30 results about "Superior vena caval" patented technology

Methods of locating a tip of a central venous catheter (“CVC”) relative to the superior vena cava, sino-atrial node, right atrium, and / or right ventricle using electrocardiogram data. The CVC includes at least one electrode. In particular embodiments, the CVC includes two or three pairs of electrodes. Further, depending upon the embodiment implemented, one or more electrodes may be attached to the patient's skin. The voltage across the electrodes is used to generate a P wave. A reference deflection value is determined for the P wave detected when the tip is within the proximal superior vena cava. Then, the tip is advanced and a new deflection value determined. A ratio of the new and reference deflection values is used to determine a tip location. The ratio may be used to instruct a user to advance or withdraw the tip.

Apparatus and methods for cooling selected regions within a body are described herein. An implantable cooling system is used to cool regions of the brain, spinal cord, fibrous nerve bodies, e.g., vagus nerve, etc. down to about 30° C. to diminish nerve impulses which control seizures or chronic pain. The system includes an implantable unit containing a pumping mechanism and / or various control electronics. It also has a heat exchanger attachable to a tubular body organ, such as the superior vena cava or the inferior vena cava, through which the heat is effectively dissipated. Also included is a heat pump such as a Peltier junction configured to be placed into contact with the region of tissue to be cooled. The heated portion of the Peltier junction is cooled by a liquid heat transfer medium which absorbs the heat from the junction and dissipates it into the tubular body organ.

A method of surgical perforation via the delivery of electrical, radiant or thermal energy comprising the steps of: introducing an apparatus comprising an energy delivery device into a patient's heart via the patient's superior vena cava; positioning the energy delivery device at a first location adjacent material to be perforated; and perforating the material by delivering energy via the energy delivery device; wherein the energy is selected from the group consisting of electrical energy, radiant energy and thermal energy.

Disclosed is a method for the diagnosis of conductor anomalies, such as an insulation failure resulting in a short circuit, in an implantable medical device, such as an implantable cardioverter defibrillator (ICD). Upon determining if a specific defibrillation pathway is shorted, the method excludes the one electrode from the defibrillation circuit, delivering defibrillation current only between functioning defibrillation electrodes. Protection can be provided against a short in the right-ventricular coil-CAN defibrillation pathway of a pectoral, transvenous ICD with a dual-coil defibrillation lead. If a short caused by an in-pocket abrasion is present, the CAN is excluded from the defibrillation circuit, delivering defibrillation current only between the right-ventricular and superior vena cava defibrillation coils. Determination that the defibrillation pathway is shorted may be made by conventional low current measurements or delivery of high current extremely short test pulses.

Apparatuses and methods for the perforation of heart tissue of a patient when an inferior approach to the heart is contraindicated are disclosed. The method includes using a superior approach to introduce the apparatus, positioning the apparatus at a tissue location and delivering a controlled amount of non-mechanical energy to the tissue to create a perforation. For example, a method of surgical perforation via the delivery of electrical, radiant or thermal energy may include: introducing an apparatus comprising an energy delivery device into a patient's heart via the patient's superior vena cava; positioning the energy delivery device at a first location adjacent material to be perforated; and perforating the material by delivering energy via the energy delivery device; wherein the energy is selected from the group consisting of electrical energy, radiant energy and thermal energy.

Systems and methods are provided wherein intracardiac electrogram (IEGM) signals are used to determine a set of preliminary optimized atrioventricular (AV / PV) and interventricular (VV) pacing delays. In one example, the preliminary optimized AV / VV pacing delays are used as a starting point for further optimization based on impedance signals such as impedance signals detected between a superior vena cava (SVC) coil electrode and a device housing electrode, which are influenced by changes in stroke volume within the patient. Ventricular pacing is thereafter delivered using the AV / VV pacing delays optimized via impedance. In another example, parameters derived from IEGM signals are used to limit the scope of an impedance-based optimization search to reduce the number of pacing tests needed during impedance-based optimization. Biventricular and multi-site left ventricular (MSLV) examples are described.

