The present invention discloses one kind of composite material of modified micro plant fiber powder and natural rubber and its preparation process and application. The composite material includes natural rubber or latex 100 weight portions, modified micro plant fiber powder 1-60 weight portions, sulfur 0.5-3.3 weight portions, promoter 1.2-4.3 weight portions, antiager 1-3 weight portions and other assistant. The preparation process includes mixing, forming, vulcanizing and other steps. The composite material has high tensile strength, high tearing strength, high ageing resistance, high virus permeation resistance, etc. and may be used widely in making urinary catheter, blood transfusion tube, condom, medical gloves and other products.