110results about How to "Limited effectiveness" patented technology

The invention relates to a double-stranded compound, preferably an oligoribonucleotide, which down-regulates the expression of a human p53 gene. The invention also relates to a pharmaceutical composition comprising the compound, or a vector capable of expressing the oligoribonucleotide compound, and a pharmaceutically acceptable carrier. The present invention also contemplates a method of treating a patient suffering from alopecia or acute renal failure or other diseases comprising administering to the patient the pharmaceutical composition in a therapeutically effective dose so as to thereby treat the patient. The alopecia may be induced by chemotherapy or radiotherapy, and the patient may be suffering from cancer, in particular breast cancer.

Improved methods of treating water and hydrocarbons producing subterranean formations to reduce the water permeabilities of the formations without substantially reducing the hydrocarbons permeabilities thereof are provided. The methods basically comprise introducing into the formation a chemical which does not resist water flow and attaches to adsorption sites on surfaces within the porosity of the formation but slowly washes off the sites as another fluid flows through the treated formation. Thereafter, a water flow resisting polymer is introduced into the formation so that it flows deeply into the porosity of the formation before the previously introduced chemical washes off and attaches to the adsorption sites as the chemical washes off.

Provided is a methodology and system for applying coatings onto the interior surfaces of components. The approach comprises a vapor creation device (for example an electron beam or laser that evaporates a single or multiplicity of solid or liquid sources), a vacuum chamber having a moderate gas pressure (between about 10⁻⁴ to about 10³ Torr) and a inert gas jet having controlled velocity and flow fields of gas jet. The gas jet is created by a rarefied, inert gas supersonic expansion through a nozzle. By controlling the carrier gas flow into a region upstream of the nozzle an upstream pressure is achieved (i.e. the gas pressure prior to its entrance into the processing chamber through the nozzle). The carrier gas flow and chamber pumping rate control the downstream (or chamber) pressure (i.e., downstream of the nozzle). The ratio of the upstream to downstream pressure along with the size and shape of the nozzle opening controls the speed of the gas entering the chamber. The carrier gas molecular weight (compared to that of the vapor) and the carrier gas speed controls its effectiveness in redirecting the vapor atoms via binary collisions towards the substrate. The speed and flux of the atoms entering the chamber, the nozzle parameters, and the operating chamber pressure can all vary leading to a wide range of accessible processing conditions. Vapor created from a source is transported into the interior regions of a component using binary collisions between the vapor and gas jet atoms. Under certain process conditions these collisions enable the vapor atoms to scatter onto the interior surfaces of the component and deposit.

A vehicle turn signaling apparatus includes a light source that is powered by a turn signal circuit of the vehicle. The light source is configured to project a low divergence visible line onto a driving lane adjacent to the vehicle in response to activation of the turn signal circuit to visibly warn other drivers where a driver of the vehicle may intend to move the vehicle.

Method for measuring weekly and annual emissions of a greenhouse gas generated over a determined geographical area and measuring system implementing the method.

An approach for the treatment of surfaces in public places with ultraviolet light is disclosed. In one embodiment, a disinfection illuminator having ultraviolet radiation sources can irradiate a number of contact surfaces. A control unit can control the ultraviolet irradiation of the contact surfaces. The disinfection illuminator is suitable for a wide variety of devices that are used by the general public. Gas station pumps, door knobs, key pads, and bathrooms are illustrative of examples of some devices and places having commonly-used surfaces that can be treated by the disinfection illuminator.

An ultraviolet flux multiplying air sterilization chamber comprises inner surfaces having a diffuse reflective behavior. The sterilization chamber includes an inlet aperture and an outlet aperture for air to flow through said chamber and a light source emitting an ultraviolet light. Due to the reflectivity of the inner surfaces of the chamber, a flux of the ultraviolet light is multiplied by reflecting multiple times from the inner surfaces of the chamber. The inlet and outlet apertures are advantageously configured to reduce the amount of light that escapes from the chamber and increase the amount of photons available in the chamber. In an exemplary embodiment, perforated end panels having diffuse, reflective interior surfaces may be provided over at least a portion of the inlet and outlet apertures.

A fabric and method to support garments comprising opaque heat-moldable circular knit fabrics having relatively high amounts of spandex material as well as sufficient amounts of other fibers to simultaneously provide maximum support and maximum comfort to a wearer and which can be easily molded to the specifications of a wearer's body dimensions. Such high-spandex content, moldable garment fabrics are novel to the industry since the permissible added amount of spandex within such fabrics has been limited due to the power, modulus strength, and elongation of such fibers. Furthermore, the ability to provide moldable, high-spandex circular knit fabrics has been limited, if not impossible, due to the above-noted characteristics of the spandex fibers themselves. The inventive moldable fabrics and garments provide such desirable spandex properties while also increasing the comfortability to the wearer. The method of producing such fabrics is also contemplated within this invention. Both the fabric and the method state that the amount of spandex in the fabric is at least 24% of the total fiber weight in the fabric.

An in situ soil remediation system may be used to remove or reduce levels of mercury contamination within soil. The soil remediation system may also remove or reduce levels of other contaminants within the soil. Mercury may be vaporized within the soil by a heating system. The vaporized mercury may be removed from the soil by a vacuum system. The vaporized mercury may pass through heated risers that elevate the vaporized mercury. After the vaporized mercury passes from the heated risers, the vaporized mercury may be allowed to cool, condense, and flow downward to a treatment facility. Removing mercury from the soil as a vapor may provide an economical, safe, and efficient way to remediate mercury contaminated soil.

This invention relates to a method of reducing cardiovascular morbidity and mortality in a prediabetic or Type 2 Diabetes patient population. The method comprises administering an effective dosage of a long acting insulin, preferably insulin glargine, to a prediabetic or Type 2 Diabetes patient.

A user interface, telephony device, and method for managing user control settings associated with a telephony device is described. The user interface displays a label array on a display device of the telephony device. The label array includes at least one row of labels, each representing a discrete function or feature associated with the telephony device. A button array is provided in the vicinity of the display device. The button array includes a corresponding row or rows of buttons, each button representing a discrete function or feature for the telephony device and corresponding to a label within the label array. One or more buttons in the button array are selectively illuminated to indicate a status of one or more functions or features associated with one or more labels in the label array.

The subject of the invention is an anode block (13, 13a-13e) made of carbon for a pre-baked anode (4) for use in a metal electrolysis cell (1) comprising a higher face (24), a lower face (23), designed to be laid out opposite a higher face of a cathode (9), and four side faces (21,22,34), and including at least one first groove (31a-31e) leading onto at least one of the side faces, in which the first groove has a maximum length L_max in a plane parallel to the lower face, and characterized in that the first groove does not lead onto said lower or higher faces, or leads onto said lower or higher faces over a length L₀ less than half the maximum length L_max.

An open mesh insect control material is described which includes an insect contact surface, an internal surface, apertures communicating both surfaces and a plurality of filamentous projections protruding from the insect contact surface the projections at least partly occlude the apertures. The structure is suitable for use in pest control especially as a mosquito net.

A method of fracking carbonate-rich reservoirs, comprising injecting a cryogenic or chilled fluid followed by an acid into said reservoir, allowing the acid to etch said reservoir, and thereby increasing production of a fluid, such as water, oil or gas, from said reservoir.