The invention discloses a medical image zero-watermark embedding method and device based on NSCT combination transformation, equipment and a readable storage medium. The scheme is implemented on the basis of hybrid transformation and Arnold transformation of NSCT, RDWT and DCT, and in the watermark embedding process, firstly, a more robust medical image feature vector is extracted in combination with the NSCT, the RDWT and the DCT so as to resist geometric attacks. Secondly, the watermark is encrypted by utilizing Arnold transformation, so that the security of watermark information is enhanced; and finally, watermark embedding is realized by using a zero watermark technology, so that the integrity, the watermark capacity and the invisibility of the medical image are ensured, the defect oforiginal image data modification caused by a traditional watermark embedding technology is avoided, and the quality of the medical image is ensured. Therefore, even if the patient information is attacked intentionally or unintentionally, the medical image and the watermark cannot be cracked as long as the unauthorized user does not know the secret key, so that the personal information of the patient is truly protected.