41 results about "Atony" patented technology

The invention relates to a medicine composition, which is characterized by consisting of oxytocin analogue, ergometrine or salt acceptable in pharmacy, a carrier acceptable in preparation process or excipient, antioxygen, a potential of hydrogen (pH)conditioning agent, solubilizer and other auxiliary materials. The medicine composition is used for prevention and cure of postpartum hemorrhage caused by uterine contraction and atony and active management at the third stage of childbirth and is contribute to postpartum functional recovery. The ergometrine and the oxytocin analogue are combined to increase the curative effect and reduce the untoward effect. The dosage form is a freeze-drying mode or a sterile split package mode, high temperature sterilization is avoided in the preparation process, the medicines are stored in a solid state, the integrated antioxygen is added, impurities are decreased, the medicine composition is stable, and storage and transportation at the room temperature are facilitated.

The invention discloses a medicine for preventing and curing forestomach atony of ruminants, being prepared with the medicines according to a certain proportion: (fried) nuxvomica, areca seed, pharbitidis seed, euphorbia root, medicated leaven, hawthorn fruit, malt, Chinese rhubarb, mirabilite, stertite, antimony potassium tartrate and sodium bicarbonate, which (except mirabilite and stertite) are sun-dried, purified, crushed, and then grinded with two western medicines, sieved through an 80 to 100-mesh screen and finally mixed evenly. In clinical practice, the medicines are socked in boiled water for 30-60 minutes, of which the effective ingredients are dissolved and precipitated for improving the absorption rate of the medicine which is one-time drenched when cool. The medicine of the invention has quicker efficacy and smaller dosage compared with the single use of traditional Chinese medicine, longer maintenance time of drug effect and more difficult recurring compared with the single use of western medicine, and is difficult to develop the immunity to drugs, effectively releases or eliminates in vivo metabolic acidosis, greatly reduces death rate without a untoward reaction and with higher clinic cure rate. With simple preparation method and convenient use, the invention can be widely used in the breeding industry.

The invention relates to the technical field of Chinese medicaments, in particular to a medicament for treating cervical spondylosis. The medicament comprises the following raw materials in parts by weight: 80 to 120 parts of cassia twig, 100 to 180 parts of white peony root, 200 to 340 parts of kudzuvine root, 100 to 160 parts of Szechuan lovage rhizome, 80 to 120 parts of zedoary, 100 to 160 parts of rhizoma corydalis, 170 to 230 parts of fried jujube kernel, 170 to 220 parts of astragalus root, 90 to 150 parts of Chinese angelica, 170 to 210 parts of tuckahoe, 90 to 110 parts of bupleurum, and 80 to 130 parts of Baikal skullcap root. Based on the therapeutic principles of tonifying qi, activating blood, diffusing impediment and dredging collaterals, the medicament is suitable for treating the cervical spondylosis (nerve root type or vertebra artery type) caused by qi deficiency and blood stasis, is used for treating the symptoms such as arm numbness or disability, pains of neck, shoulders and arms, giddiness and headache, and is quick in response, good in curative effect and convenient to take.

The invention relates to a pharmaceutical composition for curing peripheral neuropathy of diabetes and a preparation method thereof. The composition of the invention mainly consists of Astragalus root, glossy privet fruit, cassia twig, radix paeoniae rubra, radix scutellariae, coptis root and leeches, is a medicine manufactured with a carrier or an exipient acceptable in pharmacy and in types of capsule, granule, tablet, soft capsule, guttate pill and the like. The composition of the invention has effects in supplementing qi, nourishing yin, detoxificating, dissolving the stagnant and activating channels, and is applicable to patients suffering from peripheral neuropathy of diabetes. The clinical research shows that the composition of the invention can obviously improve such symptoms of the patients suffering from peripheral neuropathy of diabetes as numbness of the limbs, sore limbs, warmlessness of acral, abnormal sensation, exhaustion and the like, as well as imposing an obvious improvement on nerve conducting speed and ending microcirculation. With the adoption of the composition of the invention, the sorbitol content in red blood cell decreases obviously, without any obvious untoward reaction.

