43 results about "Soft tissue sample" patented technology

A handheld biopsy device is provided for the collection of soft tissue samples from a surgical patient. In a preferred embodiment, the biopsy device comprises a handpiece, a fluid collection system, and a power transmission source. The handpiece is configured for grasping by a single hand, and being independently manipulatable by hand for movement of the instrument toward and away from the patient. An elongated piercer extends from the distal end of the handpiece. The piercer has a sharpened distal end for entering the tissue and a port located proximal to the sharpened distal end for receiving a portion of tissue mass. An elongated cutter is disposed coaxially relative to a piercer lumen of the piercer. A distal blade of the cutter slides distally past the port of the piercer to severe the tissue portion drawn into the port by vacuum. The cutter is retracted to a most proximal position for removal of the tissue portion from a cutter lumen of the cutter. The handpiece further comprises a holster for detachably connecting a cutter rotation transmission and a cutter axial transmission to the power transmission source.

A biopsy probe for the collection of at least one soft tissue sample from a surgical patient. The biopsy probe has a frame and an elongated piercing element having a proximal end attached to the distal end of the frame and a sharpened distal end for piercing tissue. The piercing element has a lumen extending at least partially therethrough. The probe also includes an elongated cutter disposed coaxially and slidably within the lumen of the piercing element. The cutter has a distal end for cutting a tissue sample, a proximal end and a body connecting the distal and proximal ends, wherein at least a portion of the body comprises a flexible member.

The present invention is a process for preparing soft tissue such as tendons, ligaments, cartilage, fascia, dermis, human valves and human veins for implant in a human and removes cellular components and forms an decellular matrix having as major components collagens and elastins while sterilizing the tissue. The process comprises the following steps:(1) isolating from a suitable donor a desired soft tissue sample of the biological material;(2) processing and decellularizing the soft tissue including inspection for visual defects, trimming and soaking the tissue in a detergent depending on whether the tissue is fascia or dermis and rinsing same with sterile water;(3) sterilizing the soft tissue in a vacuum and soaking the tissue in an antibiotic composition or peracetic acid depending on whether the soft tissue is fascia or dermis and rinsing same;(4) processing the tissue by cutting the tissue to size and perforating the tissue; and(5) dipping the tissue in 70% ethanol and packaging the tissue.

A handheld biopsy device is provided for the collection of soft tissue samples from a surgical patient. At least one electrode is provided, such as between a handle and the knife tip of the biopsy device. The electrodes can be provided on a sleeve. The sleeve with electrodes can be releasably supported on the biopsy device.

A handheld biopsy device is provided for the collection of soft tissue samples from a surgical patient. In a preferred embodiment, the biopsy device comprises a handpiece, a fluid collection system, and a power transmission source. The handpiece is configured for grasping by a single hand, and being independentyl manipulatable by hand for movement of the instrument toward and away from the patient. An elongated piercer extends from the distal end of the handpiece. The piercer has a sharpened distal end for entering the tissue and a port located proximal to the sharpened distal end for receiving a portion of tissue mass. An elongated cutter is disposed coaxially relative to a piercer lumen of the piercer. A distal blade of the cutter slides distally past the port of the piercer to severe the tissue portion drawn into the port by vacuum. The cutter is retracted to a most proximal position for removal of the tissue portion from a cutter lumen of the cutter. The handpiece further comprises a holster for detachably connecting a cutter rotational transmission and a cutter axial transmission to the power transmission source.

The invention discloses a method for detecting density distribution of micro-plastics in soft tissues of marine organisms, and belongs to the field of micro-plastics in fish or bivalve organism samples. The method for detecting the density distribution of the micro-plastics in the soft tissues of the marine organisms comprises the following steps of selecting the fish or bivalve organisms with similar individuals, washing the fish or bivalve organisms with pure water to prepare digestive tract or soft tissue samples, and recording the weights; preparing a digestion solution for digesting the prepared samples, and obtaining a mixed digestion solution; adding NaCl into the mixed solution to carry out density flotation; and carrying out microscopic examination on particles subjected to flotation, selecting the suspected particles to be subjected to analysis of a microscopic-Fourier spectrometer and the like, performing counting after the particles are identified as the micro-plastics, andperforming calculation to obtain the density distribution of the micro-plastics. According to the method, the micro-plastics in the digestive tracts or the soft tissues of the marine organisms can beaccurately quantified, thereby providing basic data for the pollution condition of the micro-plastics in an area.