The invention relates to a transcatheter heart valve replacement (A61F2 / 2412), and in particular Compression Capable Annular Frames for a side delivered transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

The invention relates to the technical field of cardiac rhythm medical equipments, and discloses a cardiac implantation device and a pacing system. In the invention, the cardiac implantation device comprises a first connector of which one end is used for being connected with a pacemaker and N support rods, wherein the proximal end of each support rod is connected with the other end of the first connector; a positioning part is arranged on each support rod for fixing while implanting, the distal end of each support rod is in a free state and can be expanded or drawn; the invention further discloses the pacing system comprising the implantation device and the pacemaker. By adopting the cardiac implantation device and the pacing system, the wire-less pacemaker can be implanted into the superior vena cava of a human body to sense and pace atriums, and the wire-less pacemaker is easier to recover and the success rate of chronically removing the lead-free pacemaker is improved. Therefore, the application of the wire-less pacemaker is facilitated and the use experience of patients is improved.

Apparatus and methods for cooling selected regions within a body are described herein. An implantable cooling system is used to cool regions of the brain, spinal cord, fibrous nerve bodies, e.g., vagus nerve, etc. down to about 30° C. to diminish nerve impulses which control seizures or chronic pain. The system includes an implantable unit containing a pumping mechanism and / or various control electronics. It also has a heat exchanger attachable to a tubular body organ, such as the superior vena cava or the inferior vena cava, through which the heat is effectively dissipated. Also included is a heat pump such as a Peltier junction configured to be placed into contact with the region of tissue to be cooled. The heated portion of the Peltier junction is cooled by a liquid heat transfer medium which absorbs the heat from the junction and dissipates it into the tubular body organ.

The invention provides a zolmitriptan sublingual tablet, which is characterized in that it contains the main drug zolmitriptan, a disintegrating agent and a filler. In every 1000 sublingual tablets, the content of zolmitriptan is 1 -50g, the content of disintegrating agent is 2-20g, the content of filler is 40-200g; it also contains 0-20g of corrective agent, 10-60g of binder and 0.5-5g of lubricant. The present invention utilizes the characteristics of non-keratinized sublingual mucosa, rich capillaries, and fast blood flow, aiming at the absorption of zolmitriptan ordinary tablets through the gastrointestinal tract, slow onset of action, first-pass effect, and low bioavailability. The deficiencies of advanced prior art, zolmitriptan is made into sublingual tablet, can make it absorb through sublingual mucosa, directly enter blood circulation through jugular vein and superior vena cava, take effect rapidly; Avoid oral administration The first-pass effect improves bioavailability and ensures curative effect. Moreover, water is not needed when taking the medicine, and it is placed under the tongue to contain it, so it is convenient to take and has a good taste. With the characteristics of rapid onset of action, convenient administration and high bioavailability, it can provide patients with a new treatment option and fill the gap in the market.

A device for the real-time in vivo detection of a number of conditions within the patient, including CTCs, circulating nucleic acids, other circulating elements, blood pressure, heart rate data, pulse oxygen concentration, serum electrolyte concentrations, blood glucose, and pH, the device having an implanted subcutaneous access port in the chest region and a catheter having a terminus in the superior vena cava, the device having microelectronic circuitry with a rechargeable energy source encased in a titanium shell, an NIR laser sealed in the titanium-enclosed circuitry platform, and NIR-specific optical fibers (nir-FO) for transmitting the NIR photons to the end of the catheter tube in the superior vena cava. Scattered NIR photons are collected through the end of a second nir-FO bundle and transmitted back to the detector and microprocessor on the portal platform.

The invention provides an auxiliary pump blood catheter pump, which relates to the technical field of medical apparatus and instruments, and comprises a fixed support assembly, a fluid tube and an axial flow impeller, a blood inlet and a blood outlet are formed in the fluid pipe, the fixed supporting assembly is connected with the pipe wall of the fluid pipe, and the fixed supporting assembly has a reversible unfolding posture and a reversible storage posture; and the product can be implanted into a blood transfusion organ through a catheter, large surgical operations such as thoracotomy are not needed, trauma is small, and recovery is fast. When the device is applied to the aorta connected with the left ventricle, the blood inlet of the fluid tube is communicated with the left ventricle, and the device is used for improving the hemodynamic performance in the heart, increasing the cardiac output or assisting a high-risk cardiac surgery; when applied to the descending aorta, the product can improve the kidney perfusion pressure in the descending aorta and is used for preventing renal failure caused by acute heart failure; when applied to the interiors of superior vena cava, inferior vena cava or pulmonary arteries and the like, the pressure in blood vessels can be increased, and blood perfusion of all blood transfusion organs is improved.

