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Hypoglycemic preparation used for human body and its preparation method

A technology for lowering blood sugar, manufacturing method, applied in the field of preparations, to achieve the effect of lowering and treating diabetes, correcting intestinal microbial disturbance, and promoting gastrointestinal function

Inactive Publication Date: 2017-12-15
陈元秀
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although there are many hypoglycemic drugs including insulin at present, due to the fact that type 2 diabetes continues to deteriorate with age, and diet and other living habits cannot be easily changed, patients who can really control blood sugar not much

Method used

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  • Hypoglycemic preparation used for human body and its preparation method
  • Hypoglycemic preparation used for human body and its preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] According to eight kinds of probiotics in table 1., make eight kinds of single joint probiotics capsule preparations respectively (each dose only contains a kind of probiotics), but the dose of single bacterium is 10 7 CFU. Use the probiotic capsule preparation to observe the effect in diabetic patients. 50-70-year-old diabetic patients were randomly selected. The current blood sugar control is not good, and the blood sugar level is between 8 and 11 mmol. Patients were randomly divided into eight groups, 16 people in each group. Patients took one capsule daily for three months. Blood samples were taken before and after taking, and the content of hemoglobin A1c was detected. The results are shown in Table 2.

[0054] Table 2. Therapeutic effect of individual probiotic preparations on hemoglobin A1c

[0055] Probiotic name

Before treatment

After treatment

Δ mean

Lactobacillus acidophilus

9.4

9.21

0.19*

Lactobacillus plantar...

Embodiment 2

[0059] According to the probiotics and corresponding doses in Table 3., we have prepared eight probiotic preparations, and the number of probiotics in each capsule is 8×10 12 CFU. Also use the probiotic capsule preparation to observe the effect in diabetic patients. Randomly select 16 diabetic patients aged 50-70, whose current blood sugar control is not good, and the blood sugar level is between 8 and 11 mmol. Patients took one capsule daily for three months. Blood samples were taken before and after taking, and the content of hemoglobin A1c was detected.

[0060] Table 3. The name of the eight-linked probiotics and the number of bacteria in the preparation

[0061] Probiotic name

English name of probiotics

The number of bacteria in probiotic preparations (CFU)

Lactobacillus acidophilus

Lactobacillus acidophilus

10 12

Lactobacillus plantarum

Lactobacillus plantarum

10 12

Lactobacillus rhamnosus

Lactobacillus rhamnos...

Embodiment 3

[0068] According to the probiotics listed in Table 3. and the corresponding doses, we selected seven, six, five, four, three and two different probiotics according to the random principle to make seven and six combinations respectively. , Wulian, Quadruple, Triple, and Duplex probiotic preparations. The total number of probiotics in each preparation is the same as in Example 2, that is, the number of probiotics in each capsule is still 8×10 10 CFU. Also use the probiotic capsule preparation to observe the effect in diabetic patients. Randomly select 16 diabetic patients aged 50-70 years old, the current blood sugar control is not good, the blood sugar level is between 8-11 mmol. The patient took a dose of probiotic capsules in Table 5 every day for three consecutive months. Blood samples were taken before and after taking, and the content of hemoglobin A1c was detected. The result is displayed as follows:

[0069] Table 5. Observation of the effect of multiple probiotic p...

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Abstract

The invention provides a hypoglycemic preparation for the human body. The hypoglycemic preparation includes at least one kind of probiotics, and the amount of each kind of probiotics is 107-1013 CFU, and the total amount of the probiotics in each hypoglycemic preparation is 8*107-8*1013 CFU. The invention further discloses a preparation method of a hypoglycemic preparation used for the human body. According to the hypoglycemic preparation used for the human body and its preparation method, the gastrointestinal function can be promoted, the body's immune system is regulated so as to correct the intestinal microbial disturbance, and the preparation has the effects of reducing hemoglobin A1c and treating the diabetes.

Description

technical field [0001] The invention relates to the field of preparations, in particular to a hypoglycemic preparation for human body and a preparation method thereof. Background technique [0002] Type II diabetes is one of the main diseases that endanger people's health in modern society. According to relevant reports, there are about 120 million diabetic patients in China, and this number is still increasing year by year. The blood sugar control of most diabetic patients fails to reach the level expected by doctors, that is, hemoglobin A1c<7.0 (normal value A1c<5.7), in order to prevent the occurrence of diabetic complications as much as possible. The direct consequence of poor blood sugar control is the occurrence of diabetic syndrome, including: amputation, blindness, renal failure, heart disease and other cardiovascular system diseases. Therefore, strict control of blood sugar is a necessary condition to effectively prevent diabetic syndrome and ensure the norm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/747A61P3/10C12N1/20C12Q1/68C12Q1/04C12Q1/06C12R1/01C12R1/23C12R1/25C12R1/225C12R1/245A61K35/745
CPCA61K35/745A61K35/747C12N1/20C12Q1/06C12Q1/689A61K2300/00
Inventor 陈元秀
Owner 陈元秀
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