The invention discloses an X-ray imaging system and method based on grating phase contrast and photon counting. X-rays become coherent X-rays after being shaped through a light source grating; the coherent X-rays containing phase changes after penetrating through samples form beam-split X-rays through a phase grating; the phase changes of the X-rays are converted into light intensity changes after the X-rays pass an analyzing grating; a photon counting detector is used for recording phase contrast information of the X-rays with different intensities; sectional images based on phase contrast are obtained through a three-dimensional reconstruction system; finally, components and interior fine structure information of the soft tissue samples are obtained. The system and method can be used for detecting soft tissue samples in the pathology department, the radiology department and the scientific research department of a hospital, early lesion information such as small lesions in the tissue samples can be found easily, and the detection rate is greatly increased.

The present invention is a process for preparing soft tissue such as tendons, ligaments, cartilage, fascia, dermis, human valves and human veins for implant in a human and removes cellular components and forms an decellular matrix having as major components collagens and elastins while sterilizing the tissue. The process comprises the following steps: (1) isolating from a suitable donor a desired soft tissue sample of the biological material; (2) processing and decellularizing the soft tissue including inspection for visual defects, trimming and soaking the tissue in a detergent depending on whether the tissue is fascia or dermis and rinsing same with sterile water; (3) sterilizing the soft tissue in a vacuum and soaking the tissue in an antibiotic composition or peracetic acid depending on whether the soft tissue is fascia or dermis and rinsing same; (4) processing the tissue by cutting the tissue to size and perforating the tissue; and (5) dipping the tissue in 70% ethanol and packaging the tissue.

The invention discloses a biomechanics test device for soft tissues of skin and a liquid loading test method. The biomechanics test device consists of a computer, a metering pump for driving liquid, a device provided with a liquid storage cavity and used for supporting a skin sample, a pressure sensor, a data acquisition card, a pressing sleeve for fixing the sample, a cylinder, a control valve, a pressure reducing valve and a pressure gauge, can carry out biomechanics test under the state that the soft tissue sample of the skin is similar to physiological environment of human body, and ensures that the pressure for clamping the soft tissue sample of the skin is moderate and the test is more accurate. The method for carrying out liquid loading test by adopting the biomechanics test device can obtain load and deformation state of the soft tissue sample of the skin through variation of pressure of loading liquid and flow volume, so as to obtain various biomechanics indexes of the soft tissue sample of the skin.

The invention belongs to the technical field of soft matter and experimental mechanics, and relates to a biological soft tissue mechanical property test clamping device based on vacuum adsorption. The device comprises a vacuum control loop, an air buffer, a test fixture and the like, wherein the test fixture consists of an upper chuck, a lower chuck, upper and lower chuck porous material plates, upper and lower chuck caps and the like; and L-shaped holes are formed in the upper and lower chucks. By utilizing the pressure difference action between the outside atmospheric pressure and the negative pressure of the L-shaped inner cavity of the upper and lower chucks, a biological soft tissue sample is adsorbed to the chucks. According to a reciprocating motion testing machine, static and dynamic loads are applied to the soft tissue sample by virtue of the fixture, and the mechanical property is tested. The device disclosed by the invention has the effects that the biological soft tissue sample is adsorbed to the chucks by utilizing the pressure difference action, and the accuracy of testing the mechanical property parameters of the animal soft tissue sample is improved. According to the controllable pressure, the device is applied to verifying the experimental repeatability and comparing different soft tissue mechanical properties. The device is high in controllability, convenient to operate and easy to produce and popularize.

The invention discloses a tactile interaction-based percutaneous nephrolithotomy (PCNL) kidney stone virtual surgical training system and a method for improving the repeated training of urologists soas to make the urologists obtain puncture skills. The system specifically includes a medical image three-dimensional reconstruction module (1), a kidney soft tissue sample puncture experiment module (2), a mechanical modeling module (3), a visual rendering module (4), a tactile rendering module (5), a virtual operation training environment design module (6), a tactile interaction device module (7), an operation training data acquisition and analysis module (8), an augmented reality module (9) and a 3D printing module (10). According to the system of the present invention, a real surgical trocar is adopted to puncture a kidney tissue, so that data can be obtained to be used for establishing a mechanical model; the system enables a strong sense of immersion and high real-time performance onthe basis of a virtual PCNL operation environment constructed through the tactile interaction device, the augmented reality technology and the 3D printing technology. With the system adopted, the training of the urologists can be facilitated, the operative skills of the urologists can be improved, and the urologists can be familiar with the procedures of an operation.

