30 results about "Demodex" patented technology

The present invention relates to a method for treating a disorder chosen from ocular Demodex, Demodex-induced blepharitis, rosacea, acne, and meibomian gland dysfunction in a patient in need thereof, comprising administering to the patient a composition comprising a therapeutically effective amount of a substance chosen from at least one of an isoprenoidal essential oil such as Tea Tree Oil; Terpinen-4-ol; (+)-Carvone; alpha-Terpineol; Cardinene; d-Carvone; l-Carvone; gamma-Terpinene; alpha-Terpinene; 1,8-Cineole; alpha-Terpineol; para-Cimene; alpha-Pinene; Limonene; (R)-(+)-Limonene; alpha-Thugene; Eucalyptol; (+)-Ledene; Cuminic Aldehyde; and Myrcene; the administration comprising contacting or scrubbing an affected area of skin or hair, or eyelid margin and lashes of the patient with the composition; also disclosed are a method for treating mange and mite infestations on a mammalian animal; and kits for in-office and at home treatments of the disorders.

The invention discloses a composition for preparing a camel milk facial mask, and particularly a composition for preparing a camel milk moisturizing skin-calming facial mask, a camel milk moisturizing clear facial mask, a camel milk moisturizing compact facial mask and a camel milk moisturizing conditioning facial mask according to functions. By virtue of the synergism of camel milk, water, sodium carbomer, glycerinum, xanthan gum, butanediol, sodium hyaluronate, poly(sodium L-glutamate), skin conditioner and preservative, the characteristics and advantages of the camel milk are maximally maintained, so that the composition for preparing the cameral milk facial mask has the advantages of the camel milk, namely, proteins, vitamins, minerals and fatty acid rich in the composition can provide rich nutrient substances for the skin and can improve the face skin; particularly, the camel milk contains lactoferrin and lysozyme which are short in cow milk, so that the composition has the effects of sterilizing, killing demodex, removing toxicity, softening stratum corneum epidermidis, moisturizing and tendering the skin, preventing wrinkles and aging resistance, and delaying senescence.

Compositions containing about 0.6% to about 20% of tea tree oil are described. Some compositions are in the form of solutions, suspensions, spray, lotions, gels, pastes, medicated sticks, balms, cleansers (including shampoos and soaps), creams, or ointments. Also described are compositions and methods for use in treating ocular Demodex infestations and related conditions using such compositions.

Compositions containing about 0.6% to about 20% of tea tree oil are described. Some compositions are in the form of solutions, suspensions, spray, lotions, gels, pastes, medicated sticks, balms, cleansers (including shampoos and soaps), creams, or ointments. Also described are compositions and methods for use in treating ocular Demodex infestations and related conditions using such compositions.

Formulation of ectoparasiticidal and antibiotic “compositions into pharmaceutical compositions useful for the treatment of eyelid inflammation, in particular demodex related blepharitis and eye crusting.

The present invention concerns materials and methods for treating an ocular Demodex mite infestation of an eye of a human or animal subject, or for treating a condition of the eye or skin associated with ocular Demodex mite infestation, the method comprising topically administering a composition comprising one or more spinosyn compounds to the ocular surface (conjunctiva and / or cornea) or other anatomical structure of the eye, or to an area adjacent the eye.

Embodiments of the invention involve treating skin afflictions by the topical or oral use of acetylcholinesterase inhibitor. By effectively reducing or eliminating the population of Demodex mites in affected skin areas and areas where Demodex mites may exist, this treatment achieves a more complete remission of clinical signs and symptoms of the skin afflictions than any previously described method. Embodiments of the invention are useful for treating skin afflictions including common acne, seborrheic dermatitis, perioral dermatitis, an acneform rash, transient acantholytic dermatosis, acne necrotica milliaris, psoriasis, steroid induced dermatitis, primary irritation dermatitis and rosacea.

The present invention relates to a method for treating a disorder chosen from ocular Demodex, Demodex-induced blepharitis, rosacea, acne, and meibomian gland dysfunction in a patient in need thereof, comprising administering to the patient a composition comprising a therapeutically effective amount of a substance chosen from at least one of an isoprenoidal essential oil such as Tea Tree Oil; Terpinen-4-ol; Carvone; alpha-Terpineol; Cardinene; d-Carvone; l-Carvone; gamma-Terpinene; alpha-Terpinene; 1,8-Cineole; alpha-Terpineol; para-Cimene; alpha-Pinene; Limonene; (R)-(+)-Limonene; alpha-Thugene; Eucalyptol; (+)-Ledene; Cuminic Aldehyde; and Myrcene; the administration comprising contacting or scrubbing an affected area of skin or hair, or eyelid margin and lashes of the patient with the composition; also disclosed are a method for treating mange and mite infestations on a mammalian animal; and kits for in-office and at home treatments of the disorders.

