94 results about "Tocopheryl phosphate" patented technology

Disclosed herein are a highly purified tocopheryl phosphate and / or a salt thereof (tocopheryl phosphates) wherein a P,P'-bistocopheryl hypophosphate and / or a salt thereof (P,P'-bistocopheryl diphoshates) is contained in a proportion of not higher than 3% by weight; a process for producing a highly purified tocopheryl phosphate and / or a salt thereof, which comprises the steps of reacting a tocopherol with an oxyphosphorus trihalide followed by treating with an acid or basic aqueous solution to thereby form tocopheryl phosphates (i) in which P,P'-bistocopheryl diphoshates (ii) formed as by-products are contained, hydrolyzing the P,P'-bistocopheryl diphoshates (ii) under acid condition, and, optionally, rendering the hydrolyzate neutral or basic under basic condition; and a method of analyzing tocopheryl phosphates, comprising analyzing a sample containing components (i) and (ii) with the use of a high-performance liquid chromatograph column packed with a gel of a polymethacrylate having, bonded thereto, long-chain alkyl groups. None or only an extremely minute amount of P,P'-bistocopheryl diphoshates are contained in the highly purified tocopheryl phosphates, so that the highly purified tocopheryl phosphates exhibit antioxidant and blood circulation promoting effects, have excellent water solubility, are powdery so that the handling thereof is extremely easy, are free from cutaneous irritation and allergenecity and ensure dermal safety. Therefore, the highly purified tocopheryl phosphates are useful as cosmetic ingredients. The amounts of components (i) and (ii) can be simply measured with high accuracy by the above method.

The invention discloses an eye-care composition. The eye-care composition comprises, by weight, 0.1-2 parts of tuberose extract, 0.1-2 parts of aesculus hippocastanum seed extract, 0.1-4 parts of coffee cherry extract, 0.1-2 parts of sodium tocopheryl phosphate and 0.001-0.01 part of acetyl tetrapeptide. The eye-care composition has the advantages that the components of the eye-care composition has a synergic effect on causes of problems such as black eye, eye bags and eye wrinkles affecting eye attractiveness, can stimulate a skin blood circulation system and skin collagen synthesizing again, can allow the eye contour to recover the original shape and color and can allow a user to have even, smooth, bright and young facial appearance. The invention further discloses medicine or eye-care product containing the eye-care composition, and the medicine or eye-care product can aim at different use purposes to improve and reduce the problems such as black eye, eye bags and eye wrinkles affecting eye attractiveness.

Aiming to provide an anti-acne skin care product characterized by good stability, small irritation and applicability to sensitive skin, the invention discloses a skin care product with soothing and anti-acne efficacy. The skin care product comprises an active component and a substrate, and the active component includes the following components by mass percentage: 0.5-2% of gellan gum, 0.3-2.5% of sodium shale oil sulfonate, 0.1-1% of glycerophosphoinositol choline, and 0.5-3% of acne removal agent, wherein the acne removal agent is composed of capryloyl glycine, capryloyl salicylic acid, tocopheryl phosphate, a Chinese trumpet creeper extract, matrine and pyridoxine in a mass ratio of 1:1.5:1:2:1:1. The skin care product belongs to the field of cosmetics.

A dermatological anti-wrinkle agent and an anti-wrinkle cosmetic are stable and satisfactorily effective against wrinkles.The dermatological anti-wrinkle agent comprises a tocopherol phosphate represented by the following formula (1):and / or a salt thereof, wherein R1, R2, and R3 represent a hydrogen atom or a methyl group. The anti-wrinkle cosmetic includes the anti-wrinkle agent.

