110 results about "Host bone" patented technology

The present invention comprises the provision and use of a novel retainer which is slidably advanced to a desired fixation position within a bone tunnel, fixed in position within the bone tunnel (preferably by wedging and / or pinning) while applying a lateral force against the graft ligament so as to compressively hold the graft ligament against the sidewall of the bone tunnel, and which then, optionally, has the graft ligament secured thereto with a cap, whereby to secure the graft ligament to the retainer and hence additionally to the host bone. The present invention also comprises the provision and use of a novel retainer which is slidably advanced to a desired fixation position within a bone tunnel so as to apply a lateral force against the graft ligament so as to compressively hold the graft ligament against the sidewall of the bone tunnel, and which is then locked to the host bone as the graft ligament is simultaneously secured to the retainer, whereby to secure the graft ligament to the retainer and hence additionally to the host bone.

Provided are procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a cartilage plate and cancellous bone tissue attached thereto is removed from a donor bone. The allograft plug is further shaped by removing or cutting away cancellous bone tissue to form a cancellous stalk extending from the cartilage plate. The formed cancellous stalk can have any suitable shape including cylindrical, conical, and rectilnear. At the recipient site of the host bone, a cutout is formed corresponding in shape to the allograft plug. The allograft plug is inserted into the cutout such that the cancellous stalk is retained in the host bone and the cartilage plate aligns with the condyle surface of the host bone. Aspects of the invention may also be applicable to preparing and transplanting osteochondral autograft plugs.

A device and method for biologic vertebral reconstruction utilizes a biologically active jacket inserted into a cavity formed in a vertebra to be reconstructed. An artificial bone material is inserted into the biologically active jacket and allowed to set. The structure and method described herein provide for effective biologic vertebral reconstruction. The use of a biological material and artificial bone enables the host bone to replace the artificial bone over a period of time. Additionally, the structure of the biologically active jacket minimizes any impact into the spinal canal and the paravertebral spaces. Moreover, because of its biomechanical characteristics, which approximate the host bone, there is relative protection of the neighboring vertebral against fracture. Still further, the materials of the biologically active jacket may be impregnated with various substances to achieve various advantageous tasks.

A transverse guide assembly for use in passing a transverse pin through a host bone and through a transversely-extending region formed in an interference screw, wherein the transverse guide assembly includes a key member, a boom member and a guide member, and further wherein the key member is adapted to be connected to a keyway formed in the proximal end of the interference screw, the boom member is connected to the key member and supports the guide member outboard of the interference screw, and the guide member is configured to support a drill for forming a hole to receive the transverse pin which extends transversely through the host bone and the transversely-extending region formed in the interference screw.

A graft ligament is looped through a graft hole in a graft ligament support block, and the graft ligament support block is mounted to an installation tool. Then the installation tool is used to advance the graft ligament support block into a bone tunnel, with the two free ends of the looped graft ligament extending back out the bone tunnel. Next, a transverse tunnel is formed in the host bone, with the transverse tunnel being aligned with a transverse fixation pin hole in the graft ligament support block. Then the graft ligament support block is secured in place by pinning the graft ligament support block within the tunnel, i.e., by advancing a transverse fixation pin along the transverse tunnel and into the transverse fixation pin hole in the graft ligament support block. Then the installation tool is detached from the graft ligament support block and withdrawn from the surgical site.

A new approach for reconstructing a ligament, the new approach comprising: creating a bone tunnel within a host bone, the bone tunnel having a proximal end and a distal end, and defining a central axis extending from the proximal end to the distal end; creating an intervening layer of bone between the central axis of the bone tunnel and a rigid portion of the host bone, the intervening layer having a first side and a second side in opposition to one another, the first side of the intervening layer facing toward the central axis of the bone tunnel and the second side of the intervening layer facing toward the rigid portion of the surrounding host bone; and compressing the intervening layer of bone against a graft ligament positioned within the bone tunnel.

Apparatus for reconstructing a joint, the apparatus comprising:an implant body having a bone contacting surface; anda plurality of fixation elements secured to the implant body and extending into the host bone at a plurality of angles, wherein all angles are not equal to one another, so as to create immediate stability between the implant body and the host bone.