The invention relates to a flunitrazepam sublingual tablet preparation and a preparation method thereof. Every 1000 sublingual tablets contain 1-3g of flunitrazepam, 5-10g of polyvinylpyrrolidone K30, 30-50g of polyethylene glycol 6000, 30-60g of sorbitol, 2-10g of labrasol, and 0.5-2g of magnesium stearate. According to the invention, by utilizing the characteristics that sublingual mucosa is non-cornified, capillaries are abundant, and blood flows fast, and directed at the disadvantages that drug administration of flunitrazepam through gastrointestinal tract needs time and intramuscular injection is relatively troublesome, flunitrazepam is prepared into a sublingual tablet that can be absorbed through sublingual mucosa and directly enter blood circulation through jugular vein and superior vena cava. The sublingual tablet takes effect fast and guarantees the curative effect, does not need water during taking, is for sublingual administration, is convenient to take orally, and has good taste.

The invention relates to determining a representation of cardiac output in a patient. Provided are a method and a system for monitoring a cardiac output using a single device inserted into a Central Venous Catheter (CVC) or Peripheral Inserted Central Catheters (PICC) line. In an embodiment, the device contains an elongated body that fits the lumen of a Central Venous Cava or Peripheral Inserted Central Catheters line and has an ultrasound transducer at the tip. By operating the device such that the velocity in both the Superior Vena Cava and Inferior Vena Cava can be sampled continuously the CO is monitored.

The invention belongs to the field of medical devices, relates to a puncture instrument for cardiac surgery and especially relates to a puncture instrument used in left ventricle endocardium pacing. The instrument comprises a puncture steel needle, a puncture sheath tube and a steel needle introducer; the puncture steel needle is guided by the steel needle introducer to the puncture sheath tube; the tail end of the puncture steel needle is fixedly connected with a puncture head; the puncture sheath tube is overall in a spatial conformation of S-shape and the tail end is shaped as a hanging basket; the steel needle introducer is overall cylindrical and hollow. Application results show that the puncture instrument for cardiac surgery can accurately position interatrial septum; by means of the puncture instrument, surgical procedures are simplified and safe; the puncture instrument can be used in left ventricle endocardium pacing and can be directly puncture the interatrial septum from superior vena cava.

The invention relates to determining a representation of cardiac output in a patient. Provided are a method and a system for monitoring a cardiac output using a single device inserted into a Central Venous Catheter (CVC) or Peripheral Inserted Central Catheters (PICC) line. In an embodiment, the device contains an elongated body that fits the lumen of a Central Venous Cava or Peripheral Inserted Central Catheters line and has an ultrasound transducer at the tip. By operating the device such that the velocity in both the Superior Vena Cava and Inferior Vena Cava can be sampled continuously theCO is monitored.

The invention relates to a transcatheter heart valve replacement (A61F2 / 2412), and in particular Compression Capable Annular Frames for a side delivered transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

The invention provides an implantable cardiac resynchronization pace-making defibrillator of a His-Purkinje system. The implantable cardiac resynchronization pace-making defibrillator has two models FD-F and FD-1. The FD-F is provided with an F mark, a His-Purkinje F IS-1 jack, right ventricular and right atrium IS-1 jacks, two suture fixing holes, superior vena cava and right ventricular DF-1 jacks, a left ventricular IS-1 jack, six electrodes, a communication coil, a pace-making circuit, a battery, a shell, a capacitor, a sealing groove and the like. The F mark is convenient to identify beside the His-Purkinje F IS-1 jack. Compared with the model FD-F, the model FD-1 has the advantages that one jack and one electrode are omitted, and the remaining structure and the connection mode are the same as those of the model FD-F. The defibrillator can adjust the pace-making sensing function of the F jack, is used for His-Purkinje mediated cardiac resynchronization pace-making defibrillation,can be specially used for His-Purkinje resynchronization pace-making defibrillation, and can also be used for wide QRS and left ventricle electrodes to jointly participate in resynchronization pace-making defibrillation treatment. The defibrillator is suitable for different implantation connection requirements, and related complications caused by excessive electrodes in a bag are reduced.

Blood flow affecting implant and implantation thereof in superior vena cava, optionally including disintegration of endothelium layer and inducing tissue ingrowth within implant. Implant includes elongated body with optional tubular inner layer forming orifice, shapeable to final orifice diameter for restricting blood flowing therethrough to chosen average flow rate; and / or tubular outer layer provided coaxially around inner layer. Outer layer is formed of second material provided in elastically deformable state for facilitating elastic radial self¬expanding from collapsed diameter up to relaxed maximal expanded diameter greater than diameter of inner wall portion of superior vena cava. Inner layer is formed of first material, in plastically or elastically deformable state.