The invention discloses a quantum skin-clearing and acne-removing facial-beautifying cream comprising the following components: propylene glycol, butanediol, glycerol, betaine, PEG-10 glycerol stearate, cetearyl alcohol, cetearyl glucoside, polydimethylsiloxane, squalane, caprylic / capric triglyceride, tocopherol, laurocapram, an andrographis paniculata extract, a paris polyphylla extract, a puerariae extract, a taraxacum officinale leaf extract, sophocarpidine, capryloyl glycine, capryloyl salicylic acid, tocopherol phosphate, pyridoxine, a centella asiatica flower / leaf / stem extract, a lonicera japonica flower extract, an angelica keiskei leaf / stem extract, a cordyceps militaris extract, a purple magnolia flower extract, a potato pulp extract, polyacrylamide, C13-14 isoparaffin, laureth-7,dipotassium glycyrrhizinate, allantoin, EDTA disodium, methyl hydroxybenzoate, phenoxyethanol, and the balance water. The product not only has good acne-removing effect, but also can desalinate skinacne marks, also makes the skin delicate and smooth, and is suitable for long-term use.

The invention relates to a whitening and freckle removing composition and a preparation method thereof. The whitening and freckle removing composition is prepared from the following components in parts by mass: 1 to 5 parts of polysiphonia urceolata extract, 0.5 to 3 parts of laminaria ochroleuca extract, 3 to 10 parts of radix ginseng extract, 0.5 to 4 parts of paeonia lactiflora root extract, 0.2 to 0.4 part of sodium hyaluronate, 0.1 to 2 parts of sodium tocopherol phosphate and 0.05 to 0.2 part of dipeptide-2. The whitening and freckle removing composition disclosed by the invention has remarkable whitening and freckle removing effects.

A tocopherol phosphoric acid ester represented by a following formula (1) (in the formula, R1, R2, and R3 each independently represents a hydrogen atom or a methyl group,), a pharmacologically-acceptable salt thereof, or a solvate thereof for use in the improvement of skin color.

The present invention disclose a lyophilized pharmaceutical formulation comprising antibacterial agent, daptomycin as active and tocopheryl phosphate hydrolysate mixture with improved reconstitution time for parental administration and to the process of preparation thereof. Daptomycin is a cyclic lipopeptide antibacterial agent derived from the fermentation of Streptomyces roseosporus. The chemical name is N-decanoyi-L-tryptophyl-Dasparaginyl-L-aspartyi-L-threonylglŷ D,-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanines 1-lactone.

The invention discloses an HA (hyaluronic acid)-mediated targeted double-drug-loading cationic liposome coating, which is a cationic liposome coating co-modified by HA (hyaluronic acid), TPGS (tocopheryl phosphate synthase) and polylysine-deoxycholic acid (PLL-DA), and is used for co-delivering PTX (paclitaxel) and SOR (sorafenib) so as to treat multidrug resistance cancers. And the liposome coating adopts a lipid membrane hydration-ultrasonic method to prepare the drug-loaded TPD-CL-PTX / SOR liposome of the HA coating. The multifunctional liposome (HA-TPD-CL-PTX / SOR) can be preferentially gathered at a tumor part through a passive targeting effect and a CD44 mediated active targeting effect after intravenous injection. PTX and SOR are released from tumor cells and have a synergistic anti-tumor effect. Besides, TPGS can further interfere with the mitochondrial function and prevent energy supply of a P-gp efflux pump so as to reduce efflux of PTX or SOR to the maximum extent, so that drugs with high treatment concentration are maintained in cancer cells, multi-drug resistance is effectively reversed, and the method is promising.

The invention relates to an aqueous solution comprising at least one tocopherol phosphate or one of its salts, at least one non-ionic surface-active agent and at least one diol.The invention also relates to a cosmetic composition advantageously obtained using the said aqueous solution.Finally, it relates to a care method using the said composition.

