31 results about "Marasmius androsaceus" patented technology

A capsule for treating rheumatic or rheumatoid arthritis, osteoarthritis, hyperosteogeny, periomethritis, lumbar muscle strain, etc. is prepared from 4 raw materials including Chinese trumpetcreeper flower 3000 g, piroxicam 10g, VB1 30 g and marasmius androsaceus 100g.

The invention relates to a medicine composition for treating arthritis and gout, which is characterized by being prepared from traditional Chinese medicine raw materials according to the weight proportion: 0.1-15g of artemisia anomala, 0.1-15g of the bark of ash, 0.1-15g of thunberg fritillary bulb, 0.1-30g of wild chrysanthemum flower, 0.1-30g of pseudo-ginseng, 0.1-30g of scandent schefflera root, 0-30g of astragalus root, 0-15g of lghtyellow sophora root, 0-15g of kadsura pepper stem and 0-15g of marasmius androsaceus. The invention also discloses a preparation method, a preparation and application of the medicine composition. The invention has better safety, can effectively lower the concentration of uric acid, can remarkably relive the pain and resist the inflammation, and is suitable for treatment of arthritis and gout, especially treatment of gout subacute stage.

The invention discloses a selenium-enriched marasmius androsaceus toadstool extract preparation which is prepared by the steps that: based on marasmius androsaceus toadstool as a carrier for enriching selenium element, a liquid submerged fermentation technology is adopted, 10-30mg / ml of sodium selenite (Na2SeO3.5H2O) is added into mycelium and metabolite of the marasmius androsaceus toadstool in the growth process according to the volume weight ratio, so that the selenium content in the cultured product of the marasmius androsaceus toadstool reaches 240-400mu g / g; and an excipient is added according to the conventional technology, so that the selenium-enriched marasmius androsaceus toadstool extract preparation is prepared. The selenium-enriched marasmius androsaceus toadstool extract preparation can be used as a medicine for treating multiple pain diseases such as nervous headache, pain in waist and lower extremities, sciatica and the like, and is remarkable in treatment effect; compared with the similar medicines, the selenium-enriched marasmius androsaceus toadstool extract preparation has the characteristics of being high in cure rate, free from side effect or addiction and the like; and the selenium-enriched marasmius androsaceus toadstool extract preparation is simple in production technique, convenient in operation and remarkable in selenium enrichment effect, and has potential application and development values.

The invention discloses a medicament for treating lumbar muscle scleredema with strain. The medicament is prepared from the following main raw materials in parts by weight: 6-12 parts of Chinese angelica, 5-15 parts of radix paeoniae rubra, 6-15 parts of moutan bark, 3-9 parts of safflower, 5-16 parts of teasel root, 6-12 parts of rhizoma atractylodis macrocephalae, 2-4 parts of marasmius androsaceus, 8-16 parts of poria cocos, 5-18 parts of radix achyranthis bidentatae, 10-16 parts of scutellaria baicalensis, 6-15 parts of trogopterus dung, 3-6 parts of liquorice, 4-10 parts of rhizoma sparganii and 6-15 parts of pollen pini. The medicament is developed against lumbar muscle scleredema with strain, can be used for effectively treating lumbar muscle scleredema and lumbar muscle strain, has the effects of dredging tendons and activating blood, diminishing inflammation and relieving pain, and is safe and reliable by selecting traditional Chinese medicinal materials as raw materials.

The invention discloses a method for producing marasmius androsaceus fermented powder by adopting an optimized solid culture medium, belonging to the field of biological fermentation, providing rich nutrient substances for strain culture and solving the problems of long culture time and low mycelium yield. The method for producing marasmius androsaceus fermented powder by adopting the optimized solid culture medium comprises the following steps of sterilizing a solid culture medium; inoculating, culturing; extracting; concentrating and powdering, wherein the solid culture medium is prepared from the following components in parts by weight: 50-80 parts of wheat bran, 20-30 parts of rice hull, 5-20 parts of oral glucose, 0.05-0.2 part of potassium dihydrogen phosphate, 0.025-0.1 part of magnesium sulfate and the balance of water, wherein various inorganic potassium salts, especially potassium phosphate can be used as a potassium source. The substances have the stimulation action on the growth of marasins so that short culture time, high mycelium yield and shortened production time are achieved. The solid culture medium of the invention has cheap and easily-obtainable raw material components and low cost and is suitable for industrialized production.