A zero flow responsive heart stimulator contains a zero flow sensors, which generate signals at the moment of the termination of blood inflow in the right atrium and the right ventricle, sensing this the most precisely in the places, where the sinoatrial node and atrioventricular node reside, for the right atrium and the right ventricle, respectively. The stimulator is based on our discovery, that the two nodes are the same sensors in the biological systems, based on the fact that until the filling of the said two chambers continues, the venous blood flow sucks on Bernoulli's principle the Ca and Na cations from the two nodes interstices, preventing the inward currant in their cells, thus delaying the completion of the 0-phase of their depolarization and the action potential, until the blood flow stops. Our discovery proves that the alternating flow / no flow of the blood in the orifice of superior vena cava and the entrance of the right ventricle is the real pacemaker that fires the both nodes, but not the inverse, as generally assumed, approximating the natural pacemaker to a clock mechanism. This, together with the discovered by us arteriovenous, arteriolymphatic and capillary pumps, closes the loop of the autonomous automatic functioning of the cardiovascular system, even completely denervated and in the absence of muscle contractions. It is the first devise, which activates the atrial and the ventricular contractions in a function of the zero-flow of the filling them venous blood, which is the exact imitation of the sinoatrial and atrioventricular firing.

A medical device for treating cardiac rhythm disorders, and a cardiac implantation device and a pacing system. The cardiac implantation device includes: a first connecting member having an end configured to be coupled to a pacemaker; and N support struts, each of the N support struts having a proximal end coupled to the other end of the first connecting member. The support struts are provided thereon with anchor(s) configured to secure during implantation. Distal ends of the support struts are free and are able to radiate outwardly or converge inwardly. The pacing system includes the implantation device and a pacemaker. A leadless pacemaker can be implanted into the superior vena cava in order to achieve atrial sensing and pacing. Moreover, the leadless pacemaker can be more easily retrieved after long-term implantation at a high success rate, promoting the application of leadless pacemakers and enhancing patients' use experience.

A long-term internal temperature measurement device includes a silastic, tunneled right-atrial catheter having a distal end adapted to be directed into the superior vena cava of a patient to reside within one of the superior vena cava and the right atrium of the patient's heart, an outer end extending outside of the patient and a cuff positionable beneath the skin of the patient for generally preventing bacterial growth up the catheter. A thermistor device is mounted within the catheter, specifically within the distal end of the catheter, the thermistor device operative to measure the temperature of blood flowing through the patient's right atrium or superior vena cava. Finally, an electronic display device is in information transmission connection with the thermistor device and further is operative to display the internal temperature of the patient as measured by the thermistor device within the patient's right atrium or superior vena cava.

A self-expandable stent has a dry valve made of bovine pericardium arranged at a proximal end thereof, a skirt surrounding the dry valve at the proximal end of the stent and made of one of bovine pericardium and polyester. The dry valve is configured to be rehydrated when placed in contact with a solution, and the stent includes eyelets arranged at the proximal end of the stent for fixing the stent at a point of interest, with the point of interest being one of the vena cava superior and the vena cava inferior.

The invention provides a method for controlling enhanced nuclear magnetic resonance imaging. The method comprises the following steps: S1, performing pre-scanning to obtain a plurality of tomography images of a coronal plane; S2, respectively finding a superior vena cava and an aorta in the tomography images, wherein the superior vena cava is in a first tomography image and the aorta is in a second tomography image; S3, connecting any point of the superior vena cava in the first tomography image to any point of the aorta in the second tomography image to obtain an oblique tomography line; S4,drawing a section perpendicular to the shaft-shaped surface through the oblique tomography line, and taking the section as a reference surface; S5, performing scanning imaging on the reference surface, injecting a contrast agent, and monitoring the movement track of the contrast agent in the superior vena cava and aorta vessels in the reference surface; S6, when it is monitored that the contrast agent enters the aorta, performing voice prompt; and S7, scanning an area to be imaged to obtain an image of the required part. The method can solve the technical problem that enhancement of nuclear magnetic resonance imaging is affected due to the fact that a patient does not hold breath in time after hearing the voice prompt.