The invention discloses an acne-removing original solution and a preparation method thereof, wherein the acne-removing original solution includes the following raw materials by weight: 8-13% of water,2-4% of butanediol, 2-5% of octyl glycine, 2.5-3.5% of tocopherol phosphate, 5-8% of a campsis grandiflora extract, 5-8% of a radix sophorae extract, 5-8% of an amur corktree bark extract, 2-5% of anazadirachta indica leaf extract, 5-10% of a centella root extract, 2-5% of a white willow bark extract, 10-15% of a wild soybean protein, 10-15% of an aloe vera flower extract, 5-8% of p-hydroxyacetophenone, 2-4% of 1,2-hexanediol, and 2-5% of sodium hyaluronate. The wild soybean protein and the aloe vera flower extract in the prepared acne-removing original solution cooperate with each other andcan effectively supplement nutrition on cells of facial acne marks, so as to facilitate the elimination of the acne marks.

The invention relates to a preparation method of a biological air freshener for removing methanal. The air freshener is prepared by mixing oligose, water-soluble olive oil, azelaic acid, oat polypeptide, polyquaternium, bisabolol, walnut oil, green tea essence, jojoba oil, a probiotic group, tocopherol phosphate, octanoylsalicylic acid, pyridoxine, black currant oil, fatty alcohol ether sulfate, ferment, acetic acid, aromatic and water. The air freshener is specialized in removing harmful gas such as the methanal, benzene, methylbenzene, dimethylbenzene and ammonia and various peculiar smells generated in an automobile, rapidly eliminates peculiar smell molecules, improves the quality of air, purifies the air, removes the peculiar smells, eliminates bacteria, and keeps the air persistently fresh.

Compositions and methods for treating skin redness. According to an embodiment, the invention is a topical skin care composition having a dermatologically acceptable vehicle, such as, water and a plurality of ingredients dissolved in the vehicle. The ingredients include: a blend of natural oils; a plurality of vitamins; and 0.1 - 1 wt% salicyloyl phytosphingosine. The composition is unsuitable forapplication on the eyelids or eye area. The blend of natural oils includes: aloe barbadensis leaf juice extract; cocos nucifera (coconut oil); hydrolyzed glycosaminoglycans; and caprylic / capric triglycerides. The plurality of vitamins is selected from a group consisting of vitamin C, vitamin E, salts / derivatives of vitamin C and vitamin E, and mixtures thereof. In one aspect, the plurality of vitamins includes: sodium ascorbyl phosphate; disodium lauriminodipropionate tocopheryl phosphate; and jojoba oil.

The invention discloses a solvent for preparing an active substance facial mask. The solvent is prepared from the following components in parts by weight: 80-100 parts of water for injection, 0.01-0.05 parts of alpha-sodium tocopheryl phosphate salt, 0.01-0.05 parts of isoflavone, 0.01-1 part of sodium chloride, 0.01-10 parts of glycerin, 0.01-5 parts of mannitol, 0.01-5 parts of trehalose and 0.01-1 part of Tween 80. The invention further provides a preparation method and an application of the solvent. Polypeptide and the mask are separately packaged and stored, and polypeptide is preserved at a low temperature, so that activity of polypeptide can be maintained for a long time; a common mask is preserved at the room temperature, and during using, active substance polypeptide is dissolvedby a solvent and added to the common mask to be combined into the polypeptide mask for use; the facial mask can obviously lighten spots, improve immunity, promote generation of collagen, generation ofmicrovessels and tissue regeneration, and make the skin more elastic.

The invention relates to an aqueous solution comprising at least one tocopherol phosphate or one of its salts, at least one non-ionic surface-active agent and at least one diol. The invention also relates to a cosmetic composition advantageously obtained using the said aqueous solution. Finally, it relates to a care method using the said composition.

A dermatological anti-wrinkle agent and an anti-wrinkle cosmetic are stable and satisfactorily effective against wrinkles. The dermatological anti-wrinkle agent includes a tocopherol phosphate represented by the following formula (1):and / or a salt thereof, wherein R1, R2, and R3 represent a hydrogen atom or a methyl group. The anti-wrinkle cosmetic includes the anti-wrinkle agent.