The invention discloses a method for efficiently preparing inhomogenous Marasmius androsaceus polysaccharide through a membrane separation technology. The method comprises the following steps: 1, performing submerged fermentation to obtain a fermentation liquor; 2, freeze-drying the fermentation liquor to reach constant mass, crushing by using a crusher, and sieving by using a 60-mesh sieve; 3, leaching by using a constant temperature water bath; 4, concentrating and purifying by using an inorganic ceramic microfiltration membrane; 5, concentrating and purifying by using an inorganic ceramic ultrafiltration membrane with the molecular weight cutoff of 4,000-9,000k; 6, removing proteins from an inhomogenous Marasmius androsaceus polysaccharide solution in the step 5 by using a sevage liquid; and 7, spray-drying the inhomogenous Marasmius androsaceus polysaccharide solution in the step 6 to obtain powder, thus obtaining the inhomogenous Marasmius androsaceus polysaccharide product, wherein the inlet temperature for the spray drying is 170-210DEG C and the outlet temperature is 80-95DEG C. The preparation method is low in cost; and the prepared product has high quality and long quality guarantee period and can be stored for more than two years without deterioration under the sealed condition.

The invention discloses medicine liquid for curing cervical spondylosis and a preparing method thereof. The medicine liquid uses 500 portions of white spirit as liquor base, and materials with weight portion as followed are added: one to five portions of marasmius androsaceus, one to five portions of halimasch, half to three portions of concretio silicea bambusae, one to six portions of qalanga, and half to three portions of zaocys dhumnade. The preparing method is that the raw material is weighed, which is then broken up and evenly mixed; white spirit is added for soaking; after being filtered, the medicine wine is filled. The medicine wine of the invention uses the medical epiphyte with the function of relaxing the muscles and stimulating the blood circulation, and diminishing inflammation and relieving pain and traditional Chinese medicinal herb as raw materials; wine is added so the medicine is characterized by acridity and the taste of the medicine liquid is bitter and sweet. The medicine liquid has function for the four channels, liver, heart, spleen, and stomach, which can drain channels and collaterals, warm channels and help the medicine to work so that the efficacy of drug can reach the channels around the whole body; the medicine liquid can help the medicine to invigorate blood circulation and promote blood circulation, expel wind and clear away cold and finally realize the function of stimulating skeleton energy, fully replenishing and maintaining skeleton nutrition, improving bone density, renovating flexibility of skeleton and ligament, softening spur and relieving pain. The healing of cervical spondylosis can be realized fundamentally.

The invention discloses a method for efficiently preparing inhomogenous Marasmius androsaceus polysaccharide through a membrane separation technology. The method comprises the following steps: 1, performing submerged fermentation to obtain a fermentation liquor; 2, freeze-drying the fermentation liquor to reach constant mass, crushing by using a crusher, and sieving by using a 60-mesh sieve; 3, leaching by using a constant temperature water bath; 4, concentrating and purifying by using an inorganic ceramic microfiltration membrane; 5, concentrating and purifying by using an inorganic ceramic ultrafiltration membrane with the molecular weight cutoff of 4,000-9,000k; 6, removing proteins from an inhomogenous Marasmius androsaceus polysaccharide solution in the step 5 by using a sevage liquid; and 7, spray-drying the inhomogenous Marasmius androsaceus polysaccharide solution in the step 6 to obtain powder, thus obtaining the inhomogenous Marasmius androsaceus polysaccharide product, wherein the inlet temperature for the spray drying is 170-210DEG C and the outlet temperature is 80-95DEG C. The preparation method is low in cost; and the prepared product has high quality and long quality guarantee period and can be stored for more than two years without deterioration under the sealed condition.

