46 results about "Haemoglobin A1c" patented technology

Provided is a device and a method, said device enabling the measurement of both of blood glucose level and hemoglobin A1c level, being small-sized and thus portable, allowing the measurement of a small amount of a specimen and, therefore, being usable in POC. The device for measuring the blood glucose level and hemoglobin A1c level of a blood specimen comprises: a test piece-mounting section (1) for detachably mounting test pieces (200) on which the blood specimen is to be spotted; a light-emitting section (2) for emitting light for irradiating the test pieces (200); a light-receiving section (3) for receiving reflected lights from the test pieces (200); and an operating section (4) for calculating the blood glucose level and hemoglobin A1c level of the blood specimen on the basis of photometric values obtained from the light-receiving section (3). As a test piece (200) for measuring the blood glucose level of the blood specimen, a test piece (A), which carries a composition (a) reacting with glucose and showing color development, is mounted. As a test piece (200) for measuring the hemoglobin A1c level of the blood specimen, a test piece (B), which carries a composition (b) reacting with glycated hemoglobin and showing color development, is mounted.

Means that enables an immunoassay of hemoglobin A1c in a whole blood sample without pretreatment of the sample is disclosed. The immunoassay of hemoglobin A1c in a sample according to the present invention comprises bringing latex particles into contact with a non-pretreated whole blood sample in a hypotonic solution, and then bringing hemoglobin A1c adsorbed on the latex particles into contact with an anti-hemoglobin A1c antibody. The immunoassay is preferably carried out by an agglutination method. The hypotonic solution is, for example, a buffer containing a Good's buffer at a concentration of 0.02 to 0.2 mol / L, which Good's buffer has the maximum buffer capacity in the neutral to alkaline region.

The disclosure also relates to novel compositions and methods for the single, direct detection of Hemoglobin A1c percentage in a sample, using conversion of functional groups attached to a transitional metal complex, resulting in quantifiable electrochemical signal at two unique potentials, Eo1 and Eo2.