position. The device comprises a plurality of sight tracking modules, each sight tracking module has different space coordinates in a target area, each sight tracking module comprises at least one light source and is configured to form a cornea reflective spot (a first Purkinje image) on the user's cornea, and each sight tracking module also comprises at least one image obtaining unit configured to capture user's cornea reflective spot image and pupil image. The device also comprises a data processing module configured to determine the user's sight watching position or position area according to the cornea reflective spot image and the pupil image and store the data of the user watching the space coordinates. The present invention further discloses a method applied to the sight tracking device. The device and method for sight tracking free of scaling are free of scaling or calibration, can conveniently track the device user's sight and determine the user's watching position and watching area.

In accordance with some embodiments, a method of eye examination includes acquiring OCT data with a scan pattern centered on an eye cornea that includes n radial scans repeated r times, c circular scans repeated r times, and n* raster scans where the scan pattern is repeated m times, where each scan includes a A-scans, and where n is an integer that is 0 or greater, r is an integer that is 1 or greater, c is an integer that is 0 or greater, n* is an integer that is 0 or greater, m is an integer that is 1 or greater, and a is an integer greater than 1, the values of n, r, c, n*, and m being chosen to provide OCT data for a target measurement, and processing the OCT data to obtain the target measurement.

The invention relates to an ophthalmic in-situ jelly of chiral anti-glaucoma medicine levofloxacin tropane. The ophthalmic jellies concretely comprises 0.03 percent to 0.3 percent of levofloxacin tropane, 10 percent to 20 percent of hydrophilic polymer material, 0 percent to 20 percent of humectant, 0.1 percent to 10 percent of permeation pressure regulator, 0.01 percent to 0.3 percent of antiseptic / bacteriostat, pH value regulator and water. In a preparation method, the materials are weighted according to the percentage; the levofloxacin tropane is solved in injection water, the hydrophilic polymer material is added under the stirring state, and the solution is stood over a night; the adjuvant such as the humectant and the like is added, and the pH value is adjusted as 4 to 9; the solution is filtered, the injection water is added to the total quantity, and the ophthalmic in-situ jelly is obtained. The ophthalmic in-situ jelly has the advantages of uniform and smooth quality, proper viscosity, convenient use, exact dosage, and long-term uniform distribution on the surface of eye cornea; besides, the jelly causes no hypersusceptibility and irritation, no blurred vision, can effectively prolong the acting time of the medicine on the eye cornea, and has wide application prospect.

The invention relates to a corneal shaping lens. The corneal shaping lens comprises an inner surface facing the human cornea during wearing and an outer surface opposite to the inner surface, whereinthe inner surface comprises a base curve area located in the center, the base curve area is used for pressing the front surface of the cornea and shaping the front surface of the cornea to be consistent with the base curve area and comprises two or more areas, and the at least two of the areas have different curvature radii.

The invention provides a fast animal cornea cutting device which comprises a front eyeball fixing box and a rear eyeball fixing box, wherein the front eyeball fixing box and the rear eyeball fixing box are tightly buckled together to fix an animal eyeball; eyeball fixing needles are arranged on the two boxes; a rotary sclera knife is arranged on the rear eyeball fixing box to cut a sclera open and enable a cornea cutting knife to penetrate through the cut sclera, move downwards along a sliding cavity running through the middle parts of the boxes, and interact with a fixed knife cylinder on the outer ring of a cornea contact grid to cut down the cornea; when a movable suction bracket is drawn outwards, a displaceable seal ring is stretched to expand the volume of the interior of a negative-pressure fixed cavity so as to generate negative pressure and enable the cornea to be attached to the ventilated cornea contact grid and to be taken out; after the movable suction bracket is drawn out, the shape of the displaceable seal ring is recovered and the negative pressure disappears, the cornea on the cornea contact grid can be taken down easily, and the subsequent scientific research and application can be performed. The invention has the benefit that the fast animal cornea cutting device can perform manual operation of cutting an animal eyeball conveniently and fast so as to obtain a standardized cornea with a neat edge for scientific research and application.

