43results about How to "Reduce visceral fat" patented technology

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. They are useful as agonists of the androgen receptor in bone and / or muscle tissue while antagonizing the AR in the prostate of a male patient or in the uterus of a female patient. These compounds are therefore useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive impairment, decreased libido, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal adiposity, metabolic syndrome, type II diabetes, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

The invention discloses a strain for preventing and treating metabolic diseases and application for the strain. The strain is Akkermansia muiniphila strain which is named Akkermansia muciniphila SSYD-3 and has the preservation number being CGMCC No.14764. Compared with the existing Ackermann muiniphila strain ATCC BAA 835, the Akkermansia muiniphila strain provided by the invention is more ideal in fermentation performance, storage stability, acid resistance, bile salt tolerance and the effect of treating the metabolic diseases.

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal adiposity, metabolic syndrome, type II diabetes, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

Compounds of structural formula (I) are modulators of the androgen receptor (AR) in a tissue selective manner. They are useful as agonists of the androgen receptor in bone and / or muscle tissue while antagonizing the AR in the prostate of a male patient or in the uterus of a female patient. These compounds are therefore useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive impairment, decreased libido, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

The present invention has its object to provide an agent for preventing and / or ameliorating life style-related diseases which contains, as an active ingredient, a substance derived from a safe food material having a long history of being eaten as a food and which is capable of being utilized as functional foods such as health foods or functional health foods (specific health foods, functional nutritive foods). The agent for preventing and / or ameliorating life style-related diseases according to the invention contains, as an active ingredient, at least one compound selected from the group consisting of ar-turmerone, +--turmerone, -turmerone, curlone, bisacumol and -sesquiphellandrene, or at least one compound selected from among the bisabolane type sesquiterpenoids derived from Curcuma longa L., and therefore is useful for preventing and / or ameliorating diabetes, visceral fat obesity, metabolic syndrome and obesity, among others.

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. They are useful as agonists of the androgen receptor in bone and / or muscle tissue while antagonizing the AR in the prostate of a male patient or in the uterus of a female patient. These compounds are therefore useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive impairment, decreased libido, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

The invention discloses a traditional Chinese medicine prescription for treating an overweight / obesity type polycystic ovary syndrome. A basic prescription is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10 to 30 parts of radix codonopsis, 5 to 15 parts of bighead atractylodes rhizome, 5 to 15 parts of poria cocos, 3 to 9 parts of cassia twig, 3 to 9 parts of radix et rhizoma rhei, 5 to 15 parts of herba artemisiae capillariae, 5 to 15 parts of rhizoma alismatis, 5 to 15 parts of rhizoma sparganii, 5 to 15 parts of rhizoma curcumae, 5 to 15 parts of herba epimedii and 3 to 6 parts of prepared liquorice root. The traditional Chinese medicine prescription disclosed by the invention has refined compatibility and basic traditional Chinese medicineraw materials are adopted; metabolism and reproductive-endocrine disorder are considered, the difficult of researching and developing overweight / obesity type polycystic ovary syndrome medicines at present is smoothly solved and a satisfied curative effect is obtained. The prescription is a traditional Chinese medicine compound prescription considering the metabolism and the reproductive-endocrinedisorder; the prescription is simple and the effect is clear; the prescription has a wide popularization prospect in clinical application, and is prepared into various Chinese patent drugs with different preparations so that the prescription is more convenient for patients; the total cost is low so that the financial burden of the patients can be alleviated to the great extent and the medical burden of China is alleviated to a certain extent.

The invention aims to provide a preparation method of multifunctional cooking oil. The method is characterized by adding lipase into mixed oil with animal oil and vegetable oil to accelerate generation of diglyceride. The cooking oil is rich in various nutritional components such as saturated fatty acid, monounsaturated fatty acid, polyunsaturated fatty acid and diglyceride, and has functions of balancing nutrition value and protecting health.

Compounds of formula I are modulators of the androgen receptor (AR) in a tissue-selective manner. These compounds are used alone or in combination with other active agents for the enhancement of attenuated muscle tone and for the treatment of conditions caused by androgen deficiency or ameliorated by the administration of androgens, including osteoporosis, osteopenia, glucocorticoid-induced bone osteoporosis, periodontal disease, fractures, bone damage after bone reconstruction surgery, sarcopenia, fragility, skin aging, male hypogonadism, postmenopausal symptoms in women, arteriosclerosis, hypercholesterolemia, hyperlipidemia, Obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal fat, metabolic syndrome, type II diabetes, cancer Cachexia, Alzheimer's disease, muscular dystrophy, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune diseases.

The invention relates to substituted N-(4-oxo-3,4-dihydroquinazolin-2-yl)butanamid derivatives which modulate androgen receptors to treat conditions such as: osteoporosis, peridontal disease, bone fracture, frailty, and sarcopenia.

The invention relates to the field of biology, and discloses a composition for reducing visceral fat based on microencapsulated red yeast rice and a preparation method thereof. The composition includes microencapsulated red yeast rice, natto, green tea extract, mulberry leaf extract and purple Su oil; the microencapsulated red yeast rice includes a core material and a capsule material; the core material includes a red yeast pigment or a mixture of a red yeast pigment and a red yeast rice. In the present invention, microencapsulated red yeast rice, natto, green tea extract, mulberry leaf extract and perilla oil are compounded, and the red yeast rice is prepared into microcapsules by using microencapsulation technology. Oxidation occurs due to the influence of various factors. On the other hand, microencapsulation is beneficial to improve the taste of the product and enable the slow release of active substances.

The invention relates to the technical field of microbial fermentation, and discloses a monascus purpura, a fermentation method and an application of a fermentation product in preparing products for reducing visceral fat. The invention provides a strain of Monascus purpura ( Monascus purpureus ) SHM1105, the strain is preserved in the General Microbiology Center of the China Committee for the Collection of Microbial Strains, with the preservation number CGMCC No.15369, and the preservation date is March 21, 2018. By optimizing the fermentation method of the strain, the monascus pigment of the strain was prepared. Through animal experiments, the monascus pigment obtained through the optimized fermentation method not only has the advantage of high color value, but also has the effect of reducing Cholesterol, weight loss, lower visceral fat function.

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.