The invention relates to a Chinese medicine preparation used for the treatment of the forestomach atony of milk cows, and a preparation method thereof. The Chinese medicine preparation is characterized in that the preparation comprises the following drugs according to parts by weight: 60 to150 portions of radix codonopsis pilosulae, 40 to 80 portions of tuckahoe, 40 to 80 portions of liquorice (roasted), 50 to 100 portions of radix puerariae, 20 to 40 portions of radix aucklandiae and 20 to 40 portions of rhizoma zingiberis. The preparation method is that: after being comminuted into ultra-micro powder, the drugs are evenly mixed according to proportion, or extracted by heating to make oral liquid, that is, prepared drug in pieces are weighted proportionally, then added with water 5 to 10 times more than the powder, dipped for 20 to 40 minutes, decocted for 50 to 80 minutes and filtered to be condensed to the drug content of 0.5g to 1g per milliliter, thus the Chinese medicine preparation is prepared. The Chinese medicine preparation of the invention has no residues and no toxic and side effects. The Chinese medicinal materials of the invention are comminuted in a super-micro way to be led to pass through a sieve of 100 meshes to 300 meshes, and plant cell walls are damaged to the maximum extent, thus overcoming the defects of the high content of crude fiber and the difficult stripping of active ingredients of Chinese medicine pulvis; the oral liquid is prepared by heating and extracting so as to ensure more convenient use and faster absorption and utilization, thereby being capable of effectively treating the forestomach atony of the milk cows.

The invention relates to a traditional Chinese medicine mixture for treating bovine forestomach atony and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine-based veterinary medicines. The traditional Chinese medicine mixture for treating bovine forestomach atony is prepared from the following raw materials in parts by weight: 12-20 parts of radix codonopsis, 15-18 parts of false chinese swertia herb, 12-18 parts of poria cocos, 15-22 parts of coriander, 11-15 parts of liquorice, 16-18 parts of herba lagotis, 15-18 parts of safflower, 12-20 parts of Chinese yam, 13-19 parts of charred triplet and 11-15 parts of dried ginger. The traditional Chinese medicine mixture for treating bovine forestomach atony is prepared from various Chinese herbs, and is reasonable in combination, free from toxic and side effects, capable of tonifying spleen and stomach, helping digestion and regulating the flow of qi, and also capable of effectively treating diseases caused by forestomach atony such as drink desire reduction, insufficient rumination, sour belching, and light and white mouth; the pure traditional Chinese herbs are pollution-free and more beneficial for healthy growth of the livestock.

The invention relates to a Chinese medicinal preparation for preventing and treating atony of forestomach of dairy cows and a preparation method thereof and belongs to the technical field of Chinese veterinary medicaments. The Chinese medicinal preparation relates to the following main compositions: codonopsis pilosula, largehead atractylodes rhizome, dry ginger, liquoric root, tangerine peel, common yam rhizome, hawthorn and pine twig powder, wherein the codonopsis pilosula, the largehead atractylodes rhizome, the liquoric root and the common yam rhizome have the effects of tonifying spleen and reinforcing stomach; the tangerine peel has the effects of diminishing bloat and regulating vital energy; and the dry ginger has the effects of warming center and dissipating cold. The medicaments are used together and have the effects of tonifying spleen and reinforcing stomach, helping digestion and regulating vital energy, and the pine twig powder is added to supplement various vitamins and trace elements at the same time. The Chinese medicinal preparation is safe, does not have toxic or side effects, is suitable for all the growth periods of the dairy cows and particularly can solve the problem of antibiotic milk in lactation periods, and the treatment and production are not mutually influenced. The Chinese medicinal preparation has high practicality and a wide application range, and clinical trials prove that the Chinese medicinal preparation can effectively treat the atony of forestomach of the dairy cows and complications thereof.

The invention discloses a medicament for treating atony of forestomach in sheep, prepared from the following raw materials in weight: 20g of roasted malt, 20g of medicated leaven, 15g of costus root, 20g of officinal magnolia bark, 20g of betel palm, 20g of tuckahoe, 10g of corydalis root, 20g of angelica, 20g of bighead atractylodes rhizome, 20g of Chinese atractylodes, 15g of dried orange peel, 20g of mirabilite, 10g of licorice and 30g of rhubarb. The medicament disclosed by the invention has easy availability of raw materials, is simple to prepare, and has the efficacies of strengthening the spleen, regulating the flow of qi, promoting digestion, resolving food stagnancy and enhancing gastrointestinal peristalsis.

The invention features polypeptides that include an extracellular ActRIIB variant. In some embodiments, a polypeptide of the invention includes an extracellular ActRIIB variant fused to an Fc domain monomer or moiety. The invention also features pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions involving weakness and atrophy of muscles, bone damage, low red blood cell levels (e.g., anemia or blood loss), fibrosis, and / or pulmonary hypertension.