The invention discloses a gingko general flavone sublingual tablet and a preparation method thereof.The sublingual tablet is prepared from, by weight, 1-260 parts of gingko general flavone, 2-25 parts of disintegrating agent and 35-245 parts of filler.Gingko general flavone is prepared from, by weight, 35-50% of quercetin, 6-16% of kaempferide and 15-25% of isorhamnetin.The gingko general flavone sublingual tablet is prepared by organically combining disintegrating agent with filler, and the tablet is put under a tongue when taken and can be rapidly disintegrated and absorbed by sublingual mucosal and directly enter blood circulation through jugular veins and superior vena cava to rapidly act so as to rapidly relieve migraine symptoms.Meanwhile, the tablet is particularly suitable for the aged and other patients having difficulty in swallowing and patients having difficulty in taking water in special environments such as battlefields, outdoor environments and tourist environments.

The present invention provides an improved structure of automobile shock absorber, which belongs to Shock Absorber technology. It solved the existing technologies that are more complex structure, the noise, vibration effect is not satisfactory, shorter service life deficiencies.Shock absorber, including one outside cylinder, a cylinde sets outer tube, the cylinder barrel and the piston is connected to the piston rod and the cylinder piston will be separated into upper and lower chamber cavity, the outer end rod extending out cylinder, described at the bottom of a cylinder and cylinder connected to the inferior vena cava through the tubing, Qualcomm, which covers the extension of the pipeline through the cylinder to the cavity, Cylinder the inferior vena cava and the superior vena cava link. Improve the structure of the automobile shock absorber design of the structure is not only reasonable regulation of stability, and work noise, the advantages of long life, and can be easily carriedout to improve the existing technical.

The invention discloses a superior vena cava cannula dilation guide wire, which comprises an L-shaped superior vena cava cannula, wherein an opening is formed in one end of the superior vena cava cannula; a guide wire body is arranged in the superior vena cava cannula; a dilation inflated balloon is arranged at the front end of the guide wire body; and the dilation inflated balloon is connected to a connecting tube. The dilation guide wire provided by the invention has the advantages of being simple in structure and skillful in design; moreover, the opening is blocked as the dilation inflated balloon, which gets inflated, is expanded; the guide wire body takes an effect of guiding; the dilation inflated balloon, which is provided with a conical head, can facilitate deep extension, so that bleeding and injury are relieved; aspirating is implemented and the guide wire body is withdrawn as the cannula is successfully implanted; and the dilation guide wire has the advantages of being convenient to operate and the like.

The invention discloses an autonomous PICC functional exerciser, and belongs to the technical field of medical auxiliary instruments. The autonomous PICC functional exerciser comprises an arm sleeve which is of a double-layer structure, wherein an air chamber is formed between the double-layer structure; an inflation device which is communicated with the air chamber; a deflation valve which is arranged on the arm sleeve and communicated with the air chamber; and a controller which is connected with the inflation device and the deflation valve and can control a pressure threshold value and inflating and deflating time. The autonomous PICC function exerciser can also be used by a patient lacking autonomous exercise ability, and medical workers can set exercise time and pressure according to individualized requirements, so that exercise is more scientific and effective. According to the exerciser, the mode of segmental gradual autonomous inflation and deflation is adopted, blood is sequentially pressed into the forearm from the hand, then pressed into the upper arm and finally converged into the superior vena cava through the pressure of air in the air chamber, and the effects of promoting blood backflow of the upper limbs, reducing thrombosis and preventing PICC complications are achieved.

The present invention relates to the technical field of auxiliary treatment apparatus after Fontan operation, in particular to a new type of auxiliary device for treating Fontan circulatory failure, including a balloon placed at the confluence of pulmonary artery, superior vena cava and inferior vena cava after Fontan operation and the two ends of the balloon are respectively located in the superior vena cava and the inferior vena cava; as the balloon is inflated and deflated, the blood in the superior vena cava and inferior vena cava is extruded into the pulmonary artery. Through the above method, the balloon is placed at the intersection of the pulmonary artery, the superior vena cava and the inferior vena cava, and the balloon is inflated and contracted by inflation and deflation of the balloon, and then the superior vena cava and the inferior vena cava The blood in the lung is squeezed into the pulmonary artery. The valve coupled with the balloon opens and closes synchronously, preventing the blood from flowing backward into the superior and inferior vena cava. As a result, the pulsating blood enters the pulmonary artery and plays the role of part of the right ventricle, thereby treating patients with Fontan circulation failure and providing powerful conditions for later heart transplantation.