32results about How to "Cheap and easy to obtain" patented technology

Disclosed in the present disclosure are a crystal form of a dihydropyrido ring compound, and preparation method and intermediate thereof.

A method for providing lubricity in fuels and lubricants includes adding a boron compound to a fuel or lubricant to provide a boron-containing fuel or lubricant. The fuel or lubricant may contain a boron compound at a concentration between about 30 ppm and about 3,000 ppm and a sulfur concentration of less than about 500 ppm. A method of powering an engine to minimize wear, by burning a fuel containing boron compounds. The boron compounds include compound that provide boric acid and / or BO3 ions or monomers to the fuel or lubricant.

A process for curing photopolymer which comprises exposing the photopolymer to an image produced by a mask-free imaging apparatus. The image may be generated by a monochromatic display screen, e.g. a liquid crystal display, light emitting diodes, a cathode ray tube or plasma screen.

Provided is a light-switchable gene expression system, comprising: a) a recombinant light-switchable transcription factor-encoding gene, said recombinant light-switchable transcription factor comprising a first polypeptide as the DNA bonding domain, a second polypeptide as the photosensitive domain, and a third polypeptide as the transcription regulatory domain; b) a target transcription unit comprising at least one reaction element recognized and bound by the first polypeptide, a promoter regulated by the third polypeptide and a nucleotide sequence to be transcribed. Also provided is an eukaryotic expression vector comprising said light-switchable gene expression system, and a method for regulating gene expression in a host cell by using the light-switchable gene expression system. Also provided is a reagent kit containing different elements of the light-switchable gene expression system. The light-switchable gene expression system has a quick, effective and powerful induction with little or no toxicity. It is safer than other inducers, and can spatiotemporally control gene expression.

The present invention relates to a LED (light-emitting diode) phosphor and fabricating method thereof, and particularly relates to a LED phosphor having a light-emitting thin film (or photoluminescence thin film) made of an organic material and a zinc oxide microstructure (or nanostructure) and a method for fabricating the LED phosphor by hydrothermal method and combination of the organic material and the zinc oxide microstructure (or nanostructure). In this invention, the light-emitting thin film (or photoluminescence thin film) made of the organic material and the zinc oxide microstructure (or nanostructure) is applied instead of rare earth elements to fabricate the LED phosphor. Therefore, the cost of the LED phosphor and the white LED can be reduced and the processes for fabricating the LED phosphor and the white LED can be simplified.

Provided is an optically controlled gene expression system of prokaryotic bacterium, comprising: a) a photosensitive recombinant transcription factor encoding gene, the photosensitive recombinant transcription factor is one fusion protein comprising a first polypeptide as the DNA bonding domain and a second polypeptide as the photosensitive domain; b) a target transcription unit comprising promoter or promoter-reaction element or reaction element-promoter containing at least one reaction element recognized / bound by the first polypeptide and the nucleic acid sequence to be transcribed. Also provided is a prokaryotic expression vector comprising said optically controlled gene expression system, and a method for regulating gene expression in a prokaryotic host cell by using the optically controlled gene expression system. Also provided is a reagent kit containing different components of the optically controlled gene expression system. The optically controlled gene expression system of prokaryotic bacterium has a quick, effective and powerful induction, is safer than other inducers, is of little or no toxicity, and can control gene expression both spatially and temporally, and can regulate many life processes of prokaryotic bacterium.

A method of preparing β-hydroxycarboxylic acid ester comprises mixing an alkylene oxide, a monohydric alcohol and a composite catalyst, and performing a carbonylation esterification reaction in a carbon monoxide atmosphere to obtain the β-hydroxycarboxylic acid ester. The composite catalyst comprises a main catalyst, a cocatalyst and a reducing agent. the main catalyst is at least one of a cobalt salt, cobalt oxide and cobalt hydroxide. The cocatalyst is a nitrogen-containing heterocyclic compound. The reducing agent is a base metal. The method is an atomic reaction type process, does not produce three wastes, and has high conversion rate. It is a green environmental protection process. The composite catalyst used does not contain Co2(CO)8. The raw materials and catalyst used are all cheap and easily available. The composite catalyst can be used repeatedly at a lower cost, and is suitable for industrial applications.