Provided are procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a cartilage plate and cancellous bone tissue attached thereto is removed from a donor bone. The allograft plug is further shaped by removing or cutting away cancellous bone tissue to form a cancellous stalk extending from the cartilage plate. The formed cancellous stalk can have any suitable shape including cylindrical, conical, and rectilinear. At the recipient site of the host bone, a cutout is formed corresponding in shape to the allograft plug. The allograft plug is inserted into the cutout such that the cancellous stalk is retained in the host bone and the cartilage plate aligns with the condyle surface of the host bone. Aspects of the invention may also be applicable to preparing and transplanting osteochondral autograft plugs.

The present invention relates to a method for enhancing ingrowth of host bone comprising: modifying a bone graft structure to provide an ionic gradient to produce a modified bone graft structure; and implanting the modified bone graft structure. The present invention also relates to a method of enhancing the binding of growth factors and cell cultures to a bone graft structure comprising: applying ex vivo an effective quantity of an ionic force change agent to the surface of a bone graft structure to produce a binding-sensitized bone graft structure; implanting the binding-sensitized bone graft structure into a host bone; and administering to the binding-sensitized bone graft structure a molecule, a cell culture or a combination thereof.

Customized implants for use in reconstructive bone surgeries where anatomical accuracy and bone adaptation are important, such as plastic and craniomaxillofacial reconstructions. This implant comprises a porous surface layer and a tough inner core of interpenetrating phase composite. The porous surface layer enhances the biocompatibility, tissue ingrowth, and implant stability. The tough inner core improves the mechanical properties of the implant with a high fracture toughness and a low modulus. The anatomical accuracy of the implants will minimize the intra-operative manipulation required to maintain a stable host bone-implant interface.

A self-positioning and self-starting, tapered thread, orthodontic bone screw (25) for use in intra-oral corrections that serves as a craniomaxillofacial rigid post for orthodontic appliance fixation. The tip of the bone screw incorporates a defined sharp pin-point tack tip (2) to easily pierce the soft tissue and initially penetrate into the host bone for alignment and penetration. In series with the tack tip is a self-tapping, double, tapered thread (11) which allows an orthodontist to insert the bone screw post into the host bone in a single operation without the need for opening or flapping the surrounding soft tissue. As the bone screw penetrates the bone site, the tapered threads (24) allow for easy thread pick-up into the host bone while the increasing outer diameter of the thread (26) rigidly locks into the crestal bone. Once attached and fixated in the host bone, the distal cylindrical dome shaped driver head (12) acts as the fixation post for the anchorage of orthodontic appliances. Incorporated into the cylindrical dome shaped driver head are several attachment features including cross holes (13) and a snap-on undercut groove (19) for attaching orthodontic appliances either individually or simultaneously. The dome shaped head also incorporates a spline driver feature for easy pick-up, assembly and insertion of the screw with a corresponding spline driver tool (27) that allows the screw to be driven with either a standard square or cross slot driver feature.

Provided are procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a cartilage plate and cancellous bone tissue attached thereto is removed from a donor bone. The allograft plug is further shaped by removing or cutting away cancellous bone tissue to form a cancellous stalk extending from the cartilage plate. The formed cancellous stalk can have any suitable shape including cylindrical, conical, and rectilinear. At the recipient site of the host bone, a cutout is formed corresponding in shape to the allograft plug. The allograft plug is inserted into the cutout such that the cancellous stalk is retained in the host bone and the cartilage plate aligns with the condyle surface of the host bone. Aspects of the invention may also be applicable to preparing and transplanting osteochondral autograft plugs.

The present invention relates to medical biological ceramic material technology, and is a kind of artificial bone rack of nano toughened calcium phosphate of high porosity. The present invention has nano zirconia grains added into calcium phosphate to raise the compression strength and toughness of artificial bone rack, so as to provide artificial bone rack of biological ceramic material with high porosity, high compression strength and high toughness. The present invention is prepared through mixing nano zirconia grain with hydroxyapatite in certain ratio to prepare slurry, painting the slurry to polyurethane sponge with proper pore size and porosity and sintering. The present invention has high porosity, proper pore size, easy absorption, fast bone tissue fusion speed and other advantages and is used in repairing damaged bone tissue and extracorporeal cell culture.

A method for enhancing the binding of growth factors and / or cells to an allograft structure by applying an effective quantity of a coating material to the surface of the allograft structure, producing a thin coated allograft structure, administering to the thin coated allograft structure a growth factor, cells or a combination thereof, and implanting the thin coated allograft structure into a host bone.

