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Medicinal composition with antioxidant activity and blood vessel and blood cleaning antioxidant and/or protective agent

An anti-oxidant activity and anti-oxidant technology, applied in the direction of drug combination, anti-toxic agent, cardiovascular system diseases, etc., can solve the problems of low bioavailability, insoluble, unfavorable digestion and absorption, etc., and achieve easy digestion and absorption without adverse stimulation Response, effect of increasing bioavailability

Inactive Publication Date: 2011-04-27
张家港天乙传统医药研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such as proanthocyanidin (OPC) extracted from grapes, pine flowers, lemons and other fruits and plants, its ability to scavenge free radicals is 20 times that of vitamin C. This proanthocyanidin (OPC) is a unique Bioflavonoids are easy to dissolve in water, but when they are taken orally into the stomach and contact with gastric juice and digestive juice, OPC powder will form a gel, which is difficult to dissolve, and only a small part is dissolved, which is not conducive to digestion and absorption, so the bioavailability is low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] This embodiment provides a pharmaceutical composition with anti-oxidative activity, and its raw material composition is as follows: 10 parts of grape seeds; 80 parts of fresh apples; 40 parts of cranberries; 90 parts of pine flowers; 20 parts of lemons; 25 parts; 25 parts of mulberry; 30 parts of wolfberry; 15 parts of Codonopsis; 30 parts of rhodiola; 90 parts of glutinous rice bran;

[0018] The preparation method of the pharmaceutical composition is as follows:

[0019] (1) Weigh grape seeds, fresh apples, lingonberries, lemons, mulberries and wolfberries in proportion, crush them, add 30 times of water, stir evenly to obtain a water dispersion, concentrate at room temperature with a membrane concentration system, and use membrane selection control The molecular weight is less than 10,000, and the volume of the concentrated solution is about 5% of the volume of the aqueous dispersion. The particles are prepared by spray drying, and vacuum-dried below 65°C until the m...

Embodiment 2

[0023] The present embodiment provides a pharmaceutical composition with anti-oxidative activity, and its raw material composition is as follows: 40 parts of grape seeds; 60 parts of fresh apples; 60 parts of cranberries; 90 parts of pine flowers; 20 parts of lemons; 25 parts; 10 parts of mulberry; 15 parts of wolfberry; 15 parts of Codonopsis; 30 parts of rhodiola; 90 parts of glutinous rice bran;

[0024] The preparation method of the pharmaceutical composition is as follows:

[0025] (1), weigh grape seeds, fresh apples, lingonberries, lemons, mulberries and wolfberries in proportion, crush them, add 20 times of water, stir evenly to obtain a water dispersion, concentrate with a membrane concentration system at room temperature, and use membrane selection control The molecular weight is less than 10,000, and the volume of the concentrated solution is about 5% of the volume of the aqueous dispersion. The particles are prepared by spray drying, and vacuum-dried below 65°C unt...

Embodiment 3

[0029] The present embodiment provides a pharmaceutical composition with anti-oxidative activity, and its raw material composition is as follows: 40 parts of grape seeds; 60 parts of fresh apples; 60 parts of cranberries; 100 parts of pine flowers; 20 parts of lemons; 5 parts; 10 parts of mulberry; 15 parts of wolfberry; 15 parts of Codonopsis; 40 parts of rhodiola; 90 parts of glutinous rice bran;

[0030] The preparation method of the pharmaceutical composition is the same as in Example 2.

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PUM

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Abstract

The invention discloses a medicinal composition with antioxidant activity and a blood vessel and blood cleaning antioxidant and / or protective agent. The medicinal composition comprises the following raw materials in part by weight: 1 to 60 parts of grape seed, 10 to 200 parts of fresh apple, 5 to 80 parts of blueberry, 10 to 200 parts of piny flower, 5 to 60 parts of lemon, 20 to 80 parts of hawthorn, 5 to 50 parts of purple salvia miltiorrhiza, 5 to 50 parts of mulberry, 10 to 50 parts of Chinese wolfberry, 10 to 50 parts of codonopsis pilosula, 10 to 50 parts of rhodiola, 50 to 200 parts of glutinous rice bran; 5 to 50 parts of epimedium herb and 1 to 10 parts of zinc gluconate or ferrous gluconate or a mixture of the zinc gluconate and the ferrous gluconate. The invention has high bioavailability, is easily digested and absorbed, has no pessimal stimulation to gastrointestinal tracts, and can exert the effect of primary anthocyanidin extracted from different plants and plant seeds to the greatest degree.

Description

technical field [0001] The present invention relates to a pharmaceutical composition with antioxidant activity and the blood vessel and blood cleaning antioxidant and / or protective agent using the pharmaceutical composition as an active ingredient. Background technique [0002] More and more studies have proved that free radicals are the main culprit in promoting human aging. Modern medical research shows that free radicals can directly cause more than 100 common diseases that endanger health, including heart disease, cancer and arthritis. Proanthocyanidins extracted from plants and plant seeds have strong antioxidant properties and can quickly remove free radicals in the human body. Such as proanthocyanidin (OPC) extracted from grapes, pine flowers, lemons and other fruits and plants, its ability to scavenge free radicals is 20 times that of vitamin C. This proanthocyanidin (OPC) is a unique Bioflavonoids are easy to dissolve in water, but when they are taken orally into ...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P9/14A61P39/06A61K31/191
Inventor 苏朝品叶雁波
Owner 张家港天乙传统医药研究院有限公司
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