The invention provides a solid culture medium for marasmius androsaceus and a preparation method of dried marasmius androsaceus thalli. The solid culture medium comprises the following components in parts by weight: 40-55 parts of wheat bran, 18-25 parts of corn flour, 2-5 parts of soybean meal, 0.5-2 parts of calcium salt powder, 20-30 parts of rice husk, 1-5 parts of white granulated sugar, 0.01-0.2 part of potassium dihydrogen phosphate, 0.01-0.2 part of magnesium sulfate and 80-100 parts of water. The preparation method comprises the following steps: 1, preparing and sterilizing the solidculture medium; 2, inoculating; 3, culturing; 4, drying. In the dried marasmius androsaceus thalli cultured by utilizing the culture medium, the contents of effective substances such as proteoglycan in an ethanol extract and a water-dissolved product of the marasmius androsaceus are greatly increased; the growth speed has an obvious advantage.

The invention discloses a prescription for treating conjunctival xerosis, which is mainly prepared from the following bulk drugs in parts by weight: 15-25 parts of seed of feather cockscomb, 20-30 parts of buddleja officinalis, 10-20 parts of concha haliotidis, 1-5 parts of magnetite, 8-16 parts of equisetum hiemale, 3-9 parts of lycorma delicatula white, 6-9 parts of root of littleleaf dogwood, and 4-12 parts of marasmius androsaceus. According to the invention, the selected materials are all traditional Chinese medicine materials, have no toxic or side effects; the prescription completely conforms to principles of the traditional Chinese medicine and the mind and body characteristics of patients suffering from conjunctival xerosis and trachoma; under the premise of the general principle, different prescription can be adopted for different crowds to achieve different functions; the medicinal herb resources are easy to obtain, and the cost of medicinal materials is low, so that the burden of patients can be alleviated.

The invention belongs to the technical field of microbes, particularly relates to method for producing marasmius androsaceus (L. ex Fr.) Fr. extracellular polysaccharide through submerged liquid state fermentation, and in particular to a production method for marasmius androsaceus (L. ex Fr.) Fr. extracellular polysaccharide in an industrialization scale. The method comprises the following steps: conducting expanded matching on activated marasmius androsaceus (L. ex Fr.) Fr. strains through inoculating into a seeding tank, inoculating the liquid seeds subjected to expanded matching to a tailor-made liquid culture medium capable of producing polyose to conduct fermentation, separating the fermentation liquor, and extracting the extracellular polysaccharide. The invention aims to conduct a study on the deficiencies in the prior art, on the basis of continuously optimizing a fermentation culture medium (in particular to a carbon source), improving the biomass and the extracellular polysaccharide in a small-scale test and a pilot scale test, the problems such as parameter control in the fermentation process, extracting equipment lectotype, optimization and the like in the process from the small-scale test to the industrialized production are solved, finally, the marasmius androsaceus (L. ex Fr.) Fr. strains are grafted onto 10-20 t fermentation tanks to conduct industrialized production, and the marasmius androsaceus (L. ex Fr.) Fr. polyose with high quality is produced smoothly, so that the production with continuity, automatization, and industrialization is realized really and truly.

The invention relates to the field of a pharmaceutical formulation, and in particular discloses a traditional Chinese medicine for promoting recovery of lumbar muscle strain. The traditional Chinese medicine is characterized by being prepared from the following medicinal raw materials in parts by weight: 30-50 parts of thyme, 5-10 parts of sharptooth incarvillea rhizome and herb, 10-20 parts of scarlet kadsura root, 10-20 parts of mandrake, 10-20 parts of burmann cinnamon bark, 10-30 parts of petelot habenaria, 20-40 parts of common trumpetcreeper flower, 10-20 parts of peruvian groundcherry herb, 5-25 parts of marasmius androsaceus, 5-25 parts of geraniumwilfordii maxim, 5-20 parts of all-grass of climbing violet, 5-20 parts of fructus broussonetiae, 5-20 parts of oriental blueberry root, 5-20 parts of tuniclike psammosilene root, 5-25 parts of herba rostellulariae and 10-30 parts of ramie bark. The 16 medicinal raw materials are soaked in water and are decocted, and dregs are removed, so that a filtrate is obtained. The traditional Chinese medicine disclosed by the invention, by combining the various medicinal materials, has functions of tonifying liver and spleen, strengthening waist and knees, expelling wind-damp and strengthening joints; on treating lumbar muscle strain, the traditional Chinese medicine has the advantages of being rapid to take effect, high in cure rate, free from toxic and side effects, safe and convenient; and the traditional Chinese medicine can be widely applied to clinical treatment of lumbar muscle strain.