The present invention provides a method of treating a disorder associated with muscle weakness in a subject, comprising administering to the subject a controlled-release composition comprising an effective amount of ribitol and / or ribose, thereby treating the disorder associated with muscle weakness.

Composition comprising at least two components, more preferably at least three components, more preferably at least four components, selected from the group of (i) a nucleoside equivalent, (ii) an ω-3 polyunsaturated fatty acid selected from the group of DHA, DPA and EPA, (iii) a vitamin B, (iv) a phospholipid, (v) an antioxidant and (vi) a choline, with the proviso that at least component (i) or (iii) is present, for use in the prevention or treatment of frailty in a mammal, wherein frailty is determined by compliance with at least 2 criterions, preferably 3 criterions, selected from the group of muscle weakness, excessive feelings of exhaustion or fatigue, abnormally low physical activity, slow or unsteady gait, weight loss, and neurological dysfunction.

This invention relates to selective m1 muscarinic agonist, their use or a formulation thereof in the treatment of glaucoma and / or other conditions which are related to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans. In addition, the present invention relates to the use of the compounds in the treatment of dementia such as Alzheimer's disease and vascular dementia, depression, attention deficit disorder, sleep disorder, schizophrenia, pain, ischemia, atrophic gastritis, and atony of gastrointestinal tract.

The present invention relates to ALK5 inhibitors and their uses as skeletal muscle hypertrophy inducers as well as to promote skeletal muscle regeneration, to prevent skeletal muscle atrophy, or in the treatment or prevention of a disease or injury resulting in loss of skeletal muscle tissue and / or muscle weakness. It further relates to the non-therapeutic use of such compounds to increase musclemass, muscle strength and / or muscle performance in a subject.

The present disclosure relates generally to methods of restoring neuromuscular transmission by locally administering an effective dose of a composition comprising an anticholinesterase to a non-responsive muscle. The disclosure also relates to methods of reversing a neurotoxin-induced muscle paralysis or muscle weakness, the method comprising locally administering a composition comprising an anticholinesterase to the patient.

The present disclosure relates to a composition for preventing and treating a muscular disease, or improving muscular function, which contains Cudrania tricuspidata such as a pulverization product or an extract of Cudrania tricuspidata as an active ingredient. The Cudrania tricuspidata according to the present disclosure such as the pulverization product or extract of Cudrania tricuspidata has an effect of increasing the activity of mTOR, which is involved in muscle protein synthesis, and reducing the mRNA expression of MuRF-1 and atrogin-1, which are involved in muscle protein degradation, increases muscle mass and improves muscular function. Therefore, it may be usefully utilized in the prevention, alleviation or treatment of various muscular diseases such as atony, muscular atrophy, muscular dystrophy, muscle degeneration, muscle weakness, cachexia, sarcopenia, etc.

Lumbar diseases are frequently-occurring diseases, common waist soreness and leg pain, rear waist soreness, even lower limb weakness, limb numbness and other symptoms, seriously affect normal work and life of patients, even can cause serious lesions due to spinal canal hyperosteogeny, and enable the patients to lose normal working ability. In order to solve the problems, the invention provides a waist load reducing device which is convenient to use and good in air permeability, further supports the weight of the upper body of a user, effectively reduces the pressure on the lumbar vertebra in the long-time sitting process, indirectly draws the lumbar vertebra and is not influenced when the user stands up at any time.

The invention provides a traditional Chinese medicine composition for treating neurasthenia. The raw materials of the traditional Chinese medicine composition are composed of xylitol, ginseng, semen cuscutae, epimedium, morinda officinalis, cistanche, eucommia bark, honeysuckle, semen cassiae, wallich and talcum powder. The traditional Chinese medicine composition has a certain therapeutic effect in treating hypertension, myocardial dystrophy, coronary sclerosis, angina pectoris and the like and can alleviate various symptoms. By the traditional Chinese medicine composition, the stomachache of patients suffering from the chronic gastritis disappears, and the appetite thereof is enhanced. Meanwhile, the stools of patients suffering from the chronic gastritis are normal and the total acidity of the gastric juice thereof is increased. For asthenic type psychiatric patients, asthenic and depressive type psychiatric patients, schizophrenia patients, psychiatric patients caused by poisoning and infectious diseases, degenerative type psychiatric patients and the like, the above traditional Chinese medicine composition has therapeutic effects. The traditional Chinese medicine composition has a significant excitatory effect on the nervous system. The traditional Chinese medicine composition improves the action performances of a human body, reduces the fatigue, eliminates or relieves the symptoms of general weakness, headache, insomnia and the like, and nourishes the vigour.