The invention, for reducing a stress shielding effect after prosthesis implantation, proposes a host bone stress environment based custom prosthesis optimization design method. Three criteria, namely, the strength, the surrounding bone stress and the interface micro-motion between a prosthesis and a bone, in prosthesis elastic modulus optimization calculation are proposed, and the mechanical property of the host bone and a personalized kinematic input are considered in optimization; the prosthesis elastic modulus distribution is optimized through finite element software to achieve the purpose of optimizing a porous structure in the prosthesis; and for the designed prosthesis, on the premise of meeting the strength requirement, the stress shielding effect after implantation is reduced and the service life of the prosthesis after implantation is prolonged.

A method of enhancing the binding of growth factors and cell cultures to a demineralized allograft bone material which includes applying ex vivo an effective quantity of an ionic force change agent to at least a portion of the surface of a demineralized allograft bone material to produce a binding-sensitized demineralized allograft bone material and implanting the binding-sensitized demineralized allograft bone material into a host bone. The ionic force change agent may include at least one of enzymes, pressure, chemicals, heat, sheer force, oxygen plasma, supercritical nitrogen, supercritical carbon, supercritical water or a combination thereof. A molecule, a cell culture, or a combination thereof is administered to the binding-sensitized demineralized allograft bone material.

A graft ligament is looped through a graft hole in a graft ligament support block, and the graft ligament support block is mounted to an installation tool. Then the installation tool is used to advance the graft ligament support block into a bone tunnel, with the two free ends of the looped graft ligament extending back out the bone tunnel. Next, a transverse tunnel is formed in the host bone, with the transverse tunnel being aligned with a transverse fixation pin hole in the graft ligament support block. Then the graft ligament support block is secured in place by pinning the graft ligament support block within the tunnel, i.e., by advancing a transverse fixation pin along the transverse tunnel and into the transverse fixation pin hole in the graft ligament support block. Then the installation tool is detached from the graft ligament support block and withdrawn from the surgical site.

A new approach for reconstructing a ligament, the new approach comprising: creating a bone tunnel within a host bone, the bone tunnel having a proximal end and a distal end, and defining a central axis extending from the proximal end to the distal end; creating an intervening layer of bone between the central axis of the bone tunnel and a rigid portion of the host bone, the intervening layer having a first side and a second side in opposition to one another, the first side of the intervening layer facing toward the central axis of the bone tunnel and the second side of the intervening layer facing toward the rigid portion of the surrounding host bone; and compressing the intervening layer of bone against a graft ligament positioned within the bone tunnel.

A method by which immune responses to cortical bone grafts and other substrates (e.g., cement, IPN, etc.) can be minimized and at the same time graft osteoinductive potential can be improved, and improved graft substrate materials are disclosed. The method of the invention provides new types of bone grafts that incorporate into host bone more thoroughly and more rapidly, eliminating long-term complications, such as fracture, non-union, infection, and rejection. In the method of the invention, bone grafts or other substrates are modified to have an osteoinductive surface modification that the recipient's body will accept as its own tissue type and therefore will not reject or otherwise cause to fail. The osteoinductive surface modification comprises a biopolymer matrix coating that is seeded with periosteal cells that have been previously harvested either from the graft recipient or from an allogenic or xenogenic donor source.

A pin made of cortical bone may be inserted into adjoining bones of a toe to align and secure the bones. The pin may have barbs to prevent migration of the pin. The pin may include a shoulder to further prevent migration of the pin from the bones, to increase the strength of the pin, and to increase the surface area between the bone pin and the host bone. The pin may further include flattened portions on its circumference to aide in rotating the pin during insertion. The pin may be treated to reduce brittleness.

The invention discloses a bioactive ceramic fiber composite scaffold for bone repair and a preparation method of the composite scaffold, and relates to the field of bone repair materials. In order toovercome the shortcomings of large brittleness, difficulty in processing, unsatisfactory degradability and biological activity and the like of a traditional ceramic scaffold material, bioactive ceramics such as calcium silicate serve as a scaffold body, and the surfaces of ceramic fibers are uniformly coated with a layer of degradable biomedical high polymer materials by an impregnation-centrifugation-drying process to obtain a high-porosity, good-mechanical-property and biodegradable bioactive ceramic fiber composite scaffold material for bone repair. The bioactive ceramic materials are easily subjected to synostosis with host bones, inorganic ions released by degrading the bioactive ceramic materials can participate in and promote osteogenesis and even angiogenesis metabolism activity ofa body and have irritating or inducing functions for tissue regeneration repair, and defective bone tissue repair and functional reconstruction are promoted. Degradation products of the biomedical high polymer materials on the surface of the scaffold are harmless and can be excreted to the outside of the body by metabolism.