The invention discloses a composition for treating acute pancreatitis, which is prepared from the following main raw materials in parts by weight: 1-3 parts of calcite, 9-30 parts of marasmius androsaceus(Fr.)Fr, 12-30 parts of felwort, 15-30 parts of Chinese yam, 6-12 parts of soybean, 5-15 parts of longan, 6-15 parts of natural indigo, 7-15 parts of coriander, 20-50 parts of rhubarb, 3-9 parts of shallot, 9-15 parts of motherwort fruit, 15-30 parts of isatis root, 3-15 parts of curcuma (preferably 3.5-14.5 parts of curcuma) and 3-8 parts of peanut kernels. The composition disclosed by the invention can be used for treating acute pancreatitis, can also play roles in building the body, sterilizing germs and diminishing inflammation, and is prepared by combining medicines with effects on improving immunity, treating abdominal distention and treating pancreatitis.

The invention discloses a method for producing marasmius androsaceus mycelia polysaccharides by efficient extraction and submerged liquid-state fermentation. The method comprises the steps of treating mycelia separated from marasmius androsaceus fermentation liquor by ultrasonic waves and composite enzymatic hydrolysis, and separating to obtain marasmius androsaceus polysaccharides. The method disclosed by the invention improves the conventional extracting mode of polysaccharide water extraction by alcohol sedimentation, improves extracting yield and product quality of marasmius androsaceus polysaccharides, reduces dosage of purified water and energy consumption in production, and increases economic benefits.

The invention provides marasmius androsaceus exopolysaccharide and an application thereof, and belongs to the technical field of biological extraction. The molecular weight of the marasmius androsaceus exopolysaccharide is 10.47 kDa, wherein the molar ratio of mannose to glucose to galactose in the monosaccharide composition is 0.08: 0.34: 1.46. The marasmius androsaceus exopolysaccharide is extracted from marasmius androsaceus fermentation liquor for the first time, is novel in structure, has a good anti-fatigue effect by adopting an animal experiment to test MEPS3 polysaccharide, and is mainly used for preparing anti-fatigue medicines, health care products and the like.

The invention discloses an external application patch for treating traumatic injuries. The preparation method of the external application patch is prepared from the following main raw materials in parts by weight: 8-18 parts of dinodon rufozonatum, 6-12 parts of radix et rhizoma veratri, 6-12 parts of frankincense, 9-15 parts of radix angelicae pubescentis, 3-6 parts of pyritum, 5-10 parts of radix chloranthi serrate, 6-10 parts of marasmius androsaceus, 5-12 parts of dog's bone, 9-15 parts of radix gentianae macrophyllae and 6-9 parts of beaumontia grandiflora. The external application patch is based on the principle that the traumatic injuries are treated with traditional chinese medicines, an external application preparation is adopted, and drugs are enabled to directly act on parts with traumatic injuries through local permeation of the drugs, so that active ingredients of the drugs are directly sent to focus parts to have a good treatment effect on the traumatic injuries.

The invention discloses an externally-applied preparation for treating a patella injury. The externally-applied preparation is prepared from the following rw materials in parts by weight: 3-7 parts of pyrolusite pyrolusitum, 15-19 parts of dioscorea nipponica makino, 5-15 parts of dysosma versipellis, 6-16 parts of Chinese prickly ash, 5-18 parts of flos carthami, 3-9 parts of tropic ageratum herb, 9-18 parts of honeysuckle flower, 8-14 parts of serrate chloranthus root, 3-9 parts of marasmius androsaceus, 2-8 parts of acanthopanax, 10-30 parts of ligusticum wallichii, 1-3 parts of rhizoma drynariae and 10-20 parts of notopterygium roots. The externally-applied preparation has significant treatment effect on the patella injury; these medicines are combined to generate a synergistic effect; the externally-applied preparation has the efficacies of activating blood, removing stasis, dredging collaterals, setting a fracture, easing pain and strengthening muscles and bones, so as to effectively treat the patella injury. Local common medicinal materials are mainly selected, so that the price is low; and the economical burden of patients is relieved.