A composition for the treatment of Demodex blepharitis containing tea tree oil and / or Neem oil and coconut oil in glycerol or in water or in a mixture of glycerol and water. The composition may further contain aloe barbadensis gel, sodium lauryl sulfate, cocoamidopropyl betaine, lauroyl glucoside, or DMDM hydantoin, or a combination thereof, in glycerol or in water or in a mixture of glycerol and water. The composition is used to treat Demodex blepharitis by applying the composition to the eyelid margin and eyelashes and scrubbing the eyelid margin, eyelashes, and eyelash roots with the composition using any suitable cloth, wipe, sponge, brush, or cotton tipped applicator.

The invention discloses a method for establishing a demodex-caused rosacea-like skin lesion animal model. The method includes the steps of cleaning and drying the skin of a facial-demodex-positive mite donor, squeezing and scraping the wings of a nose or a face to obtain sebum secretion, cleaning the squeezed secretion to prepare demodex protozoon suspension, and intradermally injecting the demodex protozoon suspension into a 4 cm*4 cm experimental area of the back of a Japanese rabbit. In order to solve the problems that the reactivity of an existing rabbit to the natural infection approach of human demodex is quite small and there is a lack of the demodex-caused rosacea-like skin lesion animal model, the Japanese rabbit species is adopted and demodex protozoon is inoculated intradermally, and the demodex-caused rosacea-like skin lesion animal model is established; the clinical expression and histopathological expression of erythema, papule and skin lesion highly similar to rosacea of demodex-positive people can be observed through the skin lesion of the Japanese rabbit, and the requirement of using the Japanese rabbit as the demodex-caused rosacea-like skin lesion animal model is met.

The invention relates to compositions and kits for treating infections caused by the mite Demodex Spp, said compositions comprising essential oils selected from the group consisting of Eruca sativa oil, Zingiber officinale oil, and Alpinia officinarum oil and mixtures thereof incorporated into solvents and vehicles, and presented in a kit in the form of a solution, a suspension, an emulsion or a dispersion. The compositions are topically applied for the treatment of infections and disorders caused by Demodex Spp in humans.

The invention discloses an external formula for treating facial inflammatory skin diseases. The external formula consists of the following raw material medicines preparing the active ingredients in parts by weight: 1-10 parts of borneol, 10-30 parts of fructus cnidii, 10-30 parts of radix sophorae flavescentis, 5-15 parts of dried alum, 1-10 parts of realgar, 10-20 parts of oyster, 5-15 parts of Scutellaria baicalensis, 5-15 parts of Schizonepeta, 10-40 parts of isatis root, 5-15 parts of mint, 5-15 parts of fructus forsythiae, 10-20 parts of Chinese parsnip root, 5-15 parts of the tuber of stemona, 5-15 parts of honeysuckle, 5-15 parts of cicada slough, 5-15 parts of rattletop, 10-40 parts of astragalus, 5-15 parts of angelica sinensis and 5-15 parts of fructus kochiae. The external formula disclosed by the invention is a pure Chinese herbal medicine formula, has the effects of killing demodex, shrinking blood capillary and controlling grease secretion and inflammations and is suitable for treating facial inflammatory skin diseases such as acnes, seborrheic dermatitis and rosacea. According to the external formula, pathogenesis is corrected, the cure rate is increased, and complete rehabilitation is realized.

Described are stable topical formulations useful in the treatment of viral infection, demodex infection and bacterial infection of the eye, and methods of using the compositions for treating viral infection, demodex infection and bacterial infection of the eye.

The invention discloses a composition for treating blepharitis and a preparing method thereof and belongs to the technical field of medicine. The composition is prepared from rheum officinale, radix sophorae flavescentis, cortex dictamni, raw liquorice and metronidazole disodium phosphate. All the bulk drugs are easy to obtain, the composition compatibility is scientific, and quality is controllable; all the raw materials in the composition have a synergistic effect, the composition carries out insecticide and sterilization aiming at pathogeny and pathogenesis causing the demodex blepharitis, takes effect fast, achieves the purpose of treating the demodex blepharitis fast, and is suitable for large groups of people and good in curative effect, and the blepharitis does not relapse easily after healing.

The invention relates to the technical field of plasters, and in particular discloses an anti-allergic ointment formula, which is prepared from the following raw materials in parts by weight: 15-25 parts of diphenhydramine hydrochloride, 3-5 parts of prednisone acetate, benzocarb 15-25 parts of glycerin, 70-80 parts of glycerin, 100-120 parts of stearic acid, 8-12 parts of 10% ethylparaben solution, 70-80 parts of glyceryl monostearate, 3-5 parts of essence, white Vaseline 80-120 parts, distilled water 550-600 parts, polysorbate-80 25-35 parts. The invention overcomes the disadvantages of the prior art, has the functions of killing demodex and scabies, anti-bacteria, anti-inflammation, anti-allergy and antipruritic, and is used for treating allergic and pruritus skin diseases.

A method of characterizing specific microbiota associated with Demodex mites from a rosacea patient is described. The method can include a step of realizing a biopsy on the patient and analyzing the microbiota based on a method of 16SrRNA sequencing or pyrosequencing. A method for the diagnosis of rosacea in a patient is also described. This method can include characterizing microbiota associated with Demodex mites in the patient. Also described, are methods of differentiating a subtype of rosacea in a patient with rosacea and methods of controlling and measuring an active agent's treatment effectiveness on rosacea.

