The invention provides an anaerobic digestion sludge conditioning system. The anaerobic digestion sludge conditioning system comprises a sludge storage tank, a heating tank, an anaerobic digestion system, a methane purification device, a methane utilization device, a sludge concentration dewatering device, and a pyrohydrolysis reaction tank; the sludge storage tank, the heating tank, and the anaerobic digestion system are communicated successively; the anaerobic digestion system is communicated with the methane purification device and the sludge concentration dewatering device respectively; the sludge concentration dewatering device is communicated with the heating tank and the pyrohydrolysis reaction tank respectively; the methane purification device is communicated with the methane utilization device; the methane utilization device is communicated with the anaerobic digestion system and the pyrohydrolysis reaction tank respectively; and the pyrohydrolysis reaction tank is communicated with the heating tank. According to the anaerobic digestion sludge conditioning system, postposition pyrohydrolysis is adopted, so that energy consumed on the part of sludge easy for biodegradation in the prior art is transferred to the part of sludge difficult for biodegradation, biogas production efficiency is increased, energy utilization efficiency is increased greatly, and a large amount of operation cost is reduced for practical engineering.