The invention discloses a zirconia dental implant surface treatment method which comprises the steps of cleaning, sand blasting treatment, acid etching, soaking and sintering. In the invention, the zirconia dental implant surface is dipped with a ball-milled zirconia suspension; the pore diameter of pores in the zirconia dental implant surface is controlled by use of different particle sizes of the ball-milled zirconia powder; meanwhile, due to the sand blasting and acid etching treatment before soaking, the surface roughness of false teeth is increased to certain degree; with later sintering, the surface roughness of false teeth is remarkably increased; and thus, the interfacial effect between the implant material and the host bone can be improved, the binding capacity between the implant and the bone is enhanced, and clinical success rate of dental implant is increased. The zirconia dental implant surface treatment method is simple in operation, convenient in treatment, low in cost and suitable for industrialized large-scale production.

The invention provides a nano calcium silicate-polyetheretherketone (PEEK) composite material which is composed of nano calcium silicate and PEEK in a volume ratio of (10-30):(70-90). The nano calcium silicate-PEEK composite material maintains the excellent biomechanical characteristics of the PEEK, and greatly enhances the biological activity of the PEEK. After being implanted into the body, the nano calcium silicate-PEEK composite material can be matched with peripheral normal bones in the mechanical aspect, can be well integrated with the host bone, promotes the adhesion, proliferation and osteogenesis differentiation of the bone source cells, can keep long-term stability, can be used in clinic as a spine interbody fusion device material and a joint prosthesis material, has active practical meanings, and can generate huge social and economic benefits.

The present invention relates to a method for enhancing ingrowth of host bone comprising: modifying a bone graft structure to provide an ionic gradient to produce a modified bone graft structure; and implanting the modified bone graft structure. The present invention also relates to a method of enhancing the binding of growth factors and cell cultures to a bone graft structure comprising: applying ex vivo an effective quantity of an ionic force change agent to the surface of a bone graft structure to produce a binding-sensitized bone graft structure; implanting said binding-sensitized bone graft structure into a host bone; and administering to said binding-sensitized bone graft structure a molecule, a cell culture or a combination thereof.

The invention relates to a novel artificial hip joint made of porous Ti. A porous Ti material with pore diameter being 400-1000 mu m and porosity being 45%-85% is prepared from Ti6Al4V powder with pore diameter smaller than 100 mu m as raw materials through slurry injection molding and vacuum sintering. The porous Ti material can be taken as a biomimetic bone implantation material and solves the problem of interface loosening between a metal joint and host bone tissue of a bone implantation prosthesis. The artificial hip joint with porous Ti as the surface is designed with the porous Ti material as the core, contact interfaces between the artificial hip joint prosthesis with the porous Ti surface and the host bone tissue are porous Ti, and the artificial hip joint prosthesis specifically comprises a femoral stem with a porous Ti surface layer and a porous Ti acetabular cup. The porous Ti has effects of prompting mesenchymal cells to be transformed into cells of the bone tissue and inducing tissue generation, bones are formed between the interfaces in the early stage, early load of the artificial hip joint prosthesis is effectively increased, and the long-term stability of the artificial hip joint prosthesis after implantation in vivo is effectively improved.

The invention relates to an artificial joint prosthesis with a local grid structure and the manufacturing method thereof, which belongs to the field of biomedicine engineering. The prosthesis comprises a prosthesis handle and a grid structure body, wherein the grid structure comprises a titanium plate and titanium fibers; and the titanium fibers are braided in cross, quadrangular or star shape and sintered on the titanium plate to form the 3D grid structure body with a pore size of 200 to 1,200 mum and a porosity of 30 to 60%. The manufacturing method comprises following steps: braiding and sintering the titanium fibers on the titanium plate to obtain the grid structure body, and welding on the predetermined portion of the joint prosthesis. The method can prevent the prosthesis handle from being subjected to high-temperature thermal processing, maintain good high-strength mechanical property and acquire proper grid structure, thus providing space for the growth of cells and tissue, promoting ankylosing of new-born bone tissue and host bone and achieving bio-fixation of prosthesis. The artificial joint prosthesis can be used for repairing injured joints clinically.

Methods, systems and devices for properly positioning and aligning a prosthetic socket and / or prosthetic ball into host bone structure of a patient using one or more guide shown. Guides implemented according to embodiments may utilize in combination digital IC inclinometer and the laser surgical system with calibrated, reflecting dome.