Disclosed relates to a waved implant integrating a soft tissue area and an osseous tissue area and, more particularly, to a soft tissue area and an osseous tissue area that prevents fine motion of an artificial tooth, intercepts the infiltration of bacteria in the vicinity of the implant and preserves the gingival shape of the natural tooth. Accordingly, it is possible to prevent fine motion of the artificial tooth, intercept the infiltration of bacteria in the vicinity of the implant and preserves the gingival shape of the natural tooth.

The invention discloses a stone filtering collector. The stone filtering collector comprises a cover and a main body, wherein the main body is provided with a cavity; the cover is provided with a connecting tube and communicates with an endoscopic sheath water outlet channel; a filtering device with a filter screen is arranged in the main body; the filtering device divides the cavity in the main body into a collecting cavity and a liquid draining cavity; the connecting tube communicates with the collecting cavity; and the liquid draining cavity is provided with a water draining tube. By the filtering collector which is connected with the endoscopic sheath water outlet channel, the purpose of filtering and separating mixed liquid is achieved while surgery is implemented, stone samples and soft tissue samples are directly extracted from the inside of the filtering device, work efficiency of medical workers is greatly improved, workload is reduced, the soft tissue samples can be effectively prevented from being lost, stone ingredient detection or soft tissue pathological examination can be finished effectively in time, and services can be provided for patients well subsequently.

This invention relates to a device (10) for taking at least one sample of soft tissue from an organ, said device comprising a body (11) and a needle (12) arranged in the body and extending at least partly outside the body through the front end of the body, the needle is formed by a stylet (13) and a cannula (14) coaxial with said stylet, said device comprising a mechanism for arming the needle, designed for sequentially moving the stylet (13) and then the cannula (14) from a rest position to a shooting position wherein the stylet and the cannula are retracted towards the rear end of the body, and a triggering mechanism designed to release the stylet then the cannula and to allow their displacement from the shooting position to the rest position, the cannula being coupled to a cannula slider comprising at least one retaining element for engaging with the cannula slider in a shooting position, the stylet being coupled to a stylet slider (30) comprising at least one retaining element (32) for engaging with the stylet slider in a shooting position and means for unlocking (34) the cannula slider, characterized in that the mechanism for arming the cannula further comprises means for separating the means (34) for unlocking the cannula slider and said retaining element (26) for engaging with the cannula and at least one security element (36) designed for engaging with the stylet slider (30) in a position in which the means (34) for unlocking the cannula slider is separated from the retaining element (26) for engaging with the cannula slider (24) in a shooting position.

This invention relates to a device (10) for taking at least one sample of soft tissue from an organ, said device comprising a body (11) and a needle (12) arranged in the body and extending at least partly outside the body through the front end of the body, the needle is formed by a stylet and a cannula coaxial with said stylet. The device comprises a mechanism for arming the needle, designed for sequentially moving the stylet and then the cannula from a rest position to a shooting position wherein the stylet and the cannula are retracted towards the rear end of the body, and a triggering mechanism designed to release the stylet then the cannula and to allow their displacement from the shooting position to the rest position. The cannula is coupled to a cannula slider (24) comprising at least one retaining element (26) for maintaining the cannula slider in a shooting position. The stylet is coupled to a stylet slider (30) comprising at least one retaining element (32) for maintaining the stylet slider in a shooting position and means for unlocking the cannula slider. This device is characterized in that the stylet slider (30) comprises a support device (41) integral with the stylet and a guide device (42) mobile in the body (11) of the device, in that the displacement of the guide device (42) leads to the displacement of the support device (41) and in that the support device (41) and the guide device (42) have a clearance between each other.

The invention provides a multifunctional biological in-vitro soft tissue parameter measurement platform. The multifunctional biological in-vitro soft tissue parameter measurement platform mainly comprises an experiment auxiliary platform and an experiment measurement platform. The multifunctional biological in-vitro soft tissue parameter measurement platform can perform four different experiments on a soft tissue, namely, a uniaxial compression experiment (a pressing head slowly presses down to a certain position), a stress relaxation experiment (the pressing head quickly presses down to a certain position and is kept for a period of time), a creep experiment (a steel wire rope suspends weights), and a soft tissue puncture experiment. Micro strain of a soft tissue sample is realized in the mode of driving the steel wire rope to drive by adopting a screw thread pair. According to the multifunctional biological in-vitro soft tissue parameter measurement platform, the problems that a material experiment machine can only be relied in soft tissue measurement and a measurement parameter is single are effectively solved, and the multifunctional biological in-vitro soft tissue parameter measurement platform has a certain popularization value.

This invention relates to a device (10) for taking at least one sample of soft tissue from an organ, said device comprising a body (11) and a needle (12) formed by a stylet (13) and a cannula (14) coaxial with said stylet, said device comprising a mechanism for arming the needle, designed for sequentially moving the cannula (14) and then the stylet (13) from a rest position wherein the stylet and the cannula are extended towards the outside of the body, to a shooting position wherein the stylet and the cannula are retracted towards the rear of the body, and a triggering mechanism designed to release the stylet then the cannula and to allow their displacement from the shooting position to the rest position, the cannula being coupled kinematically to a cannula slider (24) comprising at least one retaining element (26) for maintaining the cannula slider in a shooting position, the stylet being coupled kinematically to a stylet slider (30) comprising at least one retaining element (32) for maintaining the stylet slider in a shooting position and means for unlocking (34) the cannula slider. At least one of said retaining elements of the cannula slider (26) or stylet slider (32) comprises at least a hook (50) arranged to rest against a corresponding retaining element (27, 33) in a locking position and to release the retaining element (27, 33) in a shooting position. The retaining element is unhooked from said retaining means by a striker (51), this striker comprising elastic blades (52) which number is at least equal to the number of hooks of said retaining element, these elastic blades (52) being arranged to be in contact with said hooks. The striker (51) cooperates with a stressing ring (53) arranged around the elastic blades (52) of the striker (51), this stressing ring (53) being arranged to be movable in a first stressing position, in which said ring acts on the elastic blades (52) of the striker and forces them in order to allow a sufficient force to be applied to the hooks (50) of the retaining element, and a second free position, in which said stressing ring (53) does not apply a sufficient stress to the hooks (50) for unhooking the hooks from the retaining means.

The invention discloses a medical soft tissue collator. The medical soft tissue collator comprises a workbench, the workbench is provided with an chopping board, at least one adjusting base, a trimming groove and at least one hole seat, wherein the adjusting base is arranged on a long side of the chopping board, the trimming groove is arranged on a short side of the chopping board, the workbench is provided with at least one slideway, the slideway is provided in cooperation with the adjustment base, and the hole seat is disposed at one end close to the short side of the workbench. The medicalsoft tissue collator is based on the workbench and is provided with a hook piece, a soft tissue clamp, a winding fixer, a titanium plate fixer, a tensioner and other accessories. By freely assemblingdifferent accessories on the workbench, the medical soft tissue collator can meet different needs of doctors during an operation, reduce difficulties of the operation and improve efficiency of the operation.

This invention relates to a device (10) for taking at least one sample of soft tissue from an organ, said device comprising a body (11) and a needle (12) formed by a stylet (13) and a cannula (14) coaxial with said stylet, said device comprising a mechanism for arming the needle, designed for sequentially moving the cannula (14) and then the stylet (13) from a rest position wherein the stylet and the cannula are extended towards the outside of the body, to a shooting position wherein the stylet and the cannula are retracted towards the rear of the body, and a triggering mechanism designed to release the stylet then the cannula and to allow their displacement from the shooting position to the rest position, the cannula being coupled kinematically to a cannula slider (24) comprising at least one retaining element (26) for maintaining the cannula slider in a shooting position, the stylet being coupled kinematically to a stylet slider (30) comprising at least one retaining element (32) for maintaining the stylet slider in a shooting position and means for unlocking (34) the cannula slider. In this device, at least one element among said retaining element of the cannula slider (26) and said retaining element of the stylet slider (32) comprises at least one hook (51), this hook comprising at least an elastic blade (52) arranged for resting against a corresponding retaining device (27, 33) in a locking position and for being released from the corresponding retaining device (27, 33) in a shooting position, said elastic blade (52) having at least one bending area (53) around which this elastic blade is bent under the action of a stress, and said bending area (53) is placed at the rear of said corresponding retaining device (27, 33).

The invention discloses a method for detecting the density distribution of microplastics in soft tissues of marine organisms, and belongs to the field of microplastics in fish or bivalve biological samples. A method for detecting the density distribution of microplastics in soft tissues of marine organisms. The steps include: selecting fish or bivalve organisms that are close to each other, washing them with pure water to prepare digestive tract or soft tissue samples, and recording the weight; preparing a digestion solution to The prepared sample is digested and the digestion mixture is obtained; NaCl is added to the mixture for density flotation; the flotation particles are microscopically inspected, and suspected particles are selected for micro-Fourier spectroscopy analysis to identify microplastics. After counting, the density distribution of microplastics is calculated. The invention can accurately quantify microplastics in the digestive tract or soft tissue of marine organisms and provide basic data on the pollution status of microplastics in the area.

The invention relates to a soft tissue puncture force modeling method based on segmented artificial neural networks, including the following steps: 1) selecting a soft tissue sample to be modeled forpuncture experiment to collect sample data; 2) analyzing and sorting the sample data, dividing all the data into before puncture, after puncture, and to the deepest point according to the puncture stage, and pulling out three groups, and dividing each group of data into a training group and a test group; 3) using the training group for neural network training, and then using the test group to evaluate the neural networks; and 4) calling the three neural networks obtained by training in a segmented way according to the puncture stage to complete modeling. The soft tissue puncture force modelingmethod based on segmented artificial neural networks has the advantages that being small in the prediction error of modeling, and being within the range of being difficult to be detected by human hands; being easy for modeling is easy, being time-saving and laborsaving; being able to mechanically model the complete process of soft tissue puncture, and being able to preferably complete modeling even in the most nonlinear phase; and having a certain universal applicability to the same tissue of different individuals for the model, wherein the overall predictive power trend is consistent with the experimental data.

This invention relates to a device (10) for taking at least one sample of soft tissue from an organ, said device comprising a body (11) and a needle (12) formed by a stylet (13) and a cannula (14) coaxial with said stylet, said device comprising a mechanism for arming the needle, designed for sequentially moving the cannula (14) and then the stylet (13) from a rest position wherein the stylet and the cannula are extended towards the outside of the body, to a shooting position wherein the stylet and the cannula are retracted towards the rear of the body, and a triggering mechanism designed to release the stylet then the cannula and to allow their displacement from the shooting position to the rest position, the cannula being coupled kinematically to a cannula slider (24) comprising at least one retaining element (26) for maintaining the cannula slider in a shooting position, the stylet being coupled kinematically to a stylet slider (30) comprising at least one retaining element (32) for maintaining the stylet slider in a shooting position and means for unlocking (34) the cannula slider. At least one of said retaining elements of the cannula slider (26) or stylet slider (32) comprises at least a hook (50) arranged to rest against a corresponding retaining element (27, 33) in a locking position and to release the retaining element (27, 33) in a shooting position. The retaining element is unhooked from said retaining means by a striker (51), this striker comprising elastic blades (52) which number is at least equal to the number of hooks of said retaining element, these elastic blades (52) being arranged to be in contact with said hooks. The striker (51) cooperates with a stressing ring (53) arranged around the elastic blades (52) of the striker (51), this stressing ring (53) being arranged to be movable in a first stressing position, in which said ring acts on the elastic blades (52) of the striker and forces them in order to allow a sufficient force to be applied to the hooks (50) of the retaining element, and a second free position, in which said stressing ring (53) does not apply a sufficient stress to the hooks (50) for unhooking the hooks from the retaining means.

This invention relates to a device (10) for taking at least one sample of soft tissue from an organ, said device comprising a body (11) and a needle (12) formed by a . stylet and a cannula coaxial with said stylet. The device comprises a mechanism for arming the needle, designed for sequentially moving the cannula and then the stylet from a rest position wherein the stylet and the cannula are extended towards the outside of the body, to a shooting position wherein the stylet and the cannula are retracted towards the rear of the body, and a triggering mechanism designed to release the stylet then the cannula and to allow their displacement from the shooting position to the rest position. The cannula is coupled kinematically to a cannula slider (24) comprising at least one retaining element (26) for maintaining the cannula slider in a shooting position. The stylet is coupled kinematically to a stylet slider (30) comprising at least one retaining element (32) for maintaining the stylet slider in a shooting position and means for unlocking the cannula slider. This device is characterized in that the stylet (13) comprises a sampling tip (51) able to slide into the cannula (14) and a displacement rod (42) connecting said sampling tip with the stylet slider (30), the sampling tip (51) being separate from the displacement rod (42).

The invention relates to a soft tissue cylindrical sample cutting tool device and an application thereof. The device comprises a tubular knife, the tubular knife is connected with two telescopic knives, the two telescopic knives are respectively arranged at two sides of the tubular knife, and the tool bits of the two telescopic knives are arranged oppositely; and when a soft tissue enters the tubular knife, the two telescopic knives simultaneously enter the tubular knife, and cut off the middle part of the soft tissue. The cutting tool device realizes one-shot molding of a soft tissue sample, so the change of a cutting reference in the fetching and placing process is avoided, the cutting error caused by deformation of the soft tissue is reduced, and the efficiency of the whole experiment is improved. The cutting tool device has the advantages of ingenious structure design, simplicity in operation, low cost, realization of series production to meet requirements of soft tissue cylindrical samples having different lengths, obvious effect and excellent effect.