41results about How to "Mitigate prospect" patented technology

An implantable prosthesis for repairing an anatomical defect, such as a soft tissue and muscle wall defect. The prosthesis is configured to reduce the likelihood that an applied force at the repair site, such as due to intraabdominal pressure or tissue shrinkage, can lead to detrimental effects associated with tension at the anchoring locations between the prosthesis and host tissue and / or contraction of the prosthesis. In this regard, the prosthesis may be configured to limit the amount of tension at the anchoring locations caused by the application of a force or pressure to the prosthesis and / or contraction of the prosthesis. Alternatively, the prosthesis may be configured to compensate for contraction of the prosthesis due to tissue shrinkage at the repair site. The prosthesis may be configured to both limit tension at the anchoring locations and compensate for tissue shrinkage. The prosthesis may facilitate a reduction in postoperative discomfort, a recurrence of the defect, or the creation of a new defect associated with tension and / or prosthetic contraction.

A data processing apparatus and method are provided for performing address translation in response to a memory access request issued by processing circuitry of the data processing apparatus and specifying a virtual address for a data item. Address translation circuitry performs an address translation process with reference to at least one descriptor provided by at least one page table, in order to produce a modified memory access request specifying a physical address for the data item. The address translation circuitry includes page table walk circuitry configured to generate at least one page table walk request in order to retrieve the at least one descriptor required for the address translation process. In addition, walk ahead circuitry is located in a path between the address translation circuitry and a memory device containing the at least one page table. The walk ahead circuitry comprises detection circuitry used to detect a memory page table walk request generated by the page table walk circuitry of the address translation circuitry for a descriptor in a page table. In addition, the walk ahead circuitry has further request generation circuitry which is used to generate a prefetch memory request in order to prefetch data from the memory device at a physical address determined with reference to the descriptor requested by the detected memory page table walk request. This prefetched data may be another descriptor required as part of the address translation process, or may be the actual data item being requested by the processing circuitry. Such an approach can significantly reduce latency associated with the address translation process.

Methods and compositions for treating inflammatory bowel disease involve the use of targeted antibiotics in combination with probiotic formulations. The probiotics mitigate many of the deleterious side effects associated with antibiotic use and permit the antibiotic to be administered at a higher dose and for a longer duration than would otherwise be possible in the absence of the probiotic. The practice of the invention may reduce or eliminate the use of immunosuppressants in the treatment and management of IBD.