The present invention relates to a composition and a kit for diagnosis of muscle weakness-related disease, which comprises agents for measuring the expression levels of gelsolin and tetranectin, and to a method of diagnosing muscle weakness-related disease by using the same. The composition, kit and method for diagnosis of muscle weakness-related disease according to the present invention make it possible to diagnose muscle weakness-related disease in an easy and rapid manner by molecular diagnosis, thereby systemically managing the muscle weakness-related disease while increasing therapeutic efficacy against the muscle weakness-related disease.

The invention discloses a Chinese medicinal composition for treating cattle forestomach atony, which is prepared from the following raw materials in part by weight: 50 parts of astragalus, 50 parts of pilose asiabell root, 60 parts of ficus simplicissima lour, 60 parts of Philippine flemingia root, 20 parts of prepared common monkshood daughter root, 20 parts of blast-fried dried ginger, 20 partsof cassia bark, 20 parts of combined spicebush root, 20 parts of bitter orange, 15 parts of areca seed, 30 parts of avicennia pricklyash root, 30 parts of witchweed, 20 parts of thickleaf croton root, 80 parts of raw hawthorn fruit, 30 parts of round cardamom fruit, 50 parts of stir-fried radish seed, 30 parts of costustoot and 20 parts of honey-fried liquoric root. The composition is readily available in medicine source, low in price, obvious in effect and high in cure rate, cattle forestomach atony is quickly cured and is difficult to relapse after being cured, the effective rate of treating cattle forestomach atony is 100 percent, and the cure rate is 100 percent.

The invention discloses a dexpanthenol infusion preparation and a preparation method thereof. The infusion is prepared from an active ingredient of dexpanthenol and an isotonic solvent with a certain pH value through high-temperature sterilization. The research of the new preparation successfully solves the secondary pollution problem in the use process of medicines so that the clinical application of the dexpanthenol is safer, highly efficient and more convenient. The infusion used as a preventive agent can reduce the possibility of generating paralytic ileus after a larger abdomen surgical operation and can be used for abdominal distension caused by intestinal weakness, postoperative or puerperal flatus or postoperative delay of intestinal motility recovery, and the like.

The invention belongs to the technical field of traditional Chinese medicine, and specially relates to a traditional Chinese medicine composition for treating forestomach atony of goat and a preparation method thereof. Based on the properties, bighead atractylodes rhizome, camphor tree seeds, cherokee rose-hip, folium artemisia argyi, and dried orange peel are reasonably compounded. The camphor tree seeds and cherokee rose-hip are main components. Through reasonable compounding and processing, functions of camphor tree seeds are fully exerted such as wind dispelling, cold dispelling, qi moving, pain relieving, resuscitation inducing, swelling eliminating, dampness removing, and the like. Cherokee rose-hip has the functions of relieving diarrhea with astringents, astringing qi, invigoratingspleen, boosting qi, removing dampness in spleen and stomach, removing heat in stomach, strengthening spleen and stomach, and promoting appetite. Folium artemisia argyi and dried orange peel coordinate the nature of drugs. The traditional Chinese medicine composition can treat forestomach atony of goat and promotes the appetite of goats. The traditional Chinese medicine composition is made of pure Chinese herbals, does not contain any chemical product, and does not influence the health of goat.

The invention relates to the technical field of Chinese medicaments, in particular to a medicament for treating cervical spondylosis. The medicament comprises the following raw materials in parts by weight: 80 to 120 parts of cassia twig, 100 to 180 parts of white peony root, 200 to 340 parts of kudzuvine root, 100 to 160 parts of Szechuan lovage rhizome, 80 to 120 parts of zedoary, 100 to 160 parts of rhizoma corydalis, 170 to 230 parts of fried jujube kernel, 170 to 220 parts of astragalus root, 90 to 150 parts of Chinese angelica, 170 to 210 parts of tuckahoe, 90 to 110 parts of bupleurum, and 80 to 130 parts of Baikal skullcap root. Based on the therapeutic principles of tonifying qi, activating blood, diffusing impediment and dredging collaterals, the medicament is suitable for treating the cervical spondylosis (nerve root type or vertebra artery type) caused by qi deficiency and blood stasis, is used for treating the symptoms such as arm numbness or disability, pains of neck, shoulders and arms, giddiness and headache, and is quick in response, good in curative effect and convenient to take.