The invention discloses an intelligent substation comprehensive monitoring system based on Beidou Internet of Things. The system comprises a monitoring main station and a monitoring station end, and the monitoring main station communicates with the monitoring station end through a Beidou communication system. The monitoring station end integrates transformer oil chromatography monitoring data, a transformer iron core grounding current, transformer infrared temperature measurement data, switch mechanical characteristic information, partial discharge information in a transformer and a switch cabinet, a temperature and humidity in the switch cabinet, a cable joint temperature, cable joint ultraviolet monitoring data, cable interlayer water immersion information, lightning arrester monitoringdata, a grounding point grounding resistance and the temperature and humidity of each power distribution chamber in a substation so as to realize all-weather full-coverage state monitoring on a main electrical equipment working condition, an electrical equipment surrounding environment and an electrical equipment safety protection condition of the substation. Linkage control is carried out on power equipment defects, abnormal information alarm and front-end alarm so that safety of power grid operation is improved, labor intensity of front-line personnel is reduced, and an enterprise operationbenefit is improved.