The invention belongs to the technical field of ophthalmic lenses, and particularly relates to an intraocular lens resistant to eccentricity and inclination clinically. The intraocular lens resistantto eccentricity and inclination clinically is a high-order aspheric intraocular lens with weak negative spherical aberration, and the intraocular lens is placed in a posterior chamber of the human eyeto replace a turbid natural lens. The intraocular lens has the weak negative spherical aberration of-0.1 micron - 0, and plays a role in compensating the positive spherical aberration of the human cornea. The intraocular lens comprises an anterior optical surface and a posterior optical surface, wherein at least one of the anterior optical surface and the posterior optical surface is an asphericoptical surface. The intraocular lens provided by the invention has better contrast sensitivity under a dark light condition (namely under a large-aperture diaphragm), and can improve the overall imaging quality of an intraocular lens eye under a real postoperative clinical condition.

The invention discloses a method for measuring the elasticity modulus of an in-vivo human cornea based on a jet-propelled optical coherence elasticity imaging technology. Doppler images of different cross sections of an in-vivo corneal tissue are acquired by using an optical coherence tomography (OCE) technology; elastic wave information in the cornea tissue is extracted through a human eye eyeball movement artifact correction algorithm; and the elasticity modulus of the cornea tissue is estimated according to a lamb wave model. Therefore, a problem that in-vivo human cornea elasticity imagingis difficult to realize through the existing OCE is solved.

According to embodiments, a membrane with a flat or curved surface is provided for protection of intraocular tissues. The membrane can be used to cover the cornea for protecting corneal endothelial cells, to cover the anterior and posterior surface of the iris, or to cover the surface of the posterior capsule for separating the intraocular tissues. The membrane has a layered structure, which is composed of a collagen and a hydrophilic biopolymer or an organic polymer material. In particular, the membrane has high transparency and high water retention in a wet state.

The invention provides a method for acquiring human corneal topography by using a trigonometric function, recursion and other mathematical methods. According to the method, concentric rings need to bedisplayed by an LCD display device, a cornea performs reflection and a camera performs receiving; and the x, y coordinates Xs, Ys of pixels on the LCD display device, the x, y coordinates Xc, Yc of the CCD, the x, y coordinates Xm, Ym of the human cornea as well as a distance from the midpoint of the display device and the pinhole of the camera to the vertex of the human cornea are known. According to a geometrical relationship of all the elements and assumption of forming of the cornea by a plurality of adjacent arcs, a curvature radius and a z coordinate of a first circular ring are obtained and then recursion is conducted in sequence to calculate the curvature radius and the z coordinate of the whole cornea, so that the terrain of the human cornea is obtained. According to the method,the accuracy of the human corneal topography is improved.

The invention is applicable to the field of medical equipment and instruments, and discloses a laser ophthalmic surgery system based on dual-mode image adjustment. The system comprises an optical fiber oscillator, a three-dimensional galvanometer scanning unit, a spectral domain optical coherence tomography unit, a sweep frequency optical coherence tomography unit, an optical fiber coupler, an optical guide unit, an image analysis processing unit and a control unit. According to the surgery system provided by the invention, a spectral domain optical coherence tomography optical path and a sweep frequency optical coherence tomography optical path form a pair of mutual cooperation structures through an optical fiber coupler, so that high-resolution clear image information from the corneas tothe fundus retinas can be quickly acquired; and laser pulse is accurately positioned in real time, and a new surgery scheme is made according to the acquired image information, so that the surgery accuracy and safety can be improved.

A telescope that provides for simultaneous clear viewing of objects or areas at various distances may be either Galilean or astronomical. The telescope may be mounted on or into any mechanism or device used for targeting or aiming. Such devices may include iron sights of small arms weapons, and cameras and telescopes, which may be either electrically or manually focused. These miniature scopes are engineered to maximize the clear depth-of-field viewing by the eye regardless of vision irregularities, such as Presbyopia, Myopia, Hyperopic, Astigmatism, or combinations of these, in conjunction with or without spectacle lens corrections. This aiming scope / device may be placed on a pair of spectacles in a very close proximity to the eye cornea. Other maximized scope image characteristics that occur are field-of-view, luminosity, and unmagnified and unbroken or distorted viewing field. Clearly detailed simultaneous viewing of images of all objects or areas at almost all distances forward of the objective lens is readily apparent to the scope user. Such objects include sighting devices forward of the scope on guns, bows, cameras, telescopes, and any target seen within the scope. Most reticles used in conjunction with this invention will also be observed in the scope.