The invention discloses a botanical fungicide for smut disease. The fungicide comprises the following components in parts by weight: 20-30 parts of an ambrette extract, 15-25 parts of an abelmoschus esculentus extract, 10-20 parts of an avocado extract, 25-35 parts of a marasmius androsaceus extract, 30-40 parts of a mongolian dandelion herb extract, 20-30 parts of durian powder, 15-25 parts of a mesona fermented concentrate, 5-15 parts of malt and 10-20 parts of radix paeoniae rubra. Through the adoption of the manner, the botanical fungicide can effectively prevent and treat smut disease, can effectively reduce pesticide residue, and is free of damage to human health.

The invention discloses a medicinal liquor for treating sciatica and lumbar muscle strain. The medicinal liquor is prepared through the following main raw materials in parts by weight: 6-12 parts of angelica sinensis, 5-15 parts of radix paeoniae rubra, 6-15 parts of cortex moutan radicis, 3-9 parts of safflower, 5-16 parts of radix dipsaci, 3-9 parts of radix clematidis, 2-4 parts of marasmius androsaceus, 5-18 parts of radix achyranthis bidentatae, 3-9 parts of radix aucklandiae, 6-10 parts of radix aconiti agrestis, 3-6 parts of liquorice and 5-9 parts of cortex eucommiae. The medicinal liquor disclosed by the invention has the advantages of quick effect, short treatment course and high cure rate, has the effects of relaxing tendons and activating collaterals, warming meridians to dissipate cold, as well as promoting blood circulation and stopping pain and is safe and reliable without any toxic or side effect.

The invention relates to a medicine composition for treating arthritis and gout, which is characterized by being prepared from traditional Chinese medicine raw materials according to the weight proportion: 0.1-15g of artemisia anomala, 0.1-15g of the bark of ash, 0.1-15g of thunberg fritillary bulb, 0.1-30g of wild chrysanthemum flower, 0.1-30g of pseudo-ginseng, 0.1-30g of scandent schefflera root, 0-30g of astragalus root, 0-15g of lghtyellow sophora root, 0-15g of kadsura pepper stem and 0-15g of marasmius androsaceus. The invention also discloses a preparation method, a preparation and application of the medicine composition. The invention has better safety, can effectively lower the concentration of uric acid, can remarkably relive the pain and resist the inflammation, and is suitable for treatment of arthritis and gout, especially treatment of gout subacute stage.

The invention discloses a selenium-enriched marasmius androsaceus toadstool extract preparation which is prepared by the steps that: based on marasmius androsaceus toadstool as a carrier for enriching selenium element, a liquid submerged fermentation technology is adopted, 10-30mg / ml of sodium selenite (Na2SeO3.5H2O) is added into mycelium and metabolite of the marasmius androsaceus toadstool in the growth process according to the volume weight ratio, so that the selenium content in the cultured product of the marasmius androsaceus toadstool reaches 240-400mu g / g; and an excipient is added according to the conventional technology, so that the selenium-enriched marasmius androsaceus toadstool extract preparation is prepared. The selenium-enriched marasmius androsaceus toadstool extract preparation can be used as a medicine for treating multiple pain diseases such as nervous headache, pain in waist and lower extremities, sciatica and the like, and is remarkable in treatment effect; compared with the similar medicines, the selenium-enriched marasmius androsaceus toadstool extract preparation has the characteristics of being high in cure rate, free from side effect or addiction and the like; and the selenium-enriched marasmius androsaceus toadstool extract preparation is simple in production technique, convenient in operation and remarkable in selenium enrichment effect, and has potential application and development values.

The invention discloses an agent for treating lumbar muscle degeneration accompanied by sciatica. The agent is prepared from the following main raw materials in parts by weight: 6-12 parts of Angelica sinensis, 5-15 parts of root of common peony, 6-15 parts of moutan bark, 3-9 parts of red flower, 5-16 parts of teasel root, 3-9 parts of radix clematidis, 2-4 parts of Marasmius androsaceus, 2-6 parts of earthworm, 5-18 parts of the root of bidentate achyranthes, 3-9 parts of elecampane, 5-12 parts of madder, 3-6 parts of liquorice and 4-8 parts of Uniflower Swisscentaury Root. The agent has the effects of relieving pain and dredging muscles and bones, has an obvious treatment effect on patients suffering from lumbar muscle degeneration accompanied by sciatica and is scientific in prescription, simple in preparation method, convenient to operate, safe and reliable.