The invention discloses a skincare composition for preventing skin from ageing and a preparation method of the skincare composition. The composition consists of the following components in percentageby weight: 50-65% of water, 20-40% of glycerine, 0.1-0.2% of carbomer, 0.1-0.2% of triethanolamine, 0.1-0.3% of tocopheryl phosphate, 1-10% of an olive leaf extract, 0.1-0.5% of a radix rhodiolae extract, 0.1-0.3% of phenoxyethanol, 0.01-0.1% of chlorphenesin, 0.01-0.3% of PEG-40 hydrogenated castor oil, 0.1-0.3% of avocado pear oil, 0.1-0.5% of apricot stone oil and 0.01-0.1% of essence. Raw materials are sequentially taken, and after the skincare composition is prepared, discharging is performed. The skincare composition can strengthen the immunity capacity of cells, whiten and moisturize skin, repair the skin, enable the skin to be regenerated, enable fine wrinkles to be not obvious, enable the skin to be delicate and smooth, dispel freckles, resist wrinkles and prevent the skin from ageing.

The indoor enzyme air freshener technical scheme of the present invention is realized in this way, and it is made of oligomonosaccharide, water-soluble olive oil, azelaic acid, oat polypeptide, polyquaternium salt, bisabolol, rice bran oil, green tea essence, jojoba Oil, Probiotics, Tocopheryl Phosphate, Caprylyl Salicylic Acid, Azelaic Acid, Pyridoxine, Cathone 2, Niacinamide, Pectinase, Candida utilis, Rosa Rose, Water .

The invention relates to a preparation method of a toilet enzyme sterilizing agent. According to the technical scheme, the toilet enzyme sterilizing agent is prepared by mixing mono-oligosaccharide, water-soluble olive oil, azelaic acid, L-sodium ascorbate, trichoderma longibrachiatum, bifidobacterium adolescentis, pine-seed oil, green tea essence, AES, probiotics, tocopherol phosphate, capryloyl salicylic acid, azelaic acid, pyridoxine, wheat-germ oil, alkyl polysaccharide 0810, enzyme, acetic acid, osmanthus flavor and water.

The invention discloses a preparation method of an enzyme cleaning agent for bathtubs. The technical scheme includes that the enzyme cleaning agent is prepared by mixing niacinamide, pectinase, candida utilis, oat polypeptide, polyquaternium, bisabolol, sunflower seed oil, green tea essence, AES, probiotics, tocopheryl phosphate, capryloyl salicylic acid, rhododendron extract, pyridoxine, VE oil, sodium alcohol ether sulfate, enzymes, acetic acid, jasmine flavor and water.

The invention relates to a skin care composition with anti-allergy and anti-corrosion effects and a preparation method thereof. The composition comprises the following components in percentage by mass: 10%-40% of a functional active matter, 20%-30% of an isoprene glycol-propylene glycol mixed solution, 2%-12% of phospholipid, 0.2%-8% of cholesterol, 0.2%-6% of sodium tocopheryl phosphate and 2%-15% of vegetable oil, with the balance being deionized water, wherein the functional active matter is composed of sophocarpidine, ligustilide, gentiopicroside and wasabia japonica root extract accordingto a mass ratio of (3-5): (2-3): (1-3): (3-6); the isoprene glycol-propylene glycol mixed solution is composed of isoprene glycol and propylene glycol according to a mass ratio of (2-3): (5-7); and the vegetable oil is one or a mixture of more than one selected from linseed oil, basil oil and salvia hispanica seed oil. The composition has good effects of resisting allergy and removing couperose skin after inflammation, has a certain preservative effect, and also has the advantages of high transdermal absorption rate and easiness in absorption by skin.