A method of preparing a three-dimensional composite material includes the following steps: preparing polystyrene by soap-free emulsion polymerizing, obtaining polystyrene opal by a vertical deposition method, synthesizing MoP IO (molybdenum phosphide inverse opal), and compounding with quantum points CdS, so as to obtain a novel inorganic composite material, namely cadmium sulfide quantum dot-compounded MoP IO. The preparation method has the advantages that the MoP IO is prepared first, and the MoP IO is of a three-dimensional cyclic pore structure and has the photonic band gap feature, so that the MoP IO has better catalysis effect in light catalysis in comparison with that of common porous material; the MoP IO is compounded with the cadmium sulfide quantum dots, so that the light absorbing ability is enhanced, and the composite material capable of absorbing the visible light is obtained.

A method of preparing hollow molybdate composite microspheres includes steps of: (1) dissolving 1-4 mmol of MCl2 in 20 ml of water to obtain a solution A and dissolving 1-4 mmol. of molybdic acid in 20 ml of water to obtain a solution B, followed by mixing the solution A and the solution B, in which M is Co, Ni, or Cu; (2) dissolving 10-40 mmol of urea in 40 ml of water, adding the mixed solution of step (1) and stirring uniformly; (3) placing the mixed solution of step (2) into a reaction vessel and reacting at 120-160° C. for 6-12 hours; (4) suction filtrating and water washing, followed by drying in a vacuum oven at 40-60° C.; (5) calcination at 350-500° C. for 2-4 hours in a Muffle furnace.

A resolution method of axial chiral enantiomers of lesinurad (2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid) adopts inexpensive and readily available quinoline natural products and derivatives thereof, such as quinine, cinchonine, quinidine or cinconidine as resolving agents to react with lesinurad racemate in an organic solvent to form a salt, and the salt is dissociated by acidification so as to obtain optically pure (R)- or (S)-2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid. The method can give axial chiral enantiomer of lesinurad in R configuration with a chiral purity ee of up to 100% and a total yield of 90% or more. The obtained axial chiral enantiomer of lesinurad in S configuration can reach a chiral purity ee of up to 99.9% and a total yield of 80% or more.

A method for preparing 1,2,4-triazole includes using a fluoroborate aryl diazonium salt, a diazoester derivative and an organic nitrile as reaction substrates, a transition metal salt as a catalyst, and an inorganic base as an additive in a cyclization reaction. The method has the following characteristics: the reaction is economical; the substrate is universal; the post-functionalization is easy; the reaction conditions are mild; the reaction can be performed in air; the catalyst amount used is less; and the post-treatment is simple. Meanwhile, the raw materials, such as the reactants and the catalyst used, are inexpensive and easily available; the reaction composition is reasonable; no ligand is needed; there are less reaction steps; and only one step of reaction is required to obtain a high yield, meeting the requirements and directions of contemporary green chemistry and medicinal chemistry, being suitable for screening highly active 1,2,4-triazole drugs.

The invention discloses an arylpyrrolecarbonitrile compound for insecticidal use, a preparation method and use thereof, an agricultural insecticide and a method for controlling pests. The preparation method comprises the following preparation steps: (1) 2-p-chlorophenyl-4-bromo-5-trifluoromethyl-3-cyanopyrrole, 2-chloro-5-chloromethylthiazole and potassium carbonate are provided as reaction starting materials in a ratio of the amount of substance of 1:1:1.2, and starting materials are put into a three-necked bottle together with DMF; (2) the materials are reacted at 60 to 100° C. for 1 to 4 hours; (3) the reaction is stopped after the completion of the reaction of the starting materials is detected, the materials are cooled to room temperature and filtered by suction to give 4-bromo-2-(4-chlorophenyl)-1-(2-chloro-5-thiazolylmethyl)-5-trifluoromethylpyrrole-3-carbonitrile as a white solid. The compound of the invention has a simple synthesis route, the needed starting materials are cheap and easy to obtain, the product has low production cost and has excellent broad-spectrum insecticidal activity against such plants as rice, cabbage and tomato.