The present invention provides medical application of Marasmius androsaceus sp. T08 to the preparation of analgesic drugs. The Marasmius androsaceus sp. is subjected to fermentation, ethanol extraction and vacuum drying to prepared a Marasmius androsaceus sp. T08 extractive. Animal experiments prove that the Marasmius androsaceus sp. T08 extractive has significant analgesic activity. The preparation method in the invention is simple and low cost, and can be applied to preparation of analgesic drugs.

The invention discloses an absorption promoter for improving the bioavailability of tryptophan and other polysaccharide medicines. The absorption promoter of tryptophan, phenylalanine, baicalin, ginseng stem and leaf total saponins and other polysaccharide medicines is combined with tremella polysaccharides, Marasmius androsaceus polysaccharides and other polysaccharide medicines, so the gastrointestinal tract absorption and in-blood ability of the polysaccharide medicines is promoted, the bioavailability of polysaccharide medicines is improved, the problems of difficult oral absorption and low bioavailability of the polysaccharide medicines are solved, and the activity and the curative effects of the oral polysaccharide medicines are improved.

The invention discloses medicinal liquor for treating rheumatoid arthritis. The medicinal liquor is prepared from the following raw medicinal materials in parts by weight: 2-7 parts of rhizoma dioscoreae nipponicae, 3-9 parts of largeleaf dogwood barks, 1-5 parts of krait, 10-20 parts of star-flower lysimachia, 15-30 parts of gastrodia elata, 5-10 parts of marasmius androsaceus, 13-18 parts of liquorice, 20-30 parts of sea-buckthorn, 6-12 parts of radix angelicae pubescentis, 15-40 parts of rhizoma drynariae, 3-9 parts of homalomena occulta, 5-15 parts of achyranthes bidentata and 5-13 parts of hematoxylon. The medicinal liquor disclosed by the invention has the functions of treating rheumatoid arthritis, relaxing the muscles and stimulating the blood circulation, dispelling wind and removing obstruction in the meridians, promoting blood circulation to remove blood stasis, tonifying kidney and strengthening bones and enhancing the immunity. According to the medicinal liquor disclosed by the invention, the medicinal materials are easily available in source, so that the medical liquor is low in cost, and almost selected medicinal materials are matters with mild drug properties, so that the medicinal liquor drunk and nourished on a long-term no longer increases the economical and physical burdens of a user.

The invention discloses an agent for treating lumbar muscle degeneration accompanied by sciatica. The agent is prepared from the following main raw materials in parts by weight: 6-12 parts of Angelica sinensis, 5-15 parts of root of common peony, 6-15 parts of moutan bark, 3-9 parts of red flower, 5-16 parts of teasel root, 3-9 parts of radix clematidis, 2-4 parts of Marasmius androsaceus, 2-6 parts of earthworm, 5-18 parts of the root of bidentate achyranthes, 3-9 parts of elecampane, 5-12 parts of madder, 3-6 parts of liquorice and 4-8 parts of Uniflower Swisscentaury Root. The agent has the effects of relieving pain and dredging muscles and bones, has an obvious treatment effect on patients suffering from lumbar muscle degeneration accompanied by sciatica and is scientific in prescription, simple in preparation method, convenient to operate, safe and reliable.

The present invention provides medical application of Marasmius androsaceus sp. T08 to the preparation of analgesic drugs. The Marasmius androsaceus sp. is subjected to fermentation, ethanol extraction and vacuum drying to prepared a Marasmius androsaceus sp. T08 extractive. Animal experiments prove that the Marasmius androsaceus sp. T08 extractive has significant analgesic activity. The preparation method in the invention is simple and low cost, and can be applied to preparation of analgesic drugs.

A capsule for treating rheumatic or rheumatoid arthritis, osteoarthritis, hyperosteogeny, periomethritis, lumbar muscle strain, etc. is prepared from 4 raw materials including Chinese trumpetcreeper flower 3000 g, piroxicam 10g, VB1 30 g and marasmius androsaceus 100g.