The invention relates to a preparation method of a pipeline dredging agent. The pipeline dredging agent is prepared by mixing a radix stephaniae tetrandrae extract, water-soluble olive oil, azelaic acid, oat polypeptide, polyquaternary salt, bisabolol, millet bran oil, green tea essence, AES, probiotic flora, tocopheryl phosphate, octanoylsalicylic acid, azelaic acid, pyridoxine, Kathon 2, sodium alcohol ether sulphate, ferment, acetic acid, spice and water. The pipeline dredging agent is good in deodorization effect and safe in use, and can be used for removing odor such as fecal odor of ammonia gas, hydrogen sulfide and nicotine generated by cigarettes as well as methylindole serving as main sources and dredging blockage caused by all organic substances such as oil, hairs, vegetable residues and paper cotton fibers in pipelines of a kitchen and a bathroom; the pipeline dredging agent has the efficacy of removing pipeline stench, killing bacteria and parasites in the pipelines and the like, and helps a family to clean a hygienic dead angle of the last place.

The invention discloses a preparation method of an enzyme cleanser for air conditioners. According to the technical scheme, the enzyme cleanser for air conditioners is prepared by mixing D-biotin, lonely humicola, streptococcus thermophilus, oat polypeptide, quaternary ammonium salt, bisabolol, avocado oil, green tea essence, AES, probiotics, tocopherol phosphate, capryloyl salicylic acid, azelaic acid, pyridoxine, Kathon 2, fatty alcohol ether sulfate, enzymes, acetic acid, rose flavor, and water.

The invention relates to a preparation method of a cleaning agent for laboratory ware. The cleaning agent is prepared by mixing oligose, water-soluble olive oil, azelaic acid, fat-soluble coenzyme Q10, polyquaternium, bisabolol, seabuckthorn seed oil, green tea essence, AES (acrylonitrile ethylene-propylene-diene monomer styrene), a probiotic group, tocopherol phosphate, octanoylsalicylic acid, pyridoxine, okra seed oil, alkyl polysaccharide 0810, ferment, acetic acid, aromatic and water. The cleaning agent is used for laboratory vessel dirt, particularly attached metal ion dirt, is good in elution effect, short in washing time, simple in washing process and convenient to use, causes no pollution to the environment, and has no stimulation to human skin.

The invention discloses a preparation method of an enzyme cleaning agent for bathtubs. The technical scheme includes that the enzyme cleaning agent is prepared by mixing D-biotin, humicola insolens, streptococcus thermophilus, oat polypeptide, polyquaternium, bisabolol, sunflower seed oil, green tea essence, AES, probiotics, tocopheryl phosphate, capryloyl salicylic acid, rhododendron extract, pyridoxine, VE oil, sodium alcohol ether sulfate, enzymes, acetic acid, jasmine flavor and water.

The invention relates to a preparation method of an enzyme detergent for laboratory ware. According to the technical scheme, the enzyme detergent for laboratory ware is prepared by mixing thiamine mononitrate, protease, bifidobacterium infantis, lipid-soluble coenzyme Q10, polyquaternium, bisabolol, seabuckthorn seed oil, green tea essence, AES, probiotics, tocopheryl phosphate, capryloyl salicylic acid, azelaic acid, pyridoxine, okra-seed oil, alkyl polyglucosides(APG0810), enzyme, acetic acid, sweet osmanthus flavor and water.

The invention discloses a preparation method of an indoor enzyme air freshener. According to the technical scheme, the indoor enzyme air freshener is prepared by mixing mono-oligosaccharide, water-soluble olive oil, azelaic acid, oat polypeptide, polyquaternium, bisabolol, millet bran oil, green tea essence, jojoba oil, probiotics, tocopheryl phosphate, capryloyl salicylic acid, azelaic acid, pyridoxine, Kathon 2, L-sodium ascorbate, keratinase, bifidobacterium longum, rose flavor and water.

The invention discloses a preparation method of an enzyme cleanser for air conditioners. According to the technical scheme, the enzyme cleanser for air conditioners is prepared by mixing thiamine mononitrate, protease, bifidobacterium infantis, oat polypeptide, quaternary ammonium salt, bisabolol, avocado oil, green tea essence, AES, probiotics, tocopherol phosphate, capryloyl salicylic acid, azelaic acid, pyridoxine, Kathon 2, fatty alcohol ether sulfate, enzymes, acetic acid, rose flavor, and water.