The invention is a pollutant aerobic-biodegradation breathing measuring method and device, relating to a method and device for measuring oxygen utilization ratio in the course of processing waste water by aerobes. And the measuring method comprises the steps of: checking dissolved oxygen sensor, keeping temperature of water tank constant, putting in microbial mixed solution, blending, circulating mixed solution, setting parameters, putting in to-be-measured sample and calculating; and the measuring device comprises water tank, magnetic blending mechanism, aeration mechanism, aeration chamber, breathing chamber, measuring chamber, pH sensor, dissolved oxygen sensor, signal transmit lines, transducer terminal box, computer and oxygen utilization ratio measuring software. And the invention has advantages of less interference, high testing accuracy and frequency, high instrument automation degree, etc. and it is applied to the aspects of city sewage composition characterization, inlet water toxicity detection, evaluation and early- warning in sewage factory, process control and operation management in sewage factory, etc.