Biomechanics test device for skin soft tissue and its liquid loading test method

Abstract

The invention discloses a biomechanics test device for soft tissues of skin and a liquid loading test method. The biomechanics test device consists of a computer, a metering pump for driving liquid, a device provided with a liquid storage cavity and used for supporting a skin sample, a pressure sensor, a data acquisition card, a pressing sleeve for fixing the sample, a cylinder, a control valve, a pressure reducing valve and a pressure gauge, can carry out biomechanics test under the state that the soft tissue sample of the skin is similar to physiological environment of human body, and ensures that the pressure for clamping the soft tissue sample of the skin is moderate and the test is more accurate. The method for carrying out liquid loading test by adopting the biomechanics test device can obtain load and deformation state of the soft tissue sample of the skin through variation of pressure of loading liquid and flow volume, so as to obtain various biomechanics indexes of the soft tissue sample of the skin.

Description

technical field [0001] The invention relates to the field of testing biomechanical properties of skin, in particular to a biomechanical testing device and a liquid loading testing method for skin soft tissue. Background technique [0002] As a special nonlinear viscoelastic biomaterial, skin soft tissue has a complex structure and special functions, so its biomechanical analysis is more complicated than the mechanical property test of ordinary materials, and the test methods required are more cumbersome . Especially with the development of tissue engineering technology, the development and application of tissue engineered skin has gradually improved. However, the biomechanical properties of tissue engineered skin cultivated by tissue engineering technology must be tested for biomechanical properties of tissue engineered skin. [0003] At present, the existing skin biomechanical tests usually use two-dimensional tensile testing, steel stamp extrusion testing, air pressure te...

AI Technical Summary

Problems solved by technology

The test method using this air pressure detection device can obtain the breakdown pressure data of the block sample, which is a certain improvement compared with the two-dimensional tensile test method, but there are still the following deficiencies: one is to use air pressure to test the mechanical properties of the skin , due to the obvious compressibility of air, the air pressure collected by the pressure transmitter cannot accurately reflect the maximum pressure that the test skin can withstand when the test skin is broken down

The second is to use air pressure to test the skin. The skin is in the air environment, which is obviously different from the physiological conditions. The measured data has a certain gap with the data tested under physiological conditions, which cannot truly reflect the mechanical properties of the skin under physiological conditions.

The third is that the device for fixing the test sample adopts a sample fixing ring that matches the truncated conical sample loading platform. On the frustum-shaped sample loading platform, this fixing method adopts constant pressure or constant gap, which has great limitations. If the fixing pressure is low and the fixing is loose, the test sample will easily slip and affect the test results; if the fixing pressure If it is too high, the fixation will be too tight, and it will easily cause the test sample to be squeezed and damaged to affect the test. Therefore, this device is only suitable for the fixation of thin film skin samples, and can only detect the small tension of thin film samples.

Fourth, this device and test method cannot obtain the deformation process of the test skin soft tissue.

In view of these reasons, it is difficult for this air pressure detection device and method to meet the requirements of different skins and different test items, and can only obtain a single mechanical characteristic parameter of the tensile strength of the skin membrane, which is one of the important indicators of skin viscoelasticity. The stress-strain curve of skin soft tissue that reflects the ability of skin tissue deformation cannot be detected, which is difficult to meet the needs of scientific research and clinical practice

In addition, in order to obtain the biological characteristic parameters of the skin deformation process, there is an existing technology that uses a CCD camera to obtain the skin deformation process, but this method needs to collect multiple frames of images, and it takes a long time to analyze the multiple frames of images processing, not only the testing process is cumbersome, but also the current technology cannot achieve real-time detection and analysis, and it is also easy to introduce errors

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