Described are stable topical formulations useful in the treatment of viral wart infection, demodex infection and bacterial infection of the skin, and genitalia and the method of treating viral wart infection, demodex infection and bacterial infection of the skin, and genitalia with said compositions.

The invention discloses a composition for treating blepharitis and a preparing method thereof and belongs to the technical field of medicine. The composition is prepared from rheum officinale, radix sophorae flavescentis, cortex dictamni, raw liquorice and metronidazole disodium phosphate. All the bulk drugs are easy to obtain, the composition compatibility is scientific, and quality is controllable; all the raw materials in the composition have a synergistic effect, the composition carries out insecticide and sterilization aiming at pathogeny and pathogenesis causing the demodex blepharitis, takes effect fast, achieves the purpose of treating the demodex blepharitis fast, and is suitable for large groups of people and good in curative effect, and the blepharitis does not relapse easily after healing.

The present invention relates to the treatment of an ocular inflammatory disease or an ocular degeneration disease by ophthalmic administration of a composition comprising tapinarof and optionally at least one additional active agent. Specifically, the ocular inflammatory disease is blepharitis. This invention provides a treatment of blepharitis and Demodex mites.

A method of characterizing specific microbiota associated with Demodex mites from a rosacea patient is described. The method can include a step of realizing a biopsy on the patient and analyzing the microbiota based on a method of 16SrRNA sequencing or pyrosequencing. A method for the diagnosis of rosacea in a patient is also described. This method can include characterizing microbiota associated with Demodex mites in the patient. Also described, are methods of differentiating a subtype of rosacea in a patient with rosacea and methods of controlling and measuring an active agent's treatment effectiveness on rosacea.

The invention provides a pyridaben-containing granule type pesticide which comprises the following formula components in percentage by mass: 50% of flutenzine, 8% of pyridaben, 1% of emulsifier, 1% of a solvent, 1% of a cosolvent and the balance of deionized water. Pyridaben has a good synergistic effect, so that the pyridaben-containing granule type pesticide has a synergistic interaction effect, is low in using cost, has a good prevention effect, is wide in demodex killing spectrum, strong in adaptability, long in lasting period, low in toxicity, low in residue, good in safety and strong in compatibility, and can kill both eggs and larva.

Described are stable topical formulations useful in the treatment of viral wart infection, demodex infection and bacterial infection of the skin, and genitalia and the method of treating viral wart infection, demodex infection and bacterial infection of the skin, and genitalia with said compositions.

Described are stable topical formulations useful in the treatment of viral wart infection, demodex infection and bacterial infection of the skin, and genitalia and the method of treating viral wart infection, demodex infection and bacterial infection of the skin, and genitalia with said compositions.

The invention relates to a feed for preventing porcine demodex disease. The feed is characterized by being prepared from the following raw materials in parts by weight: 450-480 parts of corns, 120-140parts of broken rice, 120-150 parts of soybean meal, 50-70 parts of germ meal, 120-140 parts of a tapioca powder, 10-20 parts of a zeolite powder, 5-10 parts of bone meal, 5-10 parts of a garlic powder, 8-12 parts of radix rehmanniae recens, 6-10 parts of ligusticum wallichii, 10-15 parts of radix paeoniae rubrathe, 6-10 parts of flos magnolia, 8-12 parts of clove, 8-12 parts of radix stemonae, 6-10 parts of licorice and 8-12 parts of angelica sinensis. The feed is capable of better preventing the porcine demodex disease, enhancing the immunity and promoting the growth and development.

Described are stable topical formulations useful in the treatment of viral infection, demodex infection, fungal infection and bacterial infection of the eye, and methods of using the compositions for treating viral infection, demodex infection, fungal infection and bacterial infection of the eye.

The invention relates to providing a health-care perfume, which is made of the following raw materials in parts by weight: 15-25 parts of musk, 10-25 parts of plant essential oil, 15-20 parts of fixative, and 10-15 parts of sodium alginate , 12-18 parts of Chinese herbal medicine absorption enhancer, 8-15 parts of ethanol, 15-35 parts of water, 5-18 parts of aromatic alcohol, 2-8 parts of citric acid. The health-care perfume of the present invention is formulated by adding plant essential oils. The fragrance is elegant and natural, and the fragrance lasts for a long time, and can effectively kill Demodex and protect skin health; the fragrance of the present invention is pleasant, and the fragrance lasts for a long time. Perfume can make people feel relieved, invigorate blood circulation and clear mind.

The invention relates to compositions and kits for treating infections caused by the mite Demodex Spp, said compositions comprising essential oils selected from the group consisting of Eruca sativa oil, Zingiber officinale oil, and Alpinia officinarum oil and mixtures thereof incorporated into solvents and vehicles, and presented in a kit in the form of a solution, a suspension, an emulsion or a dispersion. The compositions are topically applied for the treatment of infections and disorders caused by